Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IDF6_LEIDO

TriTrypDb:

LdBPK_271760.1 , LdCL_270024800 , LDHU3_27.2710

Length:

864

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IDF6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IDF6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.674
CLV_C14_Caspase3-7	226	230	PF00656	0.711
CLV_C14_Caspase3-7	380	384	PF00656	0.719
CLV_C14_Caspase3-7	463	467	PF00656	0.637
CLV_NRD_NRD_1	141	143	PF00675	0.732
CLV_NRD_NRD_1	163	165	PF00675	0.646
CLV_NRD_NRD_1	203	205	PF00675	0.778
CLV_NRD_NRD_1	213	215	PF00675	0.587
CLV_NRD_NRD_1	24	26	PF00675	0.701
CLV_NRD_NRD_1	284	286	PF00675	0.595
CLV_NRD_NRD_1	393	395	PF00675	0.743
CLV_NRD_NRD_1	472	474	PF00675	0.618
CLV_NRD_NRD_1	806	808	PF00675	0.736
CLV_PCSK_FUR_1	139	143	PF00082	0.733
CLV_PCSK_FUR_1	161	165	PF00082	0.638
CLV_PCSK_FUR_1	470	474	PF00082	0.619
CLV_PCSK_KEX2_1	141	143	PF00082	0.732
CLV_PCSK_KEX2_1	163	165	PF00082	0.646
CLV_PCSK_KEX2_1	203	205	PF00082	0.759
CLV_PCSK_KEX2_1	24	26	PF00082	0.701
CLV_PCSK_KEX2_1	271	273	PF00082	0.655
CLV_PCSK_KEX2_1	277	279	PF00082	0.547
CLV_PCSK_KEX2_1	284	286	PF00082	0.595
CLV_PCSK_KEX2_1	472	474	PF00082	0.618
CLV_PCSK_KEX2_1	806	808	PF00082	0.806
CLV_PCSK_PC1ET2_1	271	273	PF00082	0.655
CLV_PCSK_PC1ET2_1	277	279	PF00082	0.547
CLV_PCSK_SKI1_1	103	107	PF00082	0.805
CLV_PCSK_SKI1_1	142	146	PF00082	0.687
CLV_PCSK_SKI1_1	181	185	PF00082	0.706
CLV_Separin_Metazoa	363	367	PF03568	0.646
CLV_Separin_Metazoa	579	583	PF03568	0.775
DEG_APCC_DBOX_1	83	91	PF00400	0.610
DEG_SCF_FBW7_1	323	330	PF00400	0.807
DEG_SCF_FBW7_1	659	666	PF00400	0.734
DEG_SPOP_SBC_1	347	351	PF00917	0.678
DEG_SPOP_SBC_1	740	744	PF00917	0.712
DEG_SPOP_SBC_1	798	802	PF00917	0.699
DOC_ANK_TNKS_1	319	326	PF00023	0.671
DOC_CKS1_1	37	42	PF01111	0.694
DOC_CKS1_1	660	665	PF01111	0.755
DOC_CKS1_1	92	97	PF01111	0.721
DOC_CYCLIN_RxL_1	366	378	PF00134	0.554
DOC_MAPK_gen_1	281	291	PF00069	0.617
DOC_MAPK_gen_1	82	89	PF00069	0.611
DOC_MAPK_MEF2A_6	284	291	PF00069	0.542
DOC_PP2B_LxvP_1	168	171	PF13499	0.726
DOC_PP2B_LxvP_1	90	93	PF13499	0.716
DOC_USP7_MATH_1	120	124	PF00917	0.824
DOC_USP7_MATH_1	194	198	PF00917	0.818
DOC_USP7_MATH_1	199	203	PF00917	0.742
DOC_USP7_MATH_1	266	270	PF00917	0.571
DOC_USP7_MATH_1	53	57	PF00917	0.771
DOC_USP7_MATH_1	533	537	PF00917	0.744
DOC_USP7_MATH_1	573	577	PF00917	0.686
DOC_USP7_MATH_1	599	603	PF00917	0.602
DOC_USP7_MATH_1	629	633	PF00917	0.783
DOC_USP7_MATH_1	649	653	PF00917	0.719
DOC_USP7_MATH_1	663	667	PF00917	0.660
DOC_USP7_MATH_1	669	673	PF00917	0.652
DOC_USP7_MATH_1	679	683	PF00917	0.569
DOC_USP7_MATH_1	7	11	PF00917	0.755
DOC_USP7_MATH_1	708	712	PF00917	0.691
DOC_USP7_MATH_1	778	782	PF00917	0.710
DOC_USP7_MATH_1	798	802	PF00917	0.570
DOC_WW_Pin1_4	170	175	PF00397	0.777
DOC_WW_Pin1_4	18	23	PF00397	0.765
DOC_WW_Pin1_4	181	186	PF00397	0.628
DOC_WW_Pin1_4	192	197	PF00397	0.587
DOC_WW_Pin1_4	32	37	PF00397	0.595
DOC_WW_Pin1_4	323	328	PF00397	0.808
DOC_WW_Pin1_4	348	353	PF00397	0.778
DOC_WW_Pin1_4	480	485	PF00397	0.764
DOC_WW_Pin1_4	501	506	PF00397	0.685
DOC_WW_Pin1_4	527	532	PF00397	0.763
DOC_WW_Pin1_4	607	612	PF00397	0.656
DOC_WW_Pin1_4	659	664	PF00397	0.780
DOC_WW_Pin1_4	691	696	PF00397	0.736
DOC_WW_Pin1_4	704	709	PF00397	0.600
DOC_WW_Pin1_4	741	746	PF00397	0.762
DOC_WW_Pin1_4	76	81	PF00397	0.724
DOC_WW_Pin1_4	800	805	PF00397	0.815
DOC_WW_Pin1_4	91	96	PF00397	0.788
LIG_14-3-3_CanoR_1	141	150	PF00244	0.690
LIG_14-3-3_CanoR_1	222	228	PF00244	0.681
LIG_14-3-3_CanoR_1	235	239	PF00244	0.524
LIG_14-3-3_CanoR_1	284	288	PF00244	0.594
LIG_14-3-3_CanoR_1	510	519	PF00244	0.627
LIG_14-3-3_CanoR_1	648	654	PF00244	0.742
LIG_14-3-3_CanoR_1	697	705	PF00244	0.615
LIG_14-3-3_CanoR_1	84	90	PF00244	0.624
LIG_AP2alpha_1	792	796	PF02296	0.713
LIG_AP2alpha_2	69	71	PF02296	0.736
LIG_BIR_III_2	193	197	PF00653	0.677
LIG_BIR_III_2	50	54	PF00653	0.657
LIG_BIR_III_4	302	306	PF00653	0.473
LIG_CSL_BTD_1	352	355	PF09270	0.602
LIG_deltaCOP1_diTrp_1	430	438	PF00928	0.711
LIG_deltaCOP1_diTrp_1	783	786	PF00928	0.713
LIG_FHA_1	184	190	PF00498	0.812
LIG_FHA_1	235	241	PF00498	0.583
LIG_FHA_1	502	508	PF00498	0.643
LIG_FHA_1	515	521	PF00498	0.526
LIG_FHA_1	548	554	PF00498	0.812
LIG_FHA_1	589	595	PF00498	0.742
LIG_FHA_1	803	809	PF00498	0.673
LIG_FHA_1	84	90	PF00498	0.756
LIG_FHA_2	188	194	PF00498	0.613
LIG_FHA_2	224	230	PF00498	0.709
LIG_FHA_2	314	320	PF00498	0.808
LIG_FHA_2	341	347	PF00498	0.676
LIG_FHA_2	623	629	PF00498	0.838
LIG_FHA_2	825	831	PF00498	0.744
LIG_FHA_2	848	854	PF00498	0.639
LIG_Integrin_RGD_1	464	466	PF01839	0.645
LIG_LIR_Apic_2	430	436	PF02991	0.711
LIG_LIR_Gen_1	239	249	PF02991	0.642
LIG_LIR_Gen_1	755	761	PF02991	0.687
LIG_LIR_Gen_1	781	792	PF02991	0.784
LIG_LIR_Nem_3	239	244	PF02991	0.648
LIG_LIR_Nem_3	39	44	PF02991	0.779
LIG_LIR_Nem_3	755	759	PF02991	0.686
LIG_LIR_Nem_3	781	787	PF02991	0.788
LIG_MYND_1	166	170	PF01753	0.726
LIG_MYND_1	659	663	PF01753	0.798
LIG_MYND_1	688	692	PF01753	0.735
LIG_NRBOX	208	214	PF00104	0.660
LIG_NRBOX	576	582	PF00104	0.771
LIG_Pex14_2	14	18	PF04695	0.719
LIG_Pex14_2	792	796	PF04695	0.713
LIG_SH2_CRK	241	245	PF00017	0.644
LIG_SH2_CRK	44	48	PF00017	0.749
LIG_SH2_NCK_1	44	48	PF00017	0.749
LIG_SH2_SRC	377	380	PF00017	0.578
LIG_SH2_STAP1	699	703	PF00017	0.617
LIG_SH2_STAT5	293	296	PF00017	0.626
LIG_SH2_STAT5	44	47	PF00017	0.637
LIG_SH2_STAT5	845	848	PF00017	0.663
LIG_SH3_1	163	169	PF00018	0.623
LIG_SH3_2	692	697	PF14604	0.684
LIG_SH3_3	163	169	PF00018	0.692
LIG_SH3_3	193	199	PF00018	0.685
LIG_SH3_3	325	331	PF00018	0.765
LIG_SH3_3	34	40	PF00018	0.694
LIG_SH3_3	349	355	PF00018	0.778
LIG_SH3_3	402	408	PF00018	0.672
LIG_SH3_3	426	432	PF00018	0.691
LIG_SH3_3	657	663	PF00018	0.739
LIG_SH3_3	678	684	PF00018	0.743
LIG_SH3_3	689	695	PF00018	0.631
LIG_SH3_3	702	708	PF00018	0.666
LIG_SH3_3	86	92	PF00018	0.734
LIG_SUMO_SIM_anti_2	286	291	PF11976	0.603
LIG_SUMO_SIM_anti_2	576	583	PF11976	0.771
LIG_SUMO_SIM_anti_2	86	91	PF11976	0.738
LIG_SUMO_SIM_par_1	732	738	PF11976	0.715
LIG_SxIP_EBH_1	661	670	PF03271	0.744
LIG_TRFH_1	18	22	PF08558	0.708
LIG_WRC_WIRS_1	650	655	PF05994	0.601
LIG_WW_3	694	698	PF00397	0.699
MOD_CDC14_SPxK_1	178	181	PF00782	0.782
MOD_CDC14_SPxK_1	195	198	PF00782	0.555
MOD_CDC14_SPxK_1	21	24	PF00782	0.704
MOD_CDC14_SPxK_1	35	38	PF00782	0.574
MOD_CDC14_SPxK_1	694	697	PF00782	0.678
MOD_CDC14_SPxK_1	79	82	PF00782	0.721
MOD_CDC14_SPxK_1	803	806	PF00782	0.823
MOD_CDK_SPxK_1	175	181	PF00069	0.788
MOD_CDK_SPxK_1	18	24	PF00069	0.710
MOD_CDK_SPxK_1	192	198	PF00069	0.557
MOD_CDK_SPxK_1	32	38	PF00069	0.580
MOD_CDK_SPxK_1	691	697	PF00069	0.686
MOD_CDK_SPxK_1	76	82	PF00069	0.725
MOD_CDK_SPxK_1	800	806	PF00069	0.818
MOD_CDK_SPxxK_3	18	25	PF00069	0.767
MOD_CDK_SPxxK_3	480	487	PF00069	0.725
MOD_CDK_SPxxK_3	800	807	PF00069	0.709
MOD_CK1_1	315	321	PF00069	0.741
MOD_CK1_1	351	357	PF00069	0.704
MOD_CK1_1	359	365	PF00069	0.726
MOD_CK1_1	503	509	PF00069	0.775
MOD_CK1_1	532	538	PF00069	0.767
MOD_CK1_1	56	62	PF00069	0.754
MOD_CK1_1	583	589	PF00069	0.756
MOD_CK1_1	602	608	PF00069	0.568
MOD_CK1_1	632	638	PF00069	0.815
MOD_CK1_1	651	657	PF00069	0.772
MOD_CK1_1	664	670	PF00069	0.638
MOD_CK1_1	686	692	PF00069	0.787
MOD_CK1_1	716	722	PF00069	0.761
MOD_CK1_1	799	805	PF00069	0.767
MOD_CK1_1	820	826	PF00069	0.750
MOD_CK2_1	313	319	PF00069	0.730
MOD_CK2_1	573	579	PF00069	0.763
MOD_CK2_1	622	628	PF00069	0.841
MOD_CK2_1	847	853	PF00069	0.644
MOD_GlcNHglycan	117	120	PF01048	0.806
MOD_GlcNHglycan	121	125	PF01048	0.773
MOD_GlcNHglycan	251	254	PF01048	0.467
MOD_GlcNHglycan	263	267	PF01048	0.561
MOD_GlcNHglycan	268	271	PF01048	0.581
MOD_GlcNHglycan	336	339	PF01048	0.712
MOD_GlcNHglycan	358	361	PF01048	0.763
MOD_GlcNHglycan	378	382	PF01048	0.790
MOD_GlcNHglycan	439	443	PF01048	0.631
MOD_GlcNHglycan	455	458	PF01048	0.714
MOD_GlcNHglycan	495	498	PF01048	0.786
MOD_GlcNHglycan	512	515	PF01048	0.637
MOD_GlcNHglycan	556	559	PF01048	0.699
MOD_GlcNHglycan	571	574	PF01048	0.700
MOD_GlcNHglycan	612	615	PF01048	0.650
MOD_GlcNHglycan	654	657	PF01048	0.803
MOD_GlcNHglycan	672	675	PF01048	0.548
MOD_GlcNHglycan	715	718	PF01048	0.835
MOD_GlcNHglycan	74	77	PF01048	0.755
MOD_GlcNHglycan	861	864	PF01048	0.765
MOD_GSK3_1	175	182	PF00069	0.733
MOD_GSK3_1	183	190	PF00069	0.603
MOD_GSK3_1	262	269	PF00069	0.532
MOD_GSK3_1	305	312	PF00069	0.744
MOD_GSK3_1	32	39	PF00069	0.790
MOD_GSK3_1	323	330	PF00069	0.728
MOD_GSK3_1	347	354	PF00069	0.618
MOD_GSK3_1	365	372	PF00069	0.748
MOD_GSK3_1	377	384	PF00069	0.572
MOD_GSK3_1	42	49	PF00069	0.672
MOD_GSK3_1	434	441	PF00069	0.644
MOD_GSK3_1	444	451	PF00069	0.595
MOD_GSK3_1	510	517	PF00069	0.669
MOD_GSK3_1	522	529	PF00069	0.726
MOD_GSK3_1	547	554	PF00069	0.797
MOD_GSK3_1	569	576	PF00069	0.770
MOD_GSK3_1	580	587	PF00069	0.629
MOD_GSK3_1	598	605	PF00069	0.545
MOD_GSK3_1	627	634	PF00069	0.830
MOD_GSK3_1	648	655	PF00069	0.794
MOD_GSK3_1	659	666	PF00069	0.629
MOD_GSK3_1	679	686	PF00069	0.583
MOD_GSK3_1	699	706	PF00069	0.558
MOD_GSK3_1	72	79	PF00069	0.762
MOD_GSK3_1	792	799	PF00069	0.733
MOD_GSK3_1	817	824	PF00069	0.753
MOD_GSK3_1	843	850	PF00069	0.652
MOD_LATS_1	763	769	PF00433	0.831
MOD_LATS_1	815	821	PF00433	0.734
MOD_NEK2_1	249	254	PF00069	0.467
MOD_NEK2_1	262	267	PF00069	0.461
MOD_NEK2_1	334	339	PF00069	0.700
MOD_NEK2_1	369	374	PF00069	0.750
MOD_NEK2_1	526	531	PF00069	0.687
MOD_NEK2_1	598	603	PF00069	0.733
MOD_NEK2_1	739	744	PF00069	0.712
MOD_NEK2_1	759	764	PF00069	0.775
MOD_NEK2_1	786	791	PF00069	0.643
MOD_NEK2_1	792	797	PF00069	0.611
MOD_NEK2_2	522	527	PF00069	0.697
MOD_PIKK_1	313	319	PF00454	0.804
MOD_PIKK_1	42	48	PF00454	0.615
MOD_PIKK_1	847	853	PF00454	0.644
MOD_PK_1	765	771	PF00069	0.793
MOD_PKA_2	234	240	PF00069	0.540
MOD_PKA_2	283	289	PF00069	0.629
MOD_PKA_2	305	311	PF00069	0.664
MOD_PKA_2	365	371	PF00069	0.688
MOD_PKA_2	453	459	PF00069	0.610
MOD_PKA_2	493	499	PF00069	0.758
MOD_PKA_2	500	506	PF00069	0.778
MOD_PKA_2	583	589	PF00069	0.799
MOD_PKA_2	669	675	PF00069	0.813
MOD_PKA_2	83	89	PF00069	0.617
MOD_PKB_1	582	590	PF00069	0.792
MOD_Plk_1	151	157	PF00069	0.602
MOD_Plk_1	187	193	PF00069	0.615
MOD_Plk_1	599	605	PF00069	0.639
MOD_Plk_1	622	628	PF00069	0.675
MOD_Plk_2-3	151	157	PF00069	0.602
MOD_Plk_2-3	434	440	PF00069	0.713
MOD_Plk_2-3	830	836	PF00069	0.808
MOD_Plk_4	340	346	PF00069	0.674
MOD_Plk_4	503	509	PF00069	0.617
MOD_Plk_4	533	539	PF00069	0.697
MOD_Plk_4	573	579	PF00069	0.748
MOD_Plk_4	686	692	PF00069	0.669
MOD_Plk_4	85	91	PF00069	0.737
MOD_ProDKin_1	170	176	PF00069	0.777
MOD_ProDKin_1	18	24	PF00069	0.765
MOD_ProDKin_1	181	187	PF00069	0.627
MOD_ProDKin_1	192	198	PF00069	0.589
MOD_ProDKin_1	32	38	PF00069	0.596
MOD_ProDKin_1	323	329	PF00069	0.809
MOD_ProDKin_1	348	354	PF00069	0.778
MOD_ProDKin_1	480	486	PF00069	0.763
MOD_ProDKin_1	501	507	PF00069	0.687
MOD_ProDKin_1	527	533	PF00069	0.761
MOD_ProDKin_1	607	613	PF00069	0.659
MOD_ProDKin_1	659	665	PF00069	0.786
MOD_ProDKin_1	691	697	PF00069	0.737
MOD_ProDKin_1	704	710	PF00069	0.601
MOD_ProDKin_1	741	747	PF00069	0.763
MOD_ProDKin_1	76	82	PF00069	0.725
MOD_ProDKin_1	800	806	PF00069	0.818
MOD_ProDKin_1	91	97	PF00069	0.790
MOD_SUMO_for_1	270	273	PF00179	0.652
MOD_SUMO_for_1	675	678	PF00179	0.698
TRG_DiLeu_BaLyEn_6	171	176	PF01217	0.750
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.697
TRG_ENDOCYTIC_2	241	244	PF00928	0.642
TRG_ER_diArg_1	138	141	PF00400	0.738
TRG_ER_diArg_1	161	164	PF00400	0.624
TRG_ER_diArg_1	203	205	PF00400	0.736
TRG_ER_diArg_1	283	285	PF00400	0.528
TRG_ER_diArg_1	470	473	PF00400	0.621
TRG_ER_diArg_1	581	584	PF00400	0.779
TRG_ER_diArg_1	806	808	PF00400	0.736
TRG_Pf-PMV_PEXEL_1	153	158	PF00026	0.617
TRG_Pf-PMV_PEXEL_1	214	219	PF00026	0.626
TRG_Pf-PMV_PEXEL_1	806	810	PF00026	0.829

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HFW0	Leishmania braziliensis	56%	100%
A4I2Z2	Leishmania infantum	99%	100%
E9ADG4	Leishmania major	86%	100%
E9AZ88	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	99%