Neogenin_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IEI3_LEIDO

TriTrypDb:

LdBPK_280800.1 , LdCL_280012600 , LDHU3_28.0970

Length:

222

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IEI3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEI3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	95	99	PF00656	0.662
CLV_NRD_NRD_1	187	189	PF00675	0.490
CLV_PCSK_KEX2_1	187	189	PF00082	0.493
CLV_PCSK_SKI1_1	150	154	PF00082	0.567
CLV_PCSK_SKI1_1	178	182	PF00082	0.482
DOC_CYCLIN_RxL_1	174	185	PF00134	0.457
DOC_MAPK_MEF2A_6	213	222	PF00069	0.682
DOC_MAPK_MEF2A_6	29	36	PF00069	0.629
DOC_PP4_FxxP_1	28	31	PF00568	0.542
DOC_USP7_MATH_1	102	106	PF00917	0.743
DOC_WW_Pin1_4	104	109	PF00397	0.610
DOC_WW_Pin1_4	7	12	PF00397	0.583
DOC_WW_Pin1_4	97	102	PF00397	0.641
LIG_14-3-3_CanoR_1	104	108	PF00244	0.531
LIG_14-3-3_CanoR_1	213	219	PF00244	0.526
LIG_14-3-3_CanoR_1	3	8	PF00244	0.675
LIG_14-3-3_CanoR_1	89	97	PF00244	0.682
LIG_Actin_WH2_2	90	106	PF00022	0.648
LIG_BIR_II_1	1	5	PF00653	0.584
LIG_BRCT_BRCA1_1	106	110	PF00533	0.620
LIG_FAT_LD_1	197	205	PF03623	0.502
LIG_FHA_2	61	67	PF00498	0.667
LIG_LIR_Apic_2	25	31	PF02991	0.438
LIG_LIR_Apic_2	5	11	PF02991	0.569
LIG_MYND_1	11	15	PF01753	0.572
LIG_MYND_1	71	75	PF01753	0.561
LIG_PDZ_Class_2	217	222	PF00595	0.553
LIG_PTAP_UEV_1	14	19	PF05743	0.629
LIG_SH2_CRK	116	120	PF00017	0.599
LIG_SH2_PTP2	8	11	PF00017	0.573
LIG_SH2_STAP1	111	115	PF00017	0.743
LIG_SH2_STAT5	111	114	PF00017	0.605
LIG_SH2_STAT5	8	11	PF00017	0.573
LIG_SH3_3	12	18	PF00018	0.569
LIG_SH3_3	24	30	PF00018	0.566
LIG_SH3_3	71	77	PF00018	0.638
LIG_WW_1	108	111	PF00397	0.602
LIG_WW_1	52	55	PF00397	0.632
MOD_CDK_SPxxK_3	97	104	PF00069	0.637
MOD_CK1_1	139	145	PF00069	0.722
MOD_CK1_1	2	8	PF00069	0.578
MOD_CK2_1	60	66	PF00069	0.791
MOD_DYRK1A_RPxSP_1	104	108	PF00069	0.625
MOD_GlcNHglycan	138	141	PF01048	0.621
MOD_GlcNHglycan	38	41	PF01048	0.635
MOD_GlcNHglycan	55	58	PF01048	0.650
MOD_GSK3_1	214	221	PF00069	0.532
MOD_GSK3_1	3	10	PF00069	0.617
MOD_GSK3_1	32	39	PF00069	0.624
MOD_GSK3_1	88	95	PF00069	0.738
MOD_NEK2_1	1	6	PF00069	0.628
MOD_NEK2_1	103	108	PF00069	0.626
MOD_NEK2_1	214	219	PF00069	0.528
MOD_PIKK_1	109	115	PF00454	0.608
MOD_PIKK_1	187	193	PF00454	0.511
MOD_PKA_1	169	175	PF00069	0.524
MOD_PKA_1	187	193	PF00069	0.511
MOD_PKA_2	103	109	PF00069	0.478
MOD_PKA_2	187	193	PF00069	0.511
MOD_PKA_2	2	8	PF00069	0.674
MOD_PKA_2	88	94	PF00069	0.649
MOD_Plk_4	119	125	PF00069	0.611
MOD_Plk_4	3	9	PF00069	0.678
MOD_ProDKin_1	104	110	PF00069	0.613
MOD_ProDKin_1	7	13	PF00069	0.584
MOD_ProDKin_1	97	103	PF00069	0.639
MOD_SUMO_for_1	168	171	PF00179	0.536
TRG_DiLeu_BaEn_2	161	167	PF01217	0.535
TRG_DiLeu_BaEn_4	162	168	PF01217	0.537
TRG_ENDOCYTIC_2	116	119	PF00928	0.603
TRG_ER_diArg_1	186	188	PF00400	0.453
TRG_NES_CRM1_1	193	206	PF08389	0.504
TRG_Pf-PMV_PEXEL_1	174	179	PF00026	0.467

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I075	Leptomonas seymouri	61%	100%
A0A1X0NYH0	Trypanosomatidae	27%	100%
A4I3F0	Leishmania infantum	99%	100%