Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IF10_LEIDO

TriTrypDb:

LdBPK_210130.1 , LdCL_210006200 , LDHU3_21.0140

Length:

183

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	12
GO:0110165	cellular anatomical entity	1	12

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Expansion

Sequence features

A0A3Q8IF10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IF10

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	87	89	PF00675	0.286
CLV_PCSK_KEX2_1	87	89	PF00082	0.286
CLV_PCSK_SKI1_1	88	92	PF00082	0.296
DEG_APCC_DBOX_1	13	21	PF00400	0.490
DEG_Nend_UBRbox_2	1	3	PF02207	0.683
DEG_SPOP_SBC_1	174	178	PF00917	0.557
DOC_MAPK_gen_1	87	95	PF00069	0.459
DOC_MAPK_gen_1	9	19	PF00069	0.573
DOC_MAPK_HePTP_8	85	97	PF00069	0.515
DOC_MAPK_MEF2A_6	12	21	PF00069	0.452

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILT5	Leptomonas seymouri	27%	100%
A0A0N1PC80	Leptomonas seymouri	69%	100%
A0A0S4J4Y6	Bodo saltans	37%	100%
A0A0S4JQJ3	Bodo saltans	31%	100%
A0A1X0NXC4	Trypanosomatidae	42%	100%
A0A422N768	Trypanosoma rangeli	40%	100%
A4HBK6	Leishmania braziliensis	79%	100%
A4HZL0	Leishmania infantum	100%	100%
E9AUX5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9AZH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%

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