LeishMANIAdb
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Mucin-like glycoprotein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mucin-like glycoprotein, putative
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IFJ2_LEIDO
TriTrypDb:
LdBPK_312750.1 * , LdCL_310035500 , LDHU3_31.4860
Length:
680

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 4
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

A0A3Q8IFJ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFJ2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 492 496 PF00656 0.733
CLV_C14_Caspase3-7 96 100 PF00656 0.440
CLV_NRD_NRD_1 266 268 PF00675 0.443
CLV_NRD_NRD_1 445 447 PF00675 0.566
CLV_NRD_NRD_1 674 676 PF00675 0.470
CLV_PCSK_KEX2_1 266 268 PF00082 0.505
CLV_PCSK_KEX2_1 339 341 PF00082 0.590
CLV_PCSK_KEX2_1 445 447 PF00082 0.540
CLV_PCSK_KEX2_1 674 676 PF00082 0.470
CLV_PCSK_PC1ET2_1 339 341 PF00082 0.590
CLV_PCSK_SKI1_1 283 287 PF00082 0.555
CLV_PCSK_SKI1_1 304 308 PF00082 0.525
CLV_PCSK_SKI1_1 448 452 PF00082 0.531
DEG_SPOP_SBC_1 103 107 PF00917 0.601
DEG_SPOP_SBC_1 123 127 PF00917 0.496
DEG_SPOP_SBC_1 133 137 PF00917 0.530
DEG_SPOP_SBC_1 143 147 PF00917 0.440
DEG_SPOP_SBC_1 153 157 PF00917 0.426
DEG_SPOP_SBC_1 163 167 PF00917 0.451
DEG_SPOP_SBC_1 173 177 PF00917 0.431
DEG_SPOP_SBC_1 183 187 PF00917 0.435
DEG_SPOP_SBC_1 193 197 PF00917 0.481
DEG_SPOP_SBC_1 203 207 PF00917 0.455
DEG_SPOP_SBC_1 213 217 PF00917 0.434
DEG_SPOP_SBC_1 4 8 PF00917 0.654
DOC_ANK_TNKS_1 618 625 PF00023 0.771
DOC_CKS1_1 407 412 PF01111 0.819
DOC_CKS1_1 548 553 PF01111 0.847
DOC_MAPK_DCC_7 396 406 PF00069 0.827
DOC_MAPK_FxFP_2 641 644 PF00069 0.719
DOC_MAPK_gen_1 396 406 PF00069 0.827
DOC_MAPK_gen_1 505 514 PF00069 0.787
DOC_MAPK_MEF2A_6 399 406 PF00069 0.819
DOC_MAPK_RevD_3 252 267 PF00069 0.478
DOC_PP1_RVXF_1 60 66 PF00149 0.531
DOC_PP2B_LxvP_1 330 333 PF13499 0.844
DOC_PP2B_LxvP_1 416 419 PF13499 0.826
DOC_PP2B_LxvP_1 531 534 PF13499 0.760
DOC_PP2B_LxvP_1 565 568 PF13499 0.658
DOC_PP2B_LxvP_1 75 78 PF13499 0.531
DOC_PP4_FxxP_1 641 644 PF00568 0.782
DOC_USP7_MATH_1 101 105 PF00917 0.539
DOC_USP7_MATH_1 218 222 PF00917 0.564
DOC_USP7_MATH_1 331 335 PF00917 0.766
DOC_USP7_MATH_1 4 8 PF00917 0.675
DOC_USP7_MATH_1 46 50 PF00917 0.467
DOC_USP7_MATH_1 496 500 PF00917 0.692
DOC_USP7_MATH_1 518 522 PF00917 0.726
DOC_USP7_MATH_1 642 646 PF00917 0.813
DOC_USP7_MATH_1 92 96 PF00917 0.606
DOC_WW_Pin1_4 10 15 PF00397 0.642
DOC_WW_Pin1_4 220 225 PF00397 0.597
DOC_WW_Pin1_4 334 339 PF00397 0.846
DOC_WW_Pin1_4 406 411 PF00397 0.821
DOC_WW_Pin1_4 420 425 PF00397 0.673
DOC_WW_Pin1_4 482 487 PF00397 0.814
DOC_WW_Pin1_4 547 552 PF00397 0.820
DOC_WW_Pin1_4 647 652 PF00397 0.779
DOC_WW_Pin1_4 99 104 PF00397 0.571
LIG_14-3-3_CanoR_1 304 310 PF00244 0.766
LIG_BRCT_BRCA1_1 224 228 PF00533 0.548
LIG_BRCT_BRCA1_1 239 243 PF00533 0.258
LIG_BRCT_BRCA1_1 309 313 PF00533 0.662
LIG_BRCT_BRCA1_1 6 10 PF00533 0.759
LIG_BRCT_BRCA1_1 637 641 PF00533 0.784
LIG_BRCT_BRCA1_2 309 315 PF00533 0.660
LIG_CtBP_PxDLS_1 419 423 PF00389 0.663
LIG_EVH1_1 416 420 PF00568 0.764
LIG_FHA_1 11 17 PF00498 0.689
LIG_FHA_1 257 263 PF00498 0.649
LIG_FHA_1 407 413 PF00498 0.819
LIG_FHA_1 52 58 PF00498 0.623
LIG_FHA_1 548 554 PF00498 0.774
LIG_FHA_2 117 123 PF00498 0.614
LIG_FHA_2 127 133 PF00498 0.512
LIG_FHA_2 137 143 PF00498 0.422
LIG_FHA_2 147 153 PF00498 0.468
LIG_FHA_2 157 163 PF00498 0.453
LIG_FHA_2 167 173 PF00498 0.497
LIG_FHA_2 177 183 PF00498 0.458
LIG_FHA_2 187 193 PF00498 0.488
LIG_FHA_2 197 203 PF00498 0.495
LIG_FHA_2 207 213 PF00498 0.453
LIG_GBD_Chelix_1 23 31 PF00786 0.345
LIG_IBAR_NPY_1 677 679 PF08397 0.722
LIG_IRF3_LxIS_1 14 19 PF10401 0.462
LIG_LIR_Apic_2 296 302 PF02991 0.723
LIG_LIR_Apic_2 638 644 PF02991 0.782
LIG_LIR_Nem_3 240 246 PF02991 0.338
LIG_MYND_1 420 424 PF01753 0.829
LIG_MYND_1 540 544 PF01753 0.837
LIG_NRBOX 26 32 PF00104 0.520
LIG_PALB2_WD40_1 468 476 PF16756 0.773
LIG_Pex14_1 295 299 PF04695 0.731
LIG_Pex14_2 309 313 PF04695 0.662
LIG_PTB_Apo_2 354 361 PF02174 0.830
LIG_PTB_Phospho_1 354 360 PF10480 0.832
LIG_SH2_STAP1 572 576 PF00017 0.732
LIG_SH2_STAT3 572 575 PF00017 0.792
LIG_SH2_STAT3 643 646 PF00017 0.745
LIG_SH2_STAT3 656 659 PF00017 0.711
LIG_SH2_STAT5 360 363 PF00017 0.831
LIG_SH2_STAT5 478 481 PF00017 0.686
LIG_SH2_STAT5 598 601 PF00017 0.710
LIG_SH3_1 545 551 PF00018 0.724
LIG_SH3_3 404 410 PF00018 0.796
LIG_SH3_3 414 420 PF00018 0.737
LIG_SH3_3 509 515 PF00018 0.731
LIG_SH3_3 545 551 PF00018 0.826
LIG_SH3_3 590 596 PF00018 0.741
LIG_SH3_3 597 603 PF00018 0.735
LIG_SH3_4 301 308 PF00018 0.657
LIG_SUMO_SIM_anti_2 250 256 PF11976 0.429
LIG_SUMO_SIM_par_1 13 19 PF11976 0.504
LIG_SUMO_SIM_par_1 28 34 PF11976 0.455
LIG_SUMO_SIM_par_1 328 334 PF11976 0.739
LIG_TRAF2_1 271 274 PF00917 0.751
LIG_TRAF2_1 452 455 PF00917 0.789
LIG_UBA3_1 383 392 PF00899 0.709
LIG_WRC_WIRS_1 306 311 PF05994 0.656
LIG_WRC_WIRS_1 352 357 PF05994 0.603
LIG_WW_1 595 598 PF00397 0.675
MOD_CDC14_SPxK_1 337 340 PF00782 0.733
MOD_CDK_SPK_2 334 339 PF00069 0.824
MOD_CDK_SPK_2 420 425 PF00069 0.574
MOD_CDK_SPxK_1 334 340 PF00069 0.739
MOD_CK1_1 102 108 PF00069 0.734
MOD_CK1_1 110 116 PF00069 0.603
MOD_CK1_1 223 229 PF00069 0.682
MOD_CK1_1 293 299 PF00069 0.777
MOD_CK1_1 334 340 PF00069 0.737
MOD_CK1_1 423 429 PF00069 0.559
MOD_CK1_1 521 527 PF00069 0.687
MOD_CK1_1 579 585 PF00069 0.742
MOD_CK1_1 58 64 PF00069 0.662
MOD_CK1_1 629 635 PF00069 0.792
MOD_CK1_1 637 643 PF00069 0.729
MOD_CK1_1 670 676 PF00069 0.810
MOD_CK1_1 95 101 PF00069 0.807
MOD_CK2_1 116 122 PF00069 0.780
MOD_CK2_1 126 132 PF00069 0.639
MOD_CK2_1 136 142 PF00069 0.513
MOD_CK2_1 146 152 PF00069 0.578
MOD_CK2_1 156 162 PF00069 0.556
MOD_CK2_1 166 172 PF00069 0.590
MOD_CK2_1 176 182 PF00069 0.592
MOD_CK2_1 186 192 PF00069 0.577
MOD_CK2_1 196 202 PF00069 0.622
MOD_CK2_1 206 212 PF00069 0.552
MOD_CK2_1 449 455 PF00069 0.750
MOD_CK2_1 45 51 PF00069 0.574
MOD_CK2_1 487 493 PF00069 0.727
MOD_GlcNHglycan 228 231 PF01048 0.635
MOD_GlcNHglycan 249 252 PF01048 0.364
MOD_GlcNHglycan 319 322 PF01048 0.662
MOD_GlcNHglycan 33 36 PF01048 0.433
MOD_GlcNHglycan 333 336 PF01048 0.699
MOD_GlcNHglycan 451 454 PF01048 0.766
MOD_GlcNHglycan 497 501 PF01048 0.618
MOD_GlcNHglycan 520 523 PF01048 0.653
MOD_GlcNHglycan 578 581 PF01048 0.698
MOD_GlcNHglycan 588 591 PF01048 0.581
MOD_GlcNHglycan 99 102 PF01048 0.745
MOD_GSK3_1 101 108 PF00069 0.714
MOD_GSK3_1 109 116 PF00069 0.583
MOD_GSK3_1 118 125 PF00069 0.603
MOD_GSK3_1 128 135 PF00069 0.549
MOD_GSK3_1 138 145 PF00069 0.581
MOD_GSK3_1 148 155 PF00069 0.587
MOD_GSK3_1 158 165 PF00069 0.594
MOD_GSK3_1 168 175 PF00069 0.568
MOD_GSK3_1 178 185 PF00069 0.573
MOD_GSK3_1 188 195 PF00069 0.614
MOD_GSK3_1 198 205 PF00069 0.600
MOD_GSK3_1 208 215 PF00069 0.574
MOD_GSK3_1 218 225 PF00069 0.549
MOD_GSK3_1 289 296 PF00069 0.787
MOD_GSK3_1 482 489 PF00069 0.790
MOD_GSK3_1 51 58 PF00069 0.798
MOD_GSK3_1 582 589 PF00069 0.660
MOD_GSK3_1 93 100 PF00069 0.804
MOD_N-GLC_1 586 591 PF02516 0.641
MOD_NEK2_1 16 21 PF00069 0.360
MOD_NEK2_1 247 252 PF00069 0.339
MOD_NEK2_1 256 261 PF00069 0.447
MOD_NEK2_1 31 36 PF00069 0.367
MOD_NEK2_1 438 443 PF00069 0.549
MOD_NEK2_1 617 622 PF00069 0.574
MOD_PIKK_1 266 272 PF00454 0.582
MOD_PIKK_1 290 296 PF00454 0.720
MOD_PIKK_1 555 561 PF00454 0.815
MOD_PIKK_1 579 585 PF00454 0.652
MOD_PIKK_1 642 648 PF00454 0.823
MOD_PIKK_1 667 673 PF00454 0.721
MOD_PKA_1 266 272 PF00069 0.582
MOD_PKA_2 265 271 PF00069 0.569
MOD_PKA_2 504 510 PF00069 0.747
MOD_PKA_2 629 635 PF00069 0.652
MOD_PKA_2 673 679 PF00069 0.716
MOD_Plk_1 486 492 PF00069 0.631
MOD_Plk_1 58 64 PF00069 0.574
MOD_Plk_1 586 592 PF00069 0.554
MOD_Plk_2-3 487 493 PF00069 0.683
MOD_Plk_4 658 664 PF00069 0.803
MOD_Plk_4 70 76 PF00069 0.668
MOD_ProDKin_1 10 16 PF00069 0.536
MOD_ProDKin_1 220 226 PF00069 0.750
MOD_ProDKin_1 334 340 PF00069 0.826
MOD_ProDKin_1 406 412 PF00069 0.789
MOD_ProDKin_1 420 426 PF00069 0.581
MOD_ProDKin_1 482 488 PF00069 0.784
MOD_ProDKin_1 547 553 PF00069 0.789
MOD_ProDKin_1 647 653 PF00069 0.733
MOD_ProDKin_1 99 105 PF00069 0.721
MOD_SUMO_for_1 285 288 PF00179 0.696
MOD_SUMO_rev_2 281 287 PF00179 0.694
TRG_DiLeu_BaEn_4 274 280 PF01217 0.621
TRG_DiLeu_BaLyEn_6 258 263 PF01217 0.470
TRG_ER_diArg_1 444 446 PF00400 0.666
TRG_ER_diArg_1 62 65 PF00400 0.664

Homologs

Protein Taxonomy Sequence identity Coverage
A4HJQ5 Leishmania braziliensis 58% 100%
A4I771 Leishmania infantum 97% 100%
E9B266 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 94%
Q4Q5Z4 Leishmania major 89% 81%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS