Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8ICM6_LEIDO

TriTrypDb:

LdCL_230022400 , LDHU3_23.2040

Length:

306

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3Q8ICM6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICM6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.387
CLV_NRD_NRD_1	85	87	PF00675	0.349
CLV_PCSK_KEX2_1	67	69	PF00082	0.309
CLV_PCSK_KEX2_1	85	87	PF00082	0.349
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.309
DOC_CKS1_1	162	167	PF01111	0.582
DOC_CYCLIN_yCln2_LP_2	198	201	PF00134	0.596
DOC_PP2B_LxvP_1	197	200	PF13499	0.605
DOC_PP2B_LxvP_1	258	261	PF13499	0.606
DOC_PP4_FxxP_1	177	180	PF00568	0.624
DOC_USP7_MATH_1	119	123	PF00917	0.558
DOC_USP7_MATH_1	183	187	PF00917	0.611
DOC_USP7_MATH_1	282	286	PF00917	0.601
DOC_USP7_MATH_1	298	302	PF00917	0.579
DOC_USP7_MATH_2	98	104	PF00917	0.594
DOC_USP7_UBL2_3	76	80	PF12436	0.509
DOC_WW_Pin1_4	109	114	PF00397	0.584
DOC_WW_Pin1_4	117	122	PF00397	0.564
DOC_WW_Pin1_4	142	147	PF00397	0.598
DOC_WW_Pin1_4	161	166	PF00397	0.584
DOC_WW_Pin1_4	176	181	PF00397	0.625
DOC_WW_Pin1_4	189	194	PF00397	0.604
DOC_WW_Pin1_4	199	204	PF00397	0.597
DOC_WW_Pin1_4	217	222	PF00397	0.613
DOC_WW_Pin1_4	296	301	PF00397	0.586
LIG_14-3-3_CanoR_1	156	161	PF00244	0.606
LIG_14-3-3_CanoR_1	174	180	PF00244	0.625
LIG_14-3-3_CanoR_1	191	197	PF00244	0.601
LIG_14-3-3_CanoR_1	226	230	PF00244	0.613
LIG_14-3-3_CanoR_1	237	242	PF00244	0.612
LIG_BRCT_BRCA1_1	219	223	PF00533	0.610
LIG_BRCT_BRCA1_1	300	304	PF00533	0.576
LIG_Clathr_ClatBox_1	3	7	PF01394	0.553
LIG_CSL_BTD_1	95	98	PF09270	0.596
LIG_EVH1_1	258	262	PF00568	0.605
LIG_FHA_1	43	49	PF00498	0.199
LIG_FHA_2	211	217	PF00498	0.631
LIG_LIR_Apic_2	136	141	PF02991	0.579
LIG_LIR_Apic_2	175	180	PF02991	0.624
LIG_LIR_Gen_1	271	280	PF02991	0.598
LIG_LIR_Nem_3	271	275	PF02991	0.595
LIG_MYND_1	95	99	PF01753	0.596
LIG_PROFILIN_1	165	171	PF00235	0.587
LIG_RPA_C_Fungi	283	295	PF08784	0.487
LIG_SH2_CRK	138	142	PF00017	0.460
LIG_SH2_CRK	158	162	PF00017	0.483
LIG_SH2_CRK	44	48	PF00017	0.199
LIG_SH2_NCK_1	138	142	PF00017	0.460
LIG_SH2_NCK_1	158	162	PF00017	0.483
LIG_SH2_SRC	16	19	PF00017	0.199
LIG_SH2_STAT5	130	133	PF00017	0.439
LIG_SH2_STAT5	158	161	PF00017	0.489
LIG_SH2_STAT5	16	19	PF00017	0.199
LIG_SH2_STAT5	293	296	PF00017	0.489
LIG_SH2_STAT5	44	47	PF00017	0.199
LIG_SH3_1	138	144	PF00018	0.467
LIG_SH3_3	107	113	PF00018	0.457
LIG_SH3_3	138	144	PF00018	0.467
LIG_SH3_3	157	163	PF00018	0.482
LIG_SH3_3	164	170	PF00018	0.455
LIG_SH3_3	177	183	PF00018	0.511
LIG_SH3_3	197	203	PF00018	0.478
LIG_SH3_3	256	262	PF00018	0.491
LIG_SH3_3	27	33	PF00018	0.199
LIG_SH3_3	85	91	PF00018	0.417
LIG_SH3_3	92	98	PF00018	0.464
LIG_SUMO_SIM_anti_2	195	200	PF11976	0.485
LIG_SUMO_SIM_anti_2	20	27	PF11976	0.199
LIG_TRAF2_2	205	210	PF00917	0.511
MOD_CDK_SPK_2	176	181	PF00069	0.515
MOD_CK1_1	123	129	PF00069	0.430
MOD_CK1_1	142	148	PF00069	0.477
MOD_CK1_1	175	181	PF00069	0.515
MOD_CK1_1	192	198	PF00069	0.480
MOD_CK1_1	228	234	PF00069	0.494
MOD_CK1_1	271	277	PF00069	0.474
MOD_CK1_1	296	302	PF00069	0.458
MOD_Cter_Amidation	104	107	PF01082	0.463
MOD_DYRK1A_RPxSP_1	181	185	PF00069	0.501
MOD_GlcNHglycan	122	125	PF01048	0.418
MOD_GlcNHglycan	135	138	PF01048	0.438
MOD_GlcNHglycan	185	188	PF01048	0.480
MOD_GlcNHglycan	234	237	PF01048	0.484
MOD_GlcNHglycan	295	298	PF01048	0.478
MOD_GlcNHglycan	38	41	PF01048	0.360
MOD_GSK3_1	119	126	PF00069	0.424
MOD_GSK3_1	169	176	PF00069	0.501
MOD_GSK3_1	179	186	PF00069	0.503
MOD_GSK3_1	217	224	PF00069	0.499
MOD_GSK3_1	228	235	PF00069	0.492
MOD_GSK3_1	284	291	PF00069	0.486
MOD_GSK3_1	299	306	PF00069	0.456
MOD_N-GLC_1	217	222	PF02516	0.498
MOD_N-GLC_1	282	287	PF02516	0.481
MOD_NEK2_1	173	178	PF00069	0.518
MOD_NEK2_1	232	237	PF00069	0.486
MOD_NEK2_1	254	259	PF00069	0.500
MOD_PIKK_1	89	95	PF00454	0.442
MOD_PK_1	237	243	PF00069	0.498
MOD_PKA_2	173	179	PF00069	0.517
MOD_PKA_2	225	231	PF00069	0.497
MOD_PKA_2	236	242	PF00069	0.494
MOD_PKB_1	286	294	PF00069	0.489
MOD_Plk_1	210	216	PF00069	0.523
MOD_Plk_2-3	210	216	PF00069	0.523
MOD_Plk_4	18	24	PF00069	0.199
MOD_Plk_4	192	198	PF00069	0.480
MOD_Plk_4	210	216	PF00069	0.523
MOD_Plk_4	299	305	PF00069	0.450
MOD_ProDKin_1	109	115	PF00069	0.460
MOD_ProDKin_1	117	123	PF00069	0.427
MOD_ProDKin_1	142	148	PF00069	0.477
MOD_ProDKin_1	161	167	PF00069	0.456
MOD_ProDKin_1	176	182	PF00069	0.513
MOD_ProDKin_1	189	195	PF00069	0.484
MOD_ProDKin_1	199	205	PF00069	0.478
MOD_ProDKin_1	217	223	PF00069	0.500
MOD_ProDKin_1	296	302	PF00069	0.458
MOD_SUMO_rev_2	271	280	PF00179	0.477
TRG_ENDOCYTIC_2	16	19	PF00928	0.199
TRG_ENDOCYTIC_2	272	275	PF00928	0.473
TRG_ENDOCYTIC_2	44	47	PF00928	0.199
TRG_ER_diArg_1	85	87	PF00400	0.408
TRG_Pf-PMV_PEXEL_1	15	20	PF00026	0.199