LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

RNA-binding protein, putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RNA-binding protein, putative
Gene product:
RNA-binding protein, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8ICU3_LEIDO
TriTrypDb:
LdCL_170015000 , LDHU3_17.1310
Length:
379

Annotations

LeishMANIAdb annotations

A Kinetoplastid-specific protein. Unlikely to be a membrane protein.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICU3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICU3

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 3
GO:0005488 binding 1 3
GO:0097159 organic cyclic compound binding 2 3
GO:1901363 heterocyclic compound binding 2 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 17 21 PF00656 0.469
CLV_C14_Caspase3-7 188 192 PF00656 0.438
CLV_C14_Caspase3-7 262 266 PF00656 0.567
CLV_NRD_NRD_1 10 12 PF00675 0.483
CLV_NRD_NRD_1 182 184 PF00675 0.605
CLV_NRD_NRD_1 277 279 PF00675 0.585
CLV_NRD_NRD_1 52 54 PF00675 0.614
CLV_PCSK_KEX2_1 10 12 PF00082 0.491
CLV_PCSK_KEX2_1 182 184 PF00082 0.598
CLV_PCSK_KEX2_1 52 54 PF00082 0.614
CLV_PCSK_SKI1_1 183 187 PF00082 0.527
CLV_PCSK_SKI1_1 278 282 PF00082 0.484
DEG_Nend_UBRbox_3 1 3 PF02207 0.508
DOC_MAPK_MEF2A_6 204 212 PF00069 0.487
DOC_USP7_MATH_1 112 116 PF00917 0.619
DOC_USP7_MATH_1 353 357 PF00917 0.417
DOC_USP7_MATH_1 371 375 PF00917 0.626
DOC_USP7_MATH_1 64 68 PF00917 0.699
DOC_USP7_MATH_1 88 92 PF00917 0.661
DOC_USP7_MATH_2 166 172 PF00917 0.480
DOC_USP7_UBL2_3 279 283 PF12436 0.612
DOC_WW_Pin1_4 166 171 PF00397 0.503
DOC_WW_Pin1_4 263 268 PF00397 0.710
DOC_WW_Pin1_4 342 347 PF00397 0.486
DOC_WW_Pin1_4 84 89 PF00397 0.676
LIG_14-3-3_CanoR_1 173 177 PF00244 0.512
LIG_14-3-3_CanoR_1 197 205 PF00244 0.372
LIG_14-3-3_CanoR_1 241 249 PF00244 0.565
LIG_14-3-3_CanoR_1 41 47 PF00244 0.490
LIG_Actin_WH2_2 323 341 PF00022 0.482
LIG_BIR_III_4 191 195 PF00653 0.487
LIG_BRCT_BRCA1_1 373 377 PF00533 0.372
LIG_BRCT_BRCA1_2 373 379 PF00533 0.388
LIG_CtBP_PxDLS_1 209 213 PF00389 0.503
LIG_FHA_1 132 138 PF00498 0.470
LIG_FHA_1 241 247 PF00498 0.615
LIG_FHA_1 311 317 PF00498 0.496
LIG_FHA_1 41 47 PF00498 0.498
LIG_FHA_1 7 13 PF00498 0.466
LIG_FHA_2 186 192 PF00498 0.428
LIG_FHA_2 339 345 PF00498 0.461
LIG_Integrin_RGD_1 302 304 PF01839 0.640
LIG_PTB_Apo_2 331 338 PF02174 0.351
LIG_PTB_Phospho_1 331 337 PF10480 0.353
LIG_SH2_STAT5 275 278 PF00017 0.624
LIG_SH2_STAT5 337 340 PF00017 0.538
LIG_SH3_3 261 267 PF00018 0.532
LIG_SH3_3 347 353 PF00018 0.402
LIG_SUMO_SIM_anti_2 121 127 PF11976 0.337
LIG_SUMO_SIM_anti_2 315 322 PF11976 0.363
LIG_SUMO_SIM_anti_2 4 9 PF11976 0.468
LIG_SUMO_SIM_par_1 347 352 PF11976 0.379
LIG_SUMO_SIM_par_1 4 9 PF11976 0.490
LIG_TRAF2_1 259 262 PF00917 0.595
LIG_WRC_WIRS_1 186 191 PF05994 0.424
MOD_CDK_SPxxK_3 166 173 PF00069 0.441
MOD_CK1_1 169 175 PF00069 0.480
MOD_CK1_1 242 248 PF00069 0.542
MOD_CK1_1 282 288 PF00069 0.593
MOD_CK2_1 29 35 PF00069 0.567
MOD_CK2_1 338 344 PF00069 0.448
MOD_GlcNHglycan 115 118 PF01048 0.519
MOD_GlcNHglycan 152 155 PF01048 0.592
MOD_GlcNHglycan 290 293 PF01048 0.646
MOD_GlcNHglycan 321 324 PF01048 0.492
MOD_GlcNHglycan 355 358 PF01048 0.472
MOD_GlcNHglycan 66 69 PF01048 0.655
MOD_GSK3_1 14 21 PF00069 0.433
MOD_GSK3_1 160 167 PF00069 0.522
MOD_GSK3_1 168 175 PF00069 0.496
MOD_GSK3_1 193 200 PF00069 0.411
MOD_GSK3_1 274 281 PF00069 0.708
MOD_GSK3_1 284 291 PF00069 0.607
MOD_GSK3_1 338 345 PF00069 0.593
MOD_GSK3_1 371 378 PF00069 0.579
MOD_GSK3_1 58 65 PF00069 0.622
MOD_GSK3_1 84 91 PF00069 0.604
MOD_NEK2_1 150 155 PF00069 0.651
MOD_NEK2_1 6 11 PF00069 0.471
MOD_NEK2_1 81 86 PF00069 0.624
MOD_PIKK_1 197 203 PF00454 0.356
MOD_PIKK_1 371 377 PF00454 0.528
MOD_PKA_1 278 284 PF00069 0.485
MOD_PKA_2 172 178 PF00069 0.480
MOD_PKA_2 196 202 PF00069 0.439
MOD_PKA_2 240 246 PF00069 0.657
MOD_PKA_2 338 344 PF00069 0.555
MOD_PKA_2 40 46 PF00069 0.566
MOD_Plk_4 121 127 PF00069 0.602
MOD_Plk_4 160 166 PF00069 0.630
MOD_Plk_4 172 178 PF00069 0.486
MOD_ProDKin_1 166 172 PF00069 0.493
MOD_ProDKin_1 263 269 PF00069 0.711
MOD_ProDKin_1 342 348 PF00069 0.473
MOD_ProDKin_1 84 90 PF00069 0.676
TRG_ER_diArg_1 10 12 PF00400 0.490
TRG_ER_diArg_1 182 184 PF00400 0.605
TRG_Pf-PMV_PEXEL_1 218 223 PF00026 0.425
TRG_Pf-PMV_PEXEL_1 31 35 PF00026 0.527

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKU0 Leptomonas seymouri 42% 73%
A0A1X0NT51 Trypanosomatidae 27% 76%
A0A3R7JY32 Trypanosoma rangeli 27% 83%
A4H944 Leishmania braziliensis 79% 100%
C9ZP32 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 82%
E9AR53 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4QEB0 Leishmania major 93% 100%
V5B6D3 Trypanosoma cruzi 29% 80%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS