LeishMANIAdb
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CUPID domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CUPID domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8ID08_LEIDO
TriTrypDb:
LdBPK_320950.1 , LdCL_320015100 , LDHU3_32.1240
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID08
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID08

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 6 10 PF00656 0.682
CLV_NRD_NRD_1 87 89 PF00675 0.501
CLV_PCSK_KEX2_1 85 87 PF00082 0.495
CLV_PCSK_PC1ET2_1 85 87 PF00082 0.652
CLV_PCSK_PC7_1 82 88 PF00082 0.652
DOC_USP7_UBL2_3 97 101 PF12436 0.642
DOC_WW_Pin1_4 114 119 PF00397 0.643
LIG_BIR_II_1 1 5 PF00653 0.796
LIG_Clathr_ClatBox_1 108 112 PF01394 0.556
LIG_FHA_1 10 16 PF00498 0.659
LIG_NRBOX 25 31 PF00104 0.372
LIG_SH2_GRB2like 72 75 PF00017 0.500
LIG_SH2_STAT5 72 75 PF00017 0.500
LIG_TRAF2_1 44 47 PF00917 0.641
LIG_TRAF2_1 52 55 PF00917 0.517
LIG_TRAF2_1 63 66 PF00917 0.324
MOD_CAAXbox 130 133 PF01239 0.671
MOD_CDK_SPK_2 114 119 PF00069 0.643
MOD_CK1_1 17 23 PF00069 0.439
MOD_CK1_1 2 8 PF00069 0.763
MOD_CK2_1 114 120 PF00069 0.686
MOD_GSK3_1 1 8 PF00069 0.782
MOD_GSK3_1 110 117 PF00069 0.614
MOD_N-GLC_1 73 78 PF02516 0.636
MOD_NEK2_1 1 6 PF00069 0.720
MOD_NEK2_1 14 19 PF00069 0.520
MOD_NEK2_1 38 43 PF00069 0.605
MOD_NEK2_1 73 78 PF00069 0.574
MOD_PIKK_1 9 15 PF00454 0.581
MOD_PIKK_1 90 96 PF00454 0.640
MOD_Plk_1 73 79 PF00069 0.557
MOD_ProDKin_1 114 120 PF00069 0.640
TRG_DiLeu_BaEn_4 54 60 PF01217 0.644
TRG_DiLeu_BaEn_4 65 71 PF01217 0.453
TRG_ER_diArg_1 86 88 PF00400 0.505
TRG_NLS_MonoCore_2 84 89 PF00514 0.582
TRG_NLS_MonoExtC_3 84 90 PF00514 0.581
TRG_NLS_MonoExtN_4 82 89 PF00514 0.582

Homologs

Protein Taxonomy Sequence identity Coverage
A4HK71 Leishmania braziliensis 80% 100%
A4I7Q6 Leishmania infantum 99% 100%
E9B2L4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q5J2 Leishmania major 93% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS