Protein YIF1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Protein YIF1

Gene product:

protein transport protein YIF1, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IDN8_LEIDO

TriTrypDb:

LdBPK_201160.1 , LdCL_200016300 , LDHU3_20.1430

Length:

319

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0000139	Golgi membrane	5	11
GO:0005789	endoplasmic reticulum membrane	4	12
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	5	12
GO:0016020	membrane	2	12
GO:0030134	COPII-coated ER to Golgi transport vesicle	8	1
GO:0030135	coated vesicle	7	1
GO:0031090	organelle membrane	3	12
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	12

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Expansion

Sequence features

A0A3Q8IDN8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDN8

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	12
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	4	12
GO:0008104	protein localization	4	12
GO:0009987	cellular process	1	12
GO:0015031	protein transport	4	12
GO:0016192	vesicle-mediated transport	4	12
GO:0033036	macromolecule localization	2	12
GO:0045184	establishment of protein localization	3	12
GO:0046907	intracellular transport	3	12
GO:0048193	Golgi vesicle transport	5	12

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	81	83	PF00675	0.273
CLV_NRD_NRD_1	96	98	PF00675	0.207
CLV_PCSK_KEX2_1	81	83	PF00082	0.272
CLV_PCSK_PC1ET2_1	81	83	PF00082	0.278
CLV_PCSK_SKI1_1	241	245	PF00082	0.321
CLV_PCSK_SKI1_1	297	301	PF00082	0.368
DEG_Nend_UBRbox_3	1	3	PF02207	0.763
DOC_CKS1_1	1	6	PF01111	0.706
DOC_MAPK_gen_1	81	87	PF00069	0.443
DOC_MAPK_MEF2A_6	241	249	PF00069	0.334

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEI6	Leptomonas seymouri	61%	99%
A0A0S4KG55	Bodo saltans	34%	100%
A0A1X0NW97	Trypanosomatidae	39%	100%
A0A3R7RL55	Trypanosoma rangeli	35%	100%
A4HYV6	Leishmania infantum	100%	100%
C9ZID7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9AIG3	Leishmania braziliensis	85%	100%
E9AUQ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4FZQ0	Xenopus laevis	24%	100%
Q4QCT2	Leishmania major	93%	100%

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