Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IEJ9_LEIDO

TriTrypDb:

LdBPK_303680.1 , LdCL_300042200 , LDHU3_30.4900

Length:

370

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IEJ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEJ9

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	13	17	PF00082	0.688
CLV_PCSK_SKI1_1	55	59	PF00082	0.767
CLV_PCSK_SKI1_1	72	76	PF00082	0.566
DEG_APCC_DBOX_1	225	233	PF00400	0.768
DEG_COP1_1	264	273	PF00400	0.552
DEG_Nend_UBRbox_2	1	3	PF02207	0.631
DOC_CKS1_1	288	293	PF01111	0.757
DOC_CKS1_1	294	299	PF01111	0.647
DOC_CYCLIN_yCln2_LP_2	294	300	PF00134	0.747
DOC_MAPK_gen_1	22	30	PF00069	0.639

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGN6	Leptomonas seymouri	55%	98%
A0A422NME0	Trypanosoma rangeli	29%	99%
A4HIU8	Leishmania braziliensis	75%	98%
A4I653	Leishmania infantum	100%	100%
C9ZRH3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	96%
E9B1D6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q6S6	Leishmania major	94%	100%
V5BX10	Trypanosoma cruzi	26%	99%

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