RNA-binding, protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding, protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IDF9_LEIDO

TriTrypDb:

LdBPK_323670.1 , LdCL_320042600 , LDHU3_32.4640

Length:

565

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IDF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDF9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	2	6	PF00656	0.448
CLV_C14_Caspase3-7	429	433	PF00656	0.797
CLV_C14_Caspase3-7	439	443	PF00656	0.541
CLV_NRD_NRD_1	341	343	PF00675	0.458
CLV_NRD_NRD_1	377	379	PF00675	0.532
CLV_NRD_NRD_1	386	388	PF00675	0.527
CLV_NRD_NRD_1	389	391	PF00675	0.504
CLV_NRD_NRD_1	394	396	PF00675	0.532
CLV_NRD_NRD_1	58	60	PF00675	0.565
CLV_NRD_NRD_1	74	76	PF00675	0.612
CLV_PCSK_FUR_1	377	381	PF00082	0.494
CLV_PCSK_FUR_1	382	386	PF00082	0.500
CLV_PCSK_KEX2_1	341	343	PF00082	0.458
CLV_PCSK_KEX2_1	376	378	PF00082	0.529
CLV_PCSK_KEX2_1	379	381	PF00082	0.527
CLV_PCSK_KEX2_1	384	386	PF00082	0.543
CLV_PCSK_KEX2_1	393	395	PF00082	0.529
CLV_PCSK_KEX2_1	58	60	PF00082	0.581
CLV_PCSK_KEX2_1	74	76	PF00082	0.612
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.494
CLV_PCSK_PC1ET2_1	379	381	PF00082	0.489
CLV_PCSK_PC1ET2_1	393	395	PF00082	0.483
CLV_PCSK_PC7_1	380	386	PF00082	0.555
CLV_PCSK_PC7_1	390	396	PF00082	0.432
CLV_PCSK_SKI1_1	197	201	PF00082	0.608
CLV_PCSK_SKI1_1	342	346	PF00082	0.482
CLV_PCSK_SKI1_1	390	394	PF00082	0.497
CLV_PCSK_SKI1_1	395	399	PF00082	0.488
CLV_PCSK_SKI1_1	470	474	PF00082	0.283
CLV_PCSK_SKI1_1	50	54	PF00082	0.465
CLV_PCSK_SKI1_1	82	86	PF00082	0.472
DEG_APCC_DBOX_1	49	57	PF00400	0.447
DEG_APCC_DBOX_1	81	89	PF00400	0.478
DEG_COP1_1	445	455	PF00400	0.495
DEG_Nend_UBRbox_2	1	3	PF02207	0.517
DEG_SPOP_SBC_1	424	428	PF00917	0.697
DOC_CDC14_PxL_1	17	25	PF14671	0.582
DOC_CKS1_1	115	120	PF01111	0.615
DOC_CKS1_1	155	160	PF01111	0.548
DOC_CYCLIN_RxL_1	194	205	PF00134	0.618
DOC_MAPK_gen_1	390	400	PF00069	0.578
DOC_MAPK_MEF2A_6	312	319	PF00069	0.379
DOC_MAPK_MEF2A_6	46	53	PF00069	0.442
DOC_PP1_RVXF_1	195	202	PF00149	0.601
DOC_PP4_FxxP_1	201	204	PF00568	0.612
DOC_USP7_MATH_1	126	130	PF00917	0.660
DOC_USP7_MATH_1	169	173	PF00917	0.663
DOC_USP7_MATH_1	355	359	PF00917	0.619
DOC_USP7_MATH_1	367	371	PF00917	0.588
DOC_USP7_MATH_1	420	424	PF00917	0.720
DOC_WW_Pin1_4	114	119	PF00397	0.602
DOC_WW_Pin1_4	130	135	PF00397	0.491
DOC_WW_Pin1_4	147	152	PF00397	0.610
DOC_WW_Pin1_4	154	159	PF00397	0.642
DOC_WW_Pin1_4	171	176	PF00397	0.627
DOC_WW_Pin1_4	249	254	PF00397	0.405
DOC_WW_Pin1_4	405	410	PF00397	0.605
DOC_WW_Pin1_4	433	438	PF00397	0.605
LIG_14-3-3_CanoR_1	483	487	PF00244	0.477
LIG_14-3-3_CanoR_1	500	505	PF00244	0.489
LIG_14-3-3_CanoR_1	520	525	PF00244	0.493
LIG_14-3-3_CanoR_1	545	550	PF00244	0.556
LIG_14-3-3_CanoR_1	97	105	PF00244	0.621
LIG_BRCT_BRCA1_1	489	493	PF00533	0.477
LIG_DLG_GKlike_1	520	528	PF00625	0.584
LIG_eIF4E_1	519	525	PF01652	0.477
LIG_FHA_1	155	161	PF00498	0.571
LIG_FHA_1	219	225	PF00498	0.443
LIG_FHA_1	269	275	PF00498	0.404
LIG_FHA_1	284	290	PF00498	0.381
LIG_FHA_1	328	334	PF00498	0.493
LIG_FHA_1	492	498	PF00498	0.473
LIG_FHA_1	93	99	PF00498	0.582
LIG_FHA_2	148	154	PF00498	0.650
LIG_FHA_2	267	273	PF00498	0.443
LIG_FHA_2	462	468	PF00498	0.485
LIG_FHA_2	476	482	PF00498	0.477
LIG_FHA_2	556	562	PF00498	0.576
LIG_IBAR_NPY_1	240	242	PF08397	0.416
LIG_LIR_Nem_3	282	288	PF02991	0.364
LIG_LIR_Nem_3	517	522	PF02991	0.490
LIG_LIR_Nem_3	89	93	PF02991	0.565
LIG_NRBOX	468	474	PF00104	0.477
LIG_PCNA_PIPBox_1	81	90	PF02747	0.563
LIG_PDZ_Class_2	560	565	PF00595	0.525
LIG_PDZ_Wminus1_1	563	565	PF00595	0.510
LIG_PTB_Apo_2	237	244	PF02174	0.400
LIG_PTB_Apo_2	513	520	PF02174	0.535
LIG_PTB_Phospho_1	513	519	PF10480	0.535
LIG_Rb_pABgroove_1	18	26	PF01858	0.535
LIG_REV1ctd_RIR_1	198	203	PF16727	0.520
LIG_RPA_C_Fungi	373	385	PF08784	0.495
LIG_SH2_CRK	38	42	PF00017	0.588
LIG_SH2_CRK	476	480	PF00017	0.315
LIG_SH2_CRK	522	526	PF00017	0.383
LIG_SH2_NCK_1	522	526	PF00017	0.464
LIG_SH2_STAP1	24	28	PF00017	0.495
LIG_SH2_STAP1	285	289	PF00017	0.319
LIG_SH2_STAT5	225	228	PF00017	0.445
LIG_SH2_STAT5	242	245	PF00017	0.524
LIG_SH2_STAT5	262	265	PF00017	0.542
LIG_SH2_STAT5	285	288	PF00017	0.410
LIG_SH2_STAT5	310	313	PF00017	0.477
LIG_SH3_3	176	182	PF00018	0.643
LIG_SUMO_SIM_anti_2	531	537	PF11976	0.457
LIG_SUMO_SIM_par_1	291	298	PF11976	0.356
LIG_SUMO_SIM_par_1	50	55	PF11976	0.461
LIG_SUMO_SIM_par_1	534	540	PF11976	0.486
LIG_TRAF2_1	410	413	PF00917	0.677
LIG_TRAF2_1	503	506	PF00917	0.315
LIG_TRAF2_2	118	123	PF00917	0.547
MOD_CDK_SPK_2	154	159	PF00069	0.607
MOD_CDK_SPxK_1	135	141	PF00069	0.636
MOD_CDK_SPxxK_3	171	178	PF00069	0.696
MOD_CDK_SPxxK_3	249	256	PF00069	0.391
MOD_CK1_1	174	180	PF00069	0.701
MOD_CK1_1	280	286	PF00069	0.439
MOD_CK1_1	358	364	PF00069	0.583
MOD_CK1_1	407	413	PF00069	0.630
MOD_CK1_1	423	429	PF00069	0.608
MOD_CK1_1	430	436	PF00069	0.632
MOD_CK1_1	523	529	PF00069	0.445
MOD_CK1_1	99	105	PF00069	0.593
MOD_CK2_1	108	114	PF00069	0.597
MOD_CK2_1	147	153	PF00069	0.792
MOD_CK2_1	266	272	PF00069	0.440
MOD_CK2_1	407	413	PF00069	0.608
MOD_CK2_1	475	481	PF00069	0.315
MOD_CK2_1	500	506	PF00069	0.341
MOD_CK2_1	555	561	PF00069	0.551
MOD_CK2_1	86	92	PF00069	0.543
MOD_GlcNHglycan	126	129	PF01048	0.649
MOD_GlcNHglycan	165	168	PF01048	0.684
MOD_GlcNHglycan	169	172	PF01048	0.674
MOD_GlcNHglycan	282	285	PF01048	0.490
MOD_GlcNHglycan	359	363	PF01048	0.639
MOD_GlcNHglycan	370	373	PF01048	0.547
MOD_GlcNHglycan	422	425	PF01048	0.768
MOD_GlcNHglycan	442	445	PF01048	0.535
MOD_GlcNHglycan	487	492	PF01048	0.315
MOD_GlcNHglycan	525	528	PF01048	0.364
MOD_GlcNHglycan	62	65	PF01048	0.711
MOD_GSK3_1	126	133	PF00069	0.701
MOD_GSK3_1	145	152	PF00069	0.602
MOD_GSK3_1	163	170	PF00069	0.630
MOD_GSK3_1	189	196	PF00069	0.664
MOD_GSK3_1	403	410	PF00069	0.614
MOD_GSK3_1	420	427	PF00069	0.547
MOD_GSK3_1	428	435	PF00069	0.586
MOD_GSK3_1	436	443	PF00069	0.690
MOD_GSK3_1	487	494	PF00069	0.327
MOD_GSK3_1	60	67	PF00069	0.679
MOD_GSK3_1	92	99	PF00069	0.660
MOD_N-GLC_1	508	513	PF02516	0.208
MOD_N-GLC_1	60	65	PF02516	0.635
MOD_NEK2_1	218	223	PF00069	0.455
MOD_NEK2_1	266	271	PF00069	0.461
MOD_NEK2_1	37	42	PF00069	0.508
MOD_NEK2_1	508	513	PF00069	0.345
MOD_NEK2_1	60	65	PF00069	0.584
MOD_PIKK_1	116	122	PF00454	0.618
MOD_PIKK_1	26	32	PF00454	0.593
MOD_PK_1	393	399	PF00069	0.582
MOD_PK_1	500	506	PF00069	0.370
MOD_PKA_1	393	399	PF00069	0.582
MOD_PKA_2	167	173	PF00069	0.710
MOD_PKA_2	202	208	PF00069	0.618
MOD_PKA_2	393	399	PF00069	0.672
MOD_PKA_2	482	488	PF00069	0.315
MOD_PKA_2	96	102	PF00069	0.602
MOD_Plk_1	235	241	PF00069	0.431
MOD_Plk_1	555	561	PF00069	0.498
MOD_Plk_4	283	289	PF00069	0.385
MOD_Plk_4	514	520	PF00069	0.343
MOD_ProDKin_1	114	120	PF00069	0.606
MOD_ProDKin_1	130	136	PF00069	0.491
MOD_ProDKin_1	147	153	PF00069	0.611
MOD_ProDKin_1	154	160	PF00069	0.641
MOD_ProDKin_1	171	177	PF00069	0.625
MOD_ProDKin_1	249	255	PF00069	0.404
MOD_ProDKin_1	405	411	PF00069	0.606
MOD_ProDKin_1	433	439	PF00069	0.603
TRG_DiLeu_BaEn_4	505	511	PF01217	0.395
TRG_DiLeu_BaLyEn_6	100	105	PF01217	0.589
TRG_ENDOCYTIC_2	225	228	PF00928	0.445
TRG_ENDOCYTIC_2	24	27	PF00928	0.482
TRG_ENDOCYTIC_2	246	249	PF00928	0.402
TRG_ENDOCYTIC_2	34	37	PF00928	0.517
TRG_ENDOCYTIC_2	38	41	PF00928	0.509
TRG_ENDOCYTIC_2	476	479	PF00928	0.315
TRG_ENDOCYTIC_2	522	525	PF00928	0.392
TRG_ER_diArg_1	340	342	PF00400	0.437
TRG_ER_diArg_1	377	380	PF00400	0.496
TRG_ER_diArg_1	382	385	PF00400	0.501
TRG_ER_diArg_1	58	60	PF00400	0.581
TRG_ER_diArg_1	74	76	PF00400	0.612
TRG_NLS_Bipartite_1	376	397	PF00514	0.489
TRG_NLS_MonoExtC_3	377	382	PF00514	0.503
TRG_NLS_MonoExtN_4	376	383	PF00514	0.492
TRG_NLS_MonoExtN_4	390	397	PF00514	0.483

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAT8	Leptomonas seymouri	53%	100%
A4HKZ0	Leishmania braziliensis	79%	99%
A4I8H1	Leishmania infantum	99%	100%
E9B3D1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q4S5	Leishmania major	93%	100%