Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IDV0_LEIDO

TriTrypDb:

LdBPK_332050.1 , LdCL_330027400 , LDHU3_33.2970

Length:

650

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	17
GO:0110165	cellular anatomical entity	1	17

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Expansion

Sequence features

A0A3Q8IDV0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDV0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	105	109	PF00656	0.731
CLV_C14_Caspase3-7	197	201	PF00656	0.707
CLV_C14_Caspase3-7	454	458	PF00656	0.450
CLV_C14_Caspase3-7	635	639	PF00656	0.567
CLV_C14_Caspase3-7	91	95	PF00656	0.606
CLV_NRD_NRD_1	13	15	PF00675	0.543
CLV_NRD_NRD_1	30	32	PF00675	0.454
CLV_NRD_NRD_1	339	341	PF00675	0.477
CLV_NRD_NRD_1	626	628	PF00675	0.502
CLV_PCSK_FUR_1	375	379	PF00082	0.388

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IIV3	Bodo saltans	24%	85%
A0A0S4IZJ9	Bodo saltans	27%	68%
A0A1X0NUP0	Trypanosomatidae	20%	100%
A0A1X0P3P0	Trypanosomatidae	36%	95%
A0A3R7R847	Trypanosoma rangeli	31%	98%
A0A3S7X5M8	Leishmania donovani	22%	100%
A0A422MY34	Trypanosoma rangeli	23%	100%
A4HKK2	Leishmania braziliensis	22%	100%
A4HLQ6	Leishmania braziliensis	77%	100%
A4I834	Leishmania infantum	22%	100%

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