LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8IE04_LEIDO
TriTrypDb:
LdCL_260031000 , LDHU3_26.3240
Length:
231

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IE04
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IE04

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 34 36 PF00675 0.408
CLV_PCSK_SKI1_1 127 131 PF00082 0.469
CLV_PCSK_SKI1_1 155 159 PF00082 0.468
CLV_PCSK_SKI1_1 35 39 PF00082 0.394
CLV_PCSK_SKI1_1 64 68 PF00082 0.363
CLV_Separin_Metazoa 57 61 PF03568 0.419
DOC_MAPK_gen_1 35 43 PF00069 0.393
DOC_MAPK_gen_1 60 67 PF00069 0.375
DOC_MAPK_MEF2A_6 96 103 PF00069 0.338
DOC_MAPK_NFAT4_5 96 104 PF00069 0.343
DOC_USP7_MATH_1 186 190 PF00917 0.419
DOC_USP7_MATH_1 197 201 PF00917 0.412
DOC_USP7_MATH_1 217 221 PF00917 0.450
DOC_USP7_MATH_1 5 9 PF00917 0.465
DOC_WW_Pin1_4 224 229 PF00397 0.473
LIG_14-3-3_CanoR_1 161 167 PF00244 0.449
LIG_APCC_ABBA_1 219 224 PF00400 0.463
LIG_BIR_III_4 21 25 PF00653 0.422
LIG_BRCT_BRCA1_1 188 192 PF00533 0.407
LIG_BRCT_BRCA1_1 199 203 PF00533 0.406
LIG_FHA_1 178 184 PF00498 0.441
LIG_FHA_1 38 44 PF00498 0.394
LIG_FHA_2 16 22 PF00498 0.437
LIG_LIR_Nem_3 84 90 PF02991 0.336
LIG_PTB_Apo_2 66 73 PF02174 0.353
LIG_SH2_CRK 170 174 PF00017 0.420
LIG_SH2_CRK 90 94 PF00017 0.372
LIG_SH2_STAP1 170 174 PF00017 0.420
LIG_SH2_STAP1 90 94 PF00017 0.372
LIG_SH2_STAT3 79 82 PF00017 0.385
LIG_SH2_STAT5 87 90 PF00017 0.334
LIG_SH2_STAT5 98 101 PF00017 0.329
LIG_SUMO_SIM_par_1 179 185 PF11976 0.440
LIG_SUMO_SIM_par_1 39 46 PF11976 0.401
LIG_TRAF2_1 204 207 PF00917 0.414
LIG_TYR_ITIM 88 93 PF00017 0.354
MOD_CDK_SPxxK_3 224 231 PF00069 0.478
MOD_CK1_1 116 122 PF00069 0.482
MOD_CK2_1 145 151 PF00069 0.454
MOD_CK2_1 201 207 PF00069 0.406
MOD_Cter_Amidation 33 36 PF01082 0.417
MOD_GlcNHglycan 118 121 PF01048 0.492
MOD_GlcNHglycan 184 187 PF01048 0.435
MOD_GlcNHglycan 8 11 PF01048 0.467
MOD_GSK3_1 182 189 PF00069 0.430
MOD_GSK3_1 197 204 PF00069 0.406
MOD_GSK3_1 37 44 PF00069 0.397
MOD_N-GLC_1 6 11 PF02516 0.468
MOD_NEK2_1 41 46 PF00069 0.411
MOD_NEK2_2 217 222 PF00069 0.454
MOD_NEK2_2 23 28 PF00069 0.400
MOD_PIKK_1 43 49 PF00454 0.417
MOD_PK_1 81 87 PF00069 0.353
MOD_Plk_1 127 133 PF00069 0.456
MOD_Plk_1 138 144 PF00069 0.470
MOD_Plk_4 162 168 PF00069 0.440
MOD_Plk_4 177 183 PF00069 0.437
MOD_Plk_4 217 223 PF00069 0.455
MOD_ProDKin_1 224 230 PF00069 0.474
TRG_ENDOCYTIC_2 170 173 PF00928 0.421
TRG_ENDOCYTIC_2 90 93 PF00928 0.367
TRG_ENDOCYTIC_2 98 101 PF00928 0.329
TRG_Pf-PMV_PEXEL_1 28 32 PF00026 0.399

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS