Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ID10_LEIDO

TriTrypDb:

LdBPK_261810.1 , LdCL_260023700 , LDHU3_26.2370

Length:

498

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	104	108	PF00656	0.601
CLV_NRD_NRD_1	135	137	PF00675	0.710
CLV_NRD_NRD_1	317	319	PF00675	0.696
CLV_NRD_NRD_1	323	325	PF00675	0.686
CLV_NRD_NRD_1	352	354	PF00675	0.664
CLV_NRD_NRD_1	38	40	PF00675	0.580
CLV_NRD_NRD_1	426	428	PF00675	0.643
CLV_NRD_NRD_1	429	431	PF00675	0.626
CLV_NRD_NRD_1	61	63	PF00675	0.541
CLV_NRD_NRD_1	64	66	PF00675	0.563
CLV_PCSK_FUR_1	132	136	PF00082	0.680
CLV_PCSK_FUR_1	427	431	PF00082	0.636
CLV_PCSK_FUR_1	62	66	PF00082	0.648
CLV_PCSK_KEX2_1	134	136	PF00082	0.711
CLV_PCSK_KEX2_1	317	319	PF00082	0.697
CLV_PCSK_KEX2_1	323	325	PF00082	0.684
CLV_PCSK_KEX2_1	331	333	PF00082	0.639
CLV_PCSK_KEX2_1	377	379	PF00082	0.574
CLV_PCSK_KEX2_1	38	40	PF00082	0.580
CLV_PCSK_KEX2_1	426	428	PF00082	0.729
CLV_PCSK_KEX2_1	429	431	PF00082	0.689
CLV_PCSK_KEX2_1	61	63	PF00082	0.541
CLV_PCSK_KEX2_1	64	66	PF00082	0.563
CLV_PCSK_PC1ET2_1	331	333	PF00082	0.639
CLV_PCSK_PC1ET2_1	377	379	PF00082	0.574
CLV_PCSK_PC7_1	57	63	PF00082	0.640
CLV_PCSK_SKI1_1	218	222	PF00082	0.720
CLV_PCSK_SKI1_1	326	330	PF00082	0.651
DEG_APCC_DBOX_1	150	158	PF00400	0.622
DEG_APCC_DBOX_1	159	167	PF00400	0.642
DEG_SCF_TRCP1_1	279	285	PF00400	0.550
DEG_SPOP_SBC_1	390	394	PF00917	0.773
DOC_CKS1_1	408	413	PF01111	0.747
DOC_MAPK_gen_1	134	144	PF00069	0.782
DOC_MAPK_gen_1	93	102	PF00069	0.570
DOC_MAPK_MEF2A_6	138	146	PF00069	0.759
DOC_MAPK_RevD_3	24	39	PF00069	0.599
DOC_PP2B_LxvP_1	257	260	PF13499	0.707
DOC_PP2B_LxvP_1	34	37	PF13499	0.639
DOC_PP4_FxxP_1	439	442	PF00568	0.620
DOC_PP4_FxxP_1	75	78	PF00568	0.580
DOC_USP7_MATH_1	158	162	PF00917	0.726
DOC_USP7_MATH_1	169	173	PF00917	0.661
DOC_USP7_MATH_1	252	256	PF00917	0.752
DOC_USP7_MATH_1	28	32	PF00917	0.693
DOC_USP7_MATH_1	344	348	PF00917	0.587
DOC_USP7_MATH_1	364	368	PF00917	0.491
DOC_USP7_MATH_1	388	392	PF00917	0.781
DOC_USP7_MATH_1	404	408	PF00917	0.506
DOC_WW_Pin1_4	190	195	PF00397	0.731
DOC_WW_Pin1_4	210	215	PF00397	0.535
DOC_WW_Pin1_4	220	225	PF00397	0.707
DOC_WW_Pin1_4	232	237	PF00397	0.765
DOC_WW_Pin1_4	260	265	PF00397	0.795
DOC_WW_Pin1_4	279	284	PF00397	0.515
DOC_WW_Pin1_4	379	384	PF00397	0.817
DOC_WW_Pin1_4	407	412	PF00397	0.752
LIG_14-3-3_CanoR_1	135	144	PF00244	0.683
LIG_14-3-3_CanoR_1	18	26	PF00244	0.591
LIG_14-3-3_CanoR_1	200	204	PF00244	0.703
LIG_14-3-3_CanoR_1	246	256	PF00244	0.713
LIG_14-3-3_CanoR_1	98	103	PF00244	0.637
LIG_Actin_WH2_2	150	166	PF00022	0.603
LIG_APCC_ABBA_1	461	466	PF00400	0.631
LIG_APCC_ABBAyCdc20_2	71	77	PF00400	0.595
LIG_CaM_IQ_9	85	100	PF13499	0.534
LIG_Clathr_ClatBox_1	275	279	PF01394	0.545
LIG_CtBP_PxDLS_1	307	311	PF00389	0.586
LIG_FHA_1	124	130	PF00498	0.697
LIG_FHA_1	137	143	PF00498	0.691
LIG_FHA_1	21	27	PF00498	0.779
LIG_FHA_1	260	266	PF00498	0.701
LIG_FHA_1	343	349	PF00498	0.777
LIG_FHA_1	408	414	PF00498	0.742
LIG_FHA_1	6	12	PF00498	0.733
LIG_FHA_2	145	151	PF00498	0.606
LIG_FHA_2	286	292	PF00498	0.799
LIG_FHA_2	44	50	PF00498	0.640
LIG_Integrin_isoDGR_2	241	243	PF01839	0.661
LIG_LIR_Apic_2	72	78	PF02991	0.598
LIG_LIR_Gen_1	446	451	PF02991	0.556
LIG_LIR_Nem_3	446	450	PF02991	0.545
LIG_MAD2	474	482	PF02301	0.648
LIG_MYND_1	33	37	PF01753	0.593
LIG_RPA_C_Fungi	312	324	PF08784	0.683
LIG_SH2_CRK	219	223	PF00017	0.645
LIG_SH2_CRK	401	405	PF00017	0.755
LIG_SH2_CRK	447	451	PF00017	0.552
LIG_SH2_NCK_1	219	223	PF00017	0.645
LIG_SH2_PTP2	99	102	PF00017	0.595
LIG_SH2_STAP1	170	174	PF00017	0.625
LIG_SH2_STAP1	447	451	PF00017	0.552
LIG_SH2_STAT3	86	89	PF00017	0.684
LIG_SH2_STAT5	153	156	PF00017	0.582
LIG_SH2_STAT5	443	446	PF00017	0.647
LIG_SH2_STAT5	447	450	PF00017	0.572
LIG_SH2_STAT5	67	70	PF00017	0.508
LIG_SH2_STAT5	99	102	PF00017	0.785
LIG_SH3_1	27	33	PF00018	0.600
LIG_SH3_2	211	216	PF14604	0.815
LIG_SH3_3	208	214	PF00018	0.786
LIG_SH3_3	27	33	PF00018	0.693
LIG_SH3_3	8	14	PF00018	0.824
LIG_SUMO_SIM_anti_2	418	424	PF11976	0.629
LIG_SUMO_SIM_par_1	139	148	PF11976	0.667
LIG_TRAF2_1	482	485	PF00917	0.694
MOD_CDC14_SPxK_1	197	200	PF00782	0.829
MOD_CDC14_SPxK_1	213	216	PF00782	0.780
MOD_CDK_SPK_2	220	225	PF00069	0.624
MOD_CDK_SPK_2	279	284	PF00069	0.737
MOD_CDK_SPxK_1	190	196	PF00069	0.779
MOD_CDK_SPxK_1	210	216	PF00069	0.539
MOD_CDK_SPxxK_3	236	243	PF00069	0.714
MOD_CDK_SPxxK_3	260	267	PF00069	0.789
MOD_CK1_1	101	107	PF00069	0.678
MOD_CK1_1	137	143	PF00069	0.774
MOD_CK1_1	16	22	PF00069	0.715
MOD_CK1_1	172	178	PF00069	0.639
MOD_CK1_1	186	192	PF00069	0.627
MOD_CK1_1	247	253	PF00069	0.713
MOD_CK1_1	285	291	PF00069	0.760
MOD_CK1_1	391	397	PF00069	0.782
MOD_CK1_1	407	413	PF00069	0.537
MOD_CK2_1	125	131	PF00069	0.821
MOD_CK2_1	144	150	PF00069	0.569
MOD_CK2_1	285	291	PF00069	0.766
MOD_GlcNHglycan	104	107	PF01048	0.649
MOD_GlcNHglycan	15	18	PF01048	0.703
MOD_GlcNHglycan	159	163	PF01048	0.716
MOD_GlcNHglycan	173	177	PF01048	0.574
MOD_GlcNHglycan	252	255	PF01048	0.758
MOD_GlcNHglycan	279	282	PF01048	0.826
MOD_GlcNHglycan	319	322	PF01048	0.691
MOD_GlcNHglycan	490	493	PF01048	0.626
MOD_GSK3_1	13	20	PF00069	0.799
MOD_GSK3_1	134	141	PF00069	0.737
MOD_GSK3_1	183	190	PF00069	0.792
MOD_GSK3_1	220	227	PF00069	0.751
MOD_GSK3_1	232	239	PF00069	0.738
MOD_GSK3_1	244	251	PF00069	0.707
MOD_GSK3_1	445	452	PF00069	0.628
MOD_GSK3_1	98	105	PF00069	0.660
MOD_LATS_1	315	321	PF00433	0.799
MOD_N-GLC_1	260	265	PF02516	0.701
MOD_NEK2_1	185	190	PF00069	0.828
MOD_NEK2_1	245	250	PF00069	0.804
MOD_NEK2_1	85	90	PF00069	0.669
MOD_NEK2_2	344	349	PF00069	0.588
MOD_PIKK_1	245	251	PF00454	0.730
MOD_PIKK_1	402	408	PF00454	0.764
MOD_PIKK_1	449	455	PF00454	0.577
MOD_PIKK_1	85	91	PF00454	0.689
MOD_PK_1	138	144	PF00069	0.700
MOD_PK_1	98	104	PF00069	0.689
MOD_PKA_1	134	140	PF00069	0.656
MOD_PKA_1	317	323	PF00069	0.692
MOD_PKA_2	134	140	PF00069	0.689
MOD_PKA_2	17	23	PF00069	0.536
MOD_PKA_2	199	205	PF00069	0.742
MOD_PKA_2	245	251	PF00069	0.720
MOD_PKA_2	317	323	PF00069	0.692
MOD_PKB_1	132	140	PF00069	0.672
MOD_PKB_1	96	104	PF00069	0.777
MOD_Plk_1	445	451	PF00069	0.657
MOD_Plk_4	252	258	PF00069	0.714
MOD_Plk_4	404	410	PF00069	0.663
MOD_Plk_4	416	422	PF00069	0.629
MOD_ProDKin_1	190	196	PF00069	0.732
MOD_ProDKin_1	210	216	PF00069	0.539
MOD_ProDKin_1	220	226	PF00069	0.708
MOD_ProDKin_1	232	238	PF00069	0.763
MOD_ProDKin_1	260	266	PF00069	0.795
MOD_ProDKin_1	279	285	PF00069	0.515
MOD_ProDKin_1	379	385	PF00069	0.815
MOD_ProDKin_1	407	413	PF00069	0.747
MOD_SUMO_for_1	283	286	PF00179	0.693
MOD_SUMO_rev_2	373	379	PF00179	0.568
MOD_SUMO_rev_2	490	497	PF00179	0.721
TRG_DiLeu_BaLyEn_6	261	266	PF01217	0.773
TRG_DiLeu_BaLyEn_6	271	276	PF01217	0.680
TRG_DiLeu_BaLyEn_6	30	35	PF01217	0.598
TRG_ENDOCYTIC_2	399	402	PF00928	0.745
TRG_ENDOCYTIC_2	447	450	PF00928	0.637
TRG_ENDOCYTIC_2	67	70	PF00928	0.563
TRG_ENDOCYTIC_2	99	102	PF00928	0.689
TRG_ER_diArg_1	133	136	PF00400	0.717
TRG_ER_diArg_1	216	219	PF00400	0.646
TRG_ER_diArg_1	37	39	PF00400	0.586
TRG_ER_diArg_1	425	427	PF00400	0.727
TRG_ER_diArg_1	428	430	PF00400	0.686
TRG_ER_diArg_1	472	475	PF00400	0.669
TRG_ER_diArg_1	60	62	PF00400	0.530
TRG_ER_diArg_1	64	66	PF00400	0.554
TRG_ER_diArg_1	96	99	PF00400	0.771
TRG_NLS_Bipartite_1	317	335	PF00514	0.665
TRG_NLS_MonoExtN_4	350	357	PF00514	0.660
TRG_Pf-PMV_PEXEL_1	274	279	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	326	330	PF00026	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7B6	Leptomonas seymouri	34%	86%
A4HF27	Leishmania braziliensis	65%	100%
A4I2B4	Leishmania infantum	98%	100%
E9AYG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4Q911	Leishmania major	87%	100%