LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IFJ3_LEIDO
TriTrypDb:
LdBPK_292750.1 , LdCL_290033600 , LDHU3_29.4060
Length:
441

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IFJ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFJ3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 422 424 PF00675 0.365
CLV_PCSK_KEX2_1 422 424 PF00082 0.365
CLV_PCSK_SKI1_1 175 179 PF00082 0.391
CLV_PCSK_SKI1_1 318 322 PF00082 0.351
CLV_PCSK_SKI1_1 400 404 PF00082 0.382
DEG_COP1_1 290 297 PF00400 0.464
DEG_SCF_SKP2-CKS1_1 212 219 PF00560 0.467
DOC_CYCLIN_RxL_1 420 429 PF00134 0.397
DOC_MAPK_gen_1 347 354 PF00069 0.438
DOC_MAPK_MEF2A_6 292 299 PF00069 0.481
DOC_MAPK_MEF2A_6 347 354 PF00069 0.473
DOC_MAPK_MEF2A_6 88 95 PF00069 0.437
DOC_PP1_RVXF_1 421 428 PF00149 0.489
DOC_USP7_MATH_1 146 150 PF00917 0.545
DOC_USP7_MATH_1 181 185 PF00917 0.578
DOC_USP7_MATH_1 202 206 PF00917 0.400
DOC_USP7_UBL2_3 362 366 PF12436 0.495
DOC_WW_Pin1_4 142 147 PF00397 0.586
DOC_WW_Pin1_4 213 218 PF00397 0.523
LIG_14-3-3_CanoR_1 175 181 PF00244 0.403
LIG_14-3-3_CanoR_1 230 235 PF00244 0.490
LIG_14-3-3_CanoR_1 391 399 PF00244 0.493
LIG_14-3-3_CanoR_1 75 83 PF00244 0.502
LIG_Actin_WH2_2 383 399 PF00022 0.504
LIG_BIR_II_1 1 5 PF00653 0.577
LIG_CaM_IQ_9 222 238 PF13499 0.480
LIG_DLG_GKlike_1 230 238 PF00625 0.400
LIG_EVH1_1 258 262 PF00568 0.350
LIG_FAT_LD_1 48 56 PF03623 0.536
LIG_FHA_1 219 225 PF00498 0.435
LIG_FHA_1 270 276 PF00498 0.455
LIG_FHA_1 319 325 PF00498 0.340
LIG_FHA_1 336 342 PF00498 0.515
LIG_FHA_1 346 352 PF00498 0.327
LIG_FHA_1 382 388 PF00498 0.506
LIG_FHA_1 401 407 PF00498 0.528
LIG_FHA_1 64 70 PF00498 0.524
LIG_FHA_1 85 91 PF00498 0.441
LIG_FHA_2 427 433 PF00498 0.396
LIG_FHA_2 79 85 PF00498 0.525
LIG_GBD_Chelix_1 136 144 PF00786 0.338
LIG_GBD_Chelix_1 203 211 PF00786 0.395
LIG_LIR_Gen_1 239 248 PF02991 0.404
LIG_LIR_Gen_1 296 303 PF02991 0.476
LIG_LIR_Gen_1 359 368 PF02991 0.543
LIG_LIR_Nem_3 183 189 PF02991 0.584
LIG_LIR_Nem_3 239 244 PF02991 0.430
LIG_LIR_Nem_3 296 302 PF02991 0.403
LIG_LIR_Nem_3 359 363 PF02991 0.461
LIG_NRBOX 297 303 PF00104 0.468
LIG_PDZ_Class_2 436 441 PF00595 0.576
LIG_Pex14_1 431 435 PF04695 0.369
LIG_Pex14_2 427 431 PF04695 0.468
LIG_SH2_GRB2like 368 371 PF00017 0.622
LIG_SH2_NCK_1 368 372 PF00017 0.624
LIG_SH2_STAP1 73 77 PF00017 0.530
LIG_SH2_STAT3 223 226 PF00017 0.474
LIG_SH2_STAT5 11 14 PF00017 0.559
LIG_SH2_STAT5 223 226 PF00017 0.474
LIG_SH2_STAT5 356 359 PF00017 0.469
LIG_SH2_STAT5 368 371 PF00017 0.624
LIG_SH2_STAT5 420 423 PF00017 0.397
LIG_SH2_STAT5 426 429 PF00017 0.386
LIG_SH3_1 256 262 PF00018 0.430
LIG_SH3_3 140 146 PF00018 0.400
LIG_SH3_3 194 200 PF00018 0.510
LIG_SH3_3 256 262 PF00018 0.430
LIG_SH3_3 55 61 PF00018 0.529
LIG_SUMO_SIM_anti_2 245 253 PF11976 0.481
LIG_SUMO_SIM_anti_2 272 277 PF11976 0.400
LIG_SUMO_SIM_anti_2 348 355 PF11976 0.379
LIG_SUMO_SIM_par_1 110 116 PF11976 0.488
LIG_SUMO_SIM_par_1 348 355 PF11976 0.467
LIG_SUMO_SIM_par_1 91 97 PF11976 0.440
LIG_TRAF2_1 61 64 PF00917 0.583
LIG_TRAF2_1 77 80 PF00917 0.315
LIG_WRC_WIRS_1 203 208 PF05994 0.478
MOD_CDK_SPxK_1 213 219 PF00069 0.467
MOD_CK1_1 169 175 PF00069 0.428
MOD_CK1_1 210 216 PF00069 0.363
MOD_CK1_1 325 331 PF00069 0.546
MOD_CK1_1 59 65 PF00069 0.484
MOD_CK1_1 78 84 PF00069 0.530
MOD_CK2_1 181 187 PF00069 0.405
MOD_CK2_1 339 345 PF00069 0.554
MOD_CK2_1 426 432 PF00069 0.388
MOD_CK2_1 78 84 PF00069 0.521
MOD_GlcNHglycan 171 174 PF01048 0.483
MOD_GlcNHglycan 183 186 PF01048 0.401
MOD_GlcNHglycan 304 308 PF01048 0.545
MOD_GlcNHglycan 324 327 PF01048 0.368
MOD_GlcNHglycan 341 344 PF01048 0.537
MOD_GlcNHglycan 75 78 PF01048 0.405
MOD_GSK3_1 142 149 PF00069 0.565
MOD_GSK3_1 165 172 PF00069 0.452
MOD_GSK3_1 303 310 PF00069 0.472
MOD_GSK3_1 318 325 PF00069 0.328
MOD_GSK3_1 335 342 PF00069 0.466
MOD_GSK3_1 59 66 PF00069 0.517
MOD_N-GLC_1 169 174 PF02516 0.486
MOD_N-GLC_1 277 282 PF02516 0.454
MOD_N-GLC_1 369 374 PF02516 0.649
MOD_NEK2_1 113 118 PF00069 0.362
MOD_NEK2_1 165 170 PF00069 0.476
MOD_NEK2_1 224 229 PF00069 0.465
MOD_NEK2_1 276 281 PF00069 0.431
MOD_NEK2_1 302 307 PF00069 0.497
MOD_NEK2_1 51 56 PF00069 0.497
MOD_NEK2_1 94 99 PF00069 0.420
MOD_PIKK_1 260 266 PF00454 0.568
MOD_PIKK_1 307 313 PF00454 0.377
MOD_PIKK_1 325 331 PF00454 0.510
MOD_PIKK_1 75 81 PF00454 0.422
MOD_PKA_2 229 235 PF00069 0.485
MOD_PKA_2 335 341 PF00069 0.571
MOD_PKA_2 5 11 PF00069 0.675
MOD_Plk_1 277 283 PF00069 0.459
MOD_Plk_4 139 145 PF00069 0.584
MOD_Plk_4 202 208 PF00069 0.468
MOD_Plk_4 219 225 PF00069 0.471
MOD_ProDKin_1 142 148 PF00069 0.588
MOD_ProDKin_1 213 219 PF00069 0.524
MOD_SUMO_rev_2 394 399 PF00179 0.494
MOD_SUMO_rev_2 57 66 PF00179 0.554
MOD_SUMO_rev_2 76 83 PF00179 0.308
TRG_DiLeu_BaEn_1 359 364 PF01217 0.498
TRG_DiLeu_BaLyEn_6 89 94 PF01217 0.464
TRG_ER_diArg_1 31 34 PF00400 0.574
TRG_ER_diArg_1 347 350 PF00400 0.502
TRG_ER_diArg_1 421 423 PF00400 0.369

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6Y5 Leptomonas seymouri 51% 96%
A0A0S4IKI5 Bodo saltans 27% 97%
A0A1X0P918 Trypanosomatidae 35% 95%
A0A3R7K871 Trypanosoma rangeli 38% 100%
A4HHR2 Leishmania braziliensis 79% 100%
A4I4X2 Leishmania infantum 100% 100%
C9ZKY1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AEC6 Leishmania major 94% 100%
E9ALG0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
V5BSL0 Trypanosoma cruzi 37% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS