LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8ID47_LEIDO
TriTrypDb:
LdBPK_250280.1 * , LdCL_250007900 , LDHU3_25.0340
Length:
691

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID47
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID47

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 28 32 PF00656 0.681
CLV_C14_Caspase3-7 444 448 PF00656 0.638
CLV_C14_Caspase3-7 551 555 PF00656 0.629
CLV_C14_Caspase3-7 68 72 PF00656 0.579
CLV_NRD_NRD_1 163 165 PF00675 0.663
CLV_NRD_NRD_1 17 19 PF00675 0.786
CLV_NRD_NRD_1 275 277 PF00675 0.851
CLV_NRD_NRD_1 285 287 PF00675 0.667
CLV_NRD_NRD_1 491 493 PF00675 0.518
CLV_NRD_NRD_1 533 535 PF00675 0.678
CLV_NRD_NRD_1 544 546 PF00675 0.716
CLV_PCSK_FUR_1 15 19 PF00082 0.671
CLV_PCSK_FUR_1 342 346 PF00082 0.518
CLV_PCSK_KEX2_1 15 17 PF00082 0.782
CLV_PCSK_KEX2_1 162 164 PF00082 0.665
CLV_PCSK_KEX2_1 275 277 PF00082 0.851
CLV_PCSK_KEX2_1 285 287 PF00082 0.667
CLV_PCSK_KEX2_1 344 346 PF00082 0.674
CLV_PCSK_KEX2_1 491 493 PF00082 0.582
CLV_PCSK_KEX2_1 533 535 PF00082 0.678
CLV_PCSK_KEX2_1 544 546 PF00082 0.716
CLV_PCSK_KEX2_1 92 94 PF00082 0.539
CLV_PCSK_PC1ET2_1 344 346 PF00082 0.674
CLV_PCSK_PC1ET2_1 92 94 PF00082 0.573
CLV_PCSK_PC7_1 281 287 PF00082 0.829
CLV_PCSK_PC7_1 340 346 PF00082 0.597
CLV_PCSK_PC7_1 88 94 PF00082 0.573
CLV_PCSK_SKI1_1 286 290 PF00082 0.833
CLV_PCSK_SKI1_1 365 369 PF00082 0.635
CLV_PCSK_SKI1_1 391 395 PF00082 0.613
CLV_PCSK_SKI1_1 407 411 PF00082 0.426
DEG_APCC_DBOX_1 147 155 PF00400 0.547
DEG_APCC_DBOX_1 406 414 PF00400 0.607
DEG_APCC_DBOX_1 87 95 PF00400 0.652
DOC_CKS1_1 421 426 PF01111 0.568
DOC_CKS1_1 568 573 PF01111 0.710
DOC_CYCLIN_RxL_1 404 414 PF00134 0.554
DOC_CYCLIN_yCln2_LP_2 421 427 PF00134 0.568
DOC_MAPK_gen_1 285 292 PF00069 0.828
DOC_MAPK_gen_1 352 361 PF00069 0.622
DOC_MAPK_gen_1 396 405 PF00069 0.629
DOC_MAPK_MEF2A_6 203 212 PF00069 0.540
DOC_MAPK_MEF2A_6 285 292 PF00069 0.828
DOC_PP1_RVXF_1 294 300 PF00149 0.610
DOC_PP2B_LxvP_1 596 599 PF13499 0.710
DOC_USP7_MATH_1 130 134 PF00917 0.484
DOC_USP7_MATH_1 253 257 PF00917 0.720
DOC_USP7_MATH_1 266 270 PF00917 0.617
DOC_USP7_MATH_1 280 284 PF00917 0.651
DOC_USP7_MATH_1 305 309 PF00917 0.762
DOC_USP7_MATH_1 416 420 PF00917 0.641
DOC_USP7_MATH_1 443 447 PF00917 0.813
DOC_USP7_MATH_1 507 511 PF00917 0.622
DOC_USP7_MATH_1 627 631 PF00917 0.837
DOC_USP7_MATH_1 637 641 PF00917 0.640
DOC_WW_Pin1_4 17 22 PF00397 0.673
DOC_WW_Pin1_4 257 262 PF00397 0.750
DOC_WW_Pin1_4 269 274 PF00397 0.661
DOC_WW_Pin1_4 276 281 PF00397 0.550
DOC_WW_Pin1_4 300 305 PF00397 0.798
DOC_WW_Pin1_4 314 319 PF00397 0.608
DOC_WW_Pin1_4 420 425 PF00397 0.592
DOC_WW_Pin1_4 567 572 PF00397 0.764
DOC_WW_Pin1_4 683 688 PF00397 0.806
DOC_WW_Pin1_4 9 14 PF00397 0.766
LIG_14-3-3_CanoR_1 247 255 PF00244 0.630
LIG_14-3-3_CanoR_1 275 282 PF00244 0.842
LIG_14-3-3_CanoR_1 285 291 PF00244 0.680
LIG_14-3-3_CanoR_1 296 300 PF00244 0.602
LIG_14-3-3_CanoR_1 352 357 PF00244 0.558
LIG_14-3-3_CanoR_1 365 375 PF00244 0.646
LIG_14-3-3_CanoR_1 548 557 PF00244 0.565
LIG_14-3-3_CanoR_1 86 92 PF00244 0.657
LIG_BIR_II_1 1 5 PF00653 0.693
LIG_BRCT_BRCA1_1 255 259 PF00533 0.812
LIG_BRCT_BRCA1_1 3 7 PF00533 0.601
LIG_CaM_IQ_9 78 94 PF13499 0.594
LIG_Clathr_ClatBox_1 383 387 PF01394 0.698
LIG_FHA_1 115 121 PF00498 0.657
LIG_FHA_1 133 139 PF00498 0.365
LIG_FHA_1 287 293 PF00498 0.825
LIG_FHA_1 591 597 PF00498 0.755
LIG_FHA_1 602 608 PF00498 0.638
LIG_FHA_1 82 88 PF00498 0.669
LIG_FHA_2 126 132 PF00498 0.623
LIG_FHA_2 353 359 PF00498 0.484
LIG_FHA_2 421 427 PF00498 0.670
LIG_FHA_2 511 517 PF00498 0.663
LIG_FHA_2 549 555 PF00498 0.700
LIG_FHA_2 618 624 PF00498 0.709
LIG_FHA_2 66 72 PF00498 0.581
LIG_FHA_2 684 690 PF00498 0.809
LIG_GBD_Chelix_1 405 413 PF00786 0.689
LIG_LIR_Gen_1 216 224 PF02991 0.652
LIG_LIR_Nem_3 216 220 PF02991 0.635
LIG_LIR_Nem_3 298 302 PF02991 0.700
LIG_LIR_Nem_3 686 691 PF02991 0.800
LIG_PCNA_yPIPBox_3 365 379 PF02747 0.716
LIG_PCNA_yPIPBox_3 515 524 PF02747 0.714
LIG_Rb_LxCxE_1 471 490 PF01857 0.622
LIG_SH2_CRK 302 306 PF00017 0.751
LIG_SH2_NCK_1 302 306 PF00017 0.790
LIG_SH2_STAT3 74 77 PF00017 0.694
LIG_SH2_STAT5 42 45 PF00017 0.569
LIG_SH2_STAT5 98 101 PF00017 0.631
LIG_SH3_2 598 603 PF14604 0.726
LIG_SH3_3 437 443 PF00018 0.659
LIG_SH3_3 451 457 PF00018 0.637
LIG_SH3_3 595 601 PF00018 0.787
LIG_SH3_5 687 691 PF00018 0.649
LIG_Sin3_3 183 190 PF02671 0.454
LIG_SUMO_SIM_anti_2 205 211 PF11976 0.478
LIG_SUMO_SIM_anti_2 382 387 PF11976 0.687
LIG_SUMO_SIM_anti_2 400 407 PF11976 0.406
LIG_SUMO_SIM_par_1 287 294 PF11976 0.610
LIG_SUMO_SIM_par_1 382 387 PF11976 0.701
LIG_TRAF2_1 513 516 PF00917 0.733
LIG_WW_3 12 16 PF00397 0.768
MOD_CDC14_SPxK_1 260 263 PF00782 0.585
MOD_CDC14_SPxK_1 272 275 PF00782 0.639
MOD_CDK_SPK_2 276 281 PF00069 0.845
MOD_CDK_SPK_2 314 319 PF00069 0.632
MOD_CDK_SPxK_1 257 263 PF00069 0.617
MOD_CDK_SPxK_1 269 275 PF00069 0.741
MOD_CDK_SPxK_1 9 15 PF00069 0.672
MOD_CDK_SPxxK_3 269 276 PF00069 0.766
MOD_CDK_SPxxK_3 9 16 PF00069 0.771
MOD_CK1_1 20 26 PF00069 0.582
MOD_CK1_1 265 271 PF00069 0.735
MOD_CK1_1 291 297 PF00069 0.646
MOD_CK1_1 482 488 PF00069 0.506
MOD_CK1_1 510 516 PF00069 0.528
MOD_CK1_1 588 594 PF00069 0.640
MOD_CK1_1 6 12 PF00069 0.763
MOD_CK1_1 676 682 PF00069 0.709
MOD_CK1_1 72 78 PF00069 0.688
MOD_CK2_1 305 311 PF00069 0.825
MOD_CK2_1 335 341 PF00069 0.602
MOD_CK2_1 352 358 PF00069 0.580
MOD_CK2_1 420 426 PF00069 0.662
MOD_CK2_1 510 516 PF00069 0.658
MOD_GlcNHglycan 1 4 PF01048 0.711
MOD_GlcNHglycan 128 131 PF01048 0.596
MOD_GlcNHglycan 199 202 PF01048 0.598
MOD_GlcNHglycan 233 236 PF01048 0.690
MOD_GlcNHglycan 255 258 PF01048 0.805
MOD_GlcNHglycan 307 310 PF01048 0.832
MOD_GlcNHglycan 311 314 PF01048 0.817
MOD_GlcNHglycan 337 340 PF01048 0.556
MOD_GlcNHglycan 418 421 PF01048 0.738
MOD_GlcNHglycan 481 484 PF01048 0.668
MOD_GlcNHglycan 587 590 PF01048 0.740
MOD_GlcNHglycan 623 627 PF01048 0.750
MOD_GlcNHglycan 71 74 PF01048 0.710
MOD_GlcNHglycan 8 11 PF01048 0.674
MOD_GSK3_1 1 8 PF00069 0.644
MOD_GSK3_1 126 133 PF00069 0.512
MOD_GSK3_1 169 176 PF00069 0.512
MOD_GSK3_1 253 260 PF00069 0.768
MOD_GSK3_1 262 269 PF00069 0.659
MOD_GSK3_1 276 283 PF00069 0.608
MOD_GSK3_1 284 291 PF00069 0.699
MOD_GSK3_1 305 312 PF00069 0.686
MOD_GSK3_1 416 423 PF00069 0.686
MOD_GSK3_1 443 450 PF00069 0.747
MOD_GSK3_1 455 462 PF00069 0.671
MOD_GSK3_1 584 591 PF00069 0.621
MOD_GSK3_1 618 625 PF00069 0.739
MOD_GSK3_1 65 72 PF00069 0.670
MOD_GSK3_1 77 84 PF00069 0.630
MOD_N-GLC_1 253 258 PF02516 0.710
MOD_N-GLC_1 69 74 PF02516 0.715
MOD_NEK2_1 1 6 PF00069 0.559
MOD_NEK2_1 132 137 PF00069 0.490
MOD_NEK2_1 479 484 PF00069 0.526
MOD_NEK2_1 87 92 PF00069 0.654
MOD_NEK2_2 637 642 PF00069 0.593
MOD_PIKK_1 280 286 PF00454 0.829
MOD_PIKK_1 510 516 PF00454 0.658
MOD_PKA_2 231 237 PF00069 0.665
MOD_PKA_2 274 280 PF00069 0.847
MOD_PKA_2 284 290 PF00069 0.681
MOD_PKA_2 295 301 PF00069 0.601
MOD_PKA_2 416 422 PF00069 0.526
MOD_PKA_2 547 553 PF00069 0.701
MOD_PKA_2 584 590 PF00069 0.716
MOD_PKA_2 616 622 PF00069 0.709
MOD_PKA_2 63 69 PF00069 0.801
MOD_PKA_2 87 93 PF00069 0.655
MOD_Plk_1 130 136 PF00069 0.663
MOD_Plk_1 363 369 PF00069 0.670
MOD_Plk_1 430 436 PF00069 0.682
MOD_Plk_1 564 570 PF00069 0.752
MOD_Plk_1 57 63 PF00069 0.721
MOD_Plk_4 20 26 PF00069 0.759
MOD_Plk_4 517 523 PF00069 0.496
MOD_Plk_4 538 544 PF00069 0.632
MOD_Plk_4 57 63 PF00069 0.688
MOD_ProDKin_1 17 23 PF00069 0.672
MOD_ProDKin_1 257 263 PF00069 0.755
MOD_ProDKin_1 269 275 PF00069 0.664
MOD_ProDKin_1 276 282 PF00069 0.546
MOD_ProDKin_1 300 306 PF00069 0.797
MOD_ProDKin_1 314 320 PF00069 0.605
MOD_ProDKin_1 420 426 PF00069 0.596
MOD_ProDKin_1 567 573 PF00069 0.769
MOD_ProDKin_1 683 689 PF00069 0.804
MOD_ProDKin_1 9 15 PF00069 0.769
TRG_DiLeu_BaEn_1 122 127 PF01217 0.667
TRG_DiLeu_BaEn_1 205 210 PF01217 0.485
TRG_DiLeu_BaEn_1 374 379 PF01217 0.703
TRG_ER_diArg_1 14 17 PF00400 0.777
TRG_ER_diArg_1 161 164 PF00400 0.666
TRG_ER_diArg_1 543 545 PF00400 0.725
TRG_ER_diArg_1 608 611 PF00400 0.677
TRG_NES_CRM1_1 374 387 PF08389 0.555
TRG_Pf-PMV_PEXEL_1 136 141 PF00026 0.548
TRG_Pf-PMV_PEXEL_1 354 358 PF00026 0.643
TRG_Pf-PMV_PEXEL_1 365 370 PF00026 0.601
TRG_Pf-PMV_PEXEL_1 407 411 PF00026 0.671
TRG_Pf-PMV_PEXEL_1 524 528 PF00026 0.625

Homologs

Protein Taxonomy Sequence identity Coverage
A4HDX5 Leishmania braziliensis 60% 99%
A4I170 Leishmania infantum 99% 100%
E9AXA4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4QA68 Leishmania major 83% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS