LSM domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ID22_LEIDO

TriTrypDb:

LdBPK_281060.1 , LdCL_280015200 , LDHU3_28.1270

Length:

165

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID22

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID22

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.499
CLV_NRD_NRD_1	46	48	PF00675	0.452
CLV_PCSK_KEX2_1	124	126	PF00082	0.555
CLV_PCSK_KEX2_1	46	48	PF00082	0.452
CLV_PCSK_SKI1_1	46	50	PF00082	0.482
DOC_CKS1_1	142	147	PF01111	0.537
DOC_MAPK_gen_1	28	35	PF00069	0.645
DOC_MAPK_gen_1	46	52	PF00069	0.316
DOC_PP2B_LxvP_1	147	150	PF13499	0.625
DOC_USP7_MATH_1	85	89	PF00917	0.668
DOC_USP7_MATH_2	150	156	PF00917	0.536
DOC_WW_Pin1_4	141	146	PF00397	0.460
DOC_WW_Pin1_4	21	26	PF00397	0.657
LIG_14-3-3_CanoR_1	12	18	PF00244	0.576
LIG_14-3-3_CanoR_1	129	135	PF00244	0.503
LIG_14-3-3_CanoR_1	46	51	PF00244	0.501
LIG_14-3-3_CanoR_1	80	84	PF00244	0.539
LIG_BIR_II_1	1	5	PF00653	0.636
LIG_BRCT_BRCA1_1	115	119	PF00533	0.521
LIG_FHA_1	142	148	PF00498	0.514
LIG_FHA_1	47	53	PF00498	0.506
LIG_FHA_2	106	112	PF00498	0.683
LIG_LIR_Gen_1	137	147	PF02991	0.459
LIG_LIR_Gen_1	38	48	PF02991	0.588
LIG_LIR_Nem_3	137	142	PF02991	0.452
LIG_LIR_Nem_3	38	44	PF02991	0.519
LIG_PDZ_Class_1	160	165	PF00595	0.634
LIG_PTB_Apo_2	133	140	PF02174	0.456
LIG_SH2_STAP1	37	41	PF00017	0.532
LIG_SH2_STAT5	81	84	PF00017	0.545
LIG_SH3_1	15	21	PF00018	0.720
LIG_SH3_3	15	21	PF00018	0.761
LIG_SUMO_SIM_par_1	48	53	PF11976	0.453
LIG_TRAF2_1	110	113	PF00917	0.674
LIG_TRAF2_1	89	92	PF00917	0.767
LIG_TYR_ITIM	35	40	PF00017	0.544
MOD_CDK_SPxxK_3	21	28	PF00069	0.663
MOD_CK1_1	128	134	PF00069	0.510
MOD_CK1_1	65	71	PF00069	0.481
MOD_CK1_1	8	14	PF00069	0.709
MOD_CK1_1	86	92	PF00069	0.667
MOD_CK2_1	105	111	PF00069	0.717
MOD_CK2_1	85	91	PF00069	0.751
MOD_Cter_Amidation	44	47	PF01082	0.469
MOD_GlcNHglycan	1	4	PF01048	0.640
MOD_GlcNHglycan	136	139	PF01048	0.479
MOD_GlcNHglycan	154	157	PF01048	0.642
MOD_GlcNHglycan	18	21	PF01048	0.675
MOD_GlcNHglycan	25	28	PF01048	0.741
MOD_GlcNHglycan	7	10	PF01048	0.654
MOD_GSK3_1	46	53	PF00069	0.472
MOD_GSK3_1	79	86	PF00069	0.622
MOD_N-GLC_1	28	33	PF02516	0.531
MOD_N-GLC_1	5	10	PF02516	0.696
MOD_NEK2_1	134	139	PF00069	0.464
MOD_NEK2_1	59	64	PF00069	0.501
MOD_PIKK_1	128	134	PF00454	0.510
MOD_PIKK_1	53	59	PF00454	0.630
MOD_PKA_1	46	52	PF00069	0.503
MOD_PKA_2	11	17	PF00069	0.711
MOD_PKA_2	128	134	PF00069	0.510
MOD_PKA_2	152	158	PF00069	0.545
MOD_PKA_2	46	52	PF00069	0.487
MOD_PKA_2	79	85	PF00069	0.626
MOD_PKA_2	86	92	PF00069	0.514
MOD_Plk_1	28	34	PF00069	0.521
MOD_Plk_4	143	149	PF00069	0.565
MOD_Plk_4	46	52	PF00069	0.466
MOD_ProDKin_1	141	147	PF00069	0.521
MOD_ProDKin_1	21	27	PF00069	0.652
TRG_ENDOCYTIC_2	37	40	PF00928	0.531
TRG_ER_diArg_1	46	48	PF00400	0.452

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHV6	Leptomonas seymouri	63%	100%
A0A422MZL4	Trypanosoma rangeli	41%	100%
A4HGE1	Leishmania braziliensis	75%	100%
A4I3H4	Leishmania infantum	100%	100%
E9AZR3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q8H0	Leishmania major	90%	100%