Ubiquitin-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IF70_LEIDO

TriTrypDb:

LdBPK_352650.1 , LdCL_350031400 , LDHU3_35.3400

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IF70

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IF70

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	109	111	PF00675	0.778
CLV_NRD_NRD_1	192	194	PF00675	0.827
CLV_NRD_NRD_1	210	212	PF00675	0.501
CLV_NRD_NRD_1	270	272	PF00675	0.608
CLV_NRD_NRD_1	36	38	PF00675	0.722
CLV_NRD_NRD_1	8	10	PF00675	0.749
CLV_PCSK_FUR_1	33	37	PF00082	0.706
CLV_PCSK_FUR_1	6	10	PF00082	0.750
CLV_PCSK_KEX2_1	103	105	PF00082	0.811
CLV_PCSK_KEX2_1	209	211	PF00082	0.818
CLV_PCSK_KEX2_1	269	271	PF00082	0.609
CLV_PCSK_KEX2_1	35	37	PF00082	0.774
CLV_PCSK_KEX2_1	41	43	PF00082	0.758
CLV_PCSK_KEX2_1	8	10	PF00082	0.749
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.857
CLV_PCSK_PC1ET2_1	269	271	PF00082	0.609
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.774
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.758
CLV_PCSK_PC7_1	37	43	PF00082	0.682
CLV_PCSK_SKI1_1	131	135	PF00082	0.757
CLV_PCSK_SKI1_1	142	146	PF00082	0.659
CLV_PCSK_SKI1_1	194	198	PF00082	0.639
CLV_PCSK_SKI1_1	270	274	PF00082	0.611
CLV_PCSK_SKI1_1	41	45	PF00082	0.834
CLV_PCSK_SKI1_1	93	97	PF00082	0.667
DEG_APCC_DBOX_1	269	277	PF00400	0.617
DEG_Nend_UBRbox_1	1	4	PF02207	0.807
DEG_SCF_FBW7_1	188	195	PF00400	0.709
DOC_CDC14_PxL_1	288	296	PF14671	0.564
DOC_CKS1_1	184	189	PF01111	0.706
DOC_CKS1_1	224	229	PF01111	0.768
DOC_CKS1_1	83	88	PF01111	0.775
DOC_MAPK_gen_1	269	275	PF00069	0.610
DOC_MAPK_MEF2A_6	240	247	PF00069	0.428
DOC_MAPK_MEF2A_6	269	277	PF00069	0.617
DOC_PP4_FxxP_1	322	325	PF00568	0.674
DOC_USP7_MATH_1	118	122	PF00917	0.727
DOC_USP7_MATH_1	175	179	PF00917	0.734
DOC_USP7_MATH_1	258	262	PF00917	0.623
DOC_USP7_MATH_1	68	72	PF00917	0.753
DOC_USP7_UBL2_3	138	142	PF12436	0.851
DOC_USP7_UBL2_3	35	39	PF12436	0.798
DOC_USP7_UBL2_3	57	61	PF12436	0.778
DOC_WW_Pin1_4	111	116	PF00397	0.704
DOC_WW_Pin1_4	183	188	PF00397	0.712
DOC_WW_Pin1_4	223	228	PF00397	0.763
DOC_WW_Pin1_4	281	286	PF00397	0.698
DOC_WW_Pin1_4	41	46	PF00397	0.834
DOC_WW_Pin1_4	69	74	PF00397	0.704
DOC_WW_Pin1_4	82	87	PF00397	0.730
LIG_14-3-3_CanoR_1	110	115	PF00244	0.827
LIG_14-3-3_CanoR_1	131	136	PF00244	0.698
LIG_14-3-3_CanoR_1	193	199	PF00244	0.833
LIG_14-3-3_CanoR_1	256	266	PF00244	0.538
LIG_14-3-3_CanoR_1	312	320	PF00244	0.542
LIG_14-3-3_CanoR_1	8	16	PF00244	0.665
LIG_FHA_1	193	199	PF00498	0.824
LIG_FHA_1	224	230	PF00498	0.771
LIG_FHA_1	242	248	PF00498	0.320
LIG_FHA_1	303	309	PF00498	0.631
LIG_FHA_1	85	91	PF00498	0.716
LIG_FHA_2	262	268	PF00498	0.564
LIG_Integrin_isoDGR_2	297	299	PF01839	0.680
LIG_Integrin_RGD_1	240	242	PF01839	0.484
LIG_LIR_Apic_2	317	323	PF02991	0.600
LIG_RPA_C_Fungi	204	216	PF08784	0.644
LIG_SH2_STAT5	14	17	PF00017	0.736
LIG_SH2_STAT5	28	31	PF00017	0.496
LIG_SH2_STAT5	320	323	PF00017	0.460
LIG_SH3_1	215	221	PF00018	0.714
LIG_SH3_1	80	86	PF00018	0.712
LIG_SH3_1	88	94	PF00018	0.683
LIG_SH3_2	189	194	PF14604	0.804
LIG_SH3_2	83	88	PF14604	0.841
LIG_SH3_3	181	187	PF00018	0.828
LIG_SH3_3	215	221	PF00018	0.792
LIG_SH3_3	272	278	PF00018	0.576
LIG_SH3_3	286	292	PF00018	0.511
LIG_SH3_3	45	51	PF00018	0.800
LIG_SH3_3	80	86	PF00018	0.810
LIG_SH3_3	88	94	PF00018	0.741
LIG_SUMO_SIM_anti_2	242	247	PF11976	0.561
LIG_SUMO_SIM_par_1	242	249	PF11976	0.488
MOD_CDK_SPK_2	188	193	PF00069	0.709
MOD_CDK_SPxK_1	188	194	PF00069	0.709
MOD_CDK_SPxK_1	82	88	PF00069	0.773
MOD_CK1_1	161	167	PF00069	0.721
MOD_CK1_1	261	267	PF00069	0.494
MOD_CK1_1	284	290	PF00069	0.608
MOD_CK1_1	314	320	PF00069	0.542
MOD_CK1_1	72	78	PF00069	0.713
MOD_GlcNHglycan	177	180	PF01048	0.751
MOD_GlcNHglycan	281	284	PF01048	0.737
MOD_GlcNHglycan	313	316	PF01048	0.560
MOD_GSK3_1	188	195	PF00069	0.709
MOD_GSK3_1	246	253	PF00069	0.480
MOD_GSK3_1	257	264	PF00069	0.543
MOD_GSK3_1	277	284	PF00069	0.385
MOD_GSK3_1	31	38	PF00069	0.713
MOD_GSK3_1	311	318	PF00069	0.547
MOD_GSK3_1	56	63	PF00069	0.729
MOD_GSK3_1	68	75	PF00069	0.622
MOD_GSK3_1	78	85	PF00069	0.651
MOD_GSK3_1	89	96	PF00069	0.574
MOD_N-GLC_1	250	255	PF02516	0.611
MOD_NEK2_1	246	251	PF00069	0.628
MOD_NEK2_2	315	320	PF00069	0.537
MOD_PKA_1	110	116	PF00069	0.733
MOD_PKA_1	35	41	PF00069	0.728
MOD_PKA_1	61	67	PF00069	0.676
MOD_PKA_2	109	115	PF00069	0.845
MOD_PKA_2	145	151	PF00069	0.756
MOD_PKA_2	192	198	PF00069	0.829
MOD_PKA_2	311	317	PF00069	0.550
MOD_PKA_2	35	41	PF00069	0.728
MOD_PKB_1	108	116	PF00069	0.732
MOD_PKB_1	129	137	PF00069	0.705
MOD_Plk_1	241	247	PF00069	0.612
MOD_Plk_1	261	267	PF00069	0.571
MOD_Plk_1	315	321	PF00069	0.531
MOD_Plk_4	200	206	PF00069	0.821
MOD_Plk_4	241	247	PF00069	0.499
MOD_Plk_4	261	267	PF00069	0.608
MOD_Plk_4	284	290	PF00069	0.646
MOD_Plk_4	315	321	PF00069	0.609
MOD_ProDKin_1	111	117	PF00069	0.703
MOD_ProDKin_1	183	189	PF00069	0.708
MOD_ProDKin_1	223	229	PF00069	0.768
MOD_ProDKin_1	281	287	PF00069	0.700
MOD_ProDKin_1	41	47	PF00069	0.835
MOD_ProDKin_1	69	75	PF00069	0.705
MOD_ProDKin_1	82	88	PF00069	0.733
MOD_SUMO_for_1	1	4	PF00179	0.690
TRG_ER_diArg_1	105	108	PF00400	0.755
TRG_ER_diArg_1	129	132	PF00400	0.741
TRG_ER_diArg_1	209	211	PF00400	0.818
TRG_ER_diArg_1	270	272	PF00400	0.608
TRG_ER_diArg_1	8	11	PF00400	0.677
TRG_NLS_MonoExtC_3	268	274	PF00514	0.598
TRG_NLS_MonoExtC_3	34	39	PF00514	0.715
TRG_NLS_MonoExtN_4	33	39	PF00514	0.710
TRG_Pf-PMV_PEXEL_1	270	274	PF00026	0.611
TRG_Pf-PMV_PEXEL_1	299	304	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	8	13	PF00026	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HMT0	Leishmania braziliensis	61%	90%
A4IBC8	Leishmania infantum	97%	99%
E9AF84	Leishmania major	89%	100%
E9B6D9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%