Separase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Separase

Gene product:

Peptidase C50 separase, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IDS1_LEIDO

TriTrypDb:

LdBPK_201650.1 , LdCL_200021300 , LDHU3_20.2020

Length:

1279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7
GO:0005737	cytoplasm	2	1
GO:0005813	centrosome	3	1
GO:0005815	microtubule organizing center	2	1
GO:0005819	spindle	5	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0072686	mitotic spindle	6	1

Expansion

Sequence features

A0A3Q8IDS1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDS1

Function

Biological processes
Term	Name	Level	Count
GO:0000280	nuclear division	6	6
GO:0006508	proteolysis	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006996	organelle organization	4	6
GO:0007059	chromosome segregation	2	6
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	6
GO:0019538	protein metabolic process	3	7
GO:0022402	cell cycle process	2	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044238	primary metabolic process	2	7
GO:0048285	organelle fission	5	6
GO:0071704	organic substance metabolic process	2	7
GO:0071840	cellular component organization or biogenesis	2	6
GO:0098813	nuclear chromosome segregation	3	6
GO:1901564	organonitrogen compound metabolic process	3	7
GO:0022414	reproductive process	1	1
GO:0051304	chromosome separation	3	1
GO:0051307	meiotic chromosome separation	3	1
GO:1903046	meiotic cell cycle process	2	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0004175	endopeptidase activity	4	7
GO:0004197	cysteine-type endopeptidase activity	5	7
GO:0008233	peptidase activity	3	7
GO:0008234	cysteine-type peptidase activity	4	7
GO:0016787	hydrolase activity	2	7
GO:0140096	catalytic activity, acting on a protein	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1208	1212	PF00656	0.473
CLV_C14_Caspase3-7	1228	1232	PF00656	0.377
CLV_C14_Caspase3-7	609	613	PF00656	0.474
CLV_C14_Caspase3-7	614	618	PF00656	0.500
CLV_C14_Caspase3-7	619	623	PF00656	0.543
CLV_C14_Caspase3-7	822	826	PF00656	0.467
CLV_NRD_NRD_1	1004	1006	PF00675	0.505
CLV_NRD_NRD_1	1121	1123	PF00675	0.258
CLV_NRD_NRD_1	1245	1247	PF00675	0.442
CLV_NRD_NRD_1	182	184	PF00675	0.492
CLV_NRD_NRD_1	205	207	PF00675	0.525
CLV_NRD_NRD_1	218	220	PF00675	0.309
CLV_NRD_NRD_1	340	342	PF00675	0.466
CLV_NRD_NRD_1	375	377	PF00675	0.354
CLV_NRD_NRD_1	433	435	PF00675	0.455
CLV_NRD_NRD_1	641	643	PF00675	0.479
CLV_NRD_NRD_1	652	654	PF00675	0.500
CLV_NRD_NRD_1	698	700	PF00675	0.412
CLV_NRD_NRD_1	800	802	PF00675	0.446
CLV_PCSK_FUR_1	338	342	PF00082	0.511
CLV_PCSK_FUR_1	797	801	PF00082	0.497
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.505
CLV_PCSK_KEX2_1	1121	1123	PF00082	0.258
CLV_PCSK_KEX2_1	1245	1247	PF00082	0.442
CLV_PCSK_KEX2_1	182	184	PF00082	0.492
CLV_PCSK_KEX2_1	205	207	PF00082	0.526
CLV_PCSK_KEX2_1	218	220	PF00082	0.307
CLV_PCSK_KEX2_1	340	342	PF00082	0.466
CLV_PCSK_KEX2_1	375	377	PF00082	0.354
CLV_PCSK_KEX2_1	433	435	PF00082	0.455
CLV_PCSK_KEX2_1	652	654	PF00082	0.517
CLV_PCSK_KEX2_1	698	700	PF00082	0.412
CLV_PCSK_KEX2_1	799	801	PF00082	0.625
CLV_PCSK_KEX2_1	917	919	PF00082	0.466
CLV_PCSK_PC1ET2_1	917	919	PF00082	0.466
CLV_PCSK_SKI1_1	1121	1125	PF00082	0.291
CLV_PCSK_SKI1_1	1151	1155	PF00082	0.324
CLV_PCSK_SKI1_1	205	209	PF00082	0.506
CLV_PCSK_SKI1_1	218	222	PF00082	0.328
CLV_PCSK_SKI1_1	341	345	PF00082	0.564
CLV_PCSK_SKI1_1	572	576	PF00082	0.451
CLV_PCSK_SKI1_1	605	609	PF00082	0.410
CLV_PCSK_SKI1_1	921	925	PF00082	0.470
CLV_PCSK_SKI1_1	987	991	PF00082	0.401
CLV_Separin_Metazoa	331	335	PF03568	0.466
DEG_APCC_DBOX_1	920	928	PF00400	0.450
DEG_COP1_1	1040	1049	PF00400	0.458
DEG_MDM2_SWIB_1	288	296	PF02201	0.462
DEG_SCF_FBW7_1	442	447	PF00400	0.522
DEG_SPOP_SBC_1	576	580	PF00917	0.487
DEG_SPOP_SBC_1	773	777	PF00917	0.565
DOC_ANK_TNKS_1	100	107	PF00023	0.473
DOC_CDC14_PxL_1	880	888	PF14671	0.478
DOC_CKS1_1	664	669	PF01111	0.715
DOC_CYCLIN_RxL_1	1118	1128	PF00134	0.491
DOC_CYCLIN_RxL_1	216	225	PF00134	0.419
DOC_CYCLIN_RxL_1	917	928	PF00134	0.454
DOC_CYCLIN_yCln2_LP_2	514	520	PF00134	0.309
DOC_MAPK_gen_1	917	924	PF00069	0.415
DOC_MAPK_MEF2A_6	1016	1023	PF00069	0.524
DOC_MAPK_MEF2A_6	394	403	PF00069	0.387
DOC_MAPK_MEF2A_6	90	99	PF00069	0.469
DOC_PP1_RVXF_1	623	630	PF00149	0.610
DOC_PP2B_LxvP_1	97	100	PF13499	0.537
DOC_PP2B_PxIxI_1	398	404	PF00149	0.425
DOC_PP4_FxxP_1	1188	1191	PF00568	0.524
DOC_PP4_FxxP_1	321	324	PF00568	0.397
DOC_PP4_FxxP_1	648	651	PF00568	0.374
DOC_SPAK_OSR1_1	544	548	PF12202	0.419
DOC_USP7_MATH_1	1197	1201	PF00917	0.473
DOC_USP7_MATH_1	138	142	PF00917	0.630
DOC_USP7_MATH_1	144	148	PF00917	0.405
DOC_USP7_MATH_1	251	255	PF00917	0.598
DOC_USP7_MATH_1	257	261	PF00917	0.483
DOC_USP7_MATH_1	343	347	PF00917	0.718
DOC_USP7_MATH_1	388	392	PF00917	0.339
DOC_USP7_MATH_1	43	47	PF00917	0.425
DOC_USP7_MATH_1	444	448	PF00917	0.640
DOC_USP7_MATH_1	451	455	PF00917	0.453
DOC_USP7_MATH_1	621	625	PF00917	0.639
DOC_USP7_MATH_1	684	688	PF00917	0.527
DOC_USP7_MATH_1	71	75	PF00917	0.537
DOC_USP7_MATH_1	730	734	PF00917	0.416
DOC_USP7_MATH_1	774	778	PF00917	0.660
DOC_USP7_MATH_1	838	842	PF00917	0.541
DOC_USP7_MATH_1	941	945	PF00917	0.544
DOC_USP7_MATH_1	949	953	PF00917	0.516
DOC_USP7_MATH_1	966	970	PF00917	0.298
DOC_WW_Pin1_4	106	111	PF00397	0.643
DOC_WW_Pin1_4	1114	1119	PF00397	0.473
DOC_WW_Pin1_4	1161	1166	PF00397	0.491
DOC_WW_Pin1_4	245	250	PF00397	0.510
DOC_WW_Pin1_4	309	314	PF00397	0.580
DOC_WW_Pin1_4	362	367	PF00397	0.362
DOC_WW_Pin1_4	440	445	PF00397	0.494
DOC_WW_Pin1_4	447	452	PF00397	0.518
DOC_WW_Pin1_4	663	668	PF00397	0.731
DOC_WW_Pin1_4	74	79	PF00397	0.491
DOC_WW_Pin1_4	888	893	PF00397	0.606
DOC_WW_Pin1_4	987	992	PF00397	0.475
LIG_14-3-3_CanoR_1	1178	1188	PF00244	0.595
LIG_14-3-3_CanoR_1	182	189	PF00244	0.396
LIG_14-3-3_CanoR_1	42	51	PF00244	0.412
LIG_14-3-3_CanoR_1	544	550	PF00244	0.418
LIG_14-3-3_CanoR_1	572	577	PF00244	0.451
LIG_14-3-3_CanoR_1	603	611	PF00244	0.373
LIG_14-3-3_CanoR_1	631	639	PF00244	0.543
LIG_14-3-3_CanoR_1	65	72	PF00244	0.596
LIG_14-3-3_CanoR_1	658	667	PF00244	0.651
LIG_14-3-3_CanoR_1	698	707	PF00244	0.448
LIG_14-3-3_CanoR_1	818	824	PF00244	0.464
LIG_14-3-3_CanoR_1	861	869	PF00244	0.520
LIG_14-3-3_CanoR_1	894	903	PF00244	0.571
LIG_14-3-3_CanoR_1	904	913	PF00244	0.488
LIG_Actin_WH2_2	5	23	PF00022	0.447
LIG_AP2alpha_2	516	518	PF02296	0.299
LIG_APCC_ABBA_1	1067	1072	PF00400	0.458
LIG_APCC_ABBAyCdc20_2	1066	1072	PF00400	0.473
LIG_BIR_III_4	617	621	PF00653	0.526
LIG_BIR_III_4	825	829	PF00653	0.465
LIG_BRCT_BRCA1_1	311	315	PF00533	0.458
LIG_deltaCOP1_diTrp_1	803	810	PF00928	0.485
LIG_DLG_GKlike_1	1045	1052	PF00625	0.458
LIG_FHA_1	1082	1088	PF00498	0.466
LIG_FHA_1	1114	1120	PF00498	0.491
LIG_FHA_1	1165	1171	PF00498	0.491
LIG_FHA_1	15	21	PF00498	0.443
LIG_FHA_1	151	157	PF00498	0.448
LIG_FHA_1	222	228	PF00498	0.462
LIG_FHA_1	314	320	PF00498	0.380
LIG_FHA_1	363	369	PF00498	0.268
LIG_FHA_1	509	515	PF00498	0.387
LIG_FHA_1	526	532	PF00498	0.348
LIG_FHA_1	577	583	PF00498	0.511
LIG_FHA_1	632	638	PF00498	0.540
LIG_FHA_1	674	680	PF00498	0.530
LIG_FHA_1	874	880	PF00498	0.351
LIG_FHA_1	94	100	PF00498	0.446
LIG_FHA_2	1208	1214	PF00498	0.473
LIG_FHA_2	1226	1232	PF00498	0.483
LIG_FHA_2	1234	1240	PF00498	0.351
LIG_FHA_2	232	238	PF00498	0.458
LIG_FHA_2	478	484	PF00498	0.435
LIG_FHA_2	485	491	PF00498	0.392
LIG_FHA_2	604	610	PF00498	0.428
LIG_FHA_2	9	15	PF00498	0.462
LIG_GBD_Chelix_1	401	409	PF00786	0.359
LIG_GBD_Chelix_1	569	577	PF00786	0.440
LIG_HCF-1_HBM_1	1017	1020	PF13415	0.473
LIG_LIR_Apic_2	1186	1191	PF02991	0.524
LIG_LIR_Apic_2	46	51	PF02991	0.402
LIG_LIR_Apic_2	586	590	PF02991	0.580
LIG_LIR_Apic_2	897	903	PF02991	0.480
LIG_LIR_Gen_1	1017	1027	PF02991	0.473
LIG_LIR_Gen_1	1182	1193	PF02991	0.524
LIG_LIR_Gen_1	1218	1225	PF02991	0.443
LIG_LIR_Gen_1	263	273	PF02991	0.384
LIG_LIR_Gen_1	312	322	PF02991	0.494
LIG_LIR_Gen_1	958	966	PF02991	0.366
LIG_LIR_Nem_3	1017	1023	PF02991	0.473
LIG_LIR_Nem_3	1048	1054	PF02991	0.483
LIG_LIR_Nem_3	1182	1188	PF02991	0.524
LIG_LIR_Nem_3	1218	1224	PF02991	0.444
LIG_LIR_Nem_3	1258	1263	PF02991	0.397
LIG_LIR_Nem_3	178	184	PF02991	0.418
LIG_LIR_Nem_3	187	192	PF02991	0.378
LIG_LIR_Nem_3	263	269	PF02991	0.392
LIG_LIR_Nem_3	312	318	PF02991	0.517
LIG_LIR_Nem_3	38	44	PF02991	0.535
LIG_LIR_Nem_3	391	396	PF02991	0.354
LIG_LIR_Nem_3	404	410	PF02991	0.422
LIG_LIR_Nem_3	516	521	PF02991	0.432
LIG_LIR_Nem_3	958	964	PF02991	0.394
LIG_MYND_1	309	313	PF01753	0.492
LIG_MYND_3	1046	1050	PF01753	0.491
LIG_NRBOX	1063	1069	PF00104	0.433
LIG_NRBOX	562	568	PF00104	0.348
LIG_PCNA_yPIPBox_3	259	272	PF02747	0.430
LIG_PCNA_yPIPBox_3	968	978	PF02747	0.460
LIG_Pex14_1	1093	1097	PF04695	0.473
LIG_Pex14_1	806	810	PF04695	0.401
LIG_Pex14_2	1188	1192	PF04695	0.508
LIG_Pex14_2	288	292	PF04695	0.460
LIG_Pex14_2	518	522	PF04695	0.348
LIG_PTB_Apo_2	980	987	PF02174	0.417
LIG_PTB_Phospho_1	980	986	PF10480	0.409
LIG_SH2_CRK	41	45	PF00017	0.540
LIG_SH2_NCK_1	587	591	PF00017	0.511
LIG_SH2_PTP2	396	399	PF00017	0.347
LIG_SH2_PTP2	546	549	PF00017	0.412
LIG_SH2_SRC	1137	1140	PF00017	0.450
LIG_SH2_SRC	682	685	PF00017	0.489
LIG_SH2_STAT5	1020	1023	PF00017	0.473
LIG_SH2_STAT5	1051	1054	PF00017	0.473
LIG_SH2_STAT5	1137	1140	PF00017	0.450
LIG_SH2_STAT5	1194	1197	PF00017	0.473
LIG_SH2_STAT5	1252	1255	PF00017	0.402
LIG_SH2_STAT5	1266	1269	PF00017	0.327
LIG_SH2_STAT5	396	399	PF00017	0.347
LIG_SH2_STAT5	467	470	PF00017	0.387
LIG_SH2_STAT5	546	549	PF00017	0.431
LIG_SH2_STAT5	682	685	PF00017	0.420
LIG_SH2_STAT5	885	888	PF00017	0.445
LIG_SH3_1	552	558	PF00018	0.406
LIG_SH3_3	1112	1118	PF00018	0.499
LIG_SH3_3	236	242	PF00018	0.439
LIG_SH3_3	380	386	PF00018	0.486
LIG_SH3_3	514	520	PF00018	0.321
LIG_SH3_3	552	558	PF00018	0.406
LIG_SH3_3	624	630	PF00018	0.608
LIG_SH3_3	664	670	PF00018	0.591
LIG_SH3_3	92	98	PF00018	0.432
LIG_SUMO_SIM_anti_2	1010	1015	PF11976	0.491
LIG_SUMO_SIM_anti_2	111	118	PF11976	0.494
LIG_SUMO_SIM_anti_2	1167	1173	PF11976	0.458
LIG_SUMO_SIM_anti_2	231	238	PF11976	0.414
LIG_SUMO_SIM_anti_2	477	487	PF11976	0.438
LIG_SUMO_SIM_anti_2	676	681	PF11976	0.383
LIG_SUMO_SIM_par_1	1010	1015	PF11976	0.483
LIG_SUMO_SIM_par_1	115	123	PF11976	0.530
LIG_SUMO_SIM_par_1	399	404	PF11976	0.421
LIG_SUMO_SIM_par_1	717	722	PF11976	0.438
LIG_TYR_ITIM	39	44	PF00017	0.490
LIG_WW_3	891	895	PF00397	0.565
MOD_CDK_SPxK_1	888	894	PF00069	0.608
MOD_CDK_SPxxK_3	1114	1121	PF00069	0.289
MOD_CK1_1	1060	1066	PF00069	0.348
MOD_CK1_1	1081	1087	PF00069	0.309
MOD_CK1_1	109	115	PF00069	0.484
MOD_CK1_1	1113	1119	PF00069	0.372
MOD_CK1_1	1226	1232	PF00069	0.508
MOD_CK1_1	177	183	PF00069	0.446
MOD_CK1_1	231	237	PF00069	0.488
MOD_CK1_1	243	249	PF00069	0.621
MOD_CK1_1	260	266	PF00069	0.350
MOD_CK1_1	3	9	PF00069	0.420
MOD_CK1_1	346	352	PF00069	0.562
MOD_CK1_1	357	363	PF00069	0.410
MOD_CK1_1	447	453	PF00069	0.523
MOD_CK1_1	525	531	PF00069	0.396
MOD_CK1_1	74	80	PF00069	0.548
MOD_CK1_1	766	772	PF00069	0.549
MOD_CK1_1	944	950	PF00069	0.624
MOD_CK2_1	1122	1128	PF00069	0.334
MOD_CK2_1	1233	1239	PF00069	0.395
MOD_CK2_1	129	135	PF00069	0.419
MOD_CK2_1	325	331	PF00069	0.496
MOD_CK2_1	603	609	PF00069	0.423
MOD_CK2_1	684	690	PF00069	0.565
MOD_GlcNHglycan	1058	1062	PF01048	0.358
MOD_GlcNHglycan	1112	1115	PF01048	0.331
MOD_GlcNHglycan	1175	1178	PF01048	0.309
MOD_GlcNHglycan	1181	1184	PF01048	0.309
MOD_GlcNHglycan	1195	1198	PF01048	0.183
MOD_GlcNHglycan	145	149	PF01048	0.511
MOD_GlcNHglycan	184	187	PF01048	0.514
MOD_GlcNHglycan	224	227	PF01048	0.582
MOD_GlcNHglycan	230	233	PF01048	0.439
MOD_GlcNHglycan	259	262	PF01048	0.616
MOD_GlcNHglycan	288	291	PF01048	0.506
MOD_GlcNHglycan	346	349	PF01048	0.597
MOD_GlcNHglycan	359	362	PF01048	0.386
MOD_GlcNHglycan	421	424	PF01048	0.336
MOD_GlcNHglycan	447	450	PF01048	0.640
MOD_GlcNHglycan	5	8	PF01048	0.369
MOD_GlcNHglycan	524	527	PF01048	0.364
MOD_GlcNHglycan	55	58	PF01048	0.458
MOD_GlcNHglycan	582	585	PF01048	0.489
MOD_GlcNHglycan	661	664	PF01048	0.630
MOD_GlcNHglycan	68	71	PF01048	0.436
MOD_GlcNHglycan	702	705	PF01048	0.514
MOD_GlcNHglycan	707	710	PF01048	0.557
MOD_GlcNHglycan	754	757	PF01048	0.548
MOD_GSK3_1	1041	1048	PF00069	0.309
MOD_GSK3_1	105	112	PF00069	0.527
MOD_GSK3_1	1053	1060	PF00069	0.309
MOD_GSK3_1	1081	1088	PF00069	0.265
MOD_GSK3_1	1109	1116	PF00069	0.316
MOD_GSK3_1	1193	1200	PF00069	0.309
MOD_GSK3_1	1251	1258	PF00069	0.504
MOD_GSK3_1	144	151	PF00069	0.579
MOD_GSK3_1	231	238	PF00069	0.453
MOD_GSK3_1	240	247	PF00069	0.529
MOD_GSK3_1	251	258	PF00069	0.525
MOD_GSK3_1	286	293	PF00069	0.420
MOD_GSK3_1	309	316	PF00069	0.654
MOD_GSK3_1	343	350	PF00069	0.521
MOD_GSK3_1	440	447	PF00069	0.707
MOD_GSK3_1	53	60	PF00069	0.429
MOD_GSK3_1	572	579	PF00069	0.462
MOD_GSK3_1	61	68	PF00069	0.429
MOD_GSK3_1	659	666	PF00069	0.639
MOD_N-GLC_1	752	757	PF02516	0.436
MOD_NEK2_1	1	6	PF00069	0.471
MOD_NEK2_1	115	120	PF00069	0.492
MOD_NEK2_1	1172	1177	PF00069	0.309
MOD_NEK2_1	1179	1184	PF00069	0.309
MOD_NEK2_1	221	226	PF00069	0.405
MOD_NEK2_1	235	240	PF00069	0.472
MOD_NEK2_1	325	330	PF00069	0.491
MOD_NEK2_1	344	349	PF00069	0.417
MOD_NEK2_1	474	479	PF00069	0.403
MOD_NEK2_1	522	527	PF00069	0.335
MOD_NEK2_1	53	58	PF00069	0.441
MOD_NEK2_1	545	550	PF00069	0.417
MOD_NEK2_1	577	582	PF00069	0.508
MOD_NEK2_1	66	71	PF00069	0.665
MOD_NEK2_1	697	702	PF00069	0.419
MOD_NEK2_1	719	724	PF00069	0.389
MOD_NEK2_1	772	777	PF00069	0.550
MOD_NEK2_1	8	13	PF00069	0.427
MOD_NEK2_1	942	947	PF00069	0.506
MOD_NEK2_2	1255	1260	PF00069	0.346
MOD_NEK2_2	912	917	PF00069	0.413
MOD_PIKK_1	1	7	PF00454	0.473
MOD_PIKK_1	1085	1091	PF00454	0.261
MOD_PIKK_1	1122	1128	PF00454	0.323
MOD_PIKK_1	1223	1229	PF00454	0.496
MOD_PIKK_1	347	353	PF00454	0.572
MOD_PIKK_1	558	564	PF00454	0.438
MOD_PIKK_1	57	63	PF00454	0.474
MOD_PIKK_1	684	690	PF00454	0.599
MOD_PIKK_1	763	769	PF00454	0.613
MOD_PKA_1	182	188	PF00069	0.466
MOD_PKA_2	1215	1221	PF00069	0.365
MOD_PKA_2	148	154	PF00069	0.446
MOD_PKA_2	182	188	PF00069	0.429
MOD_PKA_2	371	377	PF00069	0.345
MOD_PKA_2	426	432	PF00069	0.418
MOD_PKA_2	66	72	PF00069	0.547
MOD_PKA_2	697	703	PF00069	0.431
MOD_PKB_1	859	867	PF00069	0.450
MOD_Plk_1	1039	1045	PF00069	0.381
MOD_Plk_1	1057	1063	PF00069	0.183
MOD_Plk_1	129	135	PF00069	0.433
MOD_Plk_1	177	183	PF00069	0.430
MOD_Plk_1	325	331	PF00069	0.442
MOD_Plk_1	752	758	PF00069	0.475
MOD_Plk_1	942	948	PF00069	0.568
MOD_Plk_1	966	972	PF00069	0.421
MOD_Plk_2-3	1233	1239	PF00069	0.420
MOD_Plk_2-3	130	136	PF00069	0.490
MOD_Plk_4	1133	1139	PF00069	0.299
MOD_Plk_4	1164	1170	PF00069	0.389
MOD_Plk_4	1255	1261	PF00069	0.392
MOD_Plk_4	155	161	PF00069	0.412
MOD_Plk_4	184	190	PF00069	0.388
MOD_Plk_4	212	218	PF00069	0.356
MOD_Plk_4	231	237	PF00069	0.529
MOD_Plk_4	545	551	PF00069	0.476
MOD_Plk_4	572	578	PF00069	0.451
MOD_Plk_4	589	595	PF00069	0.383
MOD_Plk_4	673	679	PF00069	0.456
MOD_ProDKin_1	106	112	PF00069	0.637
MOD_ProDKin_1	1114	1120	PF00069	0.309
MOD_ProDKin_1	1161	1167	PF00069	0.334
MOD_ProDKin_1	245	251	PF00069	0.514
MOD_ProDKin_1	309	315	PF00069	0.572
MOD_ProDKin_1	362	368	PF00069	0.362
MOD_ProDKin_1	440	446	PF00069	0.497
MOD_ProDKin_1	447	453	PF00069	0.514
MOD_ProDKin_1	663	669	PF00069	0.726
MOD_ProDKin_1	74	80	PF00069	0.484
MOD_ProDKin_1	888	894	PF00069	0.608
MOD_ProDKin_1	987	993	PF00069	0.487
TRG_DiLeu_BaEn_1	1017	1022	PF01217	0.289
TRG_DiLeu_BaEn_1	25	30	PF01217	0.418
TRG_DiLeu_BaEn_1	412	417	PF01217	0.422
TRG_DiLeu_BaEn_1	690	695	PF01217	0.495
TRG_DiLeu_BaLyEn_6	1063	1068	PF01217	0.253
TRG_DiLeu_BaLyEn_6	1119	1124	PF01217	0.328
TRG_DiLeu_BaLyEn_6	306	311	PF01217	0.458
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.444
TRG_DiLeu_BaLyEn_6	396	401	PF01217	0.429
TRG_DiLeu_BaLyEn_6	526	531	PF01217	0.414
TRG_DiLeu_BaLyEn_6	549	554	PF01217	0.406
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.309
TRG_ENDOCYTIC_2	1155	1158	PF00928	0.309
TRG_ENDOCYTIC_2	1185	1188	PF00928	0.309
TRG_ENDOCYTIC_2	41	44	PF00928	0.462
TRG_ENDOCYTIC_2	546	549	PF00928	0.341
TRG_ENDOCYTIC_2	986	989	PF00928	0.500
TRG_ER_diArg_1	1120	1122	PF00400	0.289
TRG_ER_diArg_1	181	183	PF00400	0.493
TRG_ER_diArg_1	204	206	PF00400	0.529
TRG_ER_diArg_1	217	219	PF00400	0.305
TRG_ER_diArg_1	281	284	PF00400	0.436
TRG_ER_diArg_1	338	341	PF00400	0.449
TRG_ER_diArg_1	375	377	PF00400	0.354
TRG_ER_diArg_1	433	435	PF00400	0.455
TRG_ER_diArg_1	502	505	PF00400	0.474
TRG_ER_diArg_1	651	653	PF00400	0.538
TRG_ER_diArg_1	697	699	PF00400	0.406
TRG_ER_diArg_1	797	800	PF00400	0.498
TRG_ER_diArg_1	858	861	PF00400	0.428
TRG_Pf-PMV_PEXEL_1	10	14	PF00026	0.451
TRG_Pf-PMV_PEXEL_1	1121	1126	PF00026	0.320
TRG_Pf-PMV_PEXEL_1	762	767	PF00026	0.602
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.463
TRG_Pf-PMV_PEXEL_1	987	992	PF00026	0.487

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCC3	Leptomonas seymouri	40%	98%
A4HYZ7	Leishmania infantum	99%	100%
E9AIL6	Leishmania braziliensis	75%	100%
E9AUU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QCN4	Leishmania major	91%	100%