Transcription initiation factor TFIID subunit 8

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ICR8_LEIDO

TriTrypDb:

LdBPK_120870.1 , LdCL_120020800 , LDHU3_12.1670

Length:

213

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized LINJ.12.0870

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICR8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICR8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	201	203	PF00675	0.516
CLV_PCSK_FUR_1	199	203	PF00082	0.497
CLV_PCSK_KEX2_1	199	201	PF00082	0.508
CLV_PCSK_KEX2_1	204	206	PF00082	0.527
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.587
CLV_PCSK_PC7_1	200	206	PF00082	0.511
CLV_PCSK_SKI1_1	174	178	PF00082	0.555
CLV_PCSK_SKI1_1	60	64	PF00082	0.602
CLV_Separin_Metazoa	196	200	PF03568	0.417
DEG_APCC_DBOX_1	59	67	PF00400	0.512
DEG_Nend_UBRbox_2	1	3	PF02207	0.681
DOC_PP1_RVXF_1	92	98	PF00149	0.443
DOC_PP4_FxxP_1	143	146	PF00568	0.613
DOC_USP7_MATH_1	78	82	PF00917	0.566
DOC_USP7_UBL2_3	8	12	PF12436	0.531
LIG_14-3-3_CanoR_1	94	98	PF00244	0.543
LIG_Actin_WH2_2	93	108	PF00022	0.424
LIG_AP2alpha_2	51	53	PF02296	0.570
LIG_EVH1_2	127	131	PF00568	0.548
LIG_FHA_1	127	133	PF00498	0.547
LIG_FHA_1	142	148	PF00498	0.618
LIG_FHA_1	176	182	PF00498	0.519
LIG_Integrin_isoDGR_2	137	139	PF01839	0.478
LIG_Integrin_RGD_1	160	162	PF01839	0.557
LIG_LIR_Apic_2	123	127	PF02991	0.507
LIG_LIR_Gen_1	96	105	PF02991	0.519
LIG_LIR_Nem_3	96	100	PF02991	0.565
LIG_SH2_STAT5	121	124	PF00017	0.530
LIG_SH3_3	129	135	PF00018	0.493
LIG_SH3_3	20	26	PF00018	0.557
LIG_SH3_3	61	67	PF00018	0.634
LIG_SH3_5	117	121	PF00018	0.548
LIG_TRAF2_1	107	110	PF00917	0.530
MOD_CK1_1	170	176	PF00069	0.470
MOD_CK1_1	192	198	PF00069	0.408
MOD_GlcNHglycan	27	30	PF01048	0.649
MOD_GlcNHglycan	80	83	PF01048	0.667
MOD_NEK2_1	189	194	PF00069	0.574
MOD_PKA_1	200	206	PF00069	0.579
MOD_PKA_2	189	195	PF00069	0.544
MOD_PKA_2	200	206	PF00069	0.466
MOD_PKA_2	93	99	PF00069	0.565
MOD_Plk_4	19	25	PF00069	0.511
MOD_SUMO_for_1	6	9	PF00179	0.553
MOD_SUMO_rev_2	43	52	PF00179	0.593
TRG_DiLeu_BaEn_1	164	169	PF01217	0.520
TRG_ER_diArg_1	152	155	PF00400	0.581
TRG_ER_diArg_1	198	201	PF00400	0.566
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILD1	Leptomonas seymouri	48%	95%
E9AGJ1	Leishmania infantum	100%	100%
E9AIN7	Leishmania braziliensis	72%	100%
E9AP29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	98%
Q4QGG0	Leishmania major	86%	100%