LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8ID69_LEIDO
TriTrypDb:
LdBPK_250310.1 , LdCL_250008200 , LDHU3_25.0380
Length:
90

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID69
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID69

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 46 48 PF00675 0.700
CLV_NRD_NRD_1 87 89 PF00675 0.501
CLV_PCSK_FUR_1 85 89 PF00082 0.495
CLV_PCSK_KEX2_1 46 48 PF00082 0.700
CLV_PCSK_KEX2_1 87 89 PF00082 0.450
DEG_APCC_DBOX_1 45 53 PF00400 0.528
DOC_MAPK_gen_1 46 53 PF00069 0.498
DOC_MAPK_MEF2A_6 34 41 PF00069 0.524
DOC_MAPK_MEF2A_6 46 55 PF00069 0.527
DOC_MAPK_NFAT4_5 34 42 PF00069 0.458
DOC_USP7_UBL2_3 25 29 PF12436 0.553
DOC_WW_Pin1_4 24 29 PF00397 0.512
DOC_WW_Pin1_4 39 44 PF00397 0.557
LIG_BIR_II_1 1 5 PF00653 0.642
LIG_BRCT_BRCA1_1 62 66 PF00533 0.332
LIG_FHA_2 40 46 PF00498 0.516
LIG_GBD_Chelix_1 53 61 PF00786 0.570
LIG_SH2_CRK 80 84 PF00017 0.664
LIG_Sin3_3 54 61 PF02671 0.370
LIG_TYR_ITIM 78 83 PF00017 0.571
MOD_CDK_SPK_2 24 29 PF00069 0.553
MOD_CDK_SPxxK_3 39 46 PF00069 0.551
MOD_CK1_1 23 29 PF00069 0.582
MOD_CK2_1 24 30 PF00069 0.515
MOD_CK2_1 39 45 PF00069 0.524
MOD_GlcNHglycan 1 4 PF01048 0.843
MOD_GlcNHglycan 22 25 PF01048 0.823
MOD_GlcNHglycan 30 34 PF01048 0.747
MOD_GlcNHglycan 74 77 PF01048 0.529
MOD_GSK3_1 16 23 PF00069 0.585
MOD_GSK3_1 35 42 PF00069 0.370
MOD_NEK2_1 37 42 PF00069 0.416
MOD_ProDKin_1 24 30 PF00069 0.511
MOD_ProDKin_1 39 45 PF00069 0.553
TRG_DiLeu_BaEn_1 45 50 PF01217 0.527
TRG_ENDOCYTIC_2 80 83 PF00928 0.726
TRG_ER_diArg_1 85 88 PF00400 0.694

Homologs

Protein Taxonomy Sequence identity Coverage
A4I173 Leishmania infantum 99% 100%
E9AIR4 Leishmania braziliensis 62% 100%
E9AXA7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
Q4QA65 Leishmania major 88% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS