Short chain dehydrogenase/Enoyl-(Acyl carrier protein) reductase, putative

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

short chain dehydrogenase, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IE20_LEIDO

TriTrypDb:

LdBPK_340010.1 , LdCL_340005100 , LDHU3_34.0030

Length:

273

Annotations

LeishMANIAdb annotations

These proteins belong to short-chain dehydrogenases / reductases using NAD or NADP as cofactor. All homologs are used for very long fatty acid biosynthesis.. Expanded in multiple organisms, but especially Strigomonas. Localization: ER (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3Q8IE20

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IE20

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0016491	oxidoreductase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	203	205	PF00675	0.454
CLV_NRD_NRD_1	269	271	PF00675	0.428
CLV_NRD_NRD_1	31	33	PF00675	0.303
CLV_PCSK_KEX2_1	137	139	PF00082	0.316
CLV_PCSK_KEX2_1	271	273	PF00082	0.465
CLV_PCSK_KEX2_1	3	5	PF00082	0.397
CLV_PCSK_KEX2_1	31	33	PF00082	0.264
CLV_PCSK_PC1ET2_1	137	139	PF00082	0.354
CLV_PCSK_PC1ET2_1	271	273	PF00082	0.481
CLV_PCSK_PC1ET2_1	3	5	PF00082	0.397
CLV_PCSK_SKI1_1	114	118	PF00082	0.241
CLV_PCSK_SKI1_1	262	266	PF00082	0.402
DEG_Nend_UBRbox_1	1	4	PF02207	0.271
DOC_CKS1_1	230	235	PF01111	0.348
DOC_MAPK_gen_1	135	145	PF00069	0.264
DOC_MAPK_gen_1	204	213	PF00069	0.383
DOC_MAPK_gen_1	31	38	PF00069	0.276
DOC_MAPK_MEF2A_6	84	91	PF00069	0.363
DOC_PP1_RVXF_1	59	66	PF00149	0.264
DOC_USP7_UBL2_3	133	137	PF12436	0.357
DOC_USP7_UBL2_3	267	271	PF12436	0.525
DOC_WW_Pin1_4	149	154	PF00397	0.279
DOC_WW_Pin1_4	186	191	PF00397	0.241
DOC_WW_Pin1_4	229	234	PF00397	0.359
DOC_WW_Pin1_4	68	73	PF00397	0.463
LIG_BRCT_BRCA1_1	63	67	PF00533	0.302
LIG_FHA_1	125	131	PF00498	0.362
LIG_FHA_1	196	202	PF00498	0.295
LIG_FHA_1	248	254	PF00498	0.476
LIG_LIR_Apic_2	127	132	PF02991	0.280
LIG_LIR_Gen_1	10	17	PF02991	0.264
LIG_LIR_Gen_1	101	109	PF02991	0.404
LIG_LIR_Gen_1	208	218	PF02991	0.382
LIG_LIR_Gen_1	76	87	PF02991	0.337
LIG_LIR_Nem_3	10	14	PF02991	0.252
LIG_LIR_Nem_3	101	107	PF02991	0.305
LIG_LIR_Nem_3	208	213	PF02991	0.398
LIG_LIR_Nem_3	76	82	PF02991	0.267
LIG_Pex14_2	166	170	PF04695	0.252
LIG_SH2_GRB2like	100	103	PF00017	0.264
LIG_SH2_PTP2	129	132	PF00017	0.357
LIG_SH2_STAP1	100	104	PF00017	0.264
LIG_SH2_STAP1	23	27	PF00017	0.338
LIG_SH2_STAP1	75	79	PF00017	0.357
LIG_SH2_STAT5	129	132	PF00017	0.357
LIG_SH2_STAT5	252	255	PF00017	0.438
LIG_SH2_STAT5	98	101	PF00017	0.303
LIG_SH3_3	227	233	PF00018	0.570
LIG_SUMO_SIM_anti_2	86	91	PF11976	0.295
LIG_SUMO_SIM_par_1	141	147	PF11976	0.280
LIG_SUMO_SIM_par_1	184	189	PF11976	0.252
LIG_TRAF2_2	72	77	PF00917	0.242
LIG_UBA3_1	78	84	PF00899	0.357
MOD_CDK_SPK_2	68	73	PF00069	0.242
MOD_CDK_SPxxK_3	229	236	PF00069	0.310
MOD_CK1_1	149	155	PF00069	0.305
MOD_CK1_1	195	201	PF00069	0.264
MOD_CK2_1	41	47	PF00069	0.381
MOD_Cter_Amidation	29	32	PF01082	0.389
MOD_GlcNHglycan	148	151	PF01048	0.325
MOD_GlcNHglycan	68	71	PF01048	0.383
MOD_GSK3_1	120	127	PF00069	0.317
MOD_GSK3_1	156	163	PF00069	0.265
MOD_GSK3_1	195	202	PF00069	0.257
MOD_GSK3_1	225	232	PF00069	0.430
MOD_GSK3_1	247	254	PF00069	0.502
MOD_GSK3_1	41	48	PF00069	0.429
MOD_N-GLC_1	166	171	PF02516	0.325
MOD_N-GLC_1	96	101	PF02516	0.294
MOD_N-GLC_2	35	37	PF02516	0.252
MOD_NEK2_1	144	149	PF00069	0.368
MOD_NEK2_1	156	161	PF00069	0.280
MOD_NEK2_1	166	171	PF00069	0.240
MOD_NEK2_1	192	197	PF00069	0.249
MOD_NEK2_2	120	125	PF00069	0.325
MOD_PIKK_1	195	201	PF00454	0.252
MOD_PK_1	225	231	PF00069	0.481
MOD_PK_1	45	51	PF00069	0.373
MOD_PKA_2	124	130	PF00069	0.264
MOD_PKA_2	206	212	PF00069	0.418
MOD_Plk_1	120	126	PF00069	0.373
MOD_Plk_1	166	172	PF00069	0.325
MOD_Plk_1	96	102	PF00069	0.278
MOD_Plk_4	206	212	PF00069	0.425
MOD_Plk_4	45	51	PF00069	0.373
MOD_ProDKin_1	149	155	PF00069	0.279
MOD_ProDKin_1	186	192	PF00069	0.241
MOD_ProDKin_1	229	235	PF00069	0.354
MOD_ProDKin_1	68	74	PF00069	0.463
MOD_SUMO_rev_2	47	56	PF00179	0.332
TRG_DiLeu_BaEn_1	86	91	PF01217	0.289
TRG_DiLeu_BaLyEn_6	111	116	PF01217	0.389
TRG_DiLeu_BaLyEn_6	152	157	PF01217	0.325
TRG_ENDOCYTIC_2	75	78	PF00928	0.241
TRG_NES_CRM1_1	108	121	PF08389	0.357
TRG_Pf-PMV_PEXEL_1	246	251	PF00026	0.374

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0E3D8L9	Penicillium crustosum	29%	100%
A0A0N1HTS4	Leptomonas seymouri	32%	84%
A0A0N1I6F8	Leptomonas seymouri	80%	88%
A0A0N1PCK0	Leptomonas seymouri	27%	100%
A0A0S4IR33	Bodo saltans	54%	80%
A0A0S4IWL0	Bodo saltans	58%	86%
A0A0S4JBE7	Bodo saltans	52%	83%
A0A0S4JCK7	Bodo saltans	29%	100%
A0A0S4JNE8	Bodo saltans	29%	85%
A0A0S4JSF1	Bodo saltans	30%	68%
A0A140FAN3	Pinus massoniana	27%	77%
A0A1A9TAK5	Narcissus pseudonarcissus	25%	100%
A0A1C9II22	Narcissus aff. pseudonarcissus MK-2014	25%	100%
A0A1L9WLH9	Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094)	29%	100%
A0A1X0NWL8	Trypanosomatidae	61%	88%
A0A1X0P0X1	Trypanosomatidae	22%	100%
A0A1X0P1C4	Trypanosomatidae	32%	83%
A0A2I1C3T5	Aspergillus novofumigatus (strain IBT 16806)	28%	100%
A0A2U8U2K8	Sarocladium schorii	24%	100%
A0A3S7X6T1	Leishmania donovani	32%	84%
A0A3S7X793	Leishmania donovani	100%	89%
A0A411PQN6	Paecilomyces divaricatus	28%	100%
A0A422NCL5	Trypanosoma rangeli	23%	100%
A0A422NG64	Trypanosoma rangeli	30%	83%
A0A422NJG3	Trypanosoma rangeli	64%	88%
A0A422NNE9	Trypanosoma rangeli	27%	81%
A0A4P8DJW8	Cryptosporiopsis sp. (strain 8999)	27%	100%
A0A5B8YU81	Pestalotiopsis microspora	29%	100%
A1C6J8	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	33%	79%
A1DH66	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	79%
A2QCH3	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	79%
A3LXZ3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	79%
A4ECA9	Collinsella aerofaciens (strain ATCC 25986 / DSM 3979 / JCM 10188 / KCTC 3647 / NCTC 11838 / VPI 1003)	22%	100%
A4HAC6	Leishmania braziliensis	88%	100%
A4HLM0	Leishmania braziliensis	31%	84%
A4HME4	Leishmania braziliensis	24%	100%
A4I931	Leishmania infantum	32%	84%
A4I9G9	Leishmania infantum	99%	100%
A4IFA7	Bos taurus	27%	100%
A4QTE3	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	31%	82%
A5DND6	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	36%	80%
A5E0R1	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	31%	78%
A5JYX5	Caenorhabditis elegans	24%	88%
A5PJF6	Bos taurus	33%	83%
A5WWC6	Danio rerio	27%	86%
A6NNS2	Homo sapiens	25%	88%
A6RBW9	Ajellomyces capsulatus (strain NAm1 / WU24)	32%	81%
A6SG70	Botryotinia fuckeliana (strain B05.10)	31%	82%
A6ZLA1	Saccharomyces cerevisiae (strain YJM789)	32%	79%
A7B4V1	Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9)	20%	100%
A7DY56	Cochlearia officinalis	26%	100%
A7F8T1	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	31%	82%
A7LB59	Arachis hypogaea	25%	77%
A7TMJ2	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	32%	79%
A8N6B4	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	37%	81%
A8Q1U2	Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)	35%	84%
A9UM79	Xenopus tropicalis	26%	88%
B0D8R3	Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686)	31%	81%
B0XSI3	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	32%	79%
B0ZT44	Elsinoe fawcettii	24%	100%
B2B3L4	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	31%	80%
B2WMJ3	Pyrenophora tritici-repentis (strain Pt-1C-BFP)	32%	80%
B3LN00	Saccharomyces cerevisiae (strain RM11-1a)	32%	79%
B6H060	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	28%	92%
C9ZNQ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	88%
D0A2C4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	78%
D0A4Z5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A534	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	83%
D3U1D9	Klebsiella oxytoca	25%	100%
D3ZGP9	Rattus norvegicus	24%	88%
D4A1J4	Rattus norvegicus	29%	100%
E3VWI6	Streptomyces arenae	26%	97%
E3VWK2	Streptomyces exfoliatus	28%	99%
E9AEU5	Leishmania major	24%	100%
E9B3Z6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	84%
E9B4G7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
F4IKM1	Arabidopsis thaliana	27%	89%
F9XMW6	Zymoseptoria tritici (strain CBS 115943 / IPO323)	24%	100%
G4N286	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	28%	96%
G5EGA6	Caenorhabditis elegans	30%	100%
G9FRD6	Clostridium sardiniense	25%	100%
G9FRD7	Clostridium sardiniense	28%	100%
H9BFQ2	Erythroxylum coca	22%	100%
M2ZIX7	Pseudocercospora fijiensis (strain CIRAD86)	30%	88%
O07399	Mycobacterium avium	24%	100%
O16925	Caenorhabditis elegans	28%	100%
O17795	Caenorhabditis elegans	28%	87%
O31767	Bacillus subtilis (strain 168)	26%	100%
O32229	Bacillus subtilis (strain 168)	28%	100%
O34782	Bacillus subtilis (strain 168)	30%	100%
O34896	Bacillus subtilis (strain 168)	24%	98%
O49332	Arabidopsis thaliana	28%	100%
O54438	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	32%	100%
O54939	Rattus norvegicus	32%	89%
O57314	Anas platyrhynchos	37%	88%
O67610	Aquifex aeolicus (strain VF5)	28%	100%
O70503	Mus musculus	34%	88%
O86034	Rhizobium meliloti (strain 1021)	26%	100%
P00335	Klebsiella aerogenes	25%	100%
P06234	Rhizobium meliloti (strain 1021)	28%	100%
P07772	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	25%	100%
P07914	Clostridium scindens (strain JCM 10418 / VPI 12708)	24%	100%
P0A0H9	Staphylococcus aureus (strain Mu50 / ATCC 700699)	35%	100%
P0A0I0	Staphylococcus aureus (strain MW2)	35%	100%
P0A2C9	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	31%	100%
P0A2D0	Salmonella typhi	31%	100%
P0A2D1	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	29%	100%
P0A2D2	Salmonella typhi	29%	100%
P0A9P9	Escherichia coli (strain K12)	26%	100%
P0A9Q0	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
P0AEK2	Escherichia coli (strain K12)	31%	100%
P0AEK3	Shigella flexneri	31%	100%
P0AFP4	Escherichia coli (strain K12)	26%	100%
P0AFP5	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
P0CG22	Homo sapiens	25%	97%
P0CR34	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	30%	76%
P0CR35	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	30%	76%
P0DKC5	Arabidopsis thaliana	28%	78%
P0DKC6	Arabidopsis thaliana	28%	78%
P0DKC7	Arabidopsis thaliana	26%	91%
P0DKI3	Arabidopsis thaliana	24%	100%
P16544	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	29%	100%
P17611	Azospirillum brasilense	29%	100%
P19337	Clostridium scindens (strain JCM 10418 / VPI 12708)	26%	100%
P25970	Myxococcus xanthus (strain DK1622)	28%	100%
P33207	Arabidopsis thaliana	31%	86%
P37058	Homo sapiens	31%	88%
P37440	Escherichia coli (strain K12)	28%	100%
P37694	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	25%	95%
P37959	Bacillus subtilis (strain 168)	27%	98%
P38004	Chlamydia trachomatis (strain D/UW-3/Cx)	25%	100%
P38286	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	79%
P39071	Bacillus subtilis (strain 168)	29%	100%
P39577	Bacillus subtilis (strain 168)	25%	100%
P39831	Escherichia coli (strain K12)	25%	100%
P40397	Bacillus subtilis (strain 168)	25%	96%
P40471	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	92%
P41177	Streptomyces virginiae	31%	100%
P43713	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	29%	100%
P45200	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	28%	100%
P50162	Datura stramonium	24%	100%
P50163	Datura stramonium	25%	100%
P50164	Hyoscyamus niger	23%	100%
P50165	Datura stramonium	25%	100%
P50199	Gluconobacter oxydans (strain 621H)	24%	100%
P50200	Paeniclostridium sordellii	26%	100%
P50204	Paracoccus denitrificans	26%	100%
P50941	Rickettsia prowazekii (strain Madrid E)	25%	100%
P51658	Mus musculus	24%	72%
P51831	Bacillus subtilis (strain 168)	31%	100%
P52037	Escherichia coli (strain K12)	30%	100%
P55336	Vibrio harveyi	29%	100%
P55434	Sinorhizobium fredii (strain NBRC 101917 / NGR234)	29%	100%
P57432	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	26%	100%
P69935	Salmonella typhi	27%	100%
P69936	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
P70385	Mus musculus	31%	90%
P70720	Aggregatibacter actinomycetemcomitans	26%	100%
P72332	Rhizobium sp. (strain N33)	30%	100%
P73574	Synechocystis sp. (strain PCC 6803 / Kazusa)	32%	100%
P87025	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	25%	97%
P99093	Staphylococcus aureus (strain N315)	35%	100%
P9WGR6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	24%	100%
P9WGR7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	24%	100%
Q01198	Sphingobium sp. (strain NBRC 103272 / SYK-6)	25%	90%
Q05016	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
Q06136	Homo sapiens	21%	82%
Q09517	Caenorhabditis elegans	33%	86%
Q09851	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	92%
Q0CY11	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	33%	77%
Q0IH28	Xenopus laevis	22%	85%
Q0U3N7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	80%
Q0VFE7	Xenopus tropicalis	22%	88%
Q10130	Caenorhabditis elegans	30%	72%
Q10245	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	80%
Q12634	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	26%	96%
Q13268	Homo sapiens	27%	98%
Q15SS0	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	23%	100%
Q17703	Caenorhabditis elegans	28%	87%
Q17704	Caenorhabditis elegans	26%	87%
Q1DNC5	Coccidioides immitis (strain RS)	32%	78%
Q28IU1	Xenopus tropicalis	38%	85%
Q2FE21	Staphylococcus aureus (strain USA300)	28%	100%
Q2FVD5	Staphylococcus aureus (strain NCTC 8325 / PS 47)	28%	100%
Q2H1V7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	32%	80%
Q2KIJ5	Bos taurus	21%	82%
Q2UET3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	79%
Q3SXM5	Homo sapiens	32%	83%
Q3T046	Bos taurus	28%	100%
Q3T0R4	Bos taurus	23%	84%
Q3U0B3	Mus musculus	26%	100%
Q42182	Arabidopsis thaliana	29%	100%
Q45219	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	26%	97%
Q49117	Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)	33%	100%
Q49WS9	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	28%	100%
Q4A054	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	29%	100%
Q4JK73	Macaca fascicularis	25%	91%
Q4L8Y1	Staphylococcus haemolyticus (strain JCSC1435)	27%	100%
Q4P622	Ustilago maydis (strain 521 / FGSC 9021)	36%	78%
Q4Q3K8	Leishmania major	94%	100%
Q4Q428	Leishmania major	32%	84%
Q4R5G7	Macaca fascicularis	35%	88%
Q4V8B7	Rattus norvegicus	30%	83%
Q4X117	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	79%
Q53GQ0	Homo sapiens	33%	88%
Q566S6	Danio rerio	26%	88%
Q59787	Cereibacter sphaeroides	28%	100%
Q59V93	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	78%
Q5B0R9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	79%
Q5BH34	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	28%	100%
Q5E9H7	Bos taurus	33%	88%
Q5HD73	Staphylococcus aureus (strain COL)	28%	100%
Q5HGK2	Staphylococcus aureus (strain COL)	35%	100%
Q5HLD8	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	30%	100%
Q5HPW0	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	34%	100%
Q5LA59	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	22%	100%
Q5NVG2	Pongo abelii	24%	91%
Q5P5I4	Aromatoleum aromaticum (strain EbN1)	31%	100%
Q5R6U1	Pongo abelii	24%	84%
Q5R7K0	Pongo abelii	33%	83%
Q5RCF8	Pongo abelii	27%	98%
Q5RJY4	Rattus norvegicus	25%	84%
Q5XG41	Xenopus laevis	36%	86%
Q5ZJG8	Gallus gallus	35%	82%
Q60V51	Caenorhabditis briggsae	32%	86%
Q62730	Rattus norvegicus	26%	72%
Q68VY7	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	26%	100%
Q6AYS8	Rattus norvegicus	24%	92%
Q6BIG0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	79%
Q6CHP1	Yarrowia lipolytica (strain CLIB 122 / E 150)	33%	70%
Q6CVS4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	79%
Q6F7B8	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	26%	93%
Q6FRM0	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	78%
Q6G6J1	Staphylococcus aureus (strain MSSA476)	28%	100%
Q6G9Y2	Staphylococcus aureus (strain MSSA476)	35%	100%
Q6GDV6	Staphylococcus aureus (strain MRSA252)	29%	100%
Q6GHK4	Staphylococcus aureus (strain MRSA252)	35%	100%
Q6GV12	Mus musculus	21%	82%
Q6IAN0	Homo sapiens	23%	84%
Q6P0H7	Danio rerio	28%	100%
Q6P3L6	Danio rerio	37%	86%
Q6P7R8	Rattus norvegicus	35%	88%
Q6QA32	Danio rerio	32%	89%
Q6QA33	Danio rerio	34%	88%
Q6TMA3	Rhodococcus sp. (strain TK6)	24%	100%
Q6UWP2	Homo sapiens	27%	100%
Q71R50	Gallus gallus	25%	100%
Q75A60	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	78%
Q7A3L9	Staphylococcus aureus (strain N315)	28%	100%
Q7Q732	Anopheles gambiae	27%	86%
Q7RYE5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	82%
Q7SHI2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	94%
Q7TQA3	Mus musculus	23%	88%
Q7Z5P4	Homo sapiens	24%	91%
Q82IY9	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	26%	100%
Q83RE8	Shigella flexneri	25%	100%
Q84ST4	Oryza sativa subsp. japonica	28%	80%
Q89AG9	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	27%	100%
Q8AVY8	Xenopus laevis	37%	86%
Q8BTX9	Mus musculus	30%	83%
Q8CHS7	Mus musculus	24%	88%
Q8CN40	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	30%	100%
Q8CPI3	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	34%	100%
Q8CQD2	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	26%	100%
Q8FHD2	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	25%	100%
Q8GAV9	Comamonas sp. (strain NCIMB 9872)	26%	100%
Q8JZV9	Mus musculus	29%	100%
Q8K9J5	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	27%	100%
Q8L9C4	Arabidopsis thaliana	31%	86%
Q8LEU3	Arabidopsis thaliana	24%	78%
Q8LKV5	Sesamum indicum	26%	75%
Q8N4T8	Homo sapiens	28%	100%
Q8NBQ5	Homo sapiens	24%	91%
Q8NUV9	Staphylococcus aureus (strain MW2)	28%	100%
Q8SPU8	Bos taurus	27%	98%
Q8U8I2	Agrobacterium fabrum (strain C58 / ATCC 33970)	30%	100%
Q8WNV7	Sus scrofa	29%	98%
Q8X505	Escherichia coli O157:H7	25%	100%
Q8XBJ4	Escherichia coli O157:H7	28%	100%
Q937L4	Comamonas testosteroni	26%	100%
Q93W57	Sesamum indicum	30%	78%
Q93X62	Brassica napus	32%	85%
Q93X67	Brassica napus	32%	83%
Q93X68	Brassica napus	33%	86%
Q949M2	Brassica napus	34%	100%
Q949M3	Brassica napus	32%	87%
Q988B7	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	28%	100%
Q99J47	Mus musculus	25%	85%
Q99LB2	Mus musculus	28%	98%
Q99RF5	Staphylococcus aureus (strain Mu50 / ATCC 700699)	28%	100%
Q9BTZ2	Homo sapiens	27%	98%
Q9CXR1	Mus musculus	28%	81%
Q9EQ06	Mus musculus	25%	92%
Q9FYL6	Arabidopsis thaliana	39%	88%
Q9GKX2	Oryctolagus cuniculus	25%	100%
Q9HK58	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	27%	100%
Q9KQH7	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	29%	100%
Q9KWN1	Rhizobium radiobacter	29%	100%
Q9L9F8	Streptomyces niveus	31%	100%
Q9LUF2	Arabidopsis thaliana	26%	91%
Q9N126	Bos taurus	27%	88%
Q9NYR8	Homo sapiens	28%	88%
Q9P7B4	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
Q9PKF7	Chlamydia muridarum (strain MoPn / Nigg)	27%	100%
Q9SQR4	Arabidopsis thaliana	25%	100%
Q9STY7	Arabidopsis thaliana	30%	88%
Q9STY8	Arabidopsis thaliana	25%	89%
Q9WYG0	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	28%	100%
Q9X248	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	30%	100%
Q9X6U2	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	24%	100%
Q9Y140	Drosophila melanogaster	25%	84%
Q9Y394	Homo sapiens	27%	81%
Q9ZW03	Arabidopsis thaliana	26%	100%
Q9ZW04	Arabidopsis thaliana	25%	100%
Q9ZW12	Arabidopsis thaliana	24%	85%
Q9ZW13	Arabidopsis thaliana	24%	100%
Q9ZW14	Arabidopsis thaliana	28%	100%
Q9ZW15	Arabidopsis thaliana	28%	100%
Q9ZW16	Arabidopsis thaliana	27%	100%
Q9ZW19	Arabidopsis thaliana	25%	100%
Q9ZW20	Arabidopsis thaliana	24%	100%
R9UAM1	Ruminococcus gnavus	20%	100%
T2KLZ8	Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)	25%	100%
V5B6S6	Trypanosoma cruzi	61%	88%
V5BCN8	Trypanosoma cruzi	27%	83%