Right handed beta helix region family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Right handed beta helix region, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IDZ0_LEIDO

TriTrypDb:

LdBPK_292820.1 , LdCL_290034300 , LDHU3_29.4140

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8IDZ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDZ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	61	65	PF00656	0.475
CLV_NRD_NRD_1	184	186	PF00675	0.352
CLV_NRD_NRD_1	199	201	PF00675	0.327
CLV_NRD_NRD_1	93	95	PF00675	0.302
CLV_PCSK_SKI1_1	88	92	PF00082	0.240
DOC_MAPK_gen_1	200	206	PF00069	0.335
DOC_USP7_MATH_1	270	274	PF00917	0.521
DOC_USP7_MATH_1	57	61	PF00917	0.629
LIG_APCC_ABBA_1	179	184	PF00400	0.433
LIG_FHA_1	117	123	PF00498	0.433
LIG_FHA_1	176	182	PF00498	0.453
LIG_FHA_1	262	268	PF00498	0.504
LIG_FHA_1	3	9	PF00498	0.424
LIG_FHA_1	40	46	PF00498	0.430
LIG_FHA_1	71	77	PF00498	0.360
LIG_FHA_2	146	152	PF00498	0.404
LIG_LIR_Nem_3	143	147	PF02991	0.438
LIG_LIR_Nem_3	176	182	PF02991	0.297
LIG_LIR_Nem_3	218	224	PF02991	0.531
LIG_LRP6_Inhibitor_1	169	175	PF00058	0.309
LIG_REV1ctd_RIR_1	225	235	PF16727	0.442
LIG_SH2_STAP1	183	187	PF00017	0.433
LIG_SH2_STAT5	138	141	PF00017	0.313
LIG_SH2_STAT5	205	208	PF00017	0.313
LIG_SH3_3	4	10	PF00018	0.544
LIG_SH3_3	40	46	PF00018	0.512
LIG_SUMO_SIM_par_1	72	77	PF11976	0.461
MOD_CK1_1	238	244	PF00069	0.458
MOD_CK1_1	60	66	PF00069	0.676
MOD_CK2_1	140	146	PF00069	0.333
MOD_GlcNHglycan	187	190	PF01048	0.418
MOD_GlcNHglycan	237	240	PF01048	0.455
MOD_GlcNHglycan	261	264	PF01048	0.455
MOD_GlcNHglycan	76	79	PF01048	0.442
MOD_GSK3_1	238	245	PF00069	0.418
MOD_GSK3_1	66	73	PF00069	0.526
MOD_GSK3_1	74	81	PF00069	0.357
MOD_N-GLC_1	47	52	PF02516	0.492
MOD_N-GLC_1	78	83	PF02516	0.391
MOD_NEK2_1	140	145	PF00069	0.415
MOD_NEK2_1	227	232	PF00069	0.416
MOD_NEK2_1	242	247	PF00069	0.260
MOD_NEK2_1	39	44	PF00069	0.508
MOD_NEK2_1	47	52	PF00069	0.479
MOD_NEK2_2	118	123	PF00069	0.333
MOD_NEK2_2	270	275	PF00069	0.526
MOD_PIKK_1	145	151	PF00454	0.351
MOD_PKA_1	185	191	PF00069	0.351
MOD_PKA_2	233	239	PF00069	0.365
MOD_PKB_1	173	181	PF00069	0.418
MOD_Plk_1	175	181	PF00069	0.396
MOD_Plk_1	215	221	PF00069	0.351
MOD_Plk_1	39	45	PF00069	0.403
MOD_Plk_1	47	53	PF00069	0.356
MOD_Plk_1	78	84	PF00069	0.340
MOD_Plk_2-3	192	198	PF00069	0.313
MOD_Plk_4	2	8	PF00069	0.544
MOD_Plk_4	28	34	PF00069	0.454
MOD_Plk_4	66	72	PF00069	0.510
TRG_DiLeu_BaEn_4	40	46	PF01217	0.484

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL58	Leptomonas seymouri	54%	99%
A0A0S4KFM6	Bodo saltans	38%	100%
A0A1X0P907	Trypanosomatidae	48%	100%
A0A422NEU4	Trypanosoma rangeli	47%	100%
A4HHS8	Leishmania braziliensis	81%	100%
A4I4X9	Leishmania infantum	100%	100%
C9ZKL1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
E9AED3	Leishmania major	96%	100%
E9ALF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5C239	Trypanosoma cruzi	49%	100%