LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IFQ1_LEIDO
TriTrypDb:
LdBPK_230250.1 , LdCL_230007400 , LdCL_230007900 , LDHU3_23.0320
Length:
152

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

A0A3Q8IFQ1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFQ1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 2 4 PF00675 0.498
CLV_PCSK_KEX2_1 126 128 PF00082 0.653
CLV_PCSK_KEX2_1 2 4 PF00082 0.498
CLV_PCSK_PC1ET2_1 126 128 PF00082 0.653
CLV_PCSK_SKI1_1 46 50 PF00082 0.414
CLV_PCSK_SKI1_1 8 12 PF00082 0.484
DEG_Nend_UBRbox_1 1 4 PF02207 0.674
DOC_CKS1_1 67 72 PF01111 0.679
DOC_PP1_RVXF_1 1 8 PF00149 0.681
DOC_PP4_FxxP_1 109 112 PF00568 0.405
DOC_USP7_MATH_1 20 24 PF00917 0.703
DOC_WW_Pin1_4 66 71 PF00397 0.677
DOC_WW_Pin1_4 83 88 PF00397 0.603
LIG_14-3-3_CanoR_1 25 31 PF00244 0.690
LIG_14-3-3_CanoR_1 60 67 PF00244 0.654
LIG_BRCT_BRCA1_1 44 48 PF00533 0.681
LIG_FHA_2 84 90 PF00498 0.696
LIG_FHA_2 9 15 PF00498 0.632
LIG_RPA_C_Fungi 55 67 PF08784 0.499
LIG_SH2_STAT5 116 119 PF00017 0.525
LIG_SH3_3 64 70 PF00018 0.544
LIG_SUMO_SIM_anti_2 102 108 PF11976 0.405
MOD_CDK_SPxK_1 66 72 PF00069 0.589
MOD_CK1_1 23 29 PF00069 0.635
MOD_CK1_1 52 58 PF00069 0.631
MOD_CK2_1 141 147 PF00069 0.773
MOD_CK2_1 83 89 PF00069 0.615
MOD_CK2_1 92 98 PF00069 0.561
MOD_GlcNHglycan 118 121 PF01048 0.537
MOD_GlcNHglycan 17 20 PF01048 0.595
MOD_GlcNHglycan 36 39 PF01048 0.600
MOD_GlcNHglycan 52 55 PF01048 0.559
MOD_GlcNHglycan 57 60 PF01048 0.692
MOD_GlcNHglycan 98 102 PF01048 0.405
MOD_GSK3_1 20 27 PF00069 0.628
MOD_GSK3_1 36 43 PF00069 0.615
MOD_GSK3_1 44 51 PF00069 0.592
MOD_GSK3_1 92 99 PF00069 0.562
MOD_NEK2_1 36 41 PF00069 0.543
MOD_NEK2_1 42 47 PF00069 0.530
MOD_NEK2_1 48 53 PF00069 0.490
MOD_NEK2_2 20 25 PF00069 0.587
MOD_PKA_2 24 30 PF00069 0.576
MOD_PKA_2 92 98 PF00069 0.610
MOD_Plk_4 29 35 PF00069 0.541
MOD_Plk_4 99 105 PF00069 0.417
MOD_ProDKin_1 66 72 PF00069 0.589
MOD_ProDKin_1 83 89 PF00069 0.488
MOD_SUMO_rev_2 119 128 PF00179 0.549
MOD_SUMO_rev_2 144 152 PF00179 0.677
TRG_ER_diArg_1 1 3 PF00400 0.617
TRG_ER_diArg_1 80 83 PF00400 0.638

Homologs

Protein Taxonomy Sequence identity Coverage
A4HCN6 Leishmania braziliensis 64% 100%
A4I061 Leishmania infantum 100% 100%
E9ACS2 Leishmania major 91% 100%
E9AW24 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS