Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IDN0_LEIDO

TriTrypDb:

LdBPK_260070.1 , LdCL_260005600 , LDHU3_26.0100

Length:

302

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IDN0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDN0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.710
CLV_NRD_NRD_1	120	122	PF00675	0.560
CLV_NRD_NRD_1	187	189	PF00675	0.781
CLV_NRD_NRD_1	242	244	PF00675	0.808
CLV_NRD_NRD_1	43	45	PF00675	0.646
CLV_NRD_NRD_1	81	83	PF00675	0.676
CLV_PCSK_KEX2_1	113	115	PF00082	0.710
CLV_PCSK_KEX2_1	187	189	PF00082	0.781
CLV_PCSK_KEX2_1	242	244	PF00082	0.808
CLV_PCSK_KEX2_1	42	44	PF00082	0.643
CLV_PCSK_KEX2_1	80	82	PF00082	0.678
CLV_PCSK_SKI1_1	114	118	PF00082	0.621
CLV_PCSK_SKI1_1	219	223	PF00082	0.607
CLV_PCSK_SKI1_1	22	26	PF00082	0.538
CLV_PCSK_SKI1_1	283	287	PF00082	0.825
DEG_APCC_DBOX_1	113	121	PF00400	0.683
DEG_APCC_DBOX_1	21	29	PF00400	0.582
DEG_COP1_1	250	260	PF00400	0.744
DEG_Nend_Nbox_1	1	3	PF02207	0.665
DOC_MAPK_MEF2A_6	151	158	PF00069	0.572
DOC_USP7_MATH_1	157	161	PF00917	0.795
DOC_USP7_MATH_1	17	21	PF00917	0.679
DOC_USP7_MATH_1	225	229	PF00917	0.741
DOC_WW_Pin1_4	15	20	PF00397	0.663
DOC_WW_Pin1_4	150	155	PF00397	0.734
DOC_WW_Pin1_4	161	166	PF00397	0.668
DOC_WW_Pin1_4	219	224	PF00397	0.641
DOC_WW_Pin1_4	245	250	PF00397	0.751
DOC_WW_Pin1_4	290	295	PF00397	0.843
DOC_WW_Pin1_4	46	51	PF00397	0.628
LIG_14-3-3_CanoR_1	81	87	PF00244	0.576
LIG_BRCT_BRCA1_1	185	189	PF00533	0.703
LIG_FHA_1	147	153	PF00498	0.668
LIG_FHA_1	95	101	PF00498	0.623
LIG_FHA_2	47	53	PF00498	0.518
LIG_FHA_2	94	100	PF00498	0.651
LIG_GBD_Chelix_1	66	74	PF00786	0.450
LIG_Integrin_RGD_1	243	245	PF01839	0.718
LIG_LIR_Apic_2	207	213	PF02991	0.630
LIG_LIR_Gen_1	196	205	PF02991	0.693
LIG_LIR_Nem_3	186	192	PF02991	0.671
LIG_LIR_Nem_3	196	202	PF02991	0.717
LIG_LIR_Nem_3	6	12	PF02991	0.666
LIG_Pex14_1	210	214	PF04695	0.685
LIG_RPA_C_Fungi	57	69	PF08784	0.475
LIG_SH2_CRK	89	93	PF00017	0.602
LIG_SH2_STAP1	89	93	PF00017	0.584
LIG_SH3_3	113	119	PF00018	0.685
LIG_SH3_3	199	205	PF00018	0.770
LIG_SH3_3	221	227	PF00018	0.644
LIG_TRAF2_1	250	253	PF00917	0.751
LIG_WRC_WIRS_1	226	231	PF05994	0.625
MOD_CDK_SPxxK_3	15	22	PF00069	0.594
MOD_CK1_1	160	166	PF00069	0.565
MOD_CK1_1	273	279	PF00069	0.702
MOD_CK1_1	36	42	PF00069	0.577
MOD_CK2_1	105	111	PF00069	0.649
MOD_CK2_1	17	23	PF00069	0.684
MOD_CK2_1	247	253	PF00069	0.750
MOD_CK2_1	48	54	PF00069	0.557
MOD_GlcNHglycan	140	143	PF01048	0.608
MOD_GlcNHglycan	159	162	PF01048	0.629
MOD_GlcNHglycan	249	252	PF01048	0.750
MOD_GlcNHglycan	280	283	PF01048	0.654
MOD_GlcNHglycan	35	38	PF01048	0.480
MOD_GSK3_1	101	108	PF00069	0.726
MOD_GSK3_1	146	153	PF00069	0.780
MOD_GSK3_1	157	164	PF00069	0.613
MOD_GSK3_1	263	270	PF00069	0.766
MOD_GSK3_1	273	280	PF00069	0.627
MOD_GSK3_1	290	297	PF00069	0.707
MOD_GSK3_1	32	39	PF00069	0.671
MOD_N-GLC_1	15	20	PF02516	0.633
MOD_N-GLC_1	169	174	PF02516	0.748
MOD_N-GLC_1	270	275	PF02516	0.801
MOD_NEK2_1	101	106	PF00069	0.713
MOD_PIKK_1	101	107	PF00454	0.624
MOD_PKB_1	80	88	PF00069	0.662
MOD_Plk_1	169	175	PF00069	0.725
MOD_Plk_4	132	138	PF00069	0.563
MOD_Plk_4	170	176	PF00069	0.612
MOD_Plk_4	225	231	PF00069	0.657
MOD_Plk_4	256	262	PF00069	0.787
MOD_Plk_4	88	94	PF00069	0.539
MOD_ProDKin_1	15	21	PF00069	0.657
MOD_ProDKin_1	150	156	PF00069	0.736
MOD_ProDKin_1	161	167	PF00069	0.665
MOD_ProDKin_1	219	225	PF00069	0.642
MOD_ProDKin_1	245	251	PF00069	0.749
MOD_ProDKin_1	290	296	PF00069	0.843
MOD_ProDKin_1	46	52	PF00069	0.623
TRG_ENDOCYTIC_2	199	202	PF00928	0.679
TRG_ENDOCYTIC_2	89	92	PF00928	0.604
TRG_ER_diArg_1	113	115	PF00400	0.632
TRG_ER_diArg_1	187	189	PF00400	0.791
TRG_ER_diArg_1	205	208	PF00400	0.644
TRG_ER_diArg_1	241	243	PF00400	0.807
TRG_ER_diArg_1	42	44	PF00400	0.642
TRG_ER_diArg_1	80	82	PF00400	0.614
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.580
TRG_Pf-PMV_PEXEL_1	68	72	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1M0	Leptomonas seymouri	41%	87%
A4HEL4	Leishmania braziliensis	63%	100%
A4I1U5	Leishmania infantum	99%	100%
E9AXY9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q9I5	Leishmania major	89%	100%