LeishMANIAdb
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RNA binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RNA binding protein, putative
Gene product:
RNA binding protein, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IEF2_LEIDO
TriTrypDb:
LdBPK_291500.1 * , LdCL_290020500 , LDHU3_29.2190
Length:
782

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0032991 protein-containing complex 1 1
GO:1990904 ribonucleoprotein complex 2 1

Expansion

Sequence features

A0A3Q8IEF2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEF2

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 6
GO:0003723 RNA binding 4 6
GO:0005488 binding 1 6
GO:0097159 organic cyclic compound binding 2 6
GO:1901363 heterocyclic compound binding 2 6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 109 113 PF00656 0.580
CLV_C14_Caspase3-7 149 153 PF00656 0.552
CLV_NRD_NRD_1 197 199 PF00675 0.534
CLV_NRD_NRD_1 246 248 PF00675 0.768
CLV_NRD_NRD_1 324 326 PF00675 0.633
CLV_NRD_NRD_1 445 447 PF00675 0.827
CLV_NRD_NRD_1 661 663 PF00675 0.814
CLV_PCSK_FUR_1 244 248 PF00082 0.764
CLV_PCSK_KEX2_1 246 248 PF00082 0.768
CLV_PCSK_KEX2_1 324 326 PF00082 0.633
CLV_PCSK_KEX2_1 445 447 PF00082 0.691
CLV_PCSK_KEX2_1 661 663 PF00082 0.814
CLV_PCSK_SKI1_1 129 133 PF00082 0.435
CLV_PCSK_SKI1_1 151 155 PF00082 0.435
CLV_PCSK_SKI1_1 157 161 PF00082 0.499
CLV_PCSK_SKI1_1 198 202 PF00082 0.495
CLV_PCSK_SKI1_1 246 250 PF00082 0.770
CLV_PCSK_SKI1_1 99 103 PF00082 0.530
DEG_SCF_FBW7_1 424 430 PF00400 0.647
DEG_SPOP_SBC_1 516 520 PF00917 0.768
DEG_SPOP_SBC_1 622 626 PF00917 0.752
DOC_CKS1_1 168 173 PF01111 0.705
DOC_CKS1_1 424 429 PF01111 0.743
DOC_CKS1_1 466 471 PF01111 0.830
DOC_CKS1_1 546 551 PF01111 0.739
DOC_MAPK_DCC_7 493 503 PF00069 0.840
DOC_MAPK_gen_1 155 164 PF00069 0.694
DOC_PP4_FxxP_1 439 442 PF00568 0.758
DOC_PP4_FxxP_1 691 694 PF00568 0.562
DOC_USP7_MATH_1 124 128 PF00917 0.580
DOC_USP7_MATH_1 24 28 PF00917 0.823
DOC_USP7_MATH_1 262 266 PF00917 0.859
DOC_USP7_MATH_1 301 305 PF00917 0.654
DOC_USP7_MATH_1 355 359 PF00917 0.812
DOC_USP7_MATH_1 505 509 PF00917 0.833
DOC_USP7_MATH_1 521 525 PF00917 0.564
DOC_USP7_MATH_1 537 541 PF00917 0.578
DOC_USP7_MATH_1 622 626 PF00917 0.803
DOC_USP7_MATH_1 696 700 PF00917 0.659
DOC_USP7_MATH_1 773 777 PF00917 0.676
DOC_USP7_MATH_1 94 98 PF00917 0.646
DOC_WW_Pin1_4 164 169 PF00397 0.725
DOC_WW_Pin1_4 20 25 PF00397 0.832
DOC_WW_Pin1_4 238 243 PF00397 0.772
DOC_WW_Pin1_4 249 254 PF00397 0.699
DOC_WW_Pin1_4 297 302 PF00397 0.639
DOC_WW_Pin1_4 359 364 PF00397 0.807
DOC_WW_Pin1_4 423 428 PF00397 0.723
DOC_WW_Pin1_4 453 458 PF00397 0.795
DOC_WW_Pin1_4 465 470 PF00397 0.681
DOC_WW_Pin1_4 477 482 PF00397 0.642
DOC_WW_Pin1_4 517 522 PF00397 0.796
DOC_WW_Pin1_4 533 538 PF00397 0.645
DOC_WW_Pin1_4 541 546 PF00397 0.674
DOC_WW_Pin1_4 551 556 PF00397 0.593
DOC_WW_Pin1_4 571 576 PF00397 0.549
DOC_WW_Pin1_4 683 688 PF00397 0.664
DOC_WW_Pin1_4 726 731 PF00397 0.715
DOC_WW_Pin1_4 745 750 PF00397 0.588
DOC_WW_Pin1_4 774 779 PF00397 0.791
LIG_14-3-3_CanoR_1 163 168 PF00244 0.729
LIG_14-3-3_CanoR_1 208 216 PF00244 0.532
LIG_14-3-3_CanoR_1 372 376 PF00244 0.741
LIG_14-3-3_CanoR_1 445 449 PF00244 0.748
LIG_14-3-3_CanoR_1 767 773 PF00244 0.722
LIG_APCC_ABBA_1 227 232 PF00400 0.639
LIG_BIR_III_2 235 239 PF00653 0.714
LIG_CaM_IQ_9 207 222 PF13499 0.503
LIG_eIF4E_1 411 417 PF01652 0.524
LIG_FHA_1 140 146 PF00498 0.636
LIG_FHA_1 3 9 PF00498 0.784
LIG_FHA_1 33 39 PF00498 0.811
LIG_FHA_1 363 369 PF00498 0.700
LIG_FHA_1 412 418 PF00498 0.556
LIG_FHA_1 490 496 PF00498 0.718
LIG_FHA_1 572 578 PF00498 0.721
LIG_FHA_1 769 775 PF00498 0.721
LIG_FHA_2 107 113 PF00498 0.636
LIG_FHA_2 208 214 PF00498 0.622
LIG_FHA_2 255 261 PF00498 0.775
LIG_FHA_2 267 273 PF00498 0.610
LIG_FHA_2 280 286 PF00498 0.501
LIG_FHA_2 298 304 PF00498 0.358
LIG_IBAR_NPY_1 762 764 PF08397 0.783
LIG_LIR_Apic_2 606 612 PF02991 0.724
LIG_LIR_Gen_1 117 126 PF02991 0.636
LIG_LIR_Gen_1 141 150 PF02991 0.547
LIG_LIR_Gen_1 72 80 PF02991 0.635
LIG_LIR_Nem_3 117 122 PF02991 0.577
LIG_LIR_Nem_3 141 147 PF02991 0.539
LIG_LIR_Nem_3 219 224 PF02991 0.614
LIG_LIR_Nem_3 602 607 PF02991 0.810
LIG_LIR_Nem_3 72 76 PF02991 0.627
LIG_LYPXL_SIV_4 696 704 PF13949 0.707
LIG_MYND_1 683 687 PF01753 0.726
LIG_Pex14_2 217 221 PF04695 0.610
LIG_PTAP_UEV_1 480 485 PF05743 0.722
LIG_PTB_Apo_2 758 765 PF02174 0.800
LIG_PTB_Phospho_1 758 764 PF10480 0.803
LIG_REV1ctd_RIR_1 157 167 PF16727 0.657
LIG_SH2_CRK 370 374 PF00017 0.668
LIG_SH2_CRK 391 395 PF00017 0.646
LIG_SH2_GRB2like 411 414 PF00017 0.701
LIG_SH2_NCK_1 234 238 PF00017 0.698
LIG_SH2_NCK_1 352 356 PF00017 0.743
LIG_SH2_NCK_1 391 395 PF00017 0.744
LIG_SH2_NCK_1 697 701 PF00017 0.705
LIG_SH2_STAP1 352 356 PF00017 0.801
LIG_SH2_STAP1 672 676 PF00017 0.645
LIG_SH2_STAP1 764 768 PF00017 0.792
LIG_SH2_STAT3 420 423 PF00017 0.785
LIG_SH2_STAT3 429 432 PF00017 0.732
LIG_SH2_STAT5 411 414 PF00017 0.768
LIG_SH2_STAT5 569 572 PF00017 0.676
LIG_SH2_STAT5 576 579 PF00017 0.696
LIG_SH2_STAT5 731 734 PF00017 0.677
LIG_SH3_1 421 427 PF00018 0.742
LIG_SH3_1 493 499 PF00018 0.760
LIG_SH3_1 609 615 PF00018 0.623
LIG_SH3_3 165 171 PF00018 0.593
LIG_SH3_3 370 376 PF00018 0.646
LIG_SH3_3 395 401 PF00018 0.728
LIG_SH3_3 421 427 PF00018 0.804
LIG_SH3_3 463 469 PF00018 0.829
LIG_SH3_3 478 484 PF00018 0.753
LIG_SH3_3 492 498 PF00018 0.651
LIG_SH3_3 510 516 PF00018 0.596
LIG_SH3_3 520 526 PF00018 0.624
LIG_SH3_3 543 549 PF00018 0.832
LIG_SH3_3 609 615 PF00018 0.662
LIG_SH3_3 673 679 PF00018 0.628
LIG_SH3_3 724 730 PF00018 0.799
LIG_SUMO_SIM_par_1 770 777 PF11976 0.719
LIG_TRFH_1 731 735 PF08558 0.672
LIG_TYR_ITIM 368 373 PF00017 0.748
LIG_WRC_WIRS_1 280 285 PF05994 0.597
LIG_WRC_WIRS_1 538 543 PF05994 0.674
MOD_CDC14_SPxK_1 241 244 PF00782 0.653
MOD_CDK_SPK_2 423 428 PF00069 0.606
MOD_CDK_SPK_2 545 550 PF00069 0.665
MOD_CDK_SPxK_1 238 244 PF00069 0.648
MOD_CDK_SPxK_1 533 539 PF00069 0.753
MOD_CDK_SPxxK_3 545 552 PF00069 0.774
MOD_CK1_1 139 145 PF00069 0.636
MOD_CK1_1 166 172 PF00069 0.754
MOD_CK1_1 225 231 PF00069 0.489
MOD_CK1_1 254 260 PF00069 0.766
MOD_CK1_1 27 33 PF00069 0.805
MOD_CK1_1 350 356 PF00069 0.764
MOD_CK1_1 374 380 PF00069 0.744
MOD_CK1_1 392 398 PF00069 0.791
MOD_CK1_1 422 428 PF00069 0.788
MOD_CK1_1 430 436 PF00069 0.733
MOD_CK1_1 456 462 PF00069 0.757
MOD_CK1_1 46 52 PF00069 0.516
MOD_CK1_1 465 471 PF00069 0.670
MOD_CK1_1 473 479 PF00069 0.607
MOD_CK1_1 489 495 PF00069 0.598
MOD_CK1_1 508 514 PF00069 0.572
MOD_CK1_1 54 60 PF00069 0.683
MOD_CK1_1 554 560 PF00069 0.769
MOD_CK1_1 625 631 PF00069 0.826
MOD_CK1_1 641 647 PF00069 0.527
MOD_CK1_1 725 731 PF00069 0.692
MOD_CK1_1 744 750 PF00069 0.683
MOD_CK1_1 751 757 PF00069 0.751
MOD_CK2_1 207 213 PF00069 0.415
MOD_CK2_1 249 255 PF00069 0.806
MOD_CK2_1 264 270 PF00069 0.513
MOD_CK2_1 279 285 PF00069 0.412
MOD_CK2_1 44 50 PF00069 0.757
MOD_CK2_1 537 543 PF00069 0.664
MOD_CK2_1 78 84 PF00069 0.640
MOD_Cter_Amidation 244 247 PF01082 0.765
MOD_GlcNHglycan 126 129 PF01048 0.435
MOD_GlcNHglycan 266 269 PF01048 0.632
MOD_GlcNHglycan 29 32 PF01048 0.781
MOD_GlcNHglycan 353 356 PF01048 0.793
MOD_GlcNHglycan 391 394 PF01048 0.706
MOD_GlcNHglycan 407 410 PF01048 0.810
MOD_GlcNHglycan 432 435 PF01048 0.802
MOD_GlcNHglycan 451 454 PF01048 0.534
MOD_GlcNHglycan 458 461 PF01048 0.688
MOD_GlcNHglycan 507 510 PF01048 0.723
MOD_GlcNHglycan 55 59 PF01048 0.817
MOD_GlcNHglycan 556 559 PF01048 0.841
MOD_GlcNHglycan 625 628 PF01048 0.730
MOD_GlcNHglycan 642 646 PF01048 0.543
MOD_GlcNHglycan 66 69 PF01048 0.686
MOD_GlcNHglycan 672 675 PF01048 0.759
MOD_GlcNHglycan 698 701 PF01048 0.662
MOD_GlcNHglycan 724 727 PF01048 0.811
MOD_GlcNHglycan 741 744 PF01048 0.538
MOD_GlcNHglycan 750 753 PF01048 0.691
MOD_GSK3_1 163 170 PF00069 0.732
MOD_GSK3_1 20 27 PF00069 0.760
MOD_GSK3_1 262 269 PF00069 0.816
MOD_GSK3_1 297 304 PF00069 0.516
MOD_GSK3_1 327 334 PF00069 0.580
MOD_GSK3_1 346 353 PF00069 0.683
MOD_GSK3_1 355 362 PF00069 0.666
MOD_GSK3_1 37 44 PF00069 0.539
MOD_GSK3_1 407 414 PF00069 0.666
MOD_GSK3_1 419 426 PF00069 0.712
MOD_GSK3_1 449 456 PF00069 0.733
MOD_GSK3_1 470 477 PF00069 0.825
MOD_GSK3_1 499 506 PF00069 0.836
MOD_GSK3_1 517 524 PF00069 0.540
MOD_GSK3_1 533 540 PF00069 0.610
MOD_GSK3_1 541 548 PF00069 0.756
MOD_GSK3_1 563 570 PF00069 0.773
MOD_GSK3_1 621 628 PF00069 0.828
MOD_GSK3_1 666 673 PF00069 0.698
MOD_GSK3_1 722 729 PF00069 0.665
MOD_GSK3_1 739 746 PF00069 0.678
MOD_GSK3_1 747 754 PF00069 0.709
MOD_N-GLC_1 222 227 PF02516 0.492
MOD_N-GLC_1 297 302 PF02516 0.639
MOD_N-GLC_1 317 322 PF02516 0.434
MOD_N-GLC_1 44 49 PF02516 0.757
MOD_N-GLC_2 651 653 PF02516 0.621
MOD_N-GLC_2 7 9 PF02516 0.752
MOD_NEK2_1 407 412 PF00069 0.717
MOD_NEK2_1 43 48 PF00069 0.794
MOD_NEK2_1 475 480 PF00069 0.763
MOD_NEK2_1 53 58 PF00069 0.694
MOD_NEK2_1 556 561 PF00069 0.624
MOD_NEK2_1 565 570 PF00069 0.580
MOD_NEK2_1 768 773 PF00069 0.723
MOD_NEK2_2 537 542 PF00069 0.662
MOD_PIKK_1 175 181 PF00454 0.650
MOD_PIKK_1 207 213 PF00454 0.629
MOD_PIKK_1 216 222 PF00454 0.432
MOD_PIKK_1 374 380 PF00454 0.822
MOD_PIKK_1 419 425 PF00454 0.778
MOD_PIKK_1 428 434 PF00454 0.730
MOD_PIKK_1 556 562 PF00454 0.760
MOD_PIKK_1 717 723 PF00454 0.642
MOD_PIKK_1 741 747 PF00454 0.725
MOD_PKA_2 207 213 PF00069 0.512
MOD_PKA_2 371 377 PF00069 0.742
MOD_PKA_2 444 450 PF00069 0.748
MOD_PKB_1 161 169 PF00069 0.713
MOD_Plk_1 225 231 PF00069 0.610
MOD_Plk_1 44 50 PF00069 0.757
MOD_Plk_1 605 611 PF00069 0.763
MOD_Plk_1 641 647 PF00069 0.728
MOD_Plk_4 273 279 PF00069 0.520
MOD_Plk_4 407 413 PF00069 0.634
MOD_Plk_4 462 468 PF00069 0.796
MOD_Plk_4 470 476 PF00069 0.730
MOD_ProDKin_1 164 170 PF00069 0.724
MOD_ProDKin_1 20 26 PF00069 0.831
MOD_ProDKin_1 238 244 PF00069 0.776
MOD_ProDKin_1 249 255 PF00069 0.701
MOD_ProDKin_1 297 303 PF00069 0.649
MOD_ProDKin_1 359 365 PF00069 0.809
MOD_ProDKin_1 423 429 PF00069 0.727
MOD_ProDKin_1 453 459 PF00069 0.796
MOD_ProDKin_1 465 471 PF00069 0.679
MOD_ProDKin_1 477 483 PF00069 0.641
MOD_ProDKin_1 517 523 PF00069 0.791
MOD_ProDKin_1 533 539 PF00069 0.649
MOD_ProDKin_1 541 547 PF00069 0.677
MOD_ProDKin_1 551 557 PF00069 0.592
MOD_ProDKin_1 571 577 PF00069 0.549
MOD_ProDKin_1 683 689 PF00069 0.665
MOD_ProDKin_1 726 732 PF00069 0.716
MOD_ProDKin_1 745 751 PF00069 0.589
MOD_ProDKin_1 774 780 PF00069 0.793
TRG_DiLeu_BaEn_2 212 218 PF01217 0.404
TRG_DiLeu_BaEn_3 272 278 PF01217 0.600
TRG_ENDOCYTIC_2 370 373 PF00928 0.715
TRG_ENDOCYTIC_2 391 394 PF00928 0.648
TRG_ER_diArg_1 154 157 PF00400 0.636
TRG_ER_diArg_1 160 163 PF00400 0.541
TRG_ER_diArg_1 244 247 PF00400 0.765
TRG_ER_diArg_1 444 446 PF00400 0.825
TRG_ER_diArg_1 490 493 PF00400 0.821
TRG_ER_diArg_1 549 552 PF00400 0.777
TRG_ER_diArg_1 661 663 PF00400 0.814
TRG_Pf-PMV_PEXEL_1 246 250 PF00026 0.770

Homologs

Protein Taxonomy Sequence identity Coverage
A4HHE9 Leishmania braziliensis 64% 99%
A4I4J9 Leishmania infantum 99% 100%
E9ADZ8 Leishmania major 90% 99%
E9ALT3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS