Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ID03_LEIDO

TriTrypDb:

LdBPK_241930.1 , LdCL_240025000 , LDHU3_24.2370

Length:

536

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ID03

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ID03

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.667
CLV_C14_Caspase3-7	260	264	PF00656	0.611
CLV_NRD_NRD_1	209	211	PF00675	0.621
CLV_NRD_NRD_1	301	303	PF00675	0.687
CLV_NRD_NRD_1	318	320	PF00675	0.541
CLV_NRD_NRD_1	370	372	PF00675	0.623
CLV_PCSK_FUR_1	207	211	PF00082	0.618
CLV_PCSK_KEX2_1	20	22	PF00082	0.680
CLV_PCSK_KEX2_1	209	211	PF00082	0.621
CLV_PCSK_KEX2_1	300	302	PF00082	0.815
CLV_PCSK_KEX2_1	318	320	PF00082	0.547
CLV_PCSK_KEX2_1	370	372	PF00082	0.623
CLV_PCSK_KEX2_1	531	533	PF00082	0.615
CLV_PCSK_PC1ET2_1	20	22	PF00082	0.633
CLV_PCSK_PC1ET2_1	531	533	PF00082	0.615
CLV_PCSK_SKI1_1	344	348	PF00082	0.608
CLV_PCSK_SKI1_1	531	535	PF00082	0.621
DEG_APCC_DBOX_1	477	485	PF00400	0.524
DOC_CDC14_PxL_1	444	452	PF14671	0.579
DOC_CKS1_1	105	110	PF01111	0.715
DOC_CKS1_1	153	158	PF01111	0.656
DOC_CYCLIN_yCln2_LP_2	348	354	PF00134	0.646
DOC_MAPK_DCC_7	53	62	PF00069	0.646
DOC_MAPK_gen_1	461	469	PF00069	0.519
DOC_PP1_RVXF_1	414	420	PF00149	0.555
DOC_PP2B_LxvP_1	15	18	PF13499	0.660
DOC_PP2B_LxvP_1	87	90	PF13499	0.666
DOC_USP7_MATH_1	103	107	PF00917	0.617
DOC_USP7_MATH_1	234	238	PF00917	0.703
DOC_USP7_MATH_1	288	292	PF00917	0.722
DOC_USP7_MATH_1	296	300	PF00917	0.708
DOC_USP7_MATH_1	372	376	PF00917	0.692
DOC_USP7_MATH_1	393	397	PF00917	0.619
DOC_USP7_MATH_1	81	85	PF00917	0.696
DOC_USP7_MATH_2	311	317	PF00917	0.682
DOC_WW_Pin1_4	104	109	PF00397	0.674
DOC_WW_Pin1_4	152	157	PF00397	0.697
DOC_WW_Pin1_4	19	24	PF00397	0.652
DOC_WW_Pin1_4	217	222	PF00397	0.726
DOC_WW_Pin1_4	307	312	PF00397	0.729
DOC_WW_Pin1_4	335	340	PF00397	0.677
DOC_WW_Pin1_4	347	352	PF00397	0.582
DOC_WW_Pin1_4	42	47	PF00397	0.683
DOC_WW_Pin1_4	48	53	PF00397	0.653
DOC_WW_Pin1_4	514	519	PF00397	0.611
DOC_WW_Pin1_4	55	60	PF00397	0.588
LIG_14-3-3_CanoR_1	109	118	PF00244	0.613
LIG_14-3-3_CanoR_1	231	239	PF00244	0.704
LIG_14-3-3_CanoR_1	301	311	PF00244	0.639
LIG_14-3-3_CanoR_1	38	42	PF00244	0.614
LIG_14-3-3_CterR_2	532	536	PF00244	0.656
LIG_BIR_II_1	1	5	PF00653	0.629
LIG_BRCT_BRCA1_1	123	127	PF00533	0.625
LIG_CtBP_PxDLS_1	406	410	PF00389	0.599
LIG_EVH1_1	15	19	PF00568	0.660
LIG_FHA_1	160	166	PF00498	0.669
LIG_FHA_1	382	388	PF00498	0.635
LIG_FHA_1	439	445	PF00498	0.681
