Metalloprotease M41 FtsH, putative

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Metalloprotease M41 FtsH, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IFG3_LEIDO

TriTrypDb:

LdBPK_321570.1 , LdCL_320021400 , LDHU3_32.1990

Length:

716

Annotations

LeishMANIAdb annotations

Homologous to bacterial FtsH and Eukaryotic AFG3 proteins. Probably involved in mitochondrial protein processing.. Localization: Mitochondrial (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 31
NetGPI	no	yes: 0, no: 31

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	24
GO:0110165	cellular anatomical entity	1	25
GO:0005739	mitochondrion	5	1
GO:0005745	m-AAA complex	4	3
GO:0032991	protein-containing complex	1	3
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0098796	membrane protein complex	2	3
GO:0098798	mitochondrial protein-containing complex	2	3
GO:0098800	inner mitochondrial membrane protein complex	3	3
GO:1902494	catalytic complex	2	3
GO:1905368	peptidase complex	3	3

Expansion

Sequence features

A0A3Q8IFG3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFG3

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	32
GO:0006807	nitrogen compound metabolic process	2	32
GO:0008152	metabolic process	1	32
GO:0019538	protein metabolic process	3	32
GO:0043170	macromolecule metabolic process	3	32
GO:0044238	primary metabolic process	2	32
GO:0071704	organic substance metabolic process	2	32
GO:1901564	organonitrogen compound metabolic process	3	32
GO:0009987	cellular process	1	3
GO:0016043	cellular component organization	3	3
GO:0016485	protein processing	5	3
GO:0022607	cellular component assembly	4	3
GO:0034982	mitochondrial protein processing	6	3
GO:0043933	protein-containing complex organization	4	3
GO:0051604	protein maturation	4	3
GO:0065003	protein-containing complex assembly	5	3
GO:0071840	cellular component organization or biogenesis	2	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	32
GO:0003824	catalytic activity	1	32
GO:0004175	endopeptidase activity	4	32
GO:0004176	ATP-dependent peptidase activity	2	32
GO:0004222	metalloendopeptidase activity	5	32
GO:0005488	binding	1	32
GO:0005524	ATP binding	5	32
GO:0008233	peptidase activity	3	32
GO:0008237	metallopeptidase activity	4	32
GO:0016462	pyrophosphatase activity	5	32
GO:0016787	hydrolase activity	2	32
GO:0016817	hydrolase activity, acting on acid anhydrides	3	32
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	32
GO:0016887	ATP hydrolysis activity	7	32
GO:0017076	purine nucleotide binding	4	32
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	32
GO:0030554	adenyl nucleotide binding	5	32
GO:0032553	ribonucleotide binding	3	32
GO:0032555	purine ribonucleotide binding	4	32
GO:0032559	adenyl ribonucleotide binding	5	32
GO:0035639	purine ribonucleoside triphosphate binding	4	32
GO:0036094	small molecule binding	2	32
GO:0043167	ion binding	2	32
GO:0043168	anion binding	3	32
GO:0097159	organic cyclic compound binding	2	32
GO:0097367	carbohydrate derivative binding	2	32
GO:0140096	catalytic activity, acting on a protein	2	32
GO:0140657	ATP-dependent activity	1	32
GO:1901265	nucleoside phosphate binding	3	32
GO:1901363	heterocyclic compound binding	2	32

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	308	312	PF00656	0.443
CLV_C14_Caspase3-7	50	54	PF00656	0.399
CLV_C14_Caspase3-7	642	646	PF00656	0.497
CLV_NRD_NRD_1	154	156	PF00675	0.338
CLV_NRD_NRD_1	374	376	PF00675	0.243
CLV_PCSK_KEX2_1	154	156	PF00082	0.338
CLV_PCSK_KEX2_1	288	290	PF00082	0.243
CLV_PCSK_PC1ET2_1	288	290	PF00082	0.241
CLV_PCSK_SKI1_1	255	259	PF00082	0.242
CLV_PCSK_SKI1_1	291	295	PF00082	0.239
CLV_PCSK_SKI1_1	365	369	PF00082	0.239
CLV_PCSK_SKI1_1	375	379	PF00082	0.239
CLV_PCSK_SKI1_1	397	401	PF00082	0.268
CLV_PCSK_SKI1_1	439	443	PF00082	0.383
CLV_PCSK_SKI1_1	623	627	PF00082	0.283
CLV_PCSK_SKI1_1	677	681	PF00082	0.266
CLV_PCSK_SKI1_1	711	715	PF00082	0.361
DEG_Nend_UBRbox_3	1	3	PF02207	0.488
DOC_CYCLIN_RxL_1	288	296	PF00134	0.460
DOC_CYCLIN_RxL_1	674	684	PF00134	0.507
DOC_CYCLIN_yCln2_LP_2	228	234	PF00134	0.579
DOC_MAPK_gen_1	298	306	PF00069	0.499
DOC_MAPK_gen_1	369	379	PF00069	0.440
DOC_MAPK_gen_1	685	694	PF00069	0.439
DOC_MAPK_MEF2A_6	298	306	PF00069	0.441
DOC_MAPK_MEF2A_6	372	381	PF00069	0.441
DOC_MAPK_MEF2A_6	500	507	PF00069	0.603
DOC_MAPK_MEF2A_6	551	558	PF00069	0.389
DOC_MAPK_NFAT4_5	551	559	PF00069	0.527
DOC_PP2B_LxvP_1	38	41	PF13499	0.416
DOC_PP4_FxxP_1	146	149	PF00568	0.245
DOC_PP4_MxPP_1	26	29	PF00568	0.384
DOC_USP7_MATH_1	160	164	PF00917	0.647
DOC_USP7_MATH_1	177	181	PF00917	0.659
DOC_USP7_MATH_1	312	316	PF00917	0.451
DOC_USP7_MATH_1	420	424	PF00917	0.711
DOC_USP7_MATH_1	428	432	PF00917	0.705
DOC_USP7_MATH_1	433	437	PF00917	0.706
DOC_USP7_MATH_1	46	50	PF00917	0.595
DOC_USP7_MATH_1	461	465	PF00917	0.520
DOC_USP7_MATH_1	8	12	PF00917	0.384
DOC_USP7_UBL2_3	218	222	PF12436	0.507
DOC_USP7_UBL2_3	229	233	PF12436	0.505
DOC_USP7_UBL2_3	551	555	PF12436	0.408
DOC_USP7_UBL2_3	639	643	PF12436	0.475
DOC_USP7_UBL2_3	697	701	PF12436	0.430
DOC_WW_Pin1_4	265	270	PF00397	0.475
DOC_WW_Pin1_4	4	9	PF00397	0.548
DOC_WW_Pin1_4	426	431	PF00397	0.728
DOC_WW_Pin1_4	473	478	PF00397	0.510
LIG_14-3-3_CanoR_1	647	653	PF00244	0.483
LIG_BIR_III_2	451	455	PF00653	0.686
LIG_BIR_III_2	5	9	PF00653	0.373
LIG_BIR_III_4	311	315	PF00653	0.443
LIG_CaM_IQ_9	610	625	PF13499	0.433
LIG_FHA_1	442	448	PF00498	0.712
LIG_FHA_1	474	480	PF00498	0.504
LIG_FHA_1	544	550	PF00498	0.488
LIG_FHA_1	566	572	PF00498	0.414
LIG_FHA_2	205	211	PF00498	0.497
LIG_FHA_2	344	350	PF00498	0.468
LIG_FHA_2	412	418	PF00498	0.618
LIG_FHA_2	649	655	PF00498	0.485
LIG_IBAR_NPY_1	58	60	PF08397	0.382
LIG_LIR_Apic_2	134	138	PF02991	0.314
LIG_LIR_Gen_1	11	19	PF02991	0.423
LIG_LIR_Gen_1	277	282	PF02991	0.443
LIG_LIR_Gen_1	467	472	PF02991	0.623
LIG_LIR_Gen_1	533	543	PF02991	0.444
LIG_LIR_Gen_1	582	592	PF02991	0.477
LIG_LIR_Nem_3	111	117	PF02991	0.423
LIG_LIR_Nem_3	206	211	PF02991	0.513
LIG_LIR_Nem_3	277	281	PF02991	0.443
LIG_LIR_Nem_3	389	394	PF02991	0.489
LIG_LIR_Nem_3	467	471	PF02991	0.627
LIG_LIR_Nem_3	533	538	PF02991	0.437
LIG_LIR_Nem_3	582	588	PF02991	0.472
LIG_LIR_Nem_3	73	77	PF02991	0.368
LIG_MYND_1	42	46	PF01753	0.365
LIG_NRBOX	688	694	PF00104	0.444
LIG_PCNA_yPIPBox_3	509	522	PF02747	0.522
LIG_PDZ_Class_2	711	716	PF00595	0.636
LIG_Pex14_2	278	282	PF04695	0.433
LIG_PTB_Apo_2	139	146	PF02174	0.410
LIG_PTB_Apo_2	462	469	PF02174	0.517
LIG_PTB_Phospho_1	462	468	PF10480	0.522
LIG_SH2_CRK	104	108	PF00017	0.463
LIG_SH2_CRK	468	472	PF00017	0.457
LIG_SH2_CRK	60	64	PF00017	0.540
LIG_SH2_CRK	77	81	PF00017	0.375
LIG_SH2_GRB2like	394	397	PF00017	0.507
LIG_SH2_SRC	104	107	PF00017	0.488
LIG_SH2_STAP1	468	472	PF00017	0.509
LIG_SH2_STAP1	567	571	PF00017	0.453
LIG_SH2_STAP1	89	93	PF00017	0.397
LIG_SH2_STAT3	17	20	PF00017	0.413
LIG_SH2_STAT3	32	35	PF00017	0.347
LIG_SH2_STAT3	567	570	PF00017	0.433
LIG_SH2_STAT3	79	82	PF00017	0.461
LIG_SH2_STAT3	91	94	PF00017	0.540
LIG_SH2_STAT5	152	155	PF00017	0.348
LIG_SH2_STAT5	224	227	PF00017	0.492
LIG_SH2_STAT5	394	397	PF00017	0.493
LIG_SH2_STAT5	567	570	PF00017	0.446
LIG_SH2_STAT5	60	63	PF00017	0.483
LIG_SH2_STAT5	672	675	PF00017	0.463
LIG_SH2_STAT5	91	94	PF00017	0.463
LIG_SH3_3	100	106	PF00018	0.471
LIG_SH3_3	118	124	PF00018	0.347
LIG_SH3_3	190	196	PF00018	0.625
LIG_SH3_3	374	380	PF00018	0.433
LIG_SH3_4	406	413	PF00018	0.579
LIG_SH3_4	639	646	PF00018	0.527
LIG_Sin3_3	664	671	PF02671	0.393
LIG_SUMO_SIM_anti_2	349	355	PF11976	0.447
LIG_SxIP_EBH_1	555	565	PF03271	0.425
LIG_TRAF2_1	217	220	PF00917	0.479
LIG_TRAF2_1	328	331	PF00917	0.456
LIG_TRAF2_2	107	112	PF00917	0.422
LIG_TYR_ITSM	531	538	PF00017	0.295
LIG_UBA3_1	187	195	PF00899	0.497
MOD_CK1_1	131	137	PF00069	0.410
MOD_CK1_1	473	479	PF00069	0.421
MOD_CK1_1	526	532	PF00069	0.304
MOD_CK2_1	325	331	PF00069	0.305
MOD_CK2_1	343	349	PF00069	0.259
MOD_CK2_1	411	417	PF00069	0.535
MOD_CK2_1	461	467	PF00069	0.435
MOD_CK2_1	648	654	PF00069	0.343
MOD_CMANNOS	649	652	PF00535	0.410
MOD_Cter_Amidation	517	520	PF01082	0.434
MOD_Cter_Amidation	694	697	PF01082	0.464
MOD_GlcNHglycan	124	127	PF01048	0.503
MOD_GlcNHglycan	130	133	PF01048	0.467
MOD_GlcNHglycan	162	165	PF01048	0.571
MOD_GlcNHglycan	17	20	PF01048	0.640
MOD_GlcNHglycan	170	173	PF01048	0.666
MOD_GlcNHglycan	184	187	PF01048	0.570
MOD_GlcNHglycan	273	276	PF01048	0.278
MOD_GlcNHglycan	284	287	PF01048	0.316
MOD_GlcNHglycan	422	425	PF01048	0.719
MOD_GlcNHglycan	430	433	PF01048	0.720
MOD_GlcNHglycan	669	672	PF01048	0.314
MOD_GSK3_1	160	167	PF00069	0.577
MOD_GSK3_1	178	185	PF00069	0.553
MOD_GSK3_1	265	272	PF00069	0.274
MOD_GSK3_1	4	11	PF00069	0.493
MOD_GSK3_1	473	480	PF00069	0.378
MOD_GSK3_1	526	533	PF00069	0.295
MOD_N-GLC_1	331	336	PF02516	0.297
MOD_N-GLC_1	526	531	PF02516	0.203
MOD_NEK2_1	271	276	PF00069	0.212
MOD_NEK2_1	282	287	PF00069	0.228
MOD_NEK2_1	530	535	PF00069	0.275
MOD_NEK2_1	543	548	PF00069	0.323
MOD_NEK2_1	583	588	PF00069	0.283
MOD_NEK2_1	629	634	PF00069	0.304
MOD_NEK2_1	667	672	PF00069	0.257
MOD_NEK2_2	8	13	PF00069	0.608
MOD_PIKK_1	47	53	PF00454	0.524
MOD_PIKK_1	565	571	PF00454	0.293
MOD_PIKK_1	583	589	PF00454	0.293
MOD_PIKK_1	78	84	PF00454	0.544
MOD_PK_1	453	459	PF00069	0.402
MOD_PK_1	603	609	PF00069	0.403
MOD_PKA_1	375	381	PF00069	0.203
MOD_PKA_2	122	128	PF00069	0.523
MOD_PKA_2	523	529	PF00069	0.310
MOD_PKA_2	614	620	PF00069	0.296
MOD_Plk_1	331	337	PF00069	0.293
MOD_Plk_1	526	532	PF00069	0.282
MOD_Plk_1	603	609	PF00069	0.318
MOD_Plk_1	675	681	PF00069	0.369
MOD_Plk_2-3	577	583	PF00069	0.410
MOD_Plk_4	131	137	PF00069	0.281
MOD_Plk_4	253	259	PF00069	0.290
MOD_Plk_4	483	489	PF00069	0.364
MOD_Plk_4	554	560	PF00069	0.289
MOD_Plk_4	675	681	PF00069	0.321
MOD_Plk_4	703	709	PF00069	0.287
MOD_Plk_4	8	14	PF00069	0.564
MOD_ProDKin_1	265	271	PF00069	0.338
MOD_ProDKin_1	4	10	PF00069	0.713
MOD_ProDKin_1	426	432	PF00069	0.693
MOD_ProDKin_1	473	479	PF00069	0.384
MOD_SUMO_for_1	217	220	PF00179	0.447
MOD_SUMO_for_1	452	455	PF00179	0.622
MOD_SUMO_for_1	658	661	PF00179	0.314
MOD_SUMO_rev_2	292	300	PF00179	0.410
MOD_SUMO_rev_2	370	378	PF00179	0.288
MOD_SUMO_rev_2	437	447	PF00179	0.706
MOD_SUMO_rev_2	450	454	PF00179	0.430
TRG_DiLeu_BaEn_1	443	448	PF01217	0.675
TRG_DiLeu_BaEn_1	663	668	PF01217	0.298
TRG_ENDOCYTIC_2	114	117	PF00928	0.506
TRG_ENDOCYTIC_2	224	227	PF00928	0.362
TRG_ENDOCYTIC_2	468	471	PF00928	0.544
TRG_ENDOCYTIC_2	535	538	PF00928	0.285
TRG_ER_diArg_1	153	155	PF00400	0.428
TRG_ER_diArg_1	522	525	PF00400	0.470
TRG_ER_diArg_1	560	563	PF00400	0.279
TRG_Pf-PMV_PEXEL_1	291	295	PF00026	0.292
TRG_Pf-PMV_PEXEL_1	333	337	PF00026	0.318
TRG_Pf-PMV_PEXEL_1	665	669	PF00026	0.323

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8A5	Leptomonas seymouri	47%	100%
A0A0N1HUW7	Leptomonas seymouri	32%	100%
A0A0N1I6C1	Leptomonas seymouri	34%	92%
A0A0N1IMN9	Leptomonas seymouri	78%	100%
A0A0N1PBB9	Leptomonas seymouri	47%	100%
A0A0N1PGD9	Leptomonas seymouri	32%	72%
A0A0S4J3N2	Bodo saltans	71%	100%
A0A0S4J9Q2	Bodo saltans	35%	100%
A0A0S4JAH0	Bodo saltans	49%	100%
A0A0S4JGG9	Bodo saltans	50%	100%
A0A0S4JTL4	Bodo saltans	33%	85%
A0A0S4KHE9	Bodo saltans	35%	89%
A0A1X0NKD8	Trypanosomatidae	33%	100%
A0A1X0NW32	Trypanosomatidae	76%	100%
A0A1X0P749	Trypanosomatidae	51%	100%
A0A1X0P7E6	Trypanosomatidae	51%	100%
A0A1X0P9F5	Trypanosomatidae	34%	99%
A0A3Q8IHD0	Leishmania donovani	34%	100%
A0A3Q8IJP7	Leishmania donovani	48%	100%
A0A3R7KKD0	Trypanosoma rangeli	47%	100%
A0A3R7L0P7	Trypanosoma rangeli	75%	100%
A0A3S5H775	Leishmania donovani	47%	100%
A0A3S5H828	Leishmania donovani	32%	100%
A0A422N673	Trypanosoma rangeli	36%	100%
A0A422NJ44	Trypanosoma rangeli	51%	100%
A0LN68	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)	35%	100%
A0LR74	Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B)	34%	100%
A0PXM8	Clostridium novyi (strain NT)	39%	100%
A1URA3	Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583)	33%	94%
A2ZVG7	Oryza sativa subsp. japonica	35%	91%
A4H9H1	Leishmania braziliensis	53%	100%
A4HAA8	Leishmania braziliensis	47%	98%
A4HAL9	Leishmania braziliensis	35%	91%
A4HJ48	Leishmania braziliensis	31%	70%
A4HKD8	Leishmania braziliensis	86%	99%
A4HPD5	Leishmania braziliensis	33%	100%
A4HXT7	Leishmania infantum	52%	100%
A4HYI8	Leishmania infantum	47%	99%
A4I809	Leishmania infantum	100%	100%
A4I9Q6	Leishmania infantum	34%	100%
A4ICH8	Leishmania infantum	33%	100%
A5U8T5	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	34%	94%
A5W382	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	36%	100%
A6LD25	Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)	32%	100%
A6QBN8	Sulfurovum sp. (strain NBC37-1)	33%	100%
A6TSZ1	Alkaliphilus metalliredigens (strain QYMF)	33%	100%
A6TWP7	Alkaliphilus metalliredigens (strain QYMF)	37%	100%
A8F7F7	Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)	39%	100%
A8ZNZ4	Acaryochloris marina (strain MBIC 11017)	36%	100%
A9BFL9	Petrotoga mobilis (strain DSM 10674 / SJ95)	32%	100%
A9BHD3	Petrotoga mobilis (strain DSM 10674 / SJ95)	32%	100%
A9EXK6	Sorangium cellulosum (strain So ce56)	32%	100%
A9NE17	Acholeplasma laidlawii (strain PG-8A)	36%	100%
B0B970	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	36%	78%
B0K5A3	Thermoanaerobacter sp. (strain X514)	36%	100%
B0K657	Thermoanaerobacter sp. (strain X514)	34%	100%
B1AI94	Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736)	32%	99%
B1ZMG6	Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)	34%	100%
B2JVU2	Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)	36%	100%
B2UE66	Ralstonia pickettii (strain 12J)	36%	100%
B2UMY1	Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)	34%	88%
B3DY14	Methylacidiphilum infernorum (isolate V4)	35%	100%
B3PNH3	Metamycoplasma arthritidis (strain 158L3-1)	35%	96%
B3QZS3	Phytoplasma mali (strain AT)	32%	100%
B3R057	Phytoplasma mali (strain AT)	34%	100%
B3R0R7	Phytoplasma mali (strain AT)	33%	100%
B4SCV5	Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)	35%	100%
B4U7U4	Hydrogenobaculum sp. (strain Y04AAS1)	34%	100%
B7J0N5	Borreliella burgdorferi (strain ZS7)	34%	100%
B7T1V0	Vaucheria litorea	33%	100%
B8D065	Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)	35%	100%
B8G4Q6	Chloroflexus aggregans (strain MD-66 / DSM 9485)	32%	100%
B8H444	Caulobacter vibrioides (strain NA1000 / CB15N)	34%	100%
B8I4B9	Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)	35%	100%
B8J992	Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)	35%	100%
B9L3S8	Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)	37%	100%
B9MPK5	Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320)	36%	100%
C0ZPK5	Rhodococcus erythropolis (strain PR4 / NBRC 100887)	35%	84%
C1F8X6	Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)	37%	100%
C5CES8	Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1)	34%	100%
C5J6A7	Mesomycoplasma conjunctivae (strain ATCC 25834 / NCTC 10147 / HRC/581)	33%	95%
C6V4R9	Neorickettsia risticii (strain Illinois)	33%	100%
C6VKW6	Lactiplantibacillus plantarum (strain JDM1)	38%	96%
C7M0M0	Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)	35%	100%
C7MC16	Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 / NCIMB 9860 / 6-10)	33%	100%
C7N1I1	Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1)	35%	91%
C7N914	Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b)	35%	93%
C8W731	Lancefieldella parvula (strain ATCC 33793 / DSM 20469 / CCUG 32760 / JCM 10300 / KCTC 3663 / VPI 0546 / 1246)	32%	100%
C8WEG0	Zymomonas mobilis subsp. mobilis (strain NCIMB 11163 / B70)	36%	100%
C9ZMX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZZX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
D0A3J7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0AA32	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	67%	100%
D0LWB8	Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)	36%	100%
D0MGU8	Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10)	36%	100%
D1AXT4	Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10651 / 9901)	37%	100%
D1BLD0	Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3)	38%	100%
D1C2C6	Sphaerobacter thermophilus (strain DSM 20745 / S 6022)	36%	100%
D1CDT8	Thermobaculum terrenum (strain ATCC BAA-798 / YNP1)	37%	100%
D2NQQ7	Rothia mucilaginosa (strain DY-18)	37%	95%
D2QZ34	Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128)	35%	100%
D3EZK2	Conexibacter woesei (strain DSM 14684 / CIP 108061 / JCM 11494 / NBRC 100937 / ID131577)	38%	96%
D3FFN2	Mycoplasma gallisepticum (strain R(high / passage 156))	33%	94%
D4HA34	Cutibacterium acnes (strain SK137)	37%	100%
D5D8E3	Sulcia muelleri (strain DMIN)	35%	100%
D5H7Z5	Salinibacter ruber (strain M8)	35%	100%
D5HA94	Salinibacter ruber (strain M8)	33%	100%
E9ARJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	100%
E9ASB2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	99%
E9B1M1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	81%
E9B2S6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B4S8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
O19922	Cyanidium caldarium	35%	100%
O32617	Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)	34%	100%
O69076	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	37%	100%
O78516	Guillardia theta	33%	100%
O80983	Arabidopsis thaliana	36%	100%
O82150	Nicotiana tabacum	37%	100%
P0A4V9	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	34%	94%
P0AAI3	Escherichia coli (strain K12)	33%	100%
P0AAI4	Shigella flexneri	33%	100%
P32795	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	96%
P37476	Bacillus subtilis (strain 168)	34%	100%
P39925	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	94%
P40341	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	87%
P46469	Lactococcus lactis subsp. lactis (strain IL1403)	34%	100%
P47695	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	33%	100%
P49825	Trieres chinensis	31%	100%
P51327	Porphyra purpurea	34%	100%
P57462	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	32%	100%
P59652	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	37%	100%
P63343	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	33%	100%
P63344	Salmonella typhi	33%	100%
P71377	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	33%	100%
P71408	Helicobacter pylori (strain ATCC 700392 / 26695)	33%	100%
P73179	Synechocystis sp. (strain PCC 6803 / Kazusa)	36%	100%
P73437	Synechocystis sp. (strain PCC 6803 / Kazusa)	34%	100%
P75120	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	34%	100%
P94304	Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)	35%	100%
P9WQN2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	34%	94%
P9WQN3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	34%	94%
Q03Z46	Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)	36%	100%
Q04Q03	Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)	35%	100%
Q0DHL4	Oryza sativa subsp. japonica	38%	87%
Q0TTK8	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	33%	100%
Q10ZF7	Trichodesmium erythraeum (strain IMS101)	37%	100%
Q1AV13	Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1)	36%	100%
Q1D491	Myxococcus xanthus (strain DK1622)	36%	100%
Q1LLA9	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)	34%	100%
Q1RGP0	Rickettsia bellii (strain RML369-C)	31%	100%
Q1XDF9	Neopyropia yezoensis	35%	100%
Q2JNP0	Synechococcus sp. (strain JA-2-3B'a(2-13))	37%	100%
Q2KJI7	Bos taurus	35%	89%
Q2NIN5	Aster yellows witches'-broom phytoplasma (strain AYWB)	36%	100%
Q2SF13	Hahella chejuensis (strain KCTC 2396)	30%	100%
Q39102	Arabidopsis thaliana	36%	100%
Q39444	Capsicum annuum	37%	100%
Q3B6R3	Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530)	36%	100%
Q3JEE4	Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107)	36%	100%
Q3JMH0	Burkholderia pseudomallei (strain 1710b)	36%	100%
Q3ULF4	Mus musculus	36%	92%
Q4A5F0	Mycoplasmopsis synoviae (strain 53)	34%	100%
Q4Q399	Leishmania major	34%	100%
Q4Q5D1	Leishmania major	97%	100%
Q4Q6J3	Leishmania major	32%	81%
Q4QD50	Leishmania major	46%	99%
Q4QDY0	Leishmania major	52%	100%
Q4UN68	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	34%	100%
Q55700	Synechocystis sp. (strain PCC 6803 / Kazusa)	34%	100%
Q5SI82	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	36%	100%
Q5Z974	Oryza sativa subsp. japonica	36%	100%
Q60AK1	Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)	33%	100%
Q655S1	Oryza sativa subsp. japonica	35%	100%
Q67JH0	Symbiobacterium thermophilum (strain T / IAM 14863)	39%	100%
Q67LC0	Symbiobacterium thermophilum (strain T / IAM 14863)	35%	100%
Q67T82	Symbiobacterium thermophilum (strain T / IAM 14863)	37%	100%
Q67WJ2	Oryza sativa subsp. japonica	35%	100%
Q68XR9	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	34%	100%
Q6KHA4	Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)	32%	100%
Q6LUJ8	Photobacterium profundum (strain SS9)	35%	100%
Q6M2F0	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	35%	84%
Q6MDI5	Protochlamydia amoebophila (strain UWE25)	38%	78%
Q6MJV1	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	35%	100%
Q6MLS7	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	34%	100%
Q7TT47	Rattus norvegicus	37%	92%
Q7URM7	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	33%	98%
Q7UUZ7	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	36%	100%
Q83FV7	Tropheryma whipplei (strain Twist)	35%	100%
Q83XX3	Oenococcus oeni	35%	100%
Q84WU8	Arabidopsis thaliana	39%	89%
Q88Z31	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	38%	96%
Q89AF2	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	32%	100%
Q8EUA6	Malacoplasma penetrans (strain HF-2)	34%	87%
Q8JZQ2	Mus musculus	35%	89%
Q8K9G8	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	32%	100%
Q8LQJ8	Oryza sativa subsp. japonica	36%	100%
Q8LQJ9	Oryza sativa subsp. japonica	37%	100%
Q8S2A7	Oryza sativa subsp. japonica	37%	89%
Q8VZI8	Arabidopsis thaliana	38%	88%
Q8W585	Arabidopsis thaliana	34%	100%
Q8X9L0	Escherichia coli O157:H7	33%	100%
Q8YMZ8	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	35%	100%
Q920A7	Mus musculus	37%	91%
Q92JJ9	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	34%	100%
Q98PE4	Mycoplasmopsis pulmonis (strain UAB CTIP)	31%	99%
Q9BAE0	Medicago sativa	36%	100%
Q9CD58	Mycobacterium leprae (strain TN)	34%	91%
Q9FH02	Arabidopsis thaliana	37%	100%
Q9HGM3	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	93%
Q9N3T5	Caenorhabditis elegans	36%	92%
Q9TJ83	Cyanidioschyzon merolae (strain NIES-3377 / 10D)	33%	100%
Q9UQ90	Homo sapiens	36%	90%
Q9WZ49	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	36%	100%
Q9Y4W6	Homo sapiens	35%	90%
Q9ZEA2	Rickettsia prowazekii (strain Madrid E)	34%	100%
Q9ZM66	Helicobacter pylori (strain J99 / ATCC 700824)	33%	100%
V5B092	Trypanosoma cruzi	35%	100%
V5B4C8	Trypanosoma cruzi	48%	100%
V5BEV9	Trypanosoma cruzi	35%	100%
V5BP04	Trypanosoma cruzi	73%	100%