DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA polymerase theta

Species:

Leishmania donovani

UniProt:

A0A3Q8ICZ6_LEIDO

TriTrypDb:

LdBPK_240910.1 , LdCL_240014100 , LDHU3_24.1080

Length:

1171

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8ICZ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICZ6

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006260	DNA replication	5	7
GO:0006261	DNA-templated DNA replication	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0000731	DNA synthesis involved in DNA repair	6	1
GO:0006281	DNA repair	5	1
GO:0006301	postreplication repair	6	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019985	translesion synthesis	7	1
GO:0033554	cellular response to stress	3	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071897	DNA biosynthetic process	5	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0003887	DNA-directed DNA polymerase activity	5	7
GO:0005488	binding	1	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016779	nucleotidyltransferase activity	4	7
GO:0034061	DNA polymerase activity	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	423	427	PF00656	0.785
CLV_C14_Caspase3-7	438	442	PF00656	0.581
CLV_C14_Caspase3-7	456	460	PF00656	0.554
CLV_MEL_PAP_1	1152	1158	PF00089	0.346
CLV_MEL_PAP_1	606	612	PF00089	0.546
CLV_NRD_NRD_1	1023	1025	PF00675	0.419
CLV_NRD_NRD_1	1054	1056	PF00675	0.346
CLV_NRD_NRD_1	1067	1069	PF00675	0.346
CLV_NRD_NRD_1	165	167	PF00675	0.779
CLV_NRD_NRD_1	193	195	PF00675	0.698
CLV_NRD_NRD_1	454	456	PF00675	0.621
CLV_NRD_NRD_1	514	516	PF00675	0.748
CLV_NRD_NRD_1	526	528	PF00675	0.651
CLV_NRD_NRD_1	7	9	PF00675	0.773
CLV_NRD_NRD_1	762	764	PF00675	0.647
CLV_PCSK_FUR_1	522	526	PF00082	0.739
CLV_PCSK_KEX2_1	1023	1025	PF00082	0.419
CLV_PCSK_KEX2_1	1066	1068	PF00082	0.346
CLV_PCSK_KEX2_1	193	195	PF00082	0.699
CLV_PCSK_KEX2_1	454	456	PF00082	0.621
CLV_PCSK_KEX2_1	513	515	PF00082	0.698
CLV_PCSK_KEX2_1	524	526	PF00082	0.726
CLV_PCSK_KEX2_1	7	9	PF00082	0.736
CLV_PCSK_KEX2_1	87	89	PF00082	0.801
CLV_PCSK_PC1ET2_1	513	515	PF00082	0.708
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.801
CLV_PCSK_PC7_1	1019	1025	PF00082	0.391
CLV_PCSK_PC7_1	520	526	PF00082	0.698
CLV_PCSK_SKI1_1	1019	1023	PF00082	0.391
CLV_PCSK_SKI1_1	250	254	PF00082	0.611
CLV_PCSK_SKI1_1	330	334	PF00082	0.538
CLV_PCSK_SKI1_1	340	344	PF00082	0.573
CLV_PCSK_SKI1_1	399	403	PF00082	0.645
CLV_PCSK_SKI1_1	514	518	PF00082	0.724
CLV_PCSK_SKI1_1	553	557	PF00082	0.626
CLV_Separin_Metazoa	1128	1132	PF03568	0.619
CLV_Separin_Metazoa	707	711	PF03568	0.730
DEG_APCC_DBOX_1	249	257	PF00400	0.595
DEG_APCC_DBOX_1	349	357	PF00400	0.710
DEG_APCC_DBOX_1	369	377	PF00400	0.412
DEG_APCC_DBOX_1	754	762	PF00400	0.609
DEG_COP1_1	670	677	PF00400	0.444
DEG_SCF_FBW7_2	172	178	PF00400	0.799
DEG_SCF_TRCP1_1	529	535	PF00400	0.663
DEG_SPOP_SBC_1	70	74	PF00917	0.788
DOC_CDC14_PxL_1	313	321	PF14671	0.570
DOC_CKS1_1	172	177	PF01111	0.797
DOC_CYCLIN_RxL_1	324	335	PF00134	0.553
DOC_CYCLIN_RxL_1	336	348	PF00134	0.570
DOC_CYCLIN_RxL_1	508	519	PF00134	0.785
DOC_CYCLIN_yCln2_LP_2	1146	1152	PF00134	0.546
DOC_CYCLIN_yCln2_LP_2	15	18	PF00134	0.760
DOC_MAPK_gen_1	1142	1152	PF00069	0.546
DOC_MAPK_gen_1	39	48	PF00069	0.762
DOC_MAPK_gen_1	763	771	PF00069	0.658
DOC_MAPK_gen_1	87	94	PF00069	0.777
DOC_MAPK_MEF2A_6	1142	1150	PF00069	0.546
DOC_MAPK_MEF2A_6	211	219	PF00069	0.629
DOC_MAPK_MEF2A_6	370	377	PF00069	0.744
DOC_MAPK_MEF2A_6	764	773	PF00069	0.740
DOC_MAPK_MEF2A_6	87	94	PF00069	0.777
DOC_MAPK_MEF2A_6	966	973	PF00069	0.546
DOC_PP1_RVXF_1	338	344	PF00149	0.563
DOC_PP2B_LxvP_1	1146	1149	PF13499	0.546
DOC_PP2B_LxvP_1	15	18	PF13499	0.721
DOC_PP2B_LxvP_1	323	326	PF13499	0.631
DOC_PP2B_LxvP_1	953	956	PF13499	0.546
DOC_PP4_FxxP_1	377	380	PF00568	0.762
DOC_USP7_MATH_1	1008	1012	PF00917	0.577
DOC_USP7_MATH_1	1043	1047	PF00917	0.619
DOC_USP7_MATH_1	122	126	PF00917	0.801
DOC_USP7_MATH_1	128	132	PF00917	0.702
DOC_USP7_MATH_1	252	256	PF00917	0.586
DOC_USP7_MATH_1	420	424	PF00917	0.721
DOC_USP7_MATH_1	578	582	PF00917	0.686
DOC_USP7_MATH_1	673	677	PF00917	0.679
DOC_USP7_MATH_1	68	72	PF00917	0.798
DOC_USP7_MATH_1	724	728	PF00917	0.665
DOC_USP7_MATH_1	777	781	PF00917	0.749
DOC_USP7_MATH_1	786	790	PF00917	0.668
DOC_USP7_MATH_1	794	798	PF00917	0.683
DOC_USP7_MATH_1	843	847	PF00917	0.540
DOC_USP7_UBL2_3	764	768	PF12436	0.658
DOC_WW_Pin1_4	118	123	PF00397	0.766
DOC_WW_Pin1_4	171	176	PF00397	0.795
DOC_WW_Pin1_4	24	29	PF00397	0.759
DOC_WW_Pin1_4	598	603	PF00397	0.640
DOC_WW_Pin1_4	608	613	PF00397	0.598
DOC_WW_Pin1_4	702	707	PF00397	0.714
DOC_WW_Pin1_4	78	83	PF00397	0.790
DOC_WW_Pin1_4	841	846	PF00397	0.579
LIG_14-3-3_CanoR_1	1055	1059	PF00244	0.546
LIG_14-3-3_CanoR_1	1095	1099	PF00244	0.619
LIG_14-3-3_CanoR_1	166	173	PF00244	0.778
LIG_14-3-3_CanoR_1	226	234	PF00244	0.592
LIG_14-3-3_CanoR_1	243	249	PF00244	0.644
LIG_14-3-3_CanoR_1	553	558	PF00244	0.514
LIG_14-3-3_CanoR_1	698	706	PF00244	0.563
LIG_14-3-3_CanoR_1	751	758	PF00244	0.640
LIG_14-3-3_CanoR_1	798	804	PF00244	0.351
LIG_14-3-3_CanoR_1	8	18	PF00244	0.632
LIG_14-3-3_CanoR_1	816	824	PF00244	0.546
LIG_14-3-3_CanoR_1	833	837	PF00244	0.546
LIG_14-3-3_CanoR_1	871	876	PF00244	0.522
LIG_Actin_WH2_2	1021	1039	PF00022	0.530
LIG_Actin_WH2_2	1129	1147	PF00022	0.619
LIG_Actin_WH2_2	645	663	PF00022	0.536
LIG_APCC_ABBA_1	1111	1116	PF00400	0.546
LIG_APCC_ABBA_1	889	894	PF00400	0.619
LIG_APCC_ABBAyCdc20_2	399	405	PF00400	0.599
LIG_BIR_III_2	170	174	PF00653	0.780
LIG_BIR_III_2	199	203	PF00653	0.642
LIG_BRCT_BRCA1_1	885	889	PF00533	0.549
LIG_BRCT_BRCA1_1	913	917	PF00533	0.546
LIG_Clathr_ClatBox_1	47	51	PF01394	0.752
LIG_eIF4E_1	313	319	PF01652	0.569
LIG_eIF4E_1	339	345	PF01652	0.573
LIG_FHA_1	10	16	PF00498	0.636
LIG_FHA_1	119	125	PF00498	0.751
LIG_FHA_1	136	142	PF00498	0.578
LIG_FHA_1	19	25	PF00498	0.594
LIG_FHA_1	244	250	PF00498	0.530
LIG_FHA_1	327	333	PF00498	0.539
LIG_FHA_1	346	352	PF00498	0.651
LIG_FHA_1	389	395	PF00498	0.549
LIG_FHA_1	416	422	PF00498	0.797
LIG_FHA_1	552	558	PF00498	0.649
LIG_FHA_1	791	797	PF00498	0.615
LIG_FHA_1	812	818	PF00498	0.572
LIG_FHA_1	833	839	PF00498	0.483
LIG_FHA_1	947	953	PF00498	0.546
LIG_FHA_2	1037	1043	PF00498	0.619
LIG_FHA_2	113	119	PF00498	0.650
LIG_FHA_2	38	44	PF00498	0.777
LIG_FHA_2	466	472	PF00498	0.614
LIG_FHA_2	61	67	PF00498	0.770
LIG_FHA_2	618	624	PF00498	0.596
LIG_FHA_2	644	650	PF00498	0.659
LIG_FHA_2	702	708	PF00498	0.725
LIG_FHA_2	84	90	PF00498	0.768
LIG_FHA_2	863	869	PF00498	0.620
LIG_GBD_Chelix_1	1109	1117	PF00786	0.339
LIG_GBD_Chelix_1	972	980	PF00786	0.346
LIG_LIR_Apic_2	1116	1122	PF02991	0.546
LIG_LIR_Gen_1	361	369	PF02991	0.566
LIG_LIR_Gen_1	556	567	PF02991	0.675
LIG_LIR_Gen_1	620	629	PF02991	0.584
LIG_LIR_Gen_1	870	880	PF02991	0.539
LIG_LIR_Gen_1	914	925	PF02991	0.546
LIG_LIR_Nem_3	1097	1101	PF02991	0.619
LIG_LIR_Nem_3	311	316	PF02991	0.502
LIG_LIR_Nem_3	361	365	PF02991	0.657
LIG_LIR_Nem_3	547	552	PF02991	0.642
LIG_LIR_Nem_3	556	562	PF02991	0.629
LIG_LIR_Nem_3	620	624	PF02991	0.582
LIG_LIR_Nem_3	690	696	PF02991	0.459
LIG_LIR_Nem_3	760	765	PF02991	0.607
LIG_LIR_Nem_3	870	875	PF02991	0.539
LIG_LIR_Nem_3	886	892	PF02991	0.549
LIG_LIR_Nem_3	914	920	PF02991	0.546
LIG_LYPXL_S_1	1028	1032	PF13949	0.330
LIG_LYPXL_yS_3	1029	1032	PF13949	0.546
LIG_LYPXL_yS_3	313	316	PF13949	0.575
LIG_NRBOX	318	324	PF00104	0.556
LIG_NRBOX	337	343	PF00104	0.555
LIG_NRBOX	562	568	PF00104	0.735
LIG_PCNA_PIPBox_1	897	906	PF02747	0.619
LIG_PCNA_yPIPBox_3	941	954	PF02747	0.619
LIG_PROFILIN_1	148	154	PF00235	0.596
LIG_SH2_CRK	1119	1123	PF00017	0.546
LIG_SH2_CRK	339	343	PF00017	0.560
LIG_SH2_CRK	549	553	PF00017	0.732
LIG_SH2_CRK	631	635	PF00017	0.590
LIG_SH2_CRK	693	697	PF00017	0.393
LIG_SH2_CRK	904	908	PF00017	0.546
LIG_SH2_CRK	974	978	PF00017	0.546
LIG_SH2_PTP2	559	562	PF00017	0.518
LIG_SH2_PTP2	860	863	PF00017	0.494
LIG_SH2_SRC	1101	1104	PF00017	0.546
LIG_SH2_SRC	559	562	PF00017	0.654
LIG_SH2_SRC	860	863	PF00017	0.549
LIG_SH2_STAP1	621	625	PF00017	0.582
LIG_SH2_STAT3	241	244	PF00017	0.663
LIG_SH2_STAT5	1035	1038	PF00017	0.546
LIG_SH2_STAT5	1101	1104	PF00017	0.546
LIG_SH2_STAT5	305	308	PF00017	0.564
LIG_SH2_STAT5	559	562	PF00017	0.542
LIG_SH2_STAT5	716	719	PF00017	0.665
LIG_SH2_STAT5	748	751	PF00017	0.637
LIG_SH2_STAT5	860	863	PF00017	0.549
LIG_SH2_STAT5	904	907	PF00017	0.619
LIG_SH3_1	147	153	PF00018	0.598
LIG_SH3_2	828	833	PF14604	0.619
LIG_SH3_3	1097	1103	PF00018	0.546
LIG_SH3_3	1145	1151	PF00018	0.619
LIG_SH3_3	145	151	PF00018	0.791
LIG_SH3_3	169	175	PF00018	0.800
LIG_SH3_3	23	29	PF00018	0.756
LIG_SH3_3	311	317	PF00018	0.589
LIG_SH3_3	354	360	PF00018	0.754
LIG_SH3_3	566	572	PF00018	0.726
LIG_SH3_3	574	580	PF00018	0.672
LIG_SH3_3	669	675	PF00018	0.682
LIG_SH3_3	703	709	PF00018	0.650
LIG_SH3_3	825	831	PF00018	0.619
LIG_SH3_3	858	864	PF00018	0.551
LIG_SH3_3	884	890	PF00018	0.547
LIG_SUMO_SIM_anti_2	372	377	PF11976	0.741
LIG_SUMO_SIM_anti_2	943	949	PF11976	0.556
LIG_SUMO_SIM_par_1	213	218	PF11976	0.605
LIG_SUMO_SIM_par_1	354	361	PF11976	0.656
LIG_SUMO_SIM_par_1	564	571	PF11976	0.672
LIG_SUMO_SIM_par_1	943	949	PF11976	0.546
LIG_TRAF2_1	1039	1042	PF00917	0.619
LIG_TRAF2_1	1125	1128	PF00917	0.494
LIG_TRAF2_1	115	118	PF00917	0.586
LIG_TRAF2_1	40	43	PF00917	0.772
LIG_TRAF2_1	431	434	PF00917	0.730
LIG_TRAF2_1	864	867	PF00917	0.619
LIG_TRAF2_1	933	936	PF00917	0.619
LIG_TRAF2_1	99	102	PF00917	0.765
LIG_TRFH_1	889	893	PF08558	0.513
LIG_TYR_ITIM	337	342	PF00017	0.549
LIG_TYR_ITIM	557	562	PF00017	0.654
LIG_TYR_ITIM	972	977	PF00017	0.411
LIG_WRC_WIRS_1	1044	1049	PF05994	0.436
LIG_WRC_WIRS_1	912	917	PF05994	0.411
LIG_WW_3	830	834	PF00397	0.513
MOD_CDK_SPxK_1	841	847	PF00069	0.436
MOD_CK1_1	165	171	PF00069	0.797
MOD_CK1_1	187	193	PF00069	0.729
MOD_CK1_1	276	282	PF00069	0.741
MOD_CK1_1	299	305	PF00069	0.604
MOD_CK1_1	388	394	PF00069	0.687
MOD_CK1_1	530	536	PF00069	0.761
MOD_CK1_1	588	594	PF00069	0.661
MOD_CK1_1	59	65	PF00069	0.810
MOD_CK1_1	601	607	PF00069	0.635
MOD_CK1_1	69	75	PF00069	0.700
MOD_CK1_1	789	795	PF00069	0.630
MOD_CK1_1	846	852	PF00069	0.436
MOD_CK2_1	1036	1042	PF00069	0.513
MOD_CK2_1	112	118	PF00069	0.779
MOD_CK2_1	128	134	PF00069	0.551
MOD_CK2_1	37	43	PF00069	0.785
MOD_CK2_1	422	428	PF00069	0.740
MOD_CK2_1	608	614	PF00069	0.618
MOD_CK2_1	701	707	PF00069	0.724
MOD_CK2_1	777	783	PF00069	0.724
MOD_CK2_1	83	89	PF00069	0.775
MOD_CK2_1	871	877	PF00069	0.412
MOD_Cter_Amidation	1053	1056	PF01082	0.411
MOD_GlcNHglycan	1010	1013	PF01048	0.523
MOD_GlcNHglycan	1052	1055	PF01048	0.411
MOD_GlcNHglycan	1085	1088	PF01048	0.513
MOD_GlcNHglycan	1152	1155	PF01048	0.319
MOD_GlcNHglycan	123	127	PF01048	0.801
MOD_GlcNHglycan	130	133	PF01048	0.681
MOD_GlcNHglycan	161	165	PF01048	0.758
MOD_GlcNHglycan	277	281	PF01048	0.764
MOD_GlcNHglycan	4	7	PF01048	0.764
MOD_GlcNHglycan	43	46	PF01048	0.766
MOD_GlcNHglycan	498	501	PF01048	0.731
MOD_GlcNHglycan	504	507	PF01048	0.691
MOD_GlcNHglycan	529	532	PF01048	0.744
MOD_GlcNHglycan	580	583	PF01048	0.642
MOD_GlcNHglycan	603	606	PF01048	0.726
MOD_GlcNHglycan	675	678	PF01048	0.588
MOD_GlcNHglycan	68	71	PF01048	0.784
MOD_GlcNHglycan	779	782	PF01048	0.633
MOD_GlcNHglycan	818	821	PF01048	0.474
MOD_GlcNHglycan	841	844	PF01048	0.513
MOD_GlcNHglycan	848	851	PF01048	0.348
MOD_GlcNHglycan	9	12	PF01048	0.710
MOD_GlcNHglycan	928	931	PF01048	0.411
MOD_GlcNHglycan	938	941	PF01048	0.411
MOD_GSK3_1	1050	1057	PF00069	0.411
MOD_GSK3_1	112	119	PF00069	0.798
MOD_GSK3_1	299	306	PF00069	0.624
MOD_GSK3_1	37	44	PF00069	0.804
MOD_GSK3_1	420	427	PF00069	0.750
MOD_GSK3_1	433	440	PF00069	0.720
MOD_GSK3_1	492	499	PF00069	0.686
MOD_GSK3_1	530	537	PF00069	0.737
MOD_GSK3_1	56	63	PF00069	0.527
MOD_GSK3_1	585	592	PF00069	0.723
MOD_GSK3_1	66	73	PF00069	0.783
MOD_GSK3_1	697	704	PF00069	0.637
MOD_GSK3_1	786	793	PF00069	0.714
MOD_GSK3_1	839	846	PF00069	0.417
MOD_N-GLC_1	273	278	PF02516	0.836
MOD_N-GLC_1	299	304	PF02516	0.531
MOD_N-GLC_1	496	501	PF02516	0.780
MOD_N-GLC_1	636	641	PF02516	0.584
MOD_N-GLC_1	810	815	PF02516	0.411
MOD_NEK2_1	1036	1041	PF00069	0.513
MOD_NEK2_1	1109	1114	PF00069	0.513
MOD_NEK2_1	140	145	PF00069	0.775
MOD_NEK2_1	203	208	PF00069	0.678
MOD_NEK2_1	298	303	PF00069	0.584
MOD_NEK2_1	332	337	PF00069	0.550
MOD_NEK2_1	415	420	PF00069	0.767
MOD_NEK2_1	516	521	PF00069	0.813
MOD_NEK2_1	534	539	PF00069	0.609
MOD_NEK2_1	589	594	PF00069	0.669
MOD_NEK2_2	851	856	PF00069	0.474
MOD_NEK2_2	896	901	PF00069	0.411
MOD_PIKK_1	112	118	PF00454	0.799
MOD_PIKK_1	225	231	PF00454	0.558
MOD_PIKK_1	403	409	PF00454	0.713
MOD_PK_1	685	691	PF00069	0.426
MOD_PK_1	88	94	PF00069	0.779
MOD_PK_1	954	960	PF00069	0.513
MOD_PKA_1	7	13	PF00069	0.775
MOD_PKA_2	1036	1042	PF00069	0.515
MOD_PKA_2	1054	1060	PF00069	0.238
MOD_PKA_2	1094	1100	PF00069	0.411
MOD_PKA_2	165	171	PF00069	0.783
MOD_PKA_2	225	231	PF00069	0.673
MOD_PKA_2	242	248	PF00069	0.574
MOD_PKA_2	369	375	PF00069	0.635
MOD_PKA_2	59	65	PF00069	0.776
MOD_PKA_2	66	72	PF00069	0.705
MOD_PKA_2	697	703	PF00069	0.565
MOD_PKA_2	7	13	PF00069	0.775
MOD_PKA_2	750	756	PF00069	0.628
MOD_PKA_2	777	783	PF00069	0.738
MOD_PKA_2	832	838	PF00069	0.363
MOD_PKA_2	846	852	PF00069	0.432
MOD_PKB_1	39	47	PF00069	0.753
MOD_PKB_1	525	533	PF00069	0.727
MOD_Plk_1	299	305	PF00069	0.518
MOD_Plk_1	351	357	PF00069	0.640
MOD_Plk_1	388	394	PF00069	0.529
MOD_Plk_1	636	642	PF00069	0.586
MOD_Plk_1	851	857	PF00069	0.513
MOD_Plk_2-3	352	358	PF00069	0.656
MOD_Plk_2-3	424	430	PF00069	0.754
MOD_Plk_2-3	862	868	PF00069	0.513
MOD_Plk_4	1054	1060	PF00069	0.471
MOD_Plk_4	1094	1100	PF00069	0.411
MOD_Plk_4	135	141	PF00069	0.755
MOD_Plk_4	203	209	PF00069	0.682
MOD_Plk_4	299	305	PF00069	0.557
MOD_Plk_4	352	358	PF00069	0.732
MOD_Plk_4	948	954	PF00069	0.411
MOD_ProDKin_1	118	124	PF00069	0.765
MOD_ProDKin_1	171	177	PF00069	0.795
MOD_ProDKin_1	24	30	PF00069	0.760
MOD_ProDKin_1	598	604	PF00069	0.637
MOD_ProDKin_1	608	614	PF00069	0.598
MOD_ProDKin_1	702	708	PF00069	0.711
MOD_ProDKin_1	78	84	PF00069	0.789
MOD_ProDKin_1	841	847	PF00069	0.457
TRG_DiLeu_BaEn_1	397	402	PF01217	0.658
TRG_DiLeu_BaLyEn_6	314	319	PF01217	0.561
TRG_DiLeu_BaLyEn_6	333	338	PF01217	0.545
TRG_DiLeu_BaLyEn_6	512	517	PF01217	0.727
TRG_DiLeu_BaLyEn_6	562	567	PF01217	0.735
TRG_DiLeu_BaLyEn_6	715	720	PF01217	0.566
TRG_DiLeu_BaLyEn_6	920	925	PF01217	0.513
TRG_ENDOCYTIC_2	1029	1032	PF00928	0.411
TRG_ENDOCYTIC_2	313	316	PF00928	0.575
TRG_ENDOCYTIC_2	339	342	PF00928	0.551
TRG_ENDOCYTIC_2	549	552	PF00928	0.632
TRG_ENDOCYTIC_2	559	562	PF00928	0.630
TRG_ENDOCYTIC_2	621	624	PF00928	0.588
TRG_ENDOCYTIC_2	631	634	PF00928	0.588
TRG_ENDOCYTIC_2	693	696	PF00928	0.390
TRG_ENDOCYTIC_2	716	719	PF00928	0.665
TRG_ENDOCYTIC_2	858	861	PF00928	0.353
TRG_ENDOCYTIC_2	974	977	PF00928	0.411
TRG_ER_diArg_1	1022	1024	PF00400	0.513
TRG_ER_diArg_1	1066	1068	PF00400	0.338
TRG_ER_diArg_1	192	194	PF00400	0.738
TRG_ER_diArg_1	482	485	PF00400	0.734
TRG_ER_diArg_1	514	516	PF00400	0.705
TRG_ER_diArg_1	517	520	PF00400	0.696
TRG_ER_diArg_1	522	525	PF00400	0.709
TRG_ER_diArg_1	526	528	PF00400	0.714
TRG_ER_diArg_1	755	758	PF00400	0.641
TRG_NES_CRM1_1	367	382	PF08389	0.534
TRG_NES_CRM1_1	760	775	PF08389	0.735
TRG_Pf-PMV_PEXEL_1	1070	1074	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	1135	1139	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	399	404	PF00026	0.646
TRG_Pf-PMV_PEXEL_1	484	488	PF00026	0.736
TRG_Pf-PMV_PEXEL_1	718	723	PF00026	0.656

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6B8	Leptomonas seymouri	50%	100%
A4HDE5	Leishmania braziliensis	76%	99%
A4I0S8	Leishmania infantum	98%	100%
E9AWT0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QAP4	Leishmania major	90%	100%