Dpy-30 motif containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IEH6_LEIDO

TriTrypDb:

LdBPK_271870.1 , LdCL_270025900 , LDHU3_27.2850

Length:

1521

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3Q8IEH6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006793	phosphorus metabolic process	3	1
GO:0006796	phosphate-containing compound metabolic process	4	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016310	phosphorylation	5	1
GO:0044237	cellular metabolic process	2	1

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004017	adenylate kinase activity	6	7
GO:0004127	cytidylate kinase activity	6	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1200	1204	PF00656	0.652
CLV_C14_Caspase3-7	1205	1209	PF00656	0.620
CLV_C14_Caspase3-7	1373	1377	PF00656	0.576
CLV_C14_Caspase3-7	1420	1424	PF00656	0.604
CLV_C14_Caspase3-7	1507	1511	PF00656	0.619
CLV_C14_Caspase3-7	223	227	PF00656	0.611
CLV_C14_Caspase3-7	233	237	PF00656	0.714
CLV_C14_Caspase3-7	863	867	PF00656	0.790
CLV_C14_Caspase3-7	997	1001	PF00656	0.696
CLV_MEL_PAP_1	407	413	PF00089	0.577

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5J1	Leptomonas seymouri	47%	95%
A4HFX0	Leishmania braziliensis	74%	99%
E9ADH5	Leishmania major	90%	99%
E9AHG1	Leishmania infantum	99%	100%
E9AZ99	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%

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