LeishMANIAdb
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Hypothetical_protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8IEU5_LEIDO
TriTrypDb:
LdCL_330019900 , LDHU3_33.2030
Length:
128

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IEU5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEU5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 50 54 PF00656 0.699
DEG_SPOP_SBC_1 23 27 PF00917 0.708
DEG_SPOP_SBC_1 43 47 PF00917 0.578
DOC_USP7_MATH_1 43 47 PF00917 0.653
DOC_USP7_MATH_1 52 56 PF00917 0.676
DOC_USP7_MATH_1 90 94 PF00917 0.661
DOC_WW_Pin1_4 26 31 PF00397 0.675
DOC_WW_Pin1_4 48 53 PF00397 0.664
DOC_WW_Pin1_4 59 64 PF00397 0.544
DOC_WW_Pin1_4 80 85 PF00397 0.492
LIG_FHA_1 14 20 PF00498 0.611
LIG_FHA_1 27 33 PF00498 0.622
LIG_MYND_1 30 34 PF01753 0.582
LIG_SH2_STAT5 79 82 PF00017 0.484
LIG_SH3_3 27 33 PF00018 0.700
LIG_SH3_3 78 84 PF00018 0.456
LIG_SUMO_SIM_par_1 114 121 PF11976 0.508
MOD_CDK_SPxxK_3 80 87 PF00069 0.497
MOD_CK1_1 25 31 PF00069 0.633
MOD_CK1_1 45 51 PF00069 0.643
MOD_CK1_1 93 99 PF00069 0.508
MOD_GlcNHglycan 3 6 PF01048 0.551
MOD_GlcNHglycan 74 77 PF01048 0.495
MOD_GlcNHglycan 8 11 PF01048 0.534
MOD_GSK3_1 19 26 PF00069 0.741
MOD_GSK3_1 43 50 PF00069 0.638
MOD_NEK2_1 13 18 PF00069 0.643
MOD_NEK2_1 19 24 PF00069 0.627
MOD_PIKK_1 13 19 PF00454 0.566
MOD_Plk_4 52 58 PF00069 0.723
MOD_ProDKin_1 26 32 PF00069 0.673
MOD_ProDKin_1 48 54 PF00069 0.663
MOD_ProDKin_1 59 65 PF00069 0.541
MOD_ProDKin_1 80 86 PF00069 0.491

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4F5 Leptomonas seymouri 54% 100%
D0A4Z4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 80%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS