p25-alpha, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

p25-alpha, putative

Gene product:

p25-alpha, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IEB6_LEIDO

TriTrypDb:

LdBPK_341630.1 , LdCL_340022500 , LDHU3_34.2460

Length:

272

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IEB6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IEB6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	161	165	PF00656	0.633
CLV_C14_Caspase3-7	260	264	PF00656	0.523
CLV_MEL_PAP_1	49	55	PF00089	0.441
CLV_NRD_NRD_1	177	179	PF00675	0.427
CLV_NRD_NRD_1	257	259	PF00675	0.433
CLV_PCSK_KEX2_1	257	259	PF00082	0.433
CLV_PCSK_SKI1_1	148	152	PF00082	0.437
CLV_PCSK_SKI1_1	158	162	PF00082	0.316
DEG_Nend_UBRbox_3	1	3	PF02207	0.443
DOC_CDC14_PxL_1	20	28	PF14671	0.427
DOC_CKS1_1	6	11	PF01111	0.434
DOC_MAPK_gen_1	173	182	PF00069	0.633
DOC_MAPK_MEF2A_6	44	53	PF00069	0.450
DOC_PP1_RVXF_1	176	183	PF00149	0.633
DOC_PP2B_LxvP_1	21	24	PF13499	0.593
DOC_PP2B_LxvP_1	26	29	PF13499	0.408
DOC_PP4_FxxP_1	87	90	PF00568	0.409
DOC_USP7_MATH_1	129	133	PF00917	0.616
DOC_USP7_MATH_1	213	217	PF00917	0.516
DOC_USP7_MATH_1	45	49	PF00917	0.465
DOC_USP7_MATH_1	67	71	PF00917	0.437
DOC_USP7_MATH_1	9	13	PF00917	0.437
DOC_USP7_UBL2_3	154	158	PF12436	0.633
DOC_USP7_UBL2_3	171	175	PF12436	0.434
DOC_WW_Pin1_4	107	112	PF00397	0.422
DOC_WW_Pin1_4	197	202	PF00397	0.633
DOC_WW_Pin1_4	5	10	PF00397	0.428
DOC_WW_Pin1_4	51	56	PF00397	0.438
DOC_WW_Pin1_4	80	85	PF00397	0.476
DOC_WW_Pin1_4	86	91	PF00397	0.406
LIG_14-3-3_CanoR_1	103	109	PF00244	0.418
LIG_14-3-3_CanoR_1	178	183	PF00244	0.633
LIG_14-3-3_CanoR_1	265	272	PF00244	0.755
LIG_14-3-3_CanoR_1	68	72	PF00244	0.446
LIG_14-3-3_CanoR_1	95	99	PF00244	0.431
LIG_FHA_1	94	100	PF00498	0.433
LIG_FHA_2	159	165	PF00498	0.633
LIG_FHA_2	198	204	PF00498	0.633
LIG_FHA_2	216	222	PF00498	0.423
LIG_FHA_2	240	246	PF00498	0.633
LIG_LIR_Apic_2	4	9	PF02991	0.424
LIG_LIR_Gen_1	126	133	PF02991	0.608
LIG_LIR_Gen_1	144	150	PF02991	0.483
LIG_LIR_Gen_1	166	177	PF02991	0.633
LIG_LIR_Gen_1	181	190	PF02991	0.458
LIG_LIR_Gen_1	8	17	PF02991	0.432
LIG_LIR_Nem_3	126	130	PF02991	0.583
LIG_LIR_Nem_3	166	172	PF02991	0.633
LIG_LIR_Nem_3	181	185	PF02991	0.458
LIG_LIR_Nem_3	69	75	PF02991	0.442
LIG_LIR_Nem_3	8	13	PF02991	0.435
LIG_MYND_1	114	118	PF01753	0.426
LIG_Pex14_1	6	10	PF04695	0.430
LIG_Pex14_2	123	127	PF04695	0.433
LIG_Pex14_2	71	75	PF04695	0.443
LIG_Pex14_2	94	98	PF04695	0.436
LIG_PTB_Apo_2	140	147	PF02174	0.616
LIG_SH2_STAT5	106	109	PF00017	0.449
LIG_SH2_STAT5	232	235	PF00017	0.575
LIG_SH2_STAT5	86	89	PF00017	0.569
LIG_SH3_3	108	114	PF00018	0.424
LIG_SH3_3	32	38	PF00018	0.449
LIG_SH3_3	78	84	PF00018	0.589
LIG_WRC_WIRS_1	130	135	PF05994	0.616
MOD_CK1_1	109	115	PF00069	0.422
MOD_CK1_1	12	18	PF00069	0.432
MOD_CK1_1	132	138	PF00069	0.623
MOD_CK1_1	144	150	PF00069	0.503
MOD_CK1_1	159	165	PF00069	0.458
MOD_CK1_1	19	25	PF00069	0.415
MOD_CK1_1	215	221	PF00069	0.605
MOD_CK1_1	230	236	PF00069	0.446
MOD_CK2_1	178	184	PF00069	0.633
MOD_GlcNHglycan	100	103	PF01048	0.430
MOD_GlcNHglycan	134	137	PF01048	0.316
MOD_GlcNHglycan	215	218	PF01048	0.316
MOD_GlcNHglycan	3	6	PF01048	0.427
MOD_GSK3_1	1	8	PF00069	0.434
MOD_GSK3_1	12	19	PF00069	0.418
MOD_GSK3_1	156	163	PF00069	0.633
MOD_GSK3_1	215	222	PF00069	0.516
MOD_GSK3_1	94	101	PF00069	0.433
MOD_NEK2_1	1	6	PF00069	0.434
MOD_NEK2_1	104	109	PF00069	0.480
MOD_NEK2_1	141	146	PF00069	0.557
MOD_NEK2_1	167	172	PF00069	0.625
MOD_NEK2_1	94	99	PF00069	0.481
MOD_NEK2_2	67	72	PF00069	0.440
MOD_OFUCOSY	11	16	PF10250	0.433
MOD_PKA_1	178	184	PF00069	0.633
MOD_PKA_2	264	270	PF00069	0.566
MOD_PKA_2	67	73	PF00069	0.436
MOD_PKA_2	94	100	PF00069	0.433
MOD_Plk_1	141	147	PF00069	0.633
MOD_Plk_1	227	233	PF00069	0.633
MOD_Plk_4	16	22	PF00069	0.549
MOD_Plk_4	53	59	PF00069	0.435
MOD_Plk_4	67	73	PF00069	0.436
MOD_Plk_4	94	100	PF00069	0.433
MOD_ProDKin_1	107	113	PF00069	0.425
MOD_ProDKin_1	197	203	PF00069	0.633
MOD_ProDKin_1	5	11	PF00069	0.432
MOD_ProDKin_1	51	57	PF00069	0.438
MOD_ProDKin_1	80	86	PF00069	0.479
MOD_SUMO_rev_2	147	156	PF00179	0.633
MOD_SUMO_rev_2	221	231	PF00179	0.562
TRG_DiLeu_BaLyEn_6	21	26	PF01217	0.423
TRG_Pf-PMV_PEXEL_1	148	152	PF00026	0.433

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H7S1	Leishmania braziliensis	76%	100%