DUF2757 family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IE24_LEIDO

TriTrypDb:

LdBPK_211960.1 , LdCL_210025300 , LDHU3_21.2350

Length:

135


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

A0A3Q8IE24

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IE24


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	47	51	PF00656	0.753
CLV_NRD_NRD_1	102	104	PF00675	0.566
CLV_NRD_NRD_1	7	9	PF00675	0.496
CLV_PCSK_KEX2_1	104	106	PF00082	0.570
CLV_PCSK_KEX2_1	7	9	PF00082	0.496
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.607
CLV_PCSK_SKI1_1	8	12	PF00082	0.514
DEG_SPOP_SBC_1	42	46	PF00917	0.510
LIG_14-3-3_CanoR_1	15	20	PF00244	0.596
LIG_BIR_II_1	1	5	PF00653	0.636
LIG_BRCT_BRCA1_1	109	113	PF00533	0.578
LIG_DLG_GKlike_1	15	22	PF00625	0.594
LIG_FHA_1	116	122	PF00498	0.624
LIG_FHA_1	34	40	PF00498	0.569
LIG_FHA_2	114	120	PF00498	0.572
LIG_FHA_2	9	15	PF00498	0.636
LIG_LIR_Apic_2	81	87	PF02991	0.514
LIG_NRBOX	21	27	PF00104	0.514
LIG_SUMO_SIM_anti_2	18	24	PF11976	0.601
LIG_TRAF2_1	11	14	PF00917	0.593
LIG_WRC_WIRS_1	27	32	PF05994	0.509
MOD_CK2_1	8	14	PF00069	0.678
MOD_GlcNHglycan	1	4	PF01048	0.746
MOD_GSK3_1	107	114	PF00069	0.558
MOD_GSK3_1	41	48	PF00069	0.627
MOD_NEK2_1	1	6	PF00069	0.697
MOD_NEK2_1	111	116	PF00069	0.539
MOD_NEK2_1	25	30	PF00069	0.549
MOD_NEK2_1	88	93	PF00069	0.503
MOD_NEK2_2	98	103	PF00069	0.548
MOD_PIKK_1	1	7	PF00454	0.633
MOD_PKA_2	78	84	PF00069	0.653
MOD_PKA_2	98	104	PF00069	0.407
MOD_Plk_1	107	113	PF00069	0.522
MOD_Plk_1	53	59	PF00069	0.557
TRG_ER_diArg_1	102	105	PF00400	0.557
TRG_ER_diArg_1	57	60	PF00400	0.492
TRG_ER_diArg_1	7	9	PF00400	0.496
TRG_NLS_MonoExtC_3	102	108	PF00514	0.574
TRG_Pf-PMV_PEXEL_1	8	13	PF00026	0.514


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P421	Leptomonas seymouri	46%	89%
A4HC22	Leishmania braziliensis	69%	100%
A4HZG5	Leishmania infantum	97%	100%
E9AVF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QC24	Leishmania major	87%	100%