LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8ID56_LEIDO
TriTrypDb:
LdBPK_281740.1 , LdCL_280022300 , LDHU3_28.2270
Length:
332

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID56
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID56

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 183 185 PF00675 0.604
CLV_NRD_NRD_1 312 314 PF00675 0.684
CLV_NRD_NRD_1 81 83 PF00675 0.606
CLV_PCSK_KEX2_1 183 185 PF00082 0.601
CLV_PCSK_KEX2_1 312 314 PF00082 0.684
CLV_PCSK_KEX2_1 81 83 PF00082 0.606
CLV_PCSK_PC7_1 179 185 PF00082 0.567
CLV_PCSK_SKI1_1 185 189 PF00082 0.664
CLV_PCSK_SKI1_1 313 317 PF00082 0.614
CLV_PCSK_SKI1_1 92 96 PF00082 0.640
DEG_Nend_UBRbox_3 1 3 PF02207 0.721
DEG_SPOP_SBC_1 70 74 PF00917 0.684
DOC_CKS1_1 28 33 PF01111 0.686
DOC_CKS1_1 35 40 PF01111 0.608
DOC_MAPK_gen_1 183 192 PF00069 0.646
DOC_MAPK_MEF2A_6 183 190 PF00069 0.600
DOC_MAPK_MEF2A_6 88 95 PF00069 0.609
DOC_MAPK_NFAT4_5 183 191 PF00069 0.607
DOC_PP1_RVXF_1 126 133 PF00149 0.611
DOC_PP4_FxxP_1 132 135 PF00568 0.628
DOC_USP7_MATH_1 226 230 PF00917 0.740
DOC_USP7_MATH_1 287 291 PF00917 0.579
DOC_USP7_MATH_1 311 315 PF00917 0.671
DOC_USP7_MATH_1 319 323 PF00917 0.628
DOC_USP7_MATH_1 71 75 PF00917 0.753
DOC_USP7_MATH_2 296 302 PF00917 0.620
DOC_USP7_UBL2_3 8 12 PF12436 0.676
DOC_USP7_UBL2_3 88 92 PF12436 0.611
DOC_WW_Pin1_4 10 15 PF00397 0.749
DOC_WW_Pin1_4 206 211 PF00397 0.783
DOC_WW_Pin1_4 21 26 PF00397 0.618
DOC_WW_Pin1_4 215 220 PF00397 0.671
DOC_WW_Pin1_4 250 255 PF00397 0.690
DOC_WW_Pin1_4 27 32 PF00397 0.534
DOC_WW_Pin1_4 299 304 PF00397 0.697
DOC_WW_Pin1_4 34 39 PF00397 0.562
DOC_WW_Pin1_4 99 104 PF00397 0.740
LIG_14-3-3_CanoR_1 151 159 PF00244 0.583
LIG_14-3-3_CanoR_1 276 284 PF00244 0.713
LIG_14-3-3_CanoR_1 312 319 PF00244 0.704
LIG_BRCT_BRCA1_1 269 273 PF00533 0.695
LIG_EVH1_2 293 297 PF00568 0.672
LIG_FHA_1 153 159 PF00498 0.554
LIG_FHA_1 53 59 PF00498 0.680
LIG_FHA_2 100 106 PF00498 0.748
LIG_FHA_2 35 41 PF00498 0.688
LIG_PAM2_1 250 262 PF00658 0.715
LIG_RPA_C_Fungi 174 186 PF08784 0.598
LIG_SH2_CRK 35 39 PF00017 0.754
LIG_SH2_CRK 68 72 PF00017 0.738
LIG_SH2_SRC 68 71 PF00017 0.697
LIG_SH2_STAT5 57 60 PF00017 0.721
LIG_SH3_2 31 36 PF14604 0.656
LIG_SH3_3 207 213 PF00018 0.781
LIG_SH3_3 216 222 PF00018 0.673
LIG_SH3_3 28 34 PF00018 0.662
LIG_SH3_3 290 296 PF00018 0.781
LIG_SH3_4 88 95 PF00018 0.609
LIG_SUMO_SIM_anti_2 157 163 PF11976 0.543
LIG_TRAF2_1 102 105 PF00917 0.767
LIG_WRC_WIRS_1 279 284 PF05994 0.505
MOD_CDK_SPK_2 34 39 PF00069 0.674
MOD_CK1_1 21 27 PF00069 0.732
MOD_CK1_1 217 223 PF00069 0.851
MOD_CK1_1 246 252 PF00069 0.574
MOD_CK1_1 321 327 PF00069 0.584
MOD_CK2_1 151 157 PF00069 0.588
MOD_CK2_1 164 170 PF00069 0.590
MOD_CK2_1 99 105 PF00069 0.742
MOD_GlcNHglycan 145 148 PF01048 0.571
MOD_GlcNHglycan 166 169 PF01048 0.607
MOD_GlcNHglycan 172 176 PF01048 0.510
MOD_GlcNHglycan 20 23 PF01048 0.726
MOD_GlcNHglycan 228 231 PF01048 0.766
MOD_GlcNHglycan 246 249 PF01048 0.525
MOD_GlcNHglycan 285 288 PF01048 0.576
MOD_GlcNHglycan 313 316 PF01048 0.686
MOD_GlcNHglycan 321 324 PF01048 0.689
MOD_GSK3_1 240 247 PF00069 0.688
MOD_GSK3_1 278 285 PF00069 0.682
MOD_GSK3_1 319 326 PF00069 0.756
MOD_GSK3_1 48 55 PF00069 0.695
MOD_GSK3_1 95 102 PF00069 0.698
MOD_LATS_1 111 117 PF00433 0.678
MOD_N-GLC_1 143 148 PF02516 0.653
MOD_N-GLC_1 282 287 PF02516 0.643
MOD_NEK2_1 164 169 PF00069 0.634
MOD_NEK2_1 282 287 PF00069 0.703
MOD_NEK2_1 48 53 PF00069 0.751
MOD_NEK2_1 94 99 PF00069 0.711
MOD_PIKK_1 106 112 PF00454 0.690
MOD_PIKK_1 326 332 PF00454 0.663
MOD_PIKK_1 71 77 PF00454 0.762
MOD_PK_1 113 119 PF00069 0.734
MOD_PKA_1 81 87 PF00069 0.587
MOD_PKA_2 18 24 PF00069 0.764
MOD_PKA_2 311 317 PF00069 0.710
MOD_PKA_2 326 332 PF00069 0.526
MOD_PKA_2 81 87 PF00069 0.698
MOD_Plk_1 171 177 PF00069 0.601
MOD_Plk_1 53 59 PF00069 0.680
MOD_Plk_4 113 119 PF00069 0.734
MOD_Plk_4 240 246 PF00069 0.694
MOD_Plk_4 53 59 PF00069 0.718
MOD_ProDKin_1 10 16 PF00069 0.751
MOD_ProDKin_1 206 212 PF00069 0.780
MOD_ProDKin_1 21 27 PF00069 0.618
MOD_ProDKin_1 215 221 PF00069 0.670
MOD_ProDKin_1 250 256 PF00069 0.694
MOD_ProDKin_1 299 305 PF00069 0.698
MOD_ProDKin_1 34 40 PF00069 0.558
MOD_ProDKin_1 99 105 PF00069 0.742
TRG_DiLeu_BaEn_1 157 162 PF01217 0.568
TRG_DiLeu_BaLyEn_6 125 130 PF01217 0.603
TRG_DiLeu_LyEn_5 44 49 PF01217 0.716
TRG_NES_CRM1_1 157 170 PF08389 0.582
TRG_Pf-PMV_PEXEL_1 184 189 PF00026 0.680

Homologs

Protein Taxonomy Sequence identity Coverage
A4HGL4 Leishmania braziliensis 74% 99%
A4I3P0 Leishmania infantum 99% 100%
E9AZY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4Q8A4 Leishmania major 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS