Kinetoplastid kinetochore protein 3, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid kinetochore protein 3, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IFG0_LEIDO

TriTrypDb:

LdBPK_354110.1 , LdCL_350046200 , LDHU3_35.5330

Length:

1285

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0000776	kinetochore	3	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0099080	supramolecular complex	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3Q8IFG0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0007059	chromosome segregation	2	1
GO:0008152	metabolic process	1	7
GO:0008283	cell population proliferation	2	1
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0019538	protein metabolic process	3	7

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0004674	protein serine/threonine kinase activity	4	1
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1064	1068	PF00656	0.504
CLV_C14_Caspase3-7	1147	1151	PF00656	0.451
CLV_NRD_NRD_1	1053	1055	PF00675	0.536
CLV_NRD_NRD_1	1250	1252	PF00675	0.346
CLV_NRD_NRD_1	210	212	PF00675	0.389
CLV_NRD_NRD_1	289	291	PF00675	0.335
CLV_NRD_NRD_1	339	341	PF00675	0.439
CLV_NRD_NRD_1	454	456	PF00675	0.530
CLV_NRD_NRD_1	476	478	PF00675	0.611
CLV_NRD_NRD_1	482	484	PF00675	0.625

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4X3	Leptomonas seymouri	62%	93%
A4HN76	Leishmania braziliensis	79%	99%
A4IBU4	Leishmania infantum	100%	100%
E9AFN1	Leishmania major	91%	99%
E9B6T4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%

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