Rad60-SLD_2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IF19_LEIDO

TriTrypDb:

LdBPK_312520.1 , LdCL_310033200 , LDHU3_31.4540

Length:

219

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 17
NetGPI	no	yes: 0, no: 17

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IF19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IF19

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	160	164	PF00656	0.493
CLV_NRD_NRD_1	181	183	PF00675	0.413
CLV_NRD_NRD_1	37	39	PF00675	0.453
CLV_PCSK_KEX2_1	181	183	PF00082	0.429
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.423
CLV_PCSK_SKI1_1	183	187	PF00082	0.502
CLV_PCSK_SKI1_1	206	210	PF00082	0.529
CLV_PCSK_SKI1_1	23	27	PF00082	0.428
DEG_COP1_1	100	110	PF00400	0.645
DOC_CYCLIN_RxL_1	178	188	PF00134	0.398
DOC_MAPK_gen_1	74	81	PF00069	0.408
DOC_MAPK_MEF2A_6	74	81	PF00069	0.408
DOC_MAPK_NFAT4_5	74	82	PF00069	0.410
DOC_PP1_RVXF_1	1	8	PF00149	0.385
DOC_USP7_MATH_1	89	93	PF00917	0.474
LIG_14-3-3_CanoR_1	158	165	PF00244	0.311
LIG_14-3-3_CanoR_1	60	70	PF00244	0.389
LIG_APCC_ABBAyCdc20_2	182	188	PF00400	0.389
LIG_BIR_II_1	1	5	PF00653	0.427
LIG_BRCT_BRCA1_1	66	70	PF00533	0.358
LIG_deltaCOP1_diTrp_1	153	159	PF00928	0.331
LIG_FHA_1	19	25	PF00498	0.417
LIG_FHA_1	31	37	PF00498	0.406
LIG_FHA_1	76	82	PF00498	0.323
LIG_FHA_2	158	164	PF00498	0.431
LIG_FHA_2	27	33	PF00498	0.381
LIG_FHA_2	95	101	PF00498	0.485
LIG_GBD_Chelix_1	167	175	PF00786	0.318
LIG_LIR_Gen_1	67	77	PF02991	0.500
LIG_LIR_Nem_3	67	73	PF02991	0.488
LIG_Pex14_1	155	159	PF04695	0.358
LIG_SH2_STAP1	165	169	PF00017	0.411
LIG_SH3_3	105	111	PF00018	0.689
LIG_SH3_3	83	89	PF00018	0.375
LIG_SUMO_SIM_anti_2	166	171	PF11976	0.430
LIG_SUMO_SIM_par_1	23	29	PF11976	0.417
LIG_SUMO_SIM_par_1	31	37	PF11976	0.433
LIG_TYR_ITIM	45	50	PF00017	0.490
LIG_UBA3_1	171	178	PF00899	0.477
MOD_CK1_1	109	115	PF00069	0.652
MOD_CK1_1	161	167	PF00069	0.410
MOD_CK1_1	64	70	PF00069	0.513
MOD_Cter_Amidation	179	182	PF01082	0.420
MOD_GlcNHglycan	145	148	PF01048	0.604
MOD_GlcNHglycan	65	69	PF01048	0.361
MOD_GSK3_1	106	113	PF00069	0.613
MOD_GSK3_1	157	164	PF00069	0.391
MOD_GSK3_1	26	33	PF00069	0.432
MOD_NEK2_1	116	121	PF00069	0.597
MOD_NEK2_1	151	156	PF00069	0.479
MOD_NEK2_2	75	80	PF00069	0.343
MOD_PIKK_1	130	136	PF00454	0.757
MOD_PIKK_1	18	24	PF00454	0.439
MOD_PK_1	106	112	PF00069	0.499
MOD_PK_1	158	164	PF00069	0.395
MOD_PKA_2	157	163	PF00069	0.331
MOD_PKA_2	61	67	PF00069	0.361
MOD_Plk_1	116	122	PF00069	0.624
MOD_Plk_4	151	157	PF00069	0.530
MOD_SUMO_rev_2	202	208	PF00179	0.416
TRG_ENDOCYTIC_2	47	50	PF00928	0.424
TRG_ER_diArg_1	182	185	PF00400	0.393
TRG_NLS_MonoCore_2	180	185	PF00514	0.400
TRG_NLS_MonoExtN_4	178	185	PF00514	0.403
TRG_Pf-PMV_PEXEL_1	23	28	PF00026	0.400

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I730	Leptomonas seymouri	29%	100%
A0A0N1I8Q6	Leptomonas seymouri	45%	96%
A0A0N1PCW5	Leptomonas seymouri	36%	100%
A0A3Q8IKA6	Leishmania donovani	23%	100%
A0A3S5H7Q5	Leishmania donovani	41%	93%
A4HJM7	Leishmania braziliensis	41%	100%
A4HJM8	Leishmania braziliensis	78%	100%
A4HJM9	Leishmania braziliensis	23%	100%
A4I749	Leishmania infantum	41%	100%
A4I750	Leishmania infantum	100%	100%
A4I751	Leishmania infantum	23%	100%
E9B243	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B244	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
E9B245	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
Q4Q616	Leishmania major	22%	100%
Q4Q617	Leishmania major	96%	100%