Exonuclease 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Exonuclease 1

Gene product:

XPG N-terminal domain/XPG I-region, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8ICM3_LEIDO

TriTrypDb:

LdBPK_231530.1 , LdCL_230022500 , LDHU3_23.2050

Length:

1015

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

A0A3Q8ICM3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICM3

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003677	DNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0004518	nuclease activity	4	7
GO:0004527	exonuclease activity	5	7
GO:0004529	DNA exonuclease activity	5	7
GO:0004536	DNA nuclease activity	4	7
GO:0005488	binding	1	7
GO:0008409	5'-3' exonuclease activity	6	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	7
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6	7
GO:0035312	5'-3' DNA exonuclease activity	7	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:1901363	heterocyclic compound binding	2	7
GO:0004519	endonuclease activity	5	1
GO:0004520	DNA endonuclease activity	5	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0017108	5'-flap endonuclease activity	7	1
GO:0048256	flap endonuclease activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	613	617	PF00656	0.677
CLV_C14_Caspase3-7	65	69	PF00656	0.614
CLV_C14_Caspase3-7	681	685	PF00656	0.541
CLV_C14_Caspase3-7	754	758	PF00656	0.633
CLV_NRD_NRD_1	139	141	PF00675	0.285
CLV_NRD_NRD_1	161	163	PF00675	0.490
CLV_NRD_NRD_1	280	282	PF00675	0.497
CLV_NRD_NRD_1	304	306	PF00675	0.676
CLV_NRD_NRD_1	316	318	PF00675	0.592
CLV_NRD_NRD_1	423	425	PF00675	0.430
CLV_NRD_NRD_1	513	515	PF00675	0.487
CLV_NRD_NRD_1	541	543	PF00675	0.645
CLV_NRD_NRD_1	784	786	PF00675	0.575
CLV_PCSK_FUR_1	136	140	PF00082	0.282
CLV_PCSK_FUR_1	511	515	PF00082	0.466
CLV_PCSK_KEX2_1	138	140	PF00082	0.275
CLV_PCSK_KEX2_1	160	162	PF00082	0.475
CLV_PCSK_KEX2_1	280	282	PF00082	0.497
CLV_PCSK_KEX2_1	304	306	PF00082	0.676
CLV_PCSK_KEX2_1	316	318	PF00082	0.598
CLV_PCSK_KEX2_1	423	425	PF00082	0.425
CLV_PCSK_KEX2_1	513	515	PF00082	0.487
CLV_PCSK_KEX2_1	541	543	PF00082	0.645
CLV_PCSK_SKI1_1	1009	1013	PF00082	0.608
CLV_PCSK_SKI1_1	298	302	PF00082	0.627
CLV_PCSK_SKI1_1	392	396	PF00082	0.388
DEG_APCC_DBOX_1	780	788	PF00400	0.572
DEG_SPOP_SBC_1	578	582	PF00917	0.687
DOC_CDC14_PxL_1	969	977	PF14671	0.618
DOC_CYCLIN_RxL_1	1003	1015	PF00134	0.607
DOC_CYCLIN_yCln2_LP_2	269	275	PF00134	0.461
DOC_MAPK_DCC_7	112	120	PF00069	0.475
DOC_MAPK_FxFP_2	415	418	PF00069	0.487
DOC_MAPK_gen_1	23	33	PF00069	0.475
DOC_MAPK_gen_1	44	53	PF00069	0.465
DOC_MAPK_MEF2A_6	112	120	PF00069	0.529
DOC_MAPK_MEF2A_6	23	31	PF00069	0.475
DOC_PP2B_LxvP_1	269	272	PF13499	0.452
DOC_PP2B_LxvP_1	273	276	PF13499	0.433
DOC_PP2B_LxvP_1	975	978	PF13499	0.561
DOC_PP4_FxxP_1	415	418	PF00568	0.487
DOC_PP4_FxxP_1	557	560	PF00568	0.602
DOC_PP4_FxxP_1	915	918	PF00568	0.606
DOC_SPAK_OSR1_1	112	116	PF12202	0.475
DOC_USP7_MATH_1	178	182	PF00917	0.440
DOC_USP7_MATH_1	239	243	PF00917	0.475
DOC_USP7_MATH_1	283	287	PF00917	0.443
DOC_USP7_MATH_1	331	335	PF00917	0.721
DOC_USP7_MATH_1	338	342	PF00917	0.668
DOC_USP7_MATH_1	361	365	PF00917	0.510
DOC_USP7_MATH_1	454	458	PF00917	0.625
DOC_USP7_MATH_1	578	582	PF00917	0.687
DOC_USP7_MATH_1	674	678	PF00917	0.614
DOC_USP7_MATH_1	738	742	PF00917	0.643
DOC_USP7_MATH_1	879	883	PF00917	0.773
DOC_USP7_MATH_1	922	926	PF00917	0.581
DOC_USP7_MATH_1	968	972	PF00917	0.627
DOC_USP7_MATH_1	994	998	PF00917	0.647
DOC_USP7_UBL2_3	1009	1013	PF12436	0.580
DOC_USP7_UBL2_3	392	396	PF12436	0.388
DOC_WW_Pin1_4	440	445	PF00397	0.426
DOC_WW_Pin1_4	548	553	PF00397	0.642
DOC_WW_Pin1_4	58	63	PF00397	0.492
DOC_WW_Pin1_4	661	666	PF00397	0.584
DOC_WW_Pin1_4	711	716	PF00397	0.721
DOC_WW_Pin1_4	78	83	PF00397	0.652
DOC_WW_Pin1_4	887	892	PF00397	0.637
DOC_WW_Pin1_4	898	903	PF00397	0.585
DOC_WW_Pin1_4	932	937	PF00397	0.704
DOC_WW_Pin1_4	954	959	PF00397	0.600
DOC_WW_Pin1_4	977	982	PF00397	0.606
DOC_WW_Pin1_4	996	1001	PF00397	0.612
LIG_14-3-3_CanoR_1	174	178	PF00244	0.553
LIG_14-3-3_CanoR_1	328	335	PF00244	0.612
LIG_14-3-3_CanoR_1	405	415	PF00244	0.474
LIG_14-3-3_CanoR_1	44	53	PF00244	0.465
LIG_14-3-3_CanoR_1	513	522	PF00244	0.527
LIG_14-3-3_CanoR_1	601	610	PF00244	0.599
LIG_14-3-3_CanoR_1	635	639	PF00244	0.657
LIG_14-3-3_CanoR_1	654	659	PF00244	0.628
LIG_14-3-3_CanoR_1	839	844	PF00244	0.494
LIG_14-3-3_CanoR_1	986	995	PF00244	0.572
LIG_APCC_ABBA_1	533	538	PF00400	0.672
LIG_APCC_ABBAyCdc20_2	532	538	PF00400	0.673
LIG_BRCT_BRCA1_1	594	598	PF00533	0.598
LIG_CaM_IQ_9	506	522	PF13499	0.484
LIG_Clathr_ClatBox_1	148	152	PF01394	0.399
LIG_FHA_1	444	450	PF00498	0.505
LIG_FHA_1	45	51	PF00498	0.381
LIG_FHA_1	461	467	PF00498	0.494
LIG_FHA_1	491	497	PF00498	0.418
LIG_FHA_1	504	510	PF00498	0.403
LIG_FHA_1	689	695	PF00498	0.646
LIG_FHA_1	798	804	PF00498	0.633
LIG_FHA_1	964	970	PF00498	0.609
LIG_FHA_1	99	105	PF00498	0.512
LIG_FHA_2	1003	1009	PF00498	0.529
LIG_FHA_2	130	136	PF00498	0.475
LIG_FHA_2	407	413	PF00498	0.387
LIG_FHA_2	63	69	PF00498	0.607
LIG_FHA_2	699	705	PF00498	0.634
LIG_FHA_2	759	765	PF00498	0.576
LIG_FHA_2	980	986	PF00498	0.581
LIG_LIR_Apic_2	412	418	PF02991	0.418
LIG_LIR_Apic_2	556	560	PF02991	0.608
LIG_LIR_Gen_1	1005	1012	PF02991	0.509
LIG_LIR_Gen_1	30	39	PF02991	0.475
LIG_LIR_Gen_1	367	376	PF02991	0.350
LIG_LIR_Gen_1	523	533	PF02991	0.597
LIG_LIR_Gen_1	729	740	PF02991	0.598
LIG_LIR_Nem_3	30	35	PF02991	0.475
LIG_LIR_Nem_3	367	371	PF02991	0.365
LIG_LIR_Nem_3	431	436	PF02991	0.390
LIG_LIR_Nem_3	451	455	PF02991	0.493
LIG_LIR_Nem_3	595	600	PF02991	0.663
LIG_LIR_Nem_3	729	735	PF02991	0.603
LIG_LYPXL_SIV_4	183	191	PF13949	0.451
LIG_MLH1_MIPbox_1	594	598	PF16413	0.598
LIG_MYND_1	864	868	PF01753	0.612
LIG_PCNA_PIPBox_1	502	511	PF02747	0.410
LIG_PCNA_yPIPBox_3	498	509	PF02747	0.411
LIG_Pex14_2	844	848	PF04695	0.480
LIG_PROFILIN_1	859	865	PF00235	0.612
LIG_REV1ctd_RIR_1	276	285	PF16727	0.412
LIG_REV1ctd_RIR_1	51	61	PF16727	0.518
LIG_REV1ctd_RIR_1	595	605	PF16727	0.662
LIG_SH2_CRK	442	446	PF00017	0.370
LIG_SH2_CRK	452	456	PF00017	0.423
LIG_SH2_CRK	497	501	PF00017	0.412
LIG_SH2_NCK_1	801	805	PF00017	0.649
LIG_SH2_PTP2	32	35	PF00017	0.475
LIG_SH2_SRC	184	187	PF00017	0.397
LIG_SH2_STAP1	184	188	PF00017	0.396
LIG_SH2_STAP1	222	226	PF00017	0.475
LIG_SH2_STAP1	368	372	PF00017	0.356
LIG_SH2_STAT5	13	16	PF00017	0.475
LIG_SH2_STAT5	155	158	PF00017	0.371
LIG_SH2_STAT5	164	167	PF00017	0.552
LIG_SH2_STAT5	230	233	PF00017	0.475
LIG_SH2_STAT5	236	239	PF00017	0.486
LIG_SH2_STAT5	251	254	PF00017	0.548
LIG_SH2_STAT5	32	35	PF00017	0.475
LIG_SH2_STAT5	382	385	PF00017	0.407
LIG_SH2_STAT5	434	437	PF00017	0.349
LIG_SH2_STAT5	508	511	PF00017	0.416
LIG_SH2_STAT5	522	525	PF00017	0.548
LIG_SH2_STAT5	910	913	PF00017	0.612
LIG_SH3_3	265	271	PF00018	0.518
LIG_SH3_3	438	444	PF00018	0.338
LIG_SH3_3	497	503	PF00018	0.598
LIG_SH3_3	637	643	PF00018	0.688
LIG_SH3_3	659	665	PF00018	0.619
LIG_SH3_3	820	826	PF00018	0.669
LIG_SH3_3	856	862	PF00018	0.620
LIG_SH3_3	865	871	PF00018	0.624
LIG_SH3_3	888	894	PF00018	0.644
LIG_SH3_3	933	939	PF00018	0.647
LIG_SH3_3	975	981	PF00018	0.653
LIG_SH3_3	990	996	PF00018	0.637
LIG_Sin3_3	293	300	PF02671	0.569
LIG_SUMO_SIM_anti_2	90	97	PF11976	0.470
LIG_SUMO_SIM_par_1	90	97	PF11976	0.383
LIG_TRAF2_1	132	135	PF00917	0.475
LIG_TRAF2_1	183	186	PF00917	0.465
LIG_TYR_ITIM	440	445	PF00017	0.350
LIG_TYR_ITIM	450	455	PF00017	0.414
LIG_UBA3_1	1006	1014	PF00899	0.657
LIG_WRC_WIRS_1	259	264	PF05994	0.475
LIG_WRC_WIRS_1	368	373	PF05994	0.393
LIG_WW_2	864	867	PF00397	0.611
LIG_WW_2	993	996	PF00397	0.624
LIG_WW_3	824	828	PF00397	0.657
LIG_WW_3	916	920	PF00397	0.602
MOD_CDC14_SPxK_1	551	554	PF00782	0.634
MOD_CDC14_SPxK_1	957	960	PF00782	0.539
MOD_CDK_SPxK_1	548	554	PF00069	0.641
MOD_CDK_SPxK_1	954	960	PF00069	0.561
MOD_CDK_SPxxK_3	890	897	PF00069	0.705
MOD_CDK_SPxxK_3	898	905	PF00069	0.602
MOD_CDK_SPxxK_3	996	1003	PF00069	0.545
MOD_CK1_1	242	248	PF00069	0.475
MOD_CK1_1	364	370	PF00069	0.464
MOD_CK1_1	443	449	PF00069	0.465
MOD_CK1_1	457	463	PF00069	0.362
MOD_CK1_1	545	551	PF00069	0.621
MOD_CK1_1	580	586	PF00069	0.628
MOD_CK1_1	664	670	PF00069	0.597
MOD_CK1_1	741	747	PF00069	0.577
MOD_CK1_1	751	757	PF00069	0.620
MOD_CK1_1	758	764	PF00069	0.722
MOD_CK1_1	890	896	PF00069	0.630
MOD_CK1_1	898	904	PF00069	0.581
MOD_CK1_1	932	938	PF00069	0.690
MOD_CK1_1	971	977	PF00069	0.642
MOD_CK1_1	979	985	PF00069	0.698
MOD_CK2_1	1002	1008	PF00069	0.532
MOD_CK2_1	128	134	PF00069	0.476
MOD_CK2_1	406	412	PF00069	0.382
MOD_CK2_1	60	66	PF00069	0.519
MOD_CK2_1	608	614	PF00069	0.619
MOD_CK2_1	698	704	PF00069	0.740
MOD_CK2_1	758	764	PF00069	0.571
MOD_CK2_1	839	845	PF00069	0.497
MOD_CK2_1	851	857	PF00069	0.584
MOD_CK2_1	956	962	PF00069	0.637
MOD_DYRK1A_RPxSP_1	661	665	PF00069	0.676
MOD_GlcNHglycan	107	110	PF01048	0.312
MOD_GlcNHglycan	237	240	PF01048	0.234
MOD_GlcNHglycan	262	265	PF01048	0.275
MOD_GlcNHglycan	285	288	PF01048	0.534
MOD_GlcNHglycan	290	293	PF01048	0.558
MOD_GlcNHglycan	298	301	PF01048	0.559
MOD_GlcNHglycan	321	324	PF01048	0.595
MOD_GlcNHglycan	329	332	PF01048	0.616
MOD_GlcNHglycan	355	358	PF01048	0.654
MOD_GlcNHglycan	363	366	PF01048	0.632
MOD_GlcNHglycan	377	380	PF01048	0.261
MOD_GlcNHglycan	459	462	PF01048	0.518
MOD_GlcNHglycan	543	547	PF01048	0.627
MOD_GlcNHglycan	567	570	PF01048	0.593
MOD_GlcNHglycan	573	576	PF01048	0.608
MOD_GlcNHglycan	616	619	PF01048	0.641
MOD_GlcNHglycan	622	625	PF01048	0.719
MOD_GlcNHglycan	674	677	PF01048	0.679
MOD_GlcNHglycan	680	684	PF01048	0.635
MOD_GlcNHglycan	738	741	PF01048	0.657
MOD_GlcNHglycan	877	880	PF01048	0.721
MOD_GlcNHglycan	897	900	PF01048	0.674
MOD_GlcNHglycan	907	910	PF01048	0.590
MOD_GlcNHglycan	924	927	PF01048	0.711
MOD_GlcNHglycan	929	932	PF01048	0.697
MOD_GlcNHglycan	988	991	PF01048	0.625
MOD_GSK3_1	235	242	PF00069	0.592
MOD_GSK3_1	254	261	PF00069	0.467
MOD_GSK3_1	283	290	PF00069	0.514
MOD_GSK3_1	327	334	PF00069	0.611
MOD_GSK3_1	351	358	PF00069	0.705
MOD_GSK3_1	56	63	PF00069	0.509
MOD_GSK3_1	577	584	PF00069	0.627
MOD_GSK3_1	608	615	PF00069	0.669
MOD_GSK3_1	642	649	PF00069	0.667
MOD_GSK3_1	660	667	PF00069	0.572
MOD_GSK3_1	668	675	PF00069	0.633
MOD_GSK3_1	690	697	PF00069	0.651
MOD_GSK3_1	741	748	PF00069	0.566
MOD_GSK3_1	751	758	PF00069	0.664
MOD_GSK3_1	813	820	PF00069	0.701
MOD_GSK3_1	839	846	PF00069	0.496
MOD_GSK3_1	875	882	PF00069	0.775
MOD_GSK3_1	886	893	PF00069	0.615
MOD_GSK3_1	918	925	PF00069	0.611
MOD_GSK3_1	963	970	PF00069	0.668
MOD_LATS_1	652	658	PF00433	0.570
MOD_N-GLC_1	726	731	PF02516	0.625
MOD_N-GLC_1	880	885	PF02516	0.590
MOD_N-GLC_2	941	943	PF02516	0.590
MOD_NEK2_1	282	287	PF00069	0.479
MOD_NEK2_1	296	301	PF00069	0.656
MOD_NEK2_1	327	332	PF00069	0.647
MOD_NEK2_1	359	364	PF00069	0.481
MOD_NEK2_1	509	514	PF00069	0.520
MOD_NEK2_1	570	575	PF00069	0.683
MOD_NEK2_1	644	649	PF00069	0.772
MOD_NEK2_1	668	673	PF00069	0.753
MOD_NEK2_1	694	699	PF00069	0.549
MOD_NEK2_1	728	733	PF00069	0.629
MOD_NEK2_1	745	750	PF00069	0.521
MOD_NEK2_1	895	900	PF00069	0.709
MOD_NEK2_1	963	968	PF00069	0.587
MOD_NEK2_2	515	520	PF00069	0.532
MOD_NEK2_2	698	703	PF00069	0.588
MOD_PIKK_1	17	23	PF00454	0.475
MOD_PIKK_1	443	449	PF00454	0.465
MOD_PIKK_1	465	471	PF00454	0.465
MOD_PIKK_1	503	509	PF00454	0.478
MOD_PIKK_1	545	551	PF00454	0.700
MOD_PIKK_1	581	587	PF00454	0.669
MOD_PIKK_1	703	709	PF00454	0.588
MOD_PK_1	46	52	PF00069	0.440
MOD_PK_1	839	845	PF00069	0.497
MOD_PKA_2	1002	1008	PF00069	0.532
MOD_PKA_2	173	179	PF00069	0.554
MOD_PKA_2	327	333	PF00069	0.694
MOD_PKA_2	634	640	PF00069	0.653
MOD_PKA_2	660	666	PF00069	0.679
MOD_PKA_2	755	761	PF00069	0.741
MOD_PKA_2	918	924	PF00069	0.613
MOD_PKA_2	985	991	PF00069	0.577
MOD_PKB_1	160	168	PF00069	0.516
MOD_PKB_1	44	52	PF00069	0.416
MOD_Plk_2-3	66	72	PF00069	0.633
MOD_Plk_2-3	797	803	PF00069	0.660
MOD_Plk_4	1002	1008	PF00069	0.520
MOD_Plk_4	367	373	PF00069	0.389
MOD_Plk_4	46	52	PF00069	0.418
MOD_Plk_4	728	734	PF00069	0.674
MOD_Plk_4	741	747	PF00069	0.517
MOD_Plk_4	839	845	PF00069	0.497
MOD_Plk_4	971	977	PF00069	0.679
MOD_ProDKin_1	440	446	PF00069	0.435
MOD_ProDKin_1	548	554	PF00069	0.641
MOD_ProDKin_1	58	64	PF00069	0.502
MOD_ProDKin_1	661	667	PF00069	0.585
MOD_ProDKin_1	711	717	PF00069	0.725
MOD_ProDKin_1	78	84	PF00069	0.645
MOD_ProDKin_1	887	893	PF00069	0.637
MOD_ProDKin_1	898	904	PF00069	0.585
MOD_ProDKin_1	932	938	PF00069	0.707
MOD_ProDKin_1	954	960	PF00069	0.601
MOD_ProDKin_1	977	983	PF00069	0.605
MOD_ProDKin_1	996	1002	PF00069	0.612
MOD_SUMO_for_1	149	152	PF00179	0.399
MOD_SUMO_for_1	209	212	PF00179	0.366
MOD_SUMO_for_1	947	950	PF00179	0.625
MOD_SUMO_rev_2	49	59	PF00179	0.440
MOD_SUMO_rev_2	765	775	PF00179	0.553
MOD_SUMO_rev_2	942	947	PF00179	0.632
TRG_DiLeu_BaEn_1	186	191	PF01217	0.395
TRG_DiLeu_BaEn_1	243	248	PF01217	0.475
TRG_ENDOCYTIC_2	32	35	PF00928	0.475
TRG_ENDOCYTIC_2	368	371	PF00928	0.361
TRG_ENDOCYTIC_2	442	445	PF00928	0.377
TRG_ENDOCYTIC_2	452	455	PF00928	0.420
TRG_ENDOCYTIC_2	497	500	PF00928	0.475
TRG_ENDOCYTIC_2	522	525	PF00928	0.548
TRG_ER_diArg_1	136	139	PF00400	0.482
TRG_ER_diArg_1	160	162	PF00400	0.459
TRG_