LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IE74_LEIDO
TriTrypDb:
LdBPK_270410.1 , LdCL_270008900 , LDHU3_27.0490
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IE74
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IE74

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 111 113 PF00675 0.489
CLV_PCSK_KEX2_1 111 113 PF00082 0.498
CLV_PCSK_KEX2_1 120 122 PF00082 0.444
CLV_PCSK_PC1ET2_1 120 122 PF00082 0.501
CLV_PCSK_SKI1_1 37 41 PF00082 0.605
CLV_PCSK_SKI1_1 47 51 PF00082 0.536
DEG_MDM2_SWIB_1 9 16 PF02201 0.574
DEG_Nend_UBRbox_3 1 3 PF02207 0.603
DOC_MAPK_gen_1 92 100 PF00069 0.548
DOC_USP7_MATH_1 134 138 PF00917 0.588
DOC_USP7_MATH_1 82 86 PF00917 0.465
DOC_USP7_UBL2_3 83 87 PF12436 0.529
LIG_14-3-3_CanoR_1 23 31 PF00244 0.563
LIG_FHA_1 26 32 PF00498 0.528
LIG_FHA_1 38 44 PF00498 0.396
LIG_LIR_Gen_1 10 17 PF02991 0.503
LIG_LIR_Gen_1 59 68 PF02991 0.548
LIG_LIR_Nem_3 10 16 PF02991 0.531
LIG_LIR_Nem_3 59 64 PF02991 0.547
LIG_NRBOX 38 44 PF00104 0.541
LIG_Pex14_2 9 13 PF04695 0.503
LIG_RPA_C_Fungi 106 118 PF08784 0.540
LIG_SUMO_SIM_anti_2 38 43 PF11976 0.543
MOD_CK1_1 25 31 PF00069 0.628
MOD_CK1_1 3 9 PF00069 0.598
MOD_GlcNHglycan 24 27 PF01048 0.586
MOD_N-GLC_1 1 6 PF02516 0.616
MOD_NEK2_1 1 6 PF00069 0.655
MOD_NEK2_2 82 87 PF00069 0.548
MOD_PK_1 111 117 PF00069 0.493
MOD_PKA_1 111 117 PF00069 0.623
MOD_PKA_2 111 117 PF00069 0.623
MOD_PKA_2 22 28 PF00069 0.597
MOD_Plk_1 100 106 PF00069 0.471
MOD_Plk_1 37 43 PF00069 0.415
MOD_Plk_2-3 48 54 PF00069 0.550
MOD_Plk_2-3 56 62 PF00069 0.546
MOD_Plk_4 37 43 PF00069 0.516
TRG_DiLeu_BaEn_1 38 43 PF01217 0.543
TRG_DiLeu_BaEn_1 60 65 PF01217 0.545

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P666 Leptomonas seymouri 69% 99%
A0A1X0P462 Trypanosomatidae 36% 100%
A0A422NTD2 Trypanosoma rangeli 32% 100%
A4HFG4 Leishmania braziliensis 82% 100%
A4I2M6 Leishmania infantum 99% 100%
E9AD17 Leishmania major 95% 100%
E9AYU2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS