Cell_cycle_sequence_binding_phosphoprotein_(RBP33 )_putative/GeneDB:LmjF.35.0950

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cell cycle sequence binding phosphoprotein (RBP33), putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IEY4_LEIDO

TriTrypDb:

LdBPK_350970.1 , LdCL_350014500 , LDHU3_35.1180

Length:

413

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IEY4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEY4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.692
CLV_C14_Caspase3-7	159	163	PF00656	0.651
CLV_C14_Caspase3-7	180	184	PF00656	0.732
CLV_C14_Caspase3-7	379	383	PF00656	0.662
CLV_NRD_NRD_1	226	228	PF00675	0.383
CLV_NRD_NRD_1	259	261	PF00675	0.418
CLV_PCSK_KEX2_1	222	224	PF00082	0.421
CLV_PCSK_PC1ET2_1	222	224	PF00082	0.421
CLV_PCSK_SKI1_1	42	46	PF00082	0.596
DEG_COP1_1	119	129	PF00400	0.670
DOC_CYCLIN_RxL_1	313	325	PF00134	0.395
DOC_MAPK_gen_1	313	322	PF00069	0.328
DOC_MAPK_MEF2A_6	316	324	PF00069	0.324
DOC_PP1_RVXF_1	336	343	PF00149	0.315
DOC_USP7_MATH_1	146	150	PF00917	0.733
DOC_USP7_MATH_1	164	168	PF00917	0.531
DOC_USP7_MATH_1	210	214	PF00917	0.510
DOC_USP7_MATH_1	267	271	PF00917	0.459
DOC_USP7_MATH_1	31	35	PF00917	0.587
DOC_USP7_MATH_1	381	385	PF00917	0.592
DOC_USP7_MATH_1	74	78	PF00917	0.718
DOC_USP7_MATH_1	99	103	PF00917	0.585
DOC_WW_Pin1_4	103	108	PF00397	0.629
DOC_WW_Pin1_4	111	116	PF00397	0.640
DOC_WW_Pin1_4	125	130	PF00397	0.556
DOC_WW_Pin1_4	147	152	PF00397	0.660
DOC_WW_Pin1_4	19	24	PF00397	0.595
LIG_14-3-3_CanoR_1	290	297	PF00244	0.329
LIG_14-3-3_CanoR_1	42	47	PF00244	0.557
LIG_14-3-3_CanoR_1	94	98	PF00244	0.625
LIG_APCC_ABBA_1	12	17	PF00400	0.648
LIG_BIR_II_1	1	5	PF00653	0.655
LIG_BIR_III_4	382	386	PF00653	0.684
LIG_BRCT_BRCA1_1	340	344	PF00533	0.315
LIG_BRCT_BRCA1_1	348	352	PF00533	0.315
LIG_FHA_1	264	270	PF00498	0.457
LIG_Integrin_isoDGR_2	285	287	PF01839	0.529
LIG_LIR_Nem_3	349	355	PF02991	0.317
LIG_LIR_Nem_3	358	363	PF02991	0.323
LIG_MLH1_MIPbox_1	340	344	PF16413	0.315
LIG_SH2_NCK_1	194	198	PF00017	0.686
LIG_SH2_PTP2	240	243	PF00017	0.376
LIG_SH2_STAP1	194	198	PF00017	0.736
LIG_SH2_STAT5	229	232	PF00017	0.473
LIG_SH2_STAT5	240	243	PF00017	0.376
LIG_SH2_STAT5	3	6	PF00017	0.643
LIG_SH3_3	101	107	PF00018	0.622
LIG_SH3_3	123	129	PF00018	0.646
LIG_TRAF2_1	173	176	PF00917	0.516
LIG_TRAF2_1	292	295	PF00917	0.315
LIG_WRC_WIRS_1	360	365	PF05994	0.315
MOD_CK1_1	100	106	PF00069	0.615
MOD_CK1_1	128	134	PF00069	0.778
MOD_CK1_1	167	173	PF00069	0.605
MOD_CK1_1	34	40	PF00069	0.639
MOD_CK2_1	381	387	PF00069	0.681
MOD_DYRK1A_RPxSP_1	125	129	PF00069	0.612
MOD_DYRK1A_RPxSP_1	19	23	PF00069	0.673
MOD_GlcNHglycan	107	110	PF01048	0.744
MOD_GlcNHglycan	111	114	PF01048	0.625
MOD_GlcNHglycan	115	118	PF01048	0.593
MOD_GlcNHglycan	121	124	PF01048	0.643
MOD_GlcNHglycan	166	169	PF01048	0.635
MOD_GlcNHglycan	179	182	PF01048	0.530
MOD_GlcNHglycan	19	22	PF01048	0.608
MOD_GlcNHglycan	195	198	PF01048	0.652
MOD_GlcNHglycan	382	386	PF01048	0.607
MOD_GlcNHglycan	76	79	PF01048	0.665
MOD_GSK3_1	105	112	PF00069	0.656
MOD_GSK3_1	113	120	PF00069	0.580
MOD_GSK3_1	125	132	PF00069	0.646
MOD_GSK3_1	140	147	PF00069	0.776
MOD_GSK3_1	15	22	PF00069	0.610
MOD_GSK3_1	152	159	PF00069	0.683
MOD_GSK3_1	263	270	PF00069	0.475
MOD_GSK3_1	93	100	PF00069	0.550
MOD_LATS_1	156	162	PF00433	0.677
MOD_LATS_1	40	46	PF00433	0.712
MOD_N-GLC_1	100	105	PF02516	0.733
MOD_N-GLC_1	129	134	PF02516	0.658
MOD_N-GLC_1	152	157	PF02516	0.727
MOD_N-GLC_1	192	197	PF02516	0.684
MOD_N-GLC_1	263	268	PF02516	0.462
MOD_N-GLC_1	29	34	PF02516	0.715
MOD_NEK2_1	15	20	PF00069	0.617
MOD_NEK2_1	177	182	PF00069	0.600
MOD_NEK2_1	359	364	PF00069	0.315
MOD_NEK2_1	97	102	PF00069	0.608
MOD_NEK2_2	311	316	PF00069	0.315
MOD_PK_1	52	58	PF00069	0.555
MOD_PKA_1	338	344	PF00069	0.315
MOD_PKA_2	246	252	PF00069	0.401
MOD_PKA_2	74	80	PF00069	0.663
MOD_PKA_2	93	99	PF00069	0.417
MOD_Plk_1	100	106	PF00069	0.636
MOD_Plk_1	139	145	PF00069	0.656
MOD_Plk_1	263	269	PF00069	0.461
MOD_Plk_1	29	35	PF00069	0.635
MOD_Plk_1	346	352	PF00069	0.315
MOD_Plk_4	42	48	PF00069	0.657
MOD_Plk_4	52	58	PF00069	0.454
MOD_Plk_4	59	65	PF00069	0.383
MOD_ProDKin_1	103	109	PF00069	0.630
MOD_ProDKin_1	111	117	PF00069	0.638
MOD_ProDKin_1	125	131	PF00069	0.555
MOD_ProDKin_1	147	153	PF00069	0.661
MOD_ProDKin_1	19	25	PF00069	0.597
MOD_SUMO_for_1	281	284	PF00179	0.437
MOD_SUMO_rev_2	272	281	PF00179	0.458
MOD_SUMO_rev_2	330	340	PF00179	0.315
TRG_DiLeu_BaEn_2	213	219	PF01217	0.404
TRG_DiLeu_BaEn_4	204	210	PF01217	0.576
TRG_DiLeu_BaLyEn_6	49	54	PF01217	0.557
TRG_ENDOCYTIC_2	240	243	PF00928	0.376
TRG_ENDOCYTIC_2	360	363	PF00928	0.351
TRG_ER_diArg_1	223	226	PF00400	0.408
TRG_Pf-PMV_PEXEL_1	287	291	PF00026	0.395
TRG_Pf-PMV_PEXEL_1	353	358	PF00026	0.315

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I362	Leptomonas seymouri	68%	100%
A4HMC6	Leishmania braziliensis	87%	99%
A4IAZ2	Leishmania infantum	100%	100%
E9AES0	Leishmania major	98%	100%
E9B5X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%