SEC7 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IDQ3_LEIDO

TriTrypDb:

LdBPK_161120.1 , LdCL_160016200 , LDHU3_16.1360

Length:

639

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IDQ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDQ3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	381	385	PF00656	0.725
CLV_C14_Caspase3-7	386	390	PF00656	0.683
CLV_C14_Caspase3-7	427	431	PF00656	0.685
CLV_C14_Caspase3-7	438	442	PF00656	0.607
CLV_NRD_NRD_1	173	175	PF00675	0.690
CLV_NRD_NRD_1	186	188	PF00675	0.582
CLV_NRD_NRD_1	259	261	PF00675	0.660
CLV_NRD_NRD_1	285	287	PF00675	0.723
CLV_NRD_NRD_1	303	305	PF00675	0.629
CLV_NRD_NRD_1	334	336	PF00675	0.542
CLV_NRD_NRD_1	58	60	PF00675	0.729
CLV_NRD_NRD_1	605	607	PF00675	0.783
CLV_NRD_NRD_1	622	624	PF00675	0.608
CLV_PCSK_FUR_1	257	261	PF00082	0.637
CLV_PCSK_FUR_1	270	274	PF00082	0.714
CLV_PCSK_FUR_1	55	59	PF00082	0.696
CLV_PCSK_KEX2_1	173	175	PF00082	0.690
CLV_PCSK_KEX2_1	186	188	PF00082	0.582
CLV_PCSK_KEX2_1	259	261	PF00082	0.689
CLV_PCSK_KEX2_1	272	274	PF00082	0.665
CLV_PCSK_KEX2_1	285	287	PF00082	0.649
CLV_PCSK_KEX2_1	303	305	PF00082	0.629
CLV_PCSK_KEX2_1	334	336	PF00082	0.542
CLV_PCSK_KEX2_1	519	521	PF00082	0.667
CLV_PCSK_KEX2_1	57	59	PF00082	0.697
CLV_PCSK_KEX2_1	605	607	PF00082	0.680
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.725
CLV_PCSK_PC1ET2_1	519	521	PF00082	0.698
CLV_PCSK_SKI1_1	158	162	PF00082	0.660
CLV_PCSK_SKI1_1	533	537	PF00082	0.740
DEG_SCF_TRCP1_1	614	620	PF00400	0.670
DOC_ANK_TNKS_1	572	579	PF00023	0.651
DOC_MAPK_DCC_7	118	126	PF00069	0.636
DOC_MAPK_gen_1	334	345	PF00069	0.676
DOC_MAPK_gen_1	605	611	PF00069	0.652
DOC_PP2B_LxvP_1	447	450	PF13499	0.702
DOC_PP2B_LxvP_1	586	589	PF13499	0.665
DOC_USP7_MATH_1	114	118	PF00917	0.828
DOC_USP7_MATH_1	284	288	PF00917	0.711
DOC_USP7_MATH_1	459	463	PF00917	0.767
DOC_USP7_MATH_2	243	249	PF00917	0.672
DOC_USP7_UBL2_3	519	523	PF12436	0.748
DOC_USP7_UBL2_3	76	80	PF12436	0.606
DOC_WW_Pin1_4	117	122	PF00397	0.662
DOC_WW_Pin1_4	180	185	PF00397	0.602
DOC_WW_Pin1_4	587	592	PF00397	0.748
LIG_14-3-3_CanoR_1	107	113	PF00244	0.746
LIG_14-3-3_CanoR_1	173	182	PF00244	0.722
LIG_14-3-3_CanoR_1	229	236	PF00244	0.604
LIG_14-3-3_CanoR_1	285	295	PF00244	0.730
LIG_14-3-3_CanoR_1	3	12	PF00244	0.663
LIG_14-3-3_CanoR_1	464	468	PF00244	0.702
LIG_14-3-3_CanoR_1	538	544	PF00244	0.800
LIG_14-3-3_CanoR_1	579	589	PF00244	0.686
LIG_14-3-3_CanoR_1	605	612	PF00244	0.738
LIG_14-3-3_CterR_2	636	639	PF00244	0.620
LIG_CtBP_PxDLS_1	131	135	PF00389	0.555
LIG_deltaCOP1_diTrp_1	393	401	PF00928	0.682
LIG_FHA_1	482	488	PF00498	0.741
LIG_FHA_1	547	553	PF00498	0.704
LIG_FHA_1	556	562	PF00498	0.593
LIG_FHA_2	264	270	PF00498	0.739
LIG_GSK3_LRP6_1	587	593	PF00069	0.670
LIG_Integrin_isoDGR_2	621	623	PF01839	0.672
LIG_LIR_Apic_2	135	141	PF02991	0.666
LIG_LIR_Nem_3	71	77	PF02991	0.656
LIG_SH2_CRK	138	142	PF00017	0.597
LIG_SH2_GRB2like	418	421	PF00017	0.666
LIG_SH2_STAP1	77	81	PF00017	0.628
LIG_SH2_STAT3	264	267	PF00017	0.696
LIG_SH3_1	163	169	PF00018	0.668
LIG_SH3_1	233	239	PF00018	0.743
LIG_SH3_1	96	102	PF00018	0.690
LIG_SH3_2	631	636	PF14604	0.703
LIG_SH3_3	163	169	PF00018	0.715
LIG_SH3_3	233	239	PF00018	0.720
LIG_SH3_3	28	34	PF00018	0.590
LIG_SH3_3	446	452	PF00018	0.715
LIG_SH3_3	469	475	PF00018	0.811
LIG_SH3_3	549	555	PF00018	0.708
LIG_SH3_3	557	563	PF00018	0.608
LIG_SH3_3	569	575	PF00018	0.486
LIG_SH3_3	582	588	PF00018	0.605
LIG_SH3_3	628	634	PF00018	0.708
LIG_SH3_3	8	14	PF00018	0.706
LIG_SH3_3	96	102	PF00018	0.690
LIG_SUMO_SIM_anti_2	42	48	PF11976	0.616
LIG_TRAF2_1	250	253	PF00917	0.611
LIG_TRFH_1	180	184	PF08558	0.670
LIG_WW_3	335	339	PF00397	0.588
MOD_CDC14_SPxK_1	183	186	PF00782	0.641
MOD_CDK_SPxK_1	180	186	PF00069	0.647
MOD_CDK_SPxxK_3	180	187	PF00069	0.599
MOD_CK1_1	117	123	PF00069	0.732
MOD_CK1_1	175	181	PF00069	0.650
MOD_CK1_1	247	253	PF00069	0.690
MOD_CK1_1	287	293	PF00069	0.713
MOD_CK1_1	442	448	PF00069	0.705
MOD_CK1_1	501	507	PF00069	0.707
MOD_CK1_1	545	551	PF00069	0.708
MOD_CK1_1	590	596	PF00069	0.807
MOD_CK1_1	6	12	PF00069	0.756
MOD_CK1_1	615	621	PF00069	0.692
MOD_CK2_1	247	253	PF00069	0.643
MOD_CK2_1	263	269	PF00069	0.662
MOD_CK2_1	604	610	PF00069	0.729
MOD_Cter_Amidation	171	174	PF01082	0.685
MOD_Cter_Amidation	184	187	PF01082	0.582
MOD_Cter_Amidation	621	624	PF01082	0.671
MOD_GlcNHglycan	134	137	PF01048	0.693
MOD_GlcNHglycan	177	180	PF01048	0.596
MOD_GlcNHglycan	197	200	PF01048	0.705
MOD_GlcNHglycan	211	216	PF01048	0.595
MOD_GlcNHglycan	261	264	PF01048	0.684
MOD_GlcNHglycan	28	31	PF01048	0.644
MOD_GlcNHglycan	304	307	PF01048	0.728
MOD_GlcNHglycan	312	315	PF01048	0.617
MOD_GlcNHglycan	35	38	PF01048	0.579
MOD_GlcNHglycan	564	567	PF01048	0.648
MOD_GlcNHglycan	582	585	PF01048	0.642
MOD_GlcNHglycan	613	617	PF01048	0.709
MOD_GlcNHglycan	88	91	PF01048	0.704
MOD_GSK3_1	2	9	PF00069	0.714
MOD_GSK3_1	201	208	PF00069	0.640
MOD_GSK3_1	255	262	PF00069	0.699
MOD_GSK3_1	459	466	PF00069	0.714
MOD_GSK3_1	497	504	PF00069	0.710
MOD_GSK3_1	539	546	PF00069	0.724
MOD_GSK3_1	86	93	PF00069	0.654
MOD_LATS_1	156	162	PF00433	0.661
MOD_LATS_1	480	486	PF00433	0.603
MOD_N-GLC_1	255	260	PF02516	0.743
MOD_N-GLC_1	536	541	PF02516	0.726
MOD_N-GLC_1	546	551	PF02516	0.602
MOD_NEK2_1	463	468	PF00069	0.765
MOD_NEK2_1	536	541	PF00069	0.679
MOD_NEK2_1	612	617	PF00069	0.679
MOD_NEK2_1	75	80	PF00069	0.510
MOD_PIKK_1	12	18	PF00454	0.610
MOD_PIKK_1	247	253	PF00454	0.671
MOD_PIKK_1	263	269	PF00454	0.578
MOD_PIKK_1	473	479	PF00454	0.695
MOD_PIKK_1	501	507	PF00454	0.711
MOD_PIKK_1	593	599	PF00454	0.717
MOD_PIKK_1	604	610	PF00454	0.639
MOD_PKA_1	173	179	PF00069	0.665
MOD_PKA_1	259	265	PF00069	0.603
MOD_PKA_1	285	291	PF00069	0.681
MOD_PKA_1	522	528	PF00069	0.702
MOD_PKA_2	106	112	PF00069	0.747
MOD_PKA_2	172	178	PF00069	0.764
MOD_PKA_2	2	8	PF00069	0.675
MOD_PKA_2	228	234	PF00069	0.605
MOD_PKA_2	259	265	PF00069	0.603
MOD_PKA_2	284	290	PF00069	0.724
MOD_PKA_2	302	308	PF00069	0.559
MOD_PKA_2	362	368	PF00069	0.614
MOD_PKA_2	463	469	PF00069	0.697
MOD_PKA_2	481	487	PF00069	0.791
MOD_PKA_2	604	610	PF00069	0.769
MOD_PKB_1	257	265	PF00069	0.604
MOD_Plk_2-3	205	211	PF00069	0.647
MOD_Plk_4	539	545	PF00069	0.717
MOD_Plk_4	548	554	PF00069	0.614
MOD_ProDKin_1	117	123	PF00069	0.660
MOD_ProDKin_1	180	186	PF00069	0.604
MOD_ProDKin_1	587	593	PF00069	0.751
MOD_SUMO_rev_2	515	525	PF00179	0.628
TRG_ER_diArg_1	257	260	PF00400	0.660
TRG_ER_diArg_1	284	286	PF00400	0.685
TRG_ER_diArg_1	334	336	PF00400	0.564
TRG_ER_diArg_1	56	59	PF00400	0.694
TRG_NLS_MonoExtC_3	454	459	PF00514	0.576
TRG_NLS_MonoExtN_4	452	459	PF00514	0.571
TRG_NLS_MonoExtN_4	520	527	PF00514	0.710

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H8N4	Leishmania braziliensis	51%	96%
A4HX04	Leishmania infantum	98%	99%
E9AQR7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%
Q4QEQ9	Leishmania major	85%	100%