LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8IE75_LEIDO
TriTrypDb:
LdBPK_180600.1 * , LdCL_180010900 , LDHU3_18.0780
Length:
91

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IE75
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IE75

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 24 26 PF00675 0.544
CLV_NRD_NRD_1 67 69 PF00675 0.530
CLV_PCSK_KEX2_1 24 26 PF00082 0.544
CLV_PCSK_KEX2_1 66 68 PF00082 0.561
CLV_PCSK_SKI1_1 28 32 PF00082 0.633
CLV_PCSK_SKI1_1 73 77 PF00082 0.482
CLV_PCSK_SKI1_1 85 89 PF00082 0.460
DEG_APCC_DBOX_1 27 35 PF00400 0.521
DOC_CYCLIN_RxL_1 82 91 PF00134 0.510
DOC_MAPK_gen_1 24 35 PF00069 0.507
DOC_MAPK_MEF2A_6 28 35 PF00069 0.513
DOC_PP4_FxxP_1 7 10 PF00568 0.542
DOC_WW_Pin1_4 12 17 PF00397 0.543
DOC_WW_Pin1_4 54 59 PF00397 0.590
LIG_14-3-3_CanoR_1 25 31 PF00244 0.525
LIG_14-3-3_CanoR_1 73 81 PF00244 0.457
LIG_Actin_WH2_2 27 45 PF00022 0.472
LIG_BIR_II_1 1 5 PF00653 0.504
LIG_LIR_Gen_1 38 46 PF02991 0.519
LIG_LIR_Nem_3 38 42 PF02991 0.503
LIG_LIR_Nem_3 76 81 PF02991 0.475
LIG_SH3_1 13 19 PF00018 0.549
LIG_SH3_3 13 19 PF00018 0.542
LIG_SUMO_SIM_anti_2 29 35 PF11976 0.649
LIG_SUMO_SIM_par_1 32 38 PF11976 0.455
LIG_WRC_WIRS_1 36 41 PF05994 0.473
MOD_CDC14_SPxK_1 15 18 PF00782 0.547
MOD_CDK_SPK_2 54 59 PF00069 0.590
MOD_CDK_SPxK_1 12 18 PF00069 0.545
MOD_CK1_1 29 35 PF00069 0.518
MOD_CK2_1 42 48 PF00069 0.516
MOD_GlcNHglycan 44 47 PF01048 0.577
MOD_GSK3_1 5 12 PF00069 0.559
MOD_LATS_1 71 77 PF00433 0.477
MOD_NEK2_1 26 31 PF00069 0.493
MOD_NEK2_1 42 47 PF00069 0.454
MOD_NEK2_1 5 10 PF00069 0.540
MOD_OFUCOSY 3 9 PF10250 0.567
MOD_PKA_1 24 30 PF00069 0.520
MOD_PKA_2 24 30 PF00069 0.573
MOD_Plk_4 29 35 PF00069 0.506
MOD_ProDKin_1 12 18 PF00069 0.545
MOD_ProDKin_1 54 60 PF00069 0.589
TRG_ER_diArg_1 23 25 PF00400 0.545
TRG_ER_diArg_1 66 68 PF00400 0.541

Homologs

Protein Taxonomy Sequence identity Coverage
A4HXT5 Leishmania infantum 99% 100%
E9ARJ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 72%
Q4QDY2 Leishmania major 80% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS