Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ICZ2_LEIDO

TriTrypDb:

LdBPK_180260.1 , LdCL_180007500 , LDHU3_18.0310

Length:

118


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

A0A3Q8ICZ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICZ2

PDB structure(s): 7aih_BE , 7am2_BE , 7ane_BE


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	13	15	PF00675	0.642
CLV_NRD_NRD_1	49	51	PF00675	0.404
CLV_PCSK_KEX2_1	13	15	PF00082	0.689
CLV_PCSK_KEX2_1	49	51	PF00082	0.404
DEG_Nend_Nbox_1	1	3	PF02207	0.634
DOC_CKS1_1	25	30	PF01111	0.575
DOC_MAPK_MEF2A_6	95	104	PF00069	0.377
DOC_PP1_RVXF_1	47	54	PF00149	0.394
DOC_PP4_FxxP_1	73	76	PF00568	0.446
DOC_WW_Pin1_4	107	112	PF00397	0.356
DOC_WW_Pin1_4	19	24	PF00397	0.572
LIG_14-3-3_CanoR_1	13	17	PF00244	0.636
LIG_14-3-3_CanoR_1	30	35	PF00244	0.448
LIG_14-3-3_CanoR_1	49	54	PF00244	0.390
LIG_LIR_Apic_2	71	76	PF02991	0.434
LIG_REV1ctd_RIR_1	37	46	PF16727	0.414
LIG_SH2_STAT5	103	106	PF00017	0.327
LIG_SH2_STAT5	86	89	PF00017	0.464
LIG_SH3_3	17	23	PF00018	0.477
MOD_CDK_SPxK_1	24	30	PF00069	0.576
MOD_CK1_1	33	39	PF00069	0.429
MOD_CK1_1	80	86	PF00069	0.502
MOD_CK2_1	112	118	PF00069	0.405
MOD_GSK3_1	26	33	PF00069	0.551
MOD_LATS_1	47	53	PF00433	0.396
MOD_N-GLC_1	107	112	PF02516	0.356
MOD_NEK2_1	68	73	PF00069	0.394
MOD_PK_1	30	36	PF00069	0.443
MOD_PKA_1	49	55	PF00069	0.392
MOD_PKA_2	12	18	PF00069	0.672
MOD_PKA_2	49	55	PF00069	0.392
MOD_ProDKin_1	107	113	PF00069	0.353
MOD_ProDKin_1	19	25	PF00069	0.572
TRG_ER_diArg_1	49	51	PF00400	0.428


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHE6	Leptomonas seymouri	91%	91%
A0A1X0P6R5	Trypanosomatidae	72%	100%
A0A3S5IS44	Trypanosoma rangeli	76%	100%
A4H9D0	Leishmania braziliensis	94%	100%
A4HXQ2	Leishmania infantum	100%	100%
B6DTE3	Bodo saltans	74%	100%
D0A030	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	100%
E9ARG3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4QE16	Leishmania major	98%	100%