Translation_factor_sui1_putative/GeneDB:LmjF.24.1 210

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Eukaryotic translation initiation factor 1, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IEW2_LEIDO

TriTrypDb:

LdBPK_241240.1 , LdCL_240017500 , LDHU3_24.1460

Length:

107

Annotations

Annotations by Jardim et al.

Translation, translation factor sui1

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3Q8IEW2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEW2

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0003723	RNA binding	4	1
GO:0003743	translation initiation factor activity	4	11
GO:0005488	binding	1	11
GO:0008135	translation factor activity, RNA binding	3	11
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	69	73	PF00656	0.574
CLV_NRD_NRD_1	31	33	PF00675	0.320
CLV_NRD_NRD_1	51	53	PF00675	0.334
CLV_NRD_NRD_1	59	61	PF00675	0.341
CLV_PCSK_KEX2_1	51	53	PF00082	0.334
CLV_PCSK_KEX2_1	59	61	PF00082	0.357
CLV_PCSK_PC7_1	55	61	PF00082	0.338
CLV_PCSK_SKI1_1	17	21	PF00082	0.623
CLV_PCSK_SKI1_1	36	40	PF00082	0.232
CLV_PCSK_SKI1_1	88	92	PF00082	0.331

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5I4	Leptomonas seymouri	93%	100%
A0A0S4J1Q1	Bodo saltans	70%	100%
A0A1X0NVM9	Trypanosomatidae	74%	98%
A0A422NQ99	Trypanosoma rangeli	80%	98%
A4HDH8	Leishmania braziliensis	96%	100%
A4I0V9	Leishmania infantum	100%	100%
A6MZM2	Oryza sativa subsp. indica	40%	93%
D0A790	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	98%
E9AWW3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
O48650	Salix bakko	42%	95%

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