LeishMANIAdb
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Mitochondrial SSU ribosomal protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mitochondrial SSU ribosomal protein, putative
Gene product:
Mitochondrial SSU ribosomal protein, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IEU0_LEIDO
TriTrypDb:
LdBPK_240850.1 , LdCL_240013500 , LDHU3_24.0990
Length:
811

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 2
GO:0043226 organelle 2 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 3
GO:0005737 cytoplasm 2 1

Expansion

Sequence features

A0A3Q8IEU0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEU0

PDB structure(s): 7ane_ad

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 183 187 PF00656 0.513
CLV_C14_Caspase3-7 410 414 PF00656 0.560
CLV_NRD_NRD_1 339 341 PF00675 0.568
CLV_NRD_NRD_1 466 468 PF00675 0.477
CLV_NRD_NRD_1 605 607 PF00675 0.439
CLV_NRD_NRD_1 756 758 PF00675 0.505
CLV_NRD_NRD_1 785 787 PF00675 0.604
CLV_NRD_NRD_1 788 790 PF00675 0.549
CLV_PCSK_FUR_1 633 637 PF00082 0.412
CLV_PCSK_KEX2_1 339 341 PF00082 0.568
CLV_PCSK_KEX2_1 38 40 PF00082 0.523
CLV_PCSK_KEX2_1 466 468 PF00082 0.482
CLV_PCSK_KEX2_1 604 606 PF00082 0.405
CLV_PCSK_KEX2_1 617 619 PF00082 0.397
CLV_PCSK_KEX2_1 635 637 PF00082 0.315
CLV_PCSK_KEX2_1 666 668 PF00082 0.466
CLV_PCSK_KEX2_1 785 787 PF00082 0.653
CLV_PCSK_KEX2_1 94 96 PF00082 0.539
CLV_PCSK_PC1ET2_1 38 40 PF00082 0.622
CLV_PCSK_PC1ET2_1 617 619 PF00082 0.404
CLV_PCSK_PC1ET2_1 635 637 PF00082 0.416
CLV_PCSK_PC1ET2_1 666 668 PF00082 0.490
CLV_PCSK_PC1ET2_1 94 96 PF00082 0.539
CLV_PCSK_SKI1_1 136 140 PF00082 0.444
CLV_PCSK_SKI1_1 250 254 PF00082 0.576
CLV_PCSK_SKI1_1 297 301 PF00082 0.460
CLV_PCSK_SKI1_1 475 479 PF00082 0.522
CLV_PCSK_SKI1_1 487 491 PF00082 0.444
CLV_PCSK_SKI1_1 587 591 PF00082 0.427
CLV_PCSK_SKI1_1 617 621 PF00082 0.418
CLV_PCSK_SKI1_1 740 744 PF00082 0.540
CLV_PCSK_SKI1_1 84 88 PF00082 0.669
DEG_APCC_DBOX_1 260 268 PF00400 0.449
DEG_COP1_1 324 332 PF00400 0.520
DEG_SCF_FBW7_2 326 331 PF00400 0.504
DOC_CKS1_1 323 328 PF01111 0.501
DOC_CYCLIN_yCln2_LP_2 742 748 PF00134 0.526
DOC_MAPK_gen_1 135 141 PF00069 0.440
DOC_MAPK_gen_1 287 296 PF00069 0.418
DOC_MAPK_gen_1 604 611 PF00069 0.510
DOC_MAPK_MEF2A_6 290 298 PF00069 0.409
DOC_MAPK_MEF2A_6 394 401 PF00069 0.412
DOC_PP1_RVXF_1 616 623 PF00149 0.392
DOC_PP2B_LxvP_1 265 268 PF13499 0.457
DOC_PP2B_LxvP_1 280 283 PF13499 0.453
DOC_PP2B_LxvP_1 500 503 PF13499 0.447
DOC_PP4_FxxP_1 383 386 PF00568 0.473
DOC_PP4_FxxP_1 751 754 PF00568 0.501
DOC_PP4_FxxP_1 788 791 PF00568 0.594
DOC_PP4_MxPP_1 746 749 PF00568 0.513
DOC_USP7_MATH_1 513 517 PF00917 0.483
DOC_USP7_UBL2_3 743 747 PF12436 0.594
DOC_WW_Pin1_4 252 257 PF00397 0.579
