Putative HEAT repeat protein family protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

proteasome regulatory non-ATP-ase subunit 2, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IEW8_LEIDO

TriTrypDb:

LdBPK_281850.1 , LdCL_280023500 , LDHU3_28.2450

Length:

991

Annotations

Annotations by Jardim et al.

Proteasome, proteasome regulatory non-ATP-ase subunit 2

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 2
Pissara et al.	yes	yes: 6

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 4

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0008540	proteasome regulatory particle, base subcomplex	2	12
GO:0032991	protein-containing complex	1	12
GO:0005634	nucleus	5	1
GO:0034515	proteasome storage granule	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3Q8IEW8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEW8

Function

Biological processes
Term	Name	Level	Count
GO:0009894	regulation of catabolic process	4	12
GO:0019222	regulation of metabolic process	3	12
GO:0042176	regulation of protein catabolic process	5	12
GO:0050789	regulation of biological process	2	12
GO:0051171	regulation of nitrogen compound metabolic process	4	12
GO:0051246	regulation of protein metabolic process	5	12
GO:0060255	regulation of macromolecule metabolic process	4	12
GO:0065007	biological regulation	1	12
GO:0080090	regulation of primary metabolic process	4	12
GO:0006508	proteolysis	4	1
GO:0006511	ubiquitin-dependent protein catabolic process	7	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010498	proteasomal protein catabolic process	5	1
GO:0019538	protein metabolic process	3	1
GO:0019941	modification-dependent protein catabolic process	6	1
GO:0030163	protein catabolic process	4	1
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043632	modification-dependent macromolecule catabolic process	5	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0051603	proteolysis involved in protein catabolic process	5	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901565	organonitrogen compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0030234	enzyme regulator activity	2	12
GO:0098772	molecular function regulator activity	1	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	295	299	PF00656	0.595
CLV_C14_Caspase3-7	318	322	PF00656	0.524
CLV_C14_Caspase3-7	396	400	PF00656	0.337
CLV_C14_Caspase3-7	524	528	PF00656	0.477
CLV_NRD_NRD_1	202	204	PF00675	0.337
CLV_NRD_NRD_1	476	478	PF00675	0.431
CLV_NRD_NRD_1	62	64	PF00675	0.478
CLV_NRD_NRD_1	638	640	PF00675	0.253
CLV_NRD_NRD_1	858	860	PF00675	0.399
CLV_NRD_NRD_1	867	869	PF00675	0.399
CLV_PCSK_FUR_1	474	478	PF00082	0.408
CLV_PCSK_FUR_1	865	869	PF00082	0.272
CLV_PCSK_KEX2_1	202	204	PF00082	0.337
CLV_PCSK_KEX2_1	28	30	PF00082	0.337
CLV_PCSK_KEX2_1	476	478	PF00082	0.391
CLV_PCSK_KEX2_1	62	64	PF00082	0.478
CLV_PCSK_KEX2_1	638	640	PF00082	0.253
CLV_PCSK_KEX2_1	843	845	PF00082	0.471
CLV_PCSK_KEX2_1	867	869	PF00082	0.263
CLV_PCSK_KEX2_1	899	901	PF00082	0.444
CLV_PCSK_PC1ET2_1	28	30	PF00082	0.337
CLV_PCSK_PC1ET2_1	843	845	PF00082	0.471
CLV_PCSK_PC1ET2_1	899	901	PF00082	0.444
CLV_PCSK_SKI1_1	173	177	PF00082	0.401
CLV_PCSK_SKI1_1	203	207	PF00082	0.326
CLV_PCSK_SKI1_1	371	375	PF00082	0.551
CLV_PCSK_SKI1_1	733	737	PF00082	0.359
CLV_PCSK_SKI1_1	837	841	PF00082	0.274
CLV_PCSK_SKI1_1	84	88	PF00082	0.464
CLV_PCSK_SKI1_1	843	847	PF00082	0.269
CLV_PCSK_SKI1_1	9	13	PF00082	0.345
CLV_PCSK_SKI1_1	98	102	PF00082	0.355
DEG_APCC_DBOX_1	202	210	PF00400	0.315
DEG_APCC_KENBOX_2	723	727	PF00400	0.488
DEG_COP1_1	977	987	PF00400	0.611
DEG_SPOP_SBC_1	293	297	PF00917	0.682
DEG_SPOP_SBC_1	854	858	PF00917	0.347
DOC_AGCK_PIF_2	259	264	PF00069	0.324
DOC_ANK_TNKS_1	867	874	PF00023	0.318
DOC_CKS1_1	117	122	PF01111	0.553
DOC_CYCLIN_RxL_1	201	211	PF00134	0.336
DOC_CYCLIN_RxL_1	95	104	PF00134	0.379
DOC_CYCLIN_yClb5_NLxxxL_5	650	659	PF00134	0.399
DOC_CYCLIN_yCln2_LP_2	923	929	PF00134	0.312
DOC_CYCLIN_yCln2_LP_2	970	976	PF00134	0.597
DOC_MAPK_FxFP_2	988	991	PF00069	0.639
DOC_MAPK_gen_1	202	208	PF00069	0.320
DOC_MAPK_gen_1	728	736	PF00069	0.391
DOC_MAPK_gen_1	777	785	PF00069	0.278
DOC_MAPK_gen_1	949	957	PF00069	0.408
DOC_MAPK_HePTP_8	356	368	PF00069	0.265
DOC_MAPK_MEF2A_6	130	138	PF00069	0.485
DOC_MAPK_MEF2A_6	359	368	PF00069	0.267
DOC_MAPK_MEF2A_6	651	659	PF00069	0.263
DOC_MAPK_MEF2A_6	672	681	PF00069	0.253
DOC_MAPK_MEF2A_6	707	716	PF00069	0.253
DOC_MAPK_MEF2A_6	780	787	PF00069	0.284
DOC_MAPK_MEF2A_6	949	957	PF00069	0.399
DOC_MAPK_RevD_3	189	203	PF00069	0.357
DOC_PP1_RVXF_1	162	168	PF00149	0.322
DOC_PP1_RVXF_1	249	256	PF00149	0.450
DOC_PP2B_LxvP_1	817	820	PF13499	0.268
DOC_PP2B_LxvP_1	970	973	PF13499	0.514
DOC_PP4_FxxP_1	650	653	PF00568	0.347
DOC_PP4_FxxP_1	988	991	PF00568	0.546
DOC_USP7_MATH_1	292	296	PF00917	0.641
DOC_USP7_MATH_1	304	308	PF00917	0.709
DOC_USP7_MATH_1	309	313	PF00917	0.478
DOC_USP7_MATH_1	376	380	PF00917	0.473
DOC_USP7_MATH_1	420	424	PF00917	0.445
DOC_USP7_MATH_1	879	883	PF00917	0.345
DOC_USP7_UBL2_3	620	624	PF12436	0.318
DOC_WW_Pin1_4	116	121	PF00397	0.535
DOC_WW_Pin1_4	311	316	PF00397	0.533
DOC_WW_Pin1_4	331	336	PF00397	0.601
DOC_WW_Pin1_4	465	470	PF00397	0.457
DOC_WW_Pin1_4	665	670	PF00397	0.318
DOC_WW_Pin1_4	871	876	PF00397	0.388
LIG_14-3-3_CanoR_1	29	34	PF00244	0.374
LIG_14-3-3_CanoR_1	377	381	PF00244	0.587
LIG_14-3-3_CanoR_1	429	438	PF00244	0.496
LIG_14-3-3_CanoR_1	62	68	PF00244	0.452
LIG_14-3-3_CanoR_1	638	645	PF00244	0.339
LIG_14-3-3_CanoR_1	765	770	PF00244	0.308
LIG_14-3-3_CanoR_1	844	854	PF00244	0.318
LIG_14-3-3_CanoR_1	928	936	PF00244	0.253
LIG_14-3-3_CanoR_1	98	106	PF00244	0.323
LIG_AP2alpha_2	598	600	PF02296	0.304
LIG_BIR_III_4	298	302	PF00653	0.592
LIG_BIR_III_4	321	325	PF00653	0.588
LIG_BIR_III_4	761	765	PF00653	0.280
LIG_deltaCOP1_diTrp_1	598	607	PF00928	0.277
LIG_DLG_GKlike_1	63	71	PF00625	0.440
LIG_eIF4E_1	190	196	PF01652	0.387
LIG_eIF4E_1	793	799	PF01652	0.312
LIG_FHA_1	186	192	PF00498	0.305
LIG_FHA_1	212	218	PF00498	0.433
LIG_FHA_1	236	242	PF00498	0.318
LIG_FHA_1	346	352	PF00498	0.380
LIG_FHA_1	422	428	PF00498	0.315
LIG_FHA_1	59	65	PF00498	0.338
LIG_FHA_1	766	772	PF00498	0.346
LIG_FHA_1	806	812	PF00498	0.260
LIG_FHA_1	830	836	PF00498	0.399
LIG_FHA_1	845	851	PF00498	0.399
LIG_FHA_1	95	101	PF00498	0.423
LIG_FHA_2	146	152	PF00498	0.485
LIG_FHA_2	316	322	PF00498	0.619
LIG_FHA_2	394	400	PF00498	0.329
LIG_FHA_2	522	528	PF00498	0.463
LIG_FHA_2	627	633	PF00498	0.275
LIG_FHA_2	647	653	PF00498	0.132
LIG_FHA_2	720	726	PF00498	0.336
LIG_FHA_2	856	862	PF00498	0.253
LIG_FHA_2	89	95	PF00498	0.501
LIG_FHA_2	959	965	PF00498	0.419
LIG_GBD_Chelix_1	253	261	PF00786	0.373
LIG_GBD_Chelix_1	273	281	PF00786	0.210
LIG_LIR_Apic_2	649	653	PF02991	0.347
LIG_LIR_Apic_2	831	836	PF02991	0.265
LIG_LIR_Apic_2	986	991	PF02991	0.547
LIG_LIR_Gen_1	132	143	PF02991	0.355
LIG_LIR_Gen_1	35	46	PF02991	0.427
LIG_LIR_Gen_1	363	373	PF02991	0.366
LIG_LIR_Gen_1	513	523	PF02991	0.312
LIG_LIR_Gen_1	598	608	PF02991	0.279
LIG_LIR_Gen_1	693	703	PF02991	0.318
LIG_LIR_Gen_1	917	927	PF02991	0.264
LIG_LIR_LC3C_4	18	23	PF02991	0.405
LIG_LIR_Nem_3	111	116	PF02991	0.352
LIG_LIR_Nem_3	132	138	PF02991	0.354
LIG_LIR_Nem_3	219	225	PF02991	0.415
LIG_LIR_Nem_3	35	41	PF02991	0.330
LIG_LIR_Nem_3	513	519	PF02991	0.315
LIG_LIR_Nem_3	598	603	PF02991	0.291
LIG_LIR_Nem_3	693	699	PF02991	0.318
LIG_LIR_Nem_3	70	76	PF02991	0.400
LIG_LIR_Nem_3	731	735	PF02991	0.369
LIG_LIR_Nem_3	749	754	PF02991	0.194
LIG_LIR_Nem_3	917	923	PF02991	0.262
LIG_LIR_Nem_3	942	948	PF02991	0.261
LIG_LYPXL_yS_3	795	798	PF13949	0.423
LIG_MAD2	661	669	PF02301	0.268
LIG_PCNA_PIPBox_1	436	445	PF02747	0.451
LIG_Pex14_2	163	167	PF04695	0.332
LIG_Pex14_2	255	259	PF04695	0.341
LIG_Pex14_2	788	792	PF04695	0.275
LIG_PTAP_UEV_1	305	310	PF05743	0.507
LIG_PTB_Apo_2	183	190	PF02174	0.319
LIG_PTB_Apo_2	263	270	PF02174	0.311
LIG_PTB_Apo_2	553	560	PF02174	0.467
LIG_PTB_Phospho_1	263	269	PF10480	0.459
LIG_PTB_Phospho_1	553	559	PF10480	0.463
LIG_SH2_CRK	467	471	PF00017	0.401
LIG_SH2_CRK	516	520	PF00017	0.395
LIG_SH2_CRK	833	837	PF00017	0.373
LIG_SH2_GRB2like	79	82	PF00017	0.473
LIG_SH2_PTP2	945	948	PF00017	0.399
LIG_SH2_SRC	355	358	PF00017	0.329
LIG_SH2_SRC	454	457	PF00017	0.331
LIG_SH2_STAP1	357	361	PF00017	0.476
LIG_SH2_STAP1	516	520	PF00017	0.395
LIG_SH2_STAP1	79	83	PF00017	0.374
LIG_SH2_STAT3	264	267	PF00017	0.324
LIG_SH2_STAT3	705	708	PF00017	0.399
LIG_SH2_STAT5	113	116	PF00017	0.410
LIG_SH2_STAT5	190	193	PF00017	0.417
LIG_SH2_STAT5	213	216	PF00017	0.428
LIG_SH2_STAT5	269	272	PF00017	0.450
LIG_SH2_STAT5	355	358	PF00017	0.373
LIG_SH2_STAT5	365	368	PF00017	0.405
LIG_SH2_STAT5	442	445	PF00017	0.361
LIG_SH2_STAT5	481	484	PF00017	0.355
LIG_SH2_STAT5	705	708	PF00017	0.292
LIG_SH2_STAT5	73	76	PF00017	0.391
LIG_SH2_STAT5	753	756	PF00017	0.405
LIG_SH2_STAT5	797	800	PF00017	0.262
LIG_SH2_STAT5	822	825	PF00017	0.287
LIG_SH2_STAT5	945	948	PF00017	0.399
LIG_SH3_1	944	950	PF00018	0.268
LIG_SH3_3	303	309	PF00018	0.572
LIG_SH3_3	329	335	PF00018	0.554
LIG_SH3_3	441	447	PF00018	0.453
LIG_SH3_3	869	875	PF00018	0.263
LIG_SH3_3	944	950	PF00018	0.268
LIG_SH3_3	981	987	PF00018	0.530
LIG_SUMO_SIM_anti_2	16	25	PF11976	0.497
LIG_SUMO_SIM_par_1	10	19	PF11976	0.564
LIG_SUMO_SIM_par_1	338	344	PF11976	0.394
LIG_SUMO_SIM_par_1	539	545	PF11976	0.379
LIG_SUMO_SIM_par_1	623	629	PF11976	0.324
LIG_SUMO_SIM_par_1	797	802	PF11976	0.263
LIG_SUMO_SIM_par_1	972	978	PF11976	0.618
LIG_TRAF2_1	115	118	PF00917	0.494
LIG_TRAF2_1	16	19	PF00917	0.382
LIG_TRAF2_1	453	456	PF00917	0.327
LIG_TRAF2_1	558	561	PF00917	0.413
LIG_TRAF2_1	914	917	PF00917	0.296
LIG_TYR_ITIM	220	225	PF00017	0.405
LIG_TYR_ITIM	465	470	PF00017	0.377
LIG_TYR_ITIM	943	948	PF00017	0.274
LIG_UBA3_1	134	140	PF00899	0.331
LIG_UBA3_1	195	204	PF00899	0.365
LIG_UBA3_1	24	28	PF00899	0.461
LIG_UBA3_1	367	372	PF00899	0.303
LIG_UBA3_1	47	56	PF00899	0.423
LIG_WRC_WIRS_1	34	39	PF05994	0.427
LIG_WRC_WIRS_1	647	652	PF05994	0.347
MOD_CDK_SPxxK_3	331	338	PF00069	0.527
MOD_CDK_SPxxK_3	665	672	PF00069	0.318
MOD_CK1_1	314	320	PF00069	0.628
MOD_CK1_1	341	347	PF00069	0.432
MOD_CK1_1	394	400	PF00069	0.373
MOD_CK1_1	448	454	PF00069	0.448
MOD_CK1_1	935	941	PF00069	0.343
MOD_CK1_1	99	105	PF00069	0.318
MOD_CK2_1	13	19	PF00069	0.417
MOD_CK2_1	719	725	PF00069	0.334
MOD_CK2_1	855	861	PF00069	0.253
MOD_CK2_1	958	964	PF00069	0.402
MOD_GlcNHglycan	180	183	PF01048	0.340
MOD_GlcNHglycan	270	273	PF01048	0.363
MOD_GlcNHglycan	306	309	PF01048	0.649
MOD_GlcNHglycan	321	325	PF01048	0.618
MOD_GlcNHglycan	343	346	PF01048	0.358
MOD_GlcNHglycan	393	396	PF01048	0.352
MOD_GlcNHglycan	40	44	PF01048	0.471
MOD_GlcNHglycan	544	547	PF01048	0.302
MOD_GlcNHglycan	595	598	PF01048	0.473
MOD_GlcNHglycan	6	9	PF01048	0.416
MOD_GlcNHglycan	681	684	PF01048	0.298
MOD_GlcNHglycan	756	759	PF01048	0.479
MOD_GlcNHglycan	881	884	PF01048	0.361
MOD_GlcNHglycan	909	912	PF01048	0.336
MOD_GSK3_1	134	141	PF00069	0.400
MOD_GSK3_1	174	181	PF00069	0.485
MOD_GSK3_1	211	218	PF00069	0.424
MOD_GSK3_1	29	36	PF00069	0.542
MOD_GSK3_1	304	311	PF00069	0.674
MOD_GSK3_1	341	348	PF00069	0.376
MOD_GSK3_1	416	423	PF00069	0.388
MOD_GSK3_1	63	70	PF00069	0.382
MOD_GSK3_1	679	686	PF00069	0.296
MOD_LATS_1	369	375	PF00433	0.488
MOD_N-GLC_1	145	150	PF02516	0.522
MOD_N-GLC_1	185	190	PF02516	0.323
MOD_N-GLC_1	382	387	PF02516	0.313
MOD_N-GLC_1	765	770	PF02516	0.299
MOD_N-GLC_1	813	818	PF02516	0.399
MOD_N-GLC_2	654	656	PF02516	0.399
MOD_NEK2_1	101	106	PF00069	0.242
MOD_NEK2_1	134	139	PF00069	0.418
MOD_NEK2_1	176	181	PF00069	0.394
MOD_NEK2_1	185	190	PF00069	0.318
MOD_NEK2_1	33	38	PF00069	0.339
MOD_NEK2_1	391	396	PF00069	0.385
MOD_NEK2_1	542	547	PF00069	0.296
MOD_NEK2_1	626	631	PF00069	0.305
MOD_NEK2_1	663	668	PF00069	0.262
MOD_NEK2_1	67	72	PF00069	0.362
MOD_NEK2_1	679	684	PF00069	0.253
MOD_NEK2_1	799	804	PF00069	0.276
MOD_NEK2_1	855	860	PF00069	0.253
MOD_NEK2_1	93	98	PF00069	0.436
MOD_NEK2_1	958	963	PF00069	0.287
MOD_NEK2_2	646	651	PF00069	0.253
MOD_NEK2_2	79	84	PF00069	0.357
MOD_NEK2_2	820	825	PF00069	0.287
MOD_PIKK_1	67	73	PF00454	0.398
MOD_PK_1	338	344	PF00069	0.446
MOD_PK_1	445	451	PF00069	0.560
MOD_PK_1	624	630	PF00069	0.264
MOD_PKA_1	28	34	PF00069	0.380
MOD_PKA_1	371	377	PF00069	0.516
MOD_PKA_2	28	34	PF00069	0.458
MOD_PKA_2	376	382	PF00069	0.507
MOD_PKA_2	475	481	PF00069	0.424
MOD_PKA_2	637	643	PF00069	0.399
MOD_PKA_2	746	752	PF00069	0.418
MOD_PKA_2	927	933	PF00069	0.253
MOD_Plk_1	145	151	PF00069	0.442
MOD_Plk_1	185	191	PF00069	0.319
MOD_Plk_1	197	203	PF00069	0.342
MOD_Plk_1	382	388	PF00069	0.312
MOD_Plk_1	765	771	PF00069	0.300
MOD_Plk_1	813	819	PF00069	0.314
MOD_Plk_1	820	826	PF00069	0.259
MOD_Plk_2-3	145	151	PF00069	0.498
MOD_Plk_4	101	107	PF00069	0.306
MOD_Plk_4	109	115	PF00069	0.326
MOD_Plk_4	138	144	PF00069	0.411
MOD_Plk_4	29	35	PF00069	0.338
MOD_Plk_4	338	344	PF00069	0.400
MOD_Plk_4	376	382	PF00069	0.407
MOD_Plk_4	63	69	PF00069	0.442
MOD_Plk_4	640	646	PF00069	0.268
MOD_Plk_4	835	841	PF00069	0.264
MOD_ProDKin_1	116	122	PF00069	0.544
MOD_ProDKin_1	311	317	PF00069	0.534
MOD_ProDKin_1	331	337	PF00069	0.592
MOD_ProDKin_1	465	471	PF00069	0.465
MOD_ProDKin_1	665	671	PF00069	0.318
MOD_ProDKin_1	871	877	PF00069	0.388
MOD_SUMO_for_1	129	132	PF00179	0.507
MOD_SUMO_rev_2	145	155	PF00179	0.511
MOD_SUMO_rev_2	333	340	PF00179	0.472
MOD_SUMO_rev_2	731	740	PF00179	0.473
TRG_DiLeu_BaEn_1	17	22	PF01217	0.420
TRG_DiLeu_BaEn_1	583	588	PF01217	0.317
TRG_DiLeu_BaLyEn_6	204	209	PF01217	0.345
TRG_DiLeu_BaLyEn_6	43	48	PF01217	0.361
TRG_DiLeu_BaLyEn_6	730	735	PF01217	0.401
TRG_ENDOCYTIC_2	222	225	PF00928	0.395
TRG_ENDOCYTIC_2	365	368	PF00928	0.386
TRG_ENDOCYTIC_2	467	470	PF00928	0.394
TRG_ENDOCYTIC_2	516	519	PF00928	0.396
TRG_ENDOCYTIC_2	73	76	PF00928	0.391
TRG_ENDOCYTIC_2	795	798	PF00928	0.284
TRG_ENDOCYTIC_2	945	948	PF00928	0.287
TRG_ER_diArg_1	201	203	PF00400	0.320
TRG_ER_diArg_1	62	64	PF00400	0.478
TRG_ER_diArg_1	637	639	PF00400	0.253
TRG_ER_diArg_1	775	778	PF00400	0.313
TRG_ER_diArg_1	864	867	PF00400	0.399
TRG_Pf-PMV_PEXEL_1	207	211	PF00026	0.324
TRG_Pf-PMV_PEXEL_1	437	441	PF00026	0.507
TRG_Pf-PMV_PEXEL_1	661	665	PF00026	0.268
TRG_Pf-PMV_PEXEL_1	733	737	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	98	103	PF00026	0.353

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8Y0	Leptomonas seymouri	82%	100%
A0A0S4JC57	Bodo saltans	50%	96%
A0A1X0NQV9	Trypanosomatidae	55%	98%
A0A3R7KVS9	Trypanosoma rangeli	58%	100%
A4HGM6	Leishmania braziliensis	93%	100%
A4I3Q0	Leishmania infantum	100%	100%
D0A8B2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
E9AZZ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
O48844	Arabidopsis thaliana	37%	99%
O74762	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
O88761	Rattus norvegicus	39%	100%
P32565	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
Q18115	Caenorhabditis elegans	29%	100%
Q3TXS7	Mus musculus	38%	100%
Q4Q893	Leishmania major	96%	98%
Q54JM5	Dictyostelium discoideum	34%	100%
Q5F418	Gallus gallus	38%	100%
Q5R5S4	Pongo abelii	38%	100%
Q6FIP2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	100%
Q75CF3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	30%	100%
Q99460	Homo sapiens	38%	100%
Q9MAT0	Arabidopsis thaliana	37%	99%
Q9V3P6	Drosophila melanogaster	35%	97%
V5AV92	Trypanosoma cruzi	58%	100%