LIG_FHA_1	515	521	PF00498	0.618
LIG_FHA_2	114	120	PF00498	0.705
LIG_FHA_2	179	185	PF00498	0.572
LIG_FHA_2	28	34	PF00498	0.665
LIG_FHA_2	49	55	PF00498	0.685
LIG_LIR_Gen_1	505	512	PF02991	0.601
LIG_LIR_Nem_3	391	397	PF02991	0.638
LIG_LIR_Nem_3	460	466	PF02991	0.484
LIG_LIR_Nem_3	505	510	PF02991	0.597
LIG_SH2_CRK	153	157	PF00017	0.686
LIG_SH2_CRK	26	30	PF00017	0.653
LIG_SH2_CRK	463	467	PF00017	0.475
LIG_SH2_NCK_1	153	157	PF00017	0.653
LIG_SH2_NCK_1	26	30	PF00017	0.653
LIG_SH2_NCK_1	8	12	PF00017	0.631
LIG_SH2_STAT3	331	334	PF00017	0.638
LIG_SH2_STAT3	362	365	PF00017	0.610
LIG_SH2_STAT5	331	334	PF00017	0.638
LIG_SH3_2	16	21	PF14604	0.668
LIG_SH3_3	102	108	PF00018	0.671
LIG_SH3_3	13	19	PF00018	0.669
LIG_SH3_3	196	202	PF00018	0.612
LIG_SH3_3	442	448	PF00018	0.667
LIG_SH3_3	515	521	PF00018	0.653
LIG_SUMO_SIM_anti_2	383	391	PF11976	0.548
LIG_SUMO_SIM_par_1	349	355	PF11976	0.558
LIG_SUMO_SIM_par_1	383	391	PF11976	0.630
LIG_UBA3_1	466	475	PF00899	0.416
LIG_WW_1	23	26	PF00397	0.652
LIG_WW_3	22	26	PF00397	0.681
MOD_CDC14_SPxK_1	338	341	PF00782	0.630
MOD_CDC14_SPxK_1	45	48	PF00782	0.674
MOD_CDK_SPK_2	104	109	PF00069	0.660
MOD_CDK_SPK_2	48	53	PF00069	0.654
MOD_CDK_SPxK_1	19	25	PF00069	0.638
MOD_CDK_SPxK_1	335	341	PF00069	0.632
MOD_CDK_SPxK_1	42	48	PF00069	0.672
MOD_CK1_1	112	118	PF00069	0.685
MOD_CK1_1	125	131	PF00069	0.581
MOD_CK1_1	171	177	PF00069	0.678
MOD_CK1_1	232	238	PF00069	0.682
MOD_CK1_1	27	33	PF00069	0.735
MOD_CK1_1	291	297	PF00069	0.614
MOD_CK1_1	312	318	PF00069	0.729
MOD_CK1_1	323	329	PF00069	0.664
MOD_CK1_1	350	356	PF00069	0.578
MOD_CK1_1	380	386	PF00069	0.667
MOD_CK1_1	396	402	PF00069	0.530
MOD_CK1_1	429	435	PF00069	0.654
MOD_CK2_1	113	119	PF00069	0.713
MOD_CK2_1	178	184	PF00069	0.576
MOD_CK2_1	27	33	PF00069	0.650
MOD_CK2_1	302	308	PF00069	0.702
MOD_CK2_1	486	492	PF00069	0.470
MOD_DYRK1A_RPxSP_1	42	46	PF00069	0.658
MOD_DYRK1A_RPxSP_1	48	52	PF00069	0.602
MOD_GlcNHglycan	132	135	PF01048	0.642
MOD_GlcNHglycan	227	230	PF01048	0.827
MOD_GlcNHglycan	251	254	PF01048	0.663
MOD_GlcNHglycan	290	293	PF01048	0.707
MOD_GlcNHglycan	294	297	PF01048	0.684
MOD_GlcNHglycan	322	325	PF01048	0.772
MOD_GlcNHglycan	428	432	PF01048	0.675
MOD_GlcNHglycan	488	491	PF01048	0.469
MOD_GlcNHglycan	527	530	PF01048	0.553
MOD_GSK3_1	109	116	PF00069	0.668
MOD_GSK3_1	121	128	PF00069	0.581
MOD_GSK3_1	130	137	PF00069	0.600
MOD_GSK3_1	167	174	PF00069	0.761
MOD_GSK3_1	225	232	PF00069	0.825
MOD_GSK3_1	25	32	PF00069	0.691
MOD_GSK3_1	288	295	PF00069	0.736
MOD_GSK3_1	303	310	PF00069	0.630
MOD_GSK3_1	346	353	PF00069	0.660
MOD_GSK3_1	356	363	PF00069	0.594
MOD_GSK3_1	377	384	PF00069	0.664
MOD_GSK3_1	393	400	PF00069	0.681
MOD_GSK3_1	434	441	PF00069	0.638
MOD_GSK3_1	88	95	PF00069	0.686
MOD_LATS_1	307	313	PF00433	0.677
MOD_N-GLC_1	159	164	PF02516	0.684
MOD_N-GLC_1	178	183	PF02516	0.467
MOD_N-GLC_1	242	247	PF02516	0.592
MOD_NEK2_1	1	6	PF00069	0.627
MOD_NEK2_1	159	164	PF00069	0.668
MOD_NEK2_1	178	183	PF00069	0.434
MOD_NEK2_1	407	412	PF00069	0.609
MOD_NEK2_1	419	424	PF00069	0.556
MOD_NEK2_1	512	517	PF00069	0.588
MOD_NEK2_1	92	97	PF00069	0.612
MOD_NEK2_2	37	42	PF00069	0.581
MOD_NEK2_2	393	398	PF00069	0.642
MOD_PIKK_1	109	115	PF00454	0.675
MOD_PIKK_1	208	214	PF00454	0.658
MOD_PIKK_1	232	238	PF00454	0.607
MOD_PIKK_1	360	366	PF00454	0.655
MOD_PIKK_1	378	384	PF00454	0.642
MOD_PIKK_1	65	71	PF00454	0.704
MOD_PKA_1	370	376	PF00069	0.641
MOD_PKA_2	174	180	PF00069	0.618
MOD_PKA_2	208	214	PF00069	0.624
MOD_PKA_2	230	236	PF00069	0.707
MOD_PKA_2	24	30	PF00069	0.688
MOD_PKA_2	37	43	PF00069	0.533
MOD_PKA_2	370	376	PF00069	0.688
MOD_PKA_2	397	403	PF00069	0.697
MOD_PKA_2	426	432	PF00069	0.588
MOD_PKA_2	525	531	PF00069	0.580
MOD_PKA_2	65	71	PF00069	0.634
MOD_PKB_1	300	308	PF00069	0.623
MOD_PKB_1	425	433	PF00069	0.629
MOD_Plk_1	159	165	PF00069	0.645
MOD_Plk_1	312	318	PF00069	0.687
MOD_Plk_1	407	413	PF00069	0.598
MOD_Plk_2-3	168	174	PF00069	0.671
MOD_ProDKin_1	104	110	PF00069	0.673
MOD_ProDKin_1	152	158	PF00069	0.699
MOD_ProDKin_1	19	25	PF00069	0.656
MOD_ProDKin_1	217	223	PF00069	0.729
MOD_ProDKin_1	307	313	PF00069	0.731
MOD_ProDKin_1	335	341	PF00069	0.680
MOD_ProDKin_1	347	353	PF00069	0.580
MOD_ProDKin_1	42	48	PF00069	0.684
MOD_ProDKin_1	514	520	PF00069	0.614
MOD_ProDKin_1	55	61	PF00069	0.586
MOD_SUMO_for_1	474	477	PF00179	0.444
MOD_SUMO_rev_2	82	87	PF00179	0.725
TRG_DiLeu_BaEn_1	439	444	PF01217	0.681
TRG_DiLeu_BaEn_2	414	420	PF01217	0.555
TRG_DiLeu_BaLyEn_6	518	523	PF01217	0.668
TRG_ENDOCYTIC_2	26	29	PF00928	0.724
TRG_ENDOCYTIC_2	463	466	PF00928	0.522
TRG_ER_diArg_1	207	210	PF00400	0.619
TRG_ER_diArg_1	274	277	PF00400	0.600
TRG_ER_diArg_1	300	302	PF00400	0.692
TRG_ER_diArg_1	317	319	PF00400	0.590

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HDP7	Leishmania braziliensis	52%	99%
A4I0Z3	Leishmania infantum	100%	100%
E9AX31	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	97%
Q4QAE5	Leishmania major	87%	100%