Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ID13_LEIDO

TriTrypDb:

LdBPK_242070.1 , LdCL_240026400 , LDHU3_24.2520

Length:

342

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID13

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	246	250	PF00656	0.700
CLV_NRD_NRD_1	110	112	PF00675	0.524
CLV_NRD_NRD_1	312	314	PF00675	0.673
CLV_NRD_NRD_1	37	39	PF00675	0.534
CLV_NRD_NRD_1	78	80	PF00675	0.512
CLV_NRD_NRD_1	86	88	PF00675	0.527
CLV_NRD_NRD_1	97	99	PF00675	0.385
CLV_PCSK_FUR_1	310	314	PF00082	0.623
CLV_PCSK_KEX2_1	312	314	PF00082	0.673
CLV_PCSK_KEX2_1	37	39	PF00082	0.508
CLV_PCSK_KEX2_1	78	80	PF00082	0.557
CLV_PCSK_KEX2_1	86	88	PF00082	0.517
CLV_PCSK_KEX2_1	97	99	PF00082	0.385
CLV_PCSK_SKI1_1	160	164	PF00082	0.731
CLV_PCSK_SKI1_1	79	83	PF00082	0.508
CLV_PCSK_SKI1_1	87	91	PF00082	0.485
DOC_MAPK_MEF2A_6	292	299	PF00069	0.662
DOC_PP1_RVXF_1	5	11	PF00149	0.667
DOC_PP2B_LxvP_1	322	325	PF13499	0.608
DOC_USP7_MATH_1	201	205	PF00917	0.702
DOC_USP7_MATH_1	220	224	PF00917	0.424
DOC_USP7_MATH_1	236	240	PF00917	0.739
LIG_14-3-3_CanoR_1	171	180	PF00244	0.543
LIG_14-3-3_CanoR_1	203	210	PF00244	0.679
LIG_14-3-3_CanoR_1	211	216	PF00244	0.536
LIG_14-3-3_CanoR_1	86	94	PF00244	0.580
LIG_BIR_III_4	237	241	PF00653	0.718
LIG_FHA_1	263	269	PF00498	0.628
LIG_FHA_2	321	327	PF00498	0.539
LIG_FHA_2	88	94	PF00498	0.643
LIG_LIR_Nem_3	51	57	PF02991	0.574
LIG_Pex14_1	170	174	PF04695	0.732
LIG_SH2_CRK	3	7	PF00017	0.591
LIG_SH2_GRB2like	16	19	PF00017	0.642
LIG_SH2_SRC	113	116	PF00017	0.624
LIG_SH2_STAP1	16	20	PF00017	0.634
LIG_SH2_STAT5	11	14	PF00017	0.578
LIG_SH2_STAT5	147	150	PF00017	0.561
LIG_SH2_STAT5	195	198	PF00017	0.586
LIG_SH3_1	155	161	PF00018	0.612
LIG_SH3_2	311	316	PF14604	0.739
LIG_SH3_3	155	161	PF00018	0.607
LIG_SH3_3	308	314	PF00018	0.689
MOD_CK1_1	173	179	PF00069	0.665
MOD_CK1_1	267	273	PF00069	0.596
MOD_CK1_1	287	293	PF00069	0.723
MOD_CK1_1	96	102	PF00069	0.612
MOD_CK2_1	320	326	PF00069	0.544
MOD_CK2_1	87	93	PF00069	0.601
MOD_GlcNHglycan	119	122	PF01048	0.650
MOD_GlcNHglycan	203	206	PF01048	0.643
MOD_GlcNHglycan	237	241	PF01048	0.725
MOD_GlcNHglycan	245	248	PF01048	0.761
MOD_GSK3_1	267	274	PF00069	0.622
MOD_GSK3_1	284	291	PF00069	0.728
MOD_GSK3_1	312	319	PF00069	0.688
MOD_GSK3_1	81	88	PF00069	0.648
MOD_N-GLC_1	320	325	PF02516	0.645
MOD_NEK2_1	117	122	PF00069	0.659
MOD_NEK2_1	163	168	PF00069	0.682
MOD_NEK2_1	284	289	PF00069	0.722
MOD_NEK2_1	297	302	PF00069	0.660
MOD_NEK2_1	336	341	PF00069	0.685
MOD_NEK2_2	81	86	PF00069	0.470
MOD_PIKK_1	203	209	PF00454	0.681
MOD_PK_1	30	36	PF00069	0.588
MOD_PKA_1	312	318	PF00069	0.677
MOD_PKA_2	170	176	PF00069	0.707
MOD_PKA_2	243	249	PF00069	0.828
MOD_PKA_2	312	318	PF00069	0.726
MOD_PKA_2	85	91	PF00069	0.683
MOD_PKA_2	96	102	PF00069	0.539
MOD_PKB_1	253	261	PF00069	0.585
MOD_PKB_1	310	318	PF00069	0.554
MOD_Plk_1	220	226	PF00069	0.634
MOD_Plk_1	320	326	PF00069	0.543
MOD_Plk_2-3	320	326	PF00069	0.608
MOD_Plk_4	264	270	PF00069	0.619
MOD_Plk_4	336	342	PF00069	0.697
TRG_DiLeu_BaEn_4	71	77	PF01217	0.582
TRG_ENDOCYTIC_2	16	19	PF00928	0.584
TRG_ER_diArg_1	253	256	PF00400	0.594
TRG_ER_diArg_1	309	312	PF00400	0.668
TRG_ER_diArg_1	78	80	PF00400	0.602
TRG_ER_diArg_1	97	100	PF00400	0.424
TRG_Pf-PMV_PEXEL_1	38	43	PF00026	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3P5	Leptomonas seymouri	52%	98%
A0A1X0NWD2	Trypanosomatidae	29%	100%
A0A422NWQ4	Trypanosoma rangeli	35%	100%
A4HDR1	Leishmania braziliensis	73%	99%
A4I107	Leishmania infantum	97%	100%
C9ZWA2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9AX45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QAD1	Leishmania major	91%	100%
V5BJJ9	Trypanosoma cruzi	34%	99%