Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IED4_LEIDO

TriTrypDb:

LdBPK_271690.1 , LdCL_270024000 , LDHU3_27.2610

Length:

841

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IED4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IED4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	251	255	PF00656	0.568
CLV_C14_Caspase3-7	437	441	PF00656	0.617
CLV_NRD_NRD_1	300	302	PF00675	0.585
CLV_NRD_NRD_1	331	333	PF00675	0.622
CLV_NRD_NRD_1	363	365	PF00675	0.627
CLV_NRD_NRD_1	406	408	PF00675	0.642
CLV_NRD_NRD_1	416	418	PF00675	0.569
CLV_NRD_NRD_1	462	464	PF00675	0.700
CLV_NRD_NRD_1	478	480	PF00675	0.510
CLV_NRD_NRD_1	508	510	PF00675	0.697

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P552	Leptomonas seymouri	37%	87%
A4HFV2	Leishmania braziliensis	69%	99%
A4I2Y5	Leishmania infantum	100%	100%
E9ADF6	Leishmania major	88%	100%
E9AZ79	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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