Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ID42_LEIDO

TriTrypDb:

LdBPK_270140.1 , LdCL_270006300 , LDHU3_27.0180

Length:

213

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID42

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID42

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	135	137	PF00675	0.727
CLV_NRD_NRD_1	75	77	PF00675	0.614
CLV_PCSK_KEX2_1	107	109	PF00082	0.635
CLV_PCSK_KEX2_1	75	77	PF00082	0.556
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.623
CLV_PCSK_PC7_1	71	77	PF00082	0.546
CLV_PCSK_SKI1_1	144	148	PF00082	0.676
CLV_PCSK_SKI1_1	182	186	PF00082	0.690
CLV_PCSK_SKI1_1	88	92	PF00082	0.745
DEG_Nend_Nbox_1	1	3	PF02207	0.520
DOC_CKS1_1	147	152	PF01111	0.619
DOC_USP7_MATH_1	22	26	PF00917	0.621
DOC_USP7_MATH_1	54	58	PF00917	0.600
DOC_USP7_MATH_1	81	85	PF00917	0.524
DOC_WW_Pin1_4	12	17	PF00397	0.613
DOC_WW_Pin1_4	121	126	PF00397	0.740
DOC_WW_Pin1_4	146	151	PF00397	0.616
LIG_14-3-3_CanoR_1	108	112	PF00244	0.665
LIG_14-3-3_CanoR_1	186	194	PF00244	0.693
LIG_14-3-3_CanoR_1	58	64	PF00244	0.553
LIG_BIR_III_4	114	118	PF00653	0.674
LIG_deltaCOP1_diTrp_1	159	165	PF00928	0.598
LIG_FHA_1	107	113	PF00498	0.633
LIG_FHA_2	154	160	PF00498	0.648
LIG_FHA_2	87	93	PF00498	0.594
LIG_LIR_Nem_3	84	90	PF02991	0.652
LIG_Pex14_1	161	165	PF04695	0.594
LIG_SH2_CRK	87	91	PF00017	0.656
LIG_SH2_STAT5	200	203	PF00017	0.574
LIG_SH2_STAT5	79	82	PF00017	0.696
LIG_SH3_2	152	157	PF14604	0.554
LIG_SH3_3	149	155	PF00018	0.601
LIG_WRC_WIRS_1	162	167	PF05994	0.646
MOD_CDK_SPK_2	146	151	PF00069	0.616
MOD_CK1_1	25	31	PF00069	0.706
MOD_CK1_1	7	13	PF00069	0.603
MOD_CK2_1	153	159	PF00069	0.694
MOD_GlcNHglycan	11	14	PF01048	0.728
MOD_GlcNHglycan	114	118	PF01048	0.668
MOD_GlcNHglycan	24	27	PF01048	0.630
MOD_GSK3_1	161	168	PF00069	0.707
MOD_GSK3_1	178	185	PF00069	0.507
MOD_GSK3_1	59	66	PF00069	0.567
MOD_GSK3_1	77	84	PF00069	0.617
MOD_N-GLC_1	127	132	PF02516	0.573
MOD_NEK2_1	106	111	PF00069	0.671
MOD_NEK2_1	165	170	PF00069	0.763
MOD_PKA_1	107	113	PF00069	0.615
MOD_PKA_2	107	113	PF00069	0.601
MOD_PKA_2	178	184	PF00069	0.585
MOD_PKA_2	207	213	PF00069	0.559
MOD_PKA_2	54	60	PF00069	0.628
MOD_PKA_2	70	76	PF00069	0.611
MOD_Plk_1	47	53	PF00069	0.620
MOD_Plk_4	107	113	PF00069	0.637
MOD_Plk_4	115	121	PF00069	0.575
MOD_Plk_4	25	31	PF00069	0.648
MOD_ProDKin_1	12	18	PF00069	0.616
MOD_ProDKin_1	121	127	PF00069	0.741
MOD_ProDKin_1	146	152	PF00069	0.615
TRG_ENDOCYTIC_2	87	90	PF00928	0.583
TRG_ER_diArg_1	75	77	PF00400	0.542

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJK2	Leptomonas seymouri	39%	89%
A4I362	Leishmania infantum	99%	100%
E9ACZ1	Leishmania major	92%	100%
E9AIS4	Leishmania braziliensis	69%	100%
E9AYR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%