Shwachman-Bodian-Diamond syndrome (SBDS) protein/SBDS protein C-terminal domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Shwachman-Bodian-Diamond syndrome (SBDS) protein/SBDS protein C-terminal domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IFC9_LEIDO

TriTrypDb:

LdBPK_341190.1 , LdCL_340017800 , LDHU3_34.1910

Length:

535

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IFC9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IFC9

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	7
GO:0022613	ribonucleoprotein complex biogenesis	4	7
GO:0042254	ribosome biogenesis	5	7
GO:0044085	cellular component biogenesis	3	7
GO:0071840	cellular component organization or biogenesis	2	7

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	259	263	PF00656	0.662
CLV_C14_Caspase3-7	370	374	PF00656	0.820
CLV_C14_Caspase3-7	455	459	PF00656	0.619
CLV_NRD_NRD_1	12	14	PF00675	0.600
CLV_NRD_NRD_1	292	294	PF00675	0.845
CLV_NRD_NRD_1	355	357	PF00675	0.779
CLV_NRD_NRD_1	422	424	PF00675	0.696
CLV_NRD_NRD_1	442	444	PF00675	0.805
CLV_NRD_NRD_1	464	466	PF00675	0.808
CLV_NRD_NRD_1	497	499	PF00675	0.680
CLV_PCSK_FUR_1	420	424	PF00082	0.635
CLV_PCSK_KEX2_1	12	14	PF00082	0.600
CLV_PCSK_KEX2_1	292	294	PF00082	0.855
CLV_PCSK_KEX2_1	355	357	PF00082	0.662
CLV_PCSK_KEX2_1	422	424	PF00082	0.731
CLV_PCSK_PC1ET2_1	422	424	PF00082	0.731
CLV_PCSK_SKI1_1	155	159	PF00082	0.329
CLV_PCSK_SKI1_1	241	245	PF00082	0.520
CLV_PCSK_SKI1_1	351	355	PF00082	0.591
CLV_PCSK_SKI1_1	466	470	PF00082	0.825
CLV_PCSK_SKI1_1	477	481	PF00082	0.650
CLV_PCSK_SKI1_1	88	92	PF00082	0.353
DEG_SPOP_SBC_1	297	301	PF00917	0.746
DOC_CYCLIN_yClb5_NLxxxL_5	227	236	PF00134	0.599
DOC_MAPK_gen_1	12	19	PF00069	0.560
DOC_MAPK_gen_1	154	160	PF00069	0.546
DOC_MAPK_gen_1	21	31	PF00069	0.546
DOC_MAPK_MEF2A_6	24	31	PF00069	0.546
DOC_USP7_MATH_1	139	143	PF00917	0.593
DOC_USP7_MATH_1	243	247	PF00917	0.643
DOC_USP7_MATH_1	296	300	PF00917	0.743
DOC_USP7_MATH_1	434	438	PF00917	0.752
DOC_USP7_UBL2_3	24	28	PF12436	0.591
DOC_USP7_UBL2_3	462	466	PF12436	0.834
DOC_USP7_UBL2_3	499	503	PF12436	0.706
LIG_14-3-3_CanoR_1	180	189	PF00244	0.518
LIG_BIR_II_1	1	5	PF00653	0.740
LIG_deltaCOP1_diTrp_1	516	522	PF00928	0.797
LIG_FHA_1	102	108	PF00498	0.627
LIG_FHA_2	181	187	PF00498	0.621
LIG_FHA_2	80	86	PF00498	0.619
LIG_LIR_Gen_1	56	67	PF02991	0.546
LIG_LIR_Nem_3	108	114	PF02991	0.429
LIG_LIR_Nem_3	56	62	PF02991	0.546
LIG_NRBOX	159	165	PF00104	0.619
LIG_SH2_STAT3	435	438	PF00017	0.719
LIG_SH2_STAT5	66	69	PF00017	0.619
LIG_SH3_3	127	133	PF00018	0.563
LIG_SUMO_SIM_anti_2	113	119	PF11976	0.546
LIG_SUMO_SIM_anti_2	15	21	PF11976	0.411
LIG_TRAF2_1	490	493	PF00917	0.789
LIG_TRAF2_1	99	102	PF00917	0.546
LIG_UBA3_1	232	241	PF00899	0.514
MOD_CK1_1	246	252	PF00069	0.616
MOD_CK1_1	299	305	PF00069	0.774
MOD_CK1_1	40	46	PF00069	0.619
MOD_CK1_1	79	85	PF00069	0.466
MOD_CK2_1	180	186	PF00069	0.618
MOD_CK2_1	335	341	PF00069	0.843
MOD_CK2_1	40	46	PF00069	0.619
MOD_CK2_1	487	493	PF00069	0.690
MOD_CK2_1	66	72	PF00069	0.546
MOD_CK2_1	79	85	PF00069	0.546
MOD_Cter_Amidation	420	423	PF01082	0.759
MOD_Cter_Amidation	441	444	PF01082	0.770
MOD_Cter_Amidation	460	463	PF01082	0.811
MOD_GlcNHglycan	1	4	PF01048	0.743
MOD_GlcNHglycan	166	169	PF01048	0.266
MOD_GlcNHglycan	212	215	PF01048	0.712
MOD_GlcNHglycan	245	248	PF01048	0.662
MOD_GlcNHglycan	301	304	PF01048	0.792
MOD_GlcNHglycan	306	309	PF01048	0.713
MOD_GlcNHglycan	332	335	PF01048	0.642
MOD_GlcNHglycan	373	376	PF01048	0.689
MOD_GlcNHglycan	42	45	PF01048	0.419
MOD_GlcNHglycan	427	430	PF01048	0.840
MOD_GSK3_1	202	209	PF00069	0.613
MOD_GSK3_1	284	291	PF00069	0.747
MOD_GSK3_1	304	311	PF00069	0.705
MOD_GSK3_1	315	322	PF00069	0.695
MOD_GSK3_1	40	47	PF00069	0.466
MOD_GSK3_1	72	79	PF00069	0.466
MOD_N-GLC_1	329	334	PF02516	0.841
MOD_N-GLC_1	363	368	PF02516	0.759
MOD_N-GLC_1	425	430	PF02516	0.839
MOD_NEK2_1	149	154	PF00069	0.551
MOD_NEK2_1	164	169	PF00069	0.537
MOD_NEK2_1	371	376	PF00069	0.690
MOD_PIKK_1	116	122	PF00454	0.541
MOD_PIKK_1	124	130	PF00454	0.562
MOD_PIKK_1	434	440	PF00454	0.834
MOD_PIKK_1	505	511	PF00454	0.580
MOD_PIKK_1	7	13	PF00454	0.606
MOD_PKA_1	12	18	PF00069	0.571
MOD_PKA_2	12	18	PF00069	0.571
MOD_PKA_2	179	185	PF00069	0.506
MOD_PKA_2	20	26	PF00069	0.546
MOD_PKA_2	345	351	PF00069	0.658
MOD_Plk_1	149	155	PF00069	0.563
MOD_Plk_4	72	78	PF00069	0.539
MOD_SUMO_for_1	27	30	PF00179	0.591
TRG_NES_CRM1_1	138	150	PF08389	0.546
TRG_NES_CRM1_1	389	400	PF08389	0.710
TRG_NLS_Bipartite_1	462	481	PF00514	0.633
TRG_NLS_MonoCore_2	421	426	PF00514	0.766
TRG_NLS_MonoExtC_3	461	466	PF00514	0.832
TRG_NLS_MonoExtC_3	476	481	PF00514	0.579
TRG_NLS_MonoExtN_4	420	427	PF00514	0.746
TRG_NLS_MonoExtN_4	460	466	PF00514	0.833

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A422NGQ3	Trypanosoma rangeli	46%	100%
A4HAM9	Leishmania braziliensis	71%	99%
A4I9S1	Leishmania infantum	99%	100%
E9B4T2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q394	Leishmania major	92%	100%