DOC_WW_Pin1_4 322 327 PF00397 0.471
DOC_WW_Pin1_4 341 346 PF00397 0.470
DOC_WW_Pin1_4 352 357 PF00397 0.443
DOC_WW_Pin1_4 453 458 PF00397 0.444
DOC_WW_Pin1_4 712 717 PF00397 0.570
LIG_14-3-3_CanoR_1 202 207 PF00244 0.420
LIG_14-3-3_CanoR_1 234 242 PF00244 0.413
LIG_14-3-3_CanoR_1 254 260 PF00244 0.273
LIG_14-3-3_CanoR_1 3 7 PF00244 0.722
LIG_14-3-3_CanoR_1 525 530 PF00244 0.528
LIG_14-3-3_CanoR_1 733 742 PF00244 0.523
LIG_APCC_ABBA_1 405 410 PF00400 0.571
LIG_BIR_III_2 152 156 PF00653 0.596
LIG_BRCT_BRCA1_1 379 383 PF00533 0.459
LIG_BRCT_MDC1_1 807 811 PF00533 0.640
LIG_deltaCOP1_diTrp_1 224 232 PF00928 0.398
LIG_DLG_GKlike_1 21 28 PF00625 0.585
LIG_FHA_1 106 112 PF00498 0.501
LIG_FHA_1 207 213 PF00498 0.369
LIG_FHA_1 224 230 PF00498 0.405
LIG_FHA_1 289 295 PF00498 0.389
LIG_FHA_1 453 459 PF00498 0.393
LIG_FHA_1 577 583 PF00498 0.474
LIG_FHA_1 683 689 PF00498 0.532
LIG_FHA_1 81 87 PF00498 0.521
LIG_FHA_2 181 187 PF00498 0.513
LIG_FHA_2 203 209 PF00498 0.473
LIG_FHA_2 258 264 PF00498 0.469
LIG_FHA_2 425 431 PF00498 0.544
LIG_FHA_2 543 549 PF00498 0.476
LIG_FHA_2 649 655 PF00498 0.413
LIG_FHA_2 68 74 PF00498 0.671
LIG_FHA_2 790 796 PF00498 0.583
LIG_GBD_Chelix_1 397 405 PF00786 0.531
LIG_Integrin_isoDGR_2 362 364 PF01839 0.513
LIG_LIR_Apic_2 380 386 PF02991 0.482
LIG_LIR_Apic_2 771 777 PF02991 0.574
LIG_LIR_Apic_2 787 791 PF02991 0.574
LIG_LIR_Gen_1 293 303 PF02991 0.404
LIG_LIR_Gen_1 309 318 PF02991 0.433
LIG_LIR_Gen_1 32 42 PF02991 0.545
LIG_LIR_Gen_1 610 620 PF02991 0.401
LIG_LIR_Gen_1 623 634 PF02991 0.399
LIG_LIR_Gen_1 639 647 PF02991 0.293
LIG_LIR_Gen_1 769 778 PF02991 0.571
LIG_LIR_Gen_1 795 800 PF02991 0.555
LIG_LIR_Nem_3 120 124 PF02991 0.442
LIG_LIR_Nem_3 230 235 PF02991 0.419
LIG_LIR_Nem_3 309 314 PF02991 0.446
LIG_LIR_Nem_3 32 37 PF02991 0.543
LIG_LIR_Nem_3 47 53 PF02991 0.485
LIG_LIR_Nem_3 597 603 PF02991 0.357
LIG_LIR_Nem_3 610 615 PF02991 0.394
LIG_LIR_Nem_3 623 629 PF02991 0.404
LIG_LIR_Nem_3 639 645 PF02991 0.296
LIG_LIR_Nem_3 649 655 PF02991 0.406
LIG_LIR_Nem_3 699 704 PF02991 0.516
LIG_LIR_Nem_3 736 742 PF02991 0.519
LIG_LIR_Nem_3 756 762 PF02991 0.322
LIG_LIR_Nem_3 769 773 PF02991 0.568
LIG_LIR_Nem_3 795 799 PF02991 0.561
LIG_MLH1_MIPbox_1 379 383 PF16413 0.459
LIG_NRBOX 158 164 PF00104 0.402
LIG_NRBOX 458 464 PF00104 0.477
LIG_Pex14_1 270 274 PF04695 0.438
LIG_Pex14_1 591 595 PF04695 0.383
LIG_Pex14_1 622 626 PF04695 0.400
LIG_Pex14_1 755 759 PF04695 0.497
LIG_Pex14_2 311 315 PF04695 0.421
LIG_Pex14_2 751 755 PF04695 0.501
LIG_PTB_Apo_2 382 389 PF02174 0.402
LIG_PTB_Apo_2 56 63 PF02174 0.592
LIG_PTB_Phospho_1 56 62 PF10480 0.587
LIG_REV1ctd_RIR_1 312 321 PF16727 0.465
LIG_SH2_CRK 626 630 PF00017 0.454
LIG_SH2_CRK 642 646 PF00017 0.339
LIG_SH2_CRK 723 727 PF00017 0.580
LIG_SH2_CRK 770 774 PF00017 0.581
LIG_SH2_GRB2like 480 483 PF00017 0.509
LIG_SH2_GRB2like 57 60 PF00017 0.571
LIG_SH2_NCK_1 626 630 PF00017 0.460
LIG_SH2_NCK_1 770 774 PF00017 0.581
LIG_SH2_SRC 215 218 PF00017 0.368
LIG_SH2_SRC 529 532 PF00017 0.619
LIG_SH2_SRC 62 65 PF00017 0.551
LIG_SH2_SRC 642 645 PF00017 0.566
LIG_SH2_SRC 723 726 PF00017 0.591
LIG_SH2_STAP1 109 113 PF00017 0.468
LIG_SH2_STAP1 480 484 PF00017 0.503
LIG_SH2_STAP1 735 739 PF00017 0.523
LIG_SH2_STAP1 770 774 PF00017 0.581
LIG_SH2_STAP1 88 92 PF00017 0.531
LIG_SH2_STAT3 113 116 PF00017 0.462
LIG_SH2_STAT3 119 122 PF00017 0.431
LIG_SH2_STAT3 346 349 PF00017 0.630
LIG_SH2_STAT3 480 483 PF00017 0.509
LIG_SH2_STAT5 113 116 PF00017 0.462
LIG_SH2_STAT5 124 127 PF00017 0.455
LIG_SH2_STAT5 177 180 PF00017 0.409
LIG_SH2_STAT5 215 218 PF00017 0.368
LIG_SH2_STAT5 235 238 PF00017 0.223
LIG_SH2_STAT5 266 269 PF00017 0.480
LIG_SH2_STAT5 295 298 PF00017 0.408
LIG_SH2_STAT5 505 508 PF00017 0.400
LIG_SH2_STAT5 527 530 PF00017 0.528
LIG_SH2_STAT5 580 583 PF00017 0.379
LIG_SH2_STAT5 683 686 PF00017 0.450
LIG_SH2_STAT5 735 738 PF00017 0.532
LIG_SH3_2 713 718 PF14604 0.576
LIG_SH3_3 326 332 PF00018 0.484
LIG_SH3_3 335 341 PF00018 0.529
LIG_SH3_3 707 713 PF00018 0.596
LIG_SH3_3 714 720 PF00018 0.554
LIG_SH3_3 742 748 PF00018 0.508
LIG_SH3_5 679 683 PF00018 0.467
LIG_SUMO_SIM_anti_2 395 401 PF11976 0.530
LIG_TRAF2_1 260 263 PF00917 0.467
LIG_TRAF2_1 427 430 PF00917 0.541
LIG_TYR_ITIM 48 53 PF00017 0.625
LIG_UBA3_1 264 272 PF00899 0.454
LIG_UBA3_1 442 449 PF00899 0.546
LIG_UBA3_1 86 94 PF00899 0.517
LIG_ULM_U2AF65_1 339 344 PF00076 0.583
MOD_CDC14_SPxK_1 355 358 PF00782 0.504
MOD_CDC14_SPxK_1 715 718 PF00782 0.555
MOD_CDK_SPxK_1 352 358 PF00069 0.506
MOD_CDK_SPxK_1 712 718 PF00069 0.572
MOD_CK1_1 44 50 PF00069 0.641
MOD_CK1_1 452 458 PF00069 0.447
MOD_CK1_1 77 83 PF00069 0.523
MOD_CK2_1 257 263 PF00069 0.470
MOD_CK2_1 306 312 PF00069 0.473
MOD_CK2_1 341 347 PF00069 0.560
MOD_CK2_1 424 430 PF00069 0.538
MOD_CK2_1 542 548 PF00069 0.489
MOD_CK2_1 648 654 PF00069 0.427
MOD_Cter_Amidation 783 786 PF01082 0.698
MOD_GlcNHglycan 186 189 PF01048 0.533
MOD_GlcNHglycan 31 34 PF01048 0.607
MOD_GlcNHglycan 472 475 PF01048 0.442
MOD_GlcNHglycan 514 518 PF01048 0.430
MOD_GlcNHglycan 542 545 PF01048 0.542
MOD_GlcNHglycan 548 552 PF01048 0.533
MOD_GlcNHglycan 557 560 PF01048 0.406
MOD_GlcNHglycan 807 810 PF01048 0.608
MOD_GSK3_1 180 187 PF00069 0.474
MOD_GSK3_1 202 209 PF00069 0.408
MOD_GSK3_1 302 309 PF00069 0.531
MOD_GSK3_1 348 355 PF00069 0.508
MOD_GSK3_1 377 384 PF00069 0.455
MOD_GSK3_1 409 416 PF00069 0.488
MOD_GSK3_1 424 431 PF00069 0.501
MOD_GSK3_1 445 452 PF00069 0.489
MOD_GSK3_1 453 460 PF00069 0.398
MOD_GSK3_1 483 490 PF00069 0.408
MOD_GSK3_1 521 528 PF00069 0.551
MOD_LATS_1 731 737 PF00433 0.518
MOD_N-GLC_1 288 293 PF02516 0.393
MOD_N-GLC_1 80 85 PF02516 0.533
MOD_NEK2_1 2 7 PF00069 0.650
MOD_NEK2_1 458 463 PF00069 0.419
MOD_NEK2_1 496 501 PF00069 0.513
MOD_NEK2_1 542 547 PF00069 0.489
MOD_NEK2_1 620 625 PF00069 0.430
MOD_NEK2_2 535 540 PF00069 0.544
MOD_NEK2_2 571 576 PF00069 0.429
MOD_PIKK_1 41 47 PF00454 0.620
MOD_PK_1 605 611 PF00069 0.516
MOD_PKA_1 487 493 PF00069 0.550
MOD_PKA_1 605 611 PF00069 0.363
MOD_PKA_1 789 795 PF00069 0.585
MOD_PKA_2 145 151 PF00069 0.500
MOD_PKA_2 2 8 PF00069 0.678
MOD_PKA_2 496 502 PF00069 0.498
MOD_PKA_2 533 539 PF00069 0.506
MOD_PKA_2 605 611 PF00069 0.363
MOD_Plk_1 223 229 PF00069 0.383
MOD_Plk_1 306 312 PF00069 0.484
MOD_Plk_1 513 519 PF00069 0.376
MOD_Plk_2-3 306 312 PF00069 0.484
MOD_Plk_4 2 8 PF00069 0.721
MOD_Plk_4 306 312 PF00069 0.518
MOD_Plk_4 458 464 PF00069 0.386
MOD_Plk_4 576 582 PF00069 0.421
MOD_Plk_4 86 92 PF00069 0.523
MOD_ProDKin_1 252 258 PF00069 0.578
MOD_ProDKin_1 322 328 PF00069 0.468
MOD_ProDKin_1 341 347 PF00069 0.469
MOD_ProDKin_1 352 358 PF00069 0.440
MOD_ProDKin_1 453 459 PF00069 0.439
MOD_ProDKin_1 712 718 PF00069 0.572
MOD_SUMO_rev_2 246 252 PF00179 0.474
MOD_SUMO_rev_2 444 450 PF00179 0.545
MOD_SUMO_rev_2 738 745 PF00179 0.544
TRG_DiLeu_BaEn_4 262 268 PF01217 0.473
TRG_DiLeu_BaLyEn_6 454 459 PF01217 0.438
TRG_DiLeu_BaLyEn_6 633 638 PF01217 0.428
TRG_DiLeu_BaLyEn_6 64 69 PF01217 0.536
TRG_ENDOCYTIC_2 124 127 PF00928 0.455
TRG_ENDOCYTIC_2 215 218 PF00928 0.368
TRG_ENDOCYTIC_2 295 298 PF00928 0.408
TRG_ENDOCYTIC_2 50 53 PF00928 0.563
TRG_ENDOCYTIC_2 505 508 PF00928 0.376
TRG_ENDOCYTIC_2 626 629 PF00928 0.488
TRG_ENDOCYTIC_2 642 645 PF00928 0.315
TRG_ENDOCYTIC_2 701 704 PF00928 0.529
TRG_ENDOCYTIC_2 770 773 PF00928 0.578
TRG_ENDOCYTIC_2 796 799 PF00928 0.598
TRG_ER_diArg_1 338 340 PF00400 0.545
TRG_ER_diArg_1 465 467 PF00400 0.487
TRG_ER_diArg_1 603 606 PF00400 0.394
TRG_NES_CRM1_1 157 168 PF08389 0.402
TRG_NLS_MonoExtN_4 93 98 PF00514 0.512
TRG_Pf-PMV_PEXEL_1 164 168 PF00026 0.403
TRG_Pf-PMV_PEXEL_1 182 186 PF00026 0.415
TRG_Pf-PMV_PEXEL_1 475 479 PF00026 0.557
TRG_Pf-PMV_PEXEL_1 635 639 PF00026 0.408

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3E7 Leptomonas seymouri 87% 100%
A0A0S4J0S5 Bodo saltans 63% 100%
A4HDE1 Leishmania braziliensis 94% 100%
A4I0S2 Leishmania infantum 100% 100%
D0A752 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 77% 100%
E9AWS4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4QAQ0 Leishmania major 98% 100%
V5DSH5 Trypanosoma cruzi 77% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS