Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8ID28_LEIDO

TriTrypDb:

LdBPK_241480.1 , LdCL_240020000 , LDHU3_24.1790

Length:

913

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID28

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID28

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.639
CLV_C14_Caspase3-7	66	70	PF00656	0.559
CLV_C14_Caspase3-7	758	762	PF00656	0.714
CLV_C14_Caspase3-7	826	830	PF00656	0.593
CLV_MEL_PAP_1	463	469	PF00089	0.649
CLV_NRD_NRD_1	332	334	PF00675	0.654
CLV_NRD_NRD_1	379	381	PF00675	0.709
CLV_NRD_NRD_1	673	675	PF00675	0.819
CLV_NRD_NRD_1	733	735	PF00675	0.761
CLV_NRD_NRD_1	770	772	PF00675	0.590
CLV_NRD_NRD_1	903	905	PF00675	0.677
CLV_NRD_NRD_1	906	908	PF00675	0.703
CLV_PCSK_FUR_1	674	678	PF00082	0.672
CLV_PCSK_FUR_1	768	772	PF00082	0.594
CLV_PCSK_FUR_1	904	908	PF00082	0.670
CLV_PCSK_KEX2_1	672	674	PF00082	0.809
CLV_PCSK_KEX2_1	676	678	PF00082	0.779
CLV_PCSK_KEX2_1	770	772	PF00082	0.590
CLV_PCSK_KEX2_1	883	885	PF00082	0.589
CLV_PCSK_KEX2_1	903	905	PF00082	0.604
CLV_PCSK_KEX2_1	906	908	PF00082	0.703
CLV_PCSK_PC1ET2_1	672	674	PF00082	0.694
CLV_PCSK_PC1ET2_1	676	678	PF00082	0.682
CLV_PCSK_PC1ET2_1	883	885	PF00082	0.565
CLV_PCSK_SKI1_1	423	427	PF00082	0.600
CLV_PCSK_SKI1_1	673	677	PF00082	0.758
CLV_PCSK_SKI1_1	680	684	PF00082	0.697
CLV_PCSK_SKI1_1	720	724	PF00082	0.830
CLV_PCSK_SKI1_1	799	803	PF00082	0.675
DEG_SCF_FBW7_1	204	211	PF00400	0.569
DEG_SCF_FBW7_1	392	398	PF00400	0.593
DEG_SPOP_SBC_1	395	399	PF00917	0.657
DEG_SPOP_SBC_1	542	546	PF00917	0.656
DEG_SPOP_SBC_1	79	83	PF00917	0.620
DOC_ANK_TNKS_1	185	192	PF00023	0.665
DOC_CKS1_1	392	397	PF01111	0.591
DOC_CYCLIN_yCln2_LP_2	691	697	PF00134	0.562
DOC_MAPK_gen_1	380	386	PF00069	0.703
DOC_MAPK_gen_1	655	663	PF00069	0.621
DOC_MAPK_gen_1	883	889	PF00069	0.560
DOC_MAPK_MEF2A_6	54	63	PF00069	0.544
DOC_PP2B_LxvP_1	382	385	PF13499	0.695
DOC_PP2B_LxvP_1	480	483	PF13499	0.681
DOC_PP4_FxxP_1	817	820	PF00568	0.654
DOC_USP7_MATH_1	202	206	PF00917	0.663
DOC_USP7_MATH_1	210	214	PF00917	0.677
DOC_USP7_MATH_1	267	271	PF00917	0.625
DOC_USP7_MATH_1	275	279	PF00917	0.613
DOC_USP7_MATH_1	336	340	PF00917	0.710
DOC_USP7_MATH_1	396	400	PF00917	0.722
DOC_USP7_MATH_1	404	408	PF00917	0.636
DOC_USP7_MATH_1	415	419	PF00917	0.529
DOC_USP7_MATH_1	448	452	PF00917	0.635
DOC_USP7_MATH_1	505	509	PF00917	0.693
DOC_USP7_MATH_1	52	56	PF00917	0.589
DOC_USP7_MATH_1	521	525	PF00917	0.578
DOC_USP7_MATH_1	538	542	PF00917	0.588
DOC_USP7_MATH_1	583	587	PF00917	0.698
DOC_USP7_MATH_1	588	592	PF00917	0.673
DOC_USP7_MATH_1	632	636	PF00917	0.787
DOC_USP7_MATH_1	79	83	PF00917	0.611
DOC_USP7_MATH_1	791	795	PF00917	0.679
DOC_USP7_MATH_1	854	858	PF00917	0.613
DOC_USP7_MATH_1	879	883	PF00917	0.651
DOC_USP7_MATH_1	98	102	PF00917	0.586
DOC_USP7_UBL2_3	672	676	PF12436	0.681
DOC_WW_Pin1_4	164	169	PF00397	0.722
DOC_WW_Pin1_4	204	209	PF00397	0.689
DOC_WW_Pin1_4	236	241	PF00397	0.641
DOC_WW_Pin1_4	279	284	PF00397	0.651
DOC_WW_Pin1_4	325	330	PF00397	0.716
DOC_WW_Pin1_4	371	376	PF00397	0.602
DOC_WW_Pin1_4	391	396	PF00397	0.608
DOC_WW_Pin1_4	423	428	PF00397	0.650
DOC_WW_Pin1_4	450	455	PF00397	0.664
DOC_WW_Pin1_4	495	500	PF00397	0.686
DOC_WW_Pin1_4	531	536	PF00397	0.672
DOC_WW_Pin1_4	584	589	PF00397	0.680
DOC_WW_Pin1_4	620	625	PF00397	0.720
DOC_WW_Pin1_4	637	642	PF00397	0.682
DOC_WW_Pin1_4	68	73	PF00397	0.543
DOC_WW_Pin1_4	94	99	PF00397	0.681
LIG_14-3-3_CanoR_1	186	190	PF00244	0.713
LIG_14-3-3_CanoR_1	266	276	PF00244	0.644
LIG_14-3-3_CanoR_1	320	324	PF00244	0.642
LIG_14-3-3_CanoR_1	340	350	PF00244	0.552
LIG_14-3-3_CanoR_1	539	543	PF00244	0.587
LIG_14-3-3_CanoR_1	54	61	PF00244	0.573
LIG_14-3-3_CanoR_1	584	588	PF00244	0.751
LIG_14-3-3_CanoR_1	78	88	PF00244	0.593
LIG_14-3-3_CanoR_1	815	820	PF00244	0.615
LIG_14-3-3_CanoR_1	870	876	PF00244	0.609
LIG_14-3-3_CanoR_1	884	890	PF00244	0.612
LIG_14-3-3_CanoR_1	94	98	PF00244	0.594
LIG_APCC_ABBA_1	661	666	PF00400	0.695
LIG_BIR_II_1	1	5	PF00653	0.687
LIG_BIR_III_2	294	298	PF00653	0.698
LIG_BIR_III_2	69	73	PF00653	0.544
LIG_BRCT_BRCA1_1	434	438	PF00533	0.663
LIG_BRCT_BRCA1_1	545	549	PF00533	0.622
LIG_DLG_GKlike_1	827	835	PF00625	0.624
LIG_eIF4E_1	811	817	PF01652	0.663
LIG_FHA_1	107	113	PF00498	0.556
LIG_FHA_1	218	224	PF00498	0.697
LIG_FHA_1	249	255	PF00498	0.549
LIG_FHA_1	291	297	PF00498	0.686
LIG_FHA_1	372	378	PF00498	0.688
LIG_FHA_1	567	573	PF00498	0.716
LIG_FHA_1	606	612	PF00498	0.621
LIG_FHA_1	638	644	PF00498	0.702
LIG_FHA_2	240	246	PF00498	0.625
LIG_FHA_2	386	392	PF00498	0.606
LIG_FHA_2	424	430	PF00498	0.624
LIG_FHA_2	64	70	PF00498	0.557
LIG_FHA_2	783	789	PF00498	0.673
LIG_FHA_2	793	799	PF00498	0.675
LIG_FHA_2	853	859	PF00498	0.755
LIG_FHA_2	860	866	PF00498	0.735
LIG_Integrin_isoDGR_2	132	134	PF01839	0.673
LIG_Integrin_RGD_1	150	152	PF01839	0.633
LIG_LIR_Gen_1	435	442	PF02991	0.664
LIG_LIR_Gen_1	461	469	PF02991	0.648
LIG_LIR_Gen_1	546	556	PF02991	0.630
LIG_LIR_Nem_3	435	441	PF02991	0.665
LIG_LIR_Nem_3	461	467	PF02991	0.651
LIG_LIR_Nem_3	546	552	PF02991	0.626
LIG_MYND_1	350	354	PF01753	0.565
LIG_REV1ctd_RIR_1	230	239	PF16727	0.690
LIG_SH2_CRK	464	468	PF00017	0.701
LIG_SH2_NCK_1	464	468	PF00017	0.701
LIG_SH2_STAP1	664	668	PF00017	0.694
LIG_SH2_STAT3	811	814	PF00017	0.656
LIG_SH2_STAT5	307	310	PF00017	0.707
LIG_SH2_STAT5	811	814	PF00017	0.656
LIG_SH2_STAT5	831	834	PF00017	0.671
LIG_SH3_1	558	564	PF00018	0.723
LIG_SH3_2	625	630	PF14604	0.657
LIG_SH3_3	323	329	PF00018	0.695
LIG_SH3_3	348	354	PF00018	0.652
LIG_SH3_3	389	395	PF00018	0.650
LIG_SH3_3	480	486	PF00018	0.698
LIG_SH3_3	496	502	PF00018	0.557
LIG_SH3_3	558	564	PF00018	0.697
LIG_SH3_3	621	627	PF00018	0.719
LIG_SH3_3	872	878	PF00018	0.568
LIG_SUMO_SIM_anti_2	197	203	PF11976	0.579
LIG_SUMO_SIM_anti_2	885	894	PF11976	0.629
LIG_SUMO_SIM_par_1	569	581	PF11976	0.705
LIG_TRAF2_1	181	184	PF00917	0.725
LIG_TRAF2_1	30	33	PF00917	0.585
LIG_TYR_ITIM	462	467	PF00017	0.701
LIG_WW_3	75	79	PF00397	0.678
MOD_CDK_SPxxK_3	623	630	PF00069	0.686
MOD_CK1_1	126	132	PF00069	0.688
MOD_CK1_1	164	170	PF00069	0.660
MOD_CK1_1	206	212	PF00069	0.699
MOD_CK1_1	227	233	PF00069	0.656
MOD_CK1_1	239	245	PF00069	0.625
MOD_CK1_1	257	263	PF00069	0.539
MOD_CK1_1	27	33	PF00069	0.609
MOD_CK1_1	279	285	PF00069	0.634
MOD_CK1_1	318	324	PF00069	0.638
MOD_CK1_1	325	331	PF00069	0.586
MOD_CK1_1	339	345	PF00069	0.595
MOD_CK1_1	359	365	PF00069	0.596
MOD_CK1_1	397	403	PF00069	0.734
MOD_CK1_1	436	442	PF00069	0.681
MOD_CK1_1	474	480	PF00069	0.621
MOD_CK1_1	541	547	PF00069	0.681
MOD_CK1_1	586	592	PF00069	0.823
MOD_CK1_1	623	629	PF00069	0.709
MOD_CK1_1	809	815	PF00069	0.740
MOD_CK1_1	81	87	PF00069	0.560
MOD_CK1_1	830	836	PF00069	0.700
MOD_CK1_1	882	888	PF00069	0.644
MOD_CK1_1	89	95	PF00069	0.610
MOD_CK2_1	177	183	PF00069	0.723
MOD_CK2_1	239	245	PF00069	0.625
MOD_CK2_1	25	31	PF00069	0.690
MOD_CK2_1	325	331	PF00069	0.584
MOD_CK2_1	385	391	PF00069	0.600
MOD_CK2_1	423	429	PF00069	0.627
MOD_CK2_1	475	481	PF00069	0.668
MOD_CK2_1	571	577	PF00069	0.727
MOD_CK2_1	631	637	PF00069	0.667
MOD_CK2_1	791	797	PF00069	0.689
MOD_CK2_1	80	86	PF00069	0.681
MOD_Cter_Amidation	768	771	PF01082	0.601
MOD_DYRK1A_RPxSP_1	94	98	PF00069	0.681
MOD_GlcNHglycan	1	4	PF01048	0.644
MOD_GlcNHglycan	125	128	PF01048	0.699
MOD_GlcNHglycan	163	166	PF01048	0.696
MOD_GlcNHglycan	179	182	PF01048	0.594
MOD_GlcNHglycan	212	215	PF01048	0.706
MOD_GlcNHglycan	226	229	PF01048	0.599
MOD_GlcNHglycan	256	259	PF01048	0.632
MOD_GlcNHglycan	269	272	PF01048	0.586
MOD_GlcNHglycan	366	369	PF01048	0.685
MOD_GlcNHglycan	417	420	PF01048	0.676
MOD_GlcNHglycan	435	438	PF01048	0.547
MOD_GlcNHglycan	446	449	PF01048	0.634
MOD_GlcNHglycan	45	48	PF01048	0.680
MOD_GlcNHglycan	450	453	PF01048	0.590
MOD_GlcNHglycan	456	459	PF01048	0.583
MOD_GlcNHglycan	467	470	PF01048	0.534
MOD_GlcNHglycan	507	510	PF01048	0.676
MOD_GlcNHglycan	511	514	PF01048	0.639
MOD_GlcNHglycan	569	572	PF01048	0.684
MOD_GlcNHglycan	591	594	PF01048	0.788
MOD_GlcNHglycan	634	637	PF01048	0.710
MOD_GlcNHglycan	646	649	PF01048	0.653
MOD_GlcNHglycan	695	698	PF01048	0.677
MOD_GlcNHglycan	727	730	PF01048	0.595
MOD_GlcNHglycan	780	783	PF01048	0.632
MOD_GlcNHglycan	797	802	PF01048	0.599
MOD_GlcNHglycan	806	809	PF01048	0.531
MOD_GlcNHglycan	832	835	PF01048	0.709
MOD_GlcNHglycan	867	870	PF01048	0.710
MOD_GSK3_1	107	114	PF00069	0.572
MOD_GSK3_1	123	130	PF00069	0.632
MOD_GSK3_1	173	180	PF00069	0.649
MOD_GSK3_1	202	209	PF00069	0.695
MOD_GSK3_1	267	274	PF00069	0.586
MOD_GSK3_1	275	282	PF00069	0.650
MOD_GSK3_1	305	312	PF00069	0.668
MOD_GSK3_1	315	322	PF00069	0.590
MOD_GSK3_1	336	343	PF00069	0.711
MOD_GSK3_1	356	363	PF00069	0.593
MOD_GSK3_1	371	378	PF00069	0.581
MOD_GSK3_1	391	398	PF00069	0.544
MOD_GSK3_1	406	413	PF00069	0.566
MOD_GSK3_1	429	436	PF00069	0.679
MOD_GSK3_1	43	50	PF00069	0.680
MOD_GSK3_1	444	451	PF00069	0.596
MOD_GSK3_1	454	461	PF00069	0.589
MOD_GSK3_1	471	478	PF00069	0.596
MOD_GSK3_1	493	500	PF00069	0.719
MOD_GSK3_1	505	512	PF00069	0.593
MOD_GSK3_1	538	545	PF00069	0.710
MOD_GSK3_1	567	574	PF00069	0.676
MOD_GSK3_1	584	591	PF00069	0.789
MOD_GSK3_1	59	66	PF00069	0.547
MOD_GSK3_1	616	623	PF00069	0.733
MOD_GSK3_1	644	651	PF00069	0.635
MOD_GSK3_1	689	696	PF00069	0.612
MOD_GSK3_1	760	767	PF00069	0.740
MOD_GSK3_1	778	785	PF00069	0.524
MOD_GSK3_1	797	804	PF00069	0.641
MOD_GSK3_1	86	93	PF00069	0.675
MOD_GSK3_1	865	872	PF00069	0.725
MOD_GSK3_1	94	101	PF00069	0.623
MOD_N-GLC_1	25	30	PF02516	0.558
MOD_N-GLC_1	764	769	PF02516	0.711
MOD_N-GLC_1	809	814	PF02516	0.639
MOD_NEK2_1	107	112	PF00069	0.551
MOD_NEK2_1	125	130	PF00069	0.673
MOD_NEK2_1	135	140	PF00069	0.620
MOD_NEK2_1	172	177	PF00069	0.659
MOD_NEK2_1	360	365	PF00069	0.563
MOD_NEK2_1	543	548	PF00069	0.647
MOD_NEK2_1	63	68	PF00069	0.602
MOD_NEK2_1	644	649	PF00069	0.635
MOD_NEK2_1	87	92	PF00069	0.680
MOD_NEK2_1	871	876	PF00069	0.592
MOD_NEK2_2	375	380	PF00069	0.620
MOD_NEK2_2	538	543	PF00069	0.586
MOD_NEK2_2	801	806	PF00069	0.666
MOD_PIKK_1	522	528	PF00454	0.667
MOD_PIKK_1	543	549	PF00454	0.648
MOD_PK_1	607	613	PF00069	0.616
MOD_PKA_2	123	129	PF00069	0.663
MOD_PKA_2	133	139	PF00069	0.670
MOD_PKA_2	185	191	PF00069	0.713
MOD_PKA_2	319	325	PF00069	0.617
MOD_PKA_2	339	345	PF00069	0.572
MOD_PKA_2	364	370	PF00069	0.613
MOD_PKA_2	444	450	PF00069	0.669
MOD_PKA_2	465	471	PF00069	0.691
MOD_PKA_2	53	59	PF00069	0.656
MOD_PKA_2	538	544	PF00069	0.667
MOD_PKA_2	583	589	PF00069	0.686
MOD_PKA_2	792	798	PF00069	0.647
MOD_PKA_2	869	875	PF00069	0.592
MOD_PKA_2	902	908	PF00069	0.633
MOD_PKA_2	93	99	PF00069	0.678
MOD_Plk_1	891	897	PF00069	0.733
MOD_Plk_4	458	464	PF00069	0.650
MOD_Plk_4	475	481	PF00069	0.559
MOD_Plk_4	538	544	PF00069	0.582
MOD_Plk_4	571	577	PF00069	0.718
MOD_Plk_4	59	65	PF00069	0.547
MOD_Plk_4	827	833	PF00069	0.677
MOD_Plk_4	871	877	PF00069	0.594
MOD_Plk_4	885	891	PF00069	0.649
MOD_ProDKin_1	164	170	PF00069	0.720
MOD_ProDKin_1	204	210	PF00069	0.688
MOD_ProDKin_1	236	242	PF00069	0.641
MOD_ProDKin_1	279	285	PF00069	0.653
MOD_ProDKin_1	325	331	PF00069	0.717
MOD_ProDKin_1	371	377	PF00069	0.601
MOD_ProDKin_1	391	397	PF00069	0.612
MOD_ProDKin_1	423	429	PF00069	0.651
MOD_ProDKin_1	450	456	PF00069	0.661
MOD_ProDKin_1	495	501	PF00069	0.682
MOD_ProDKin_1	531	537	PF00069	0.674
MOD_ProDKin_1	584	590	PF00069	0.683
MOD_ProDKin_1	620	626	PF00069	0.720
MOD_ProDKin_1	637	643	PF00069	0.679
MOD_ProDKin_1	68	74	PF00069	0.544
MOD_ProDKin_1	94	100	PF00069	0.683
MOD_SUMO_rev_2	857	862	PF00179	0.588
TRG_DiLeu_BaLyEn_6	639	644	PF01217	0.654
TRG_ENDOCYTIC_2	464	467	PF00928	0.706
TRG_ER_diArg_1	17	20	PF00400	0.687
TRG_ER_diArg_1	768	771	PF00400	0.685
TRG_ER_diArg_1	846	849	PF00400	0.579
TRG_ER_diArg_1	902	904	PF00400	0.665
TRG_NLS_MonoExtC_3	671	676	PF00514	0.677
TRG_NLS_MonoExtN_4	669	676	PF00514	0.671

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HDJ8	Leishmania braziliensis	56%	99%
A4I0Y3	Leishmania infantum	99%	100%
E9ACS9	Leishmania major	84%	100%
E9AWY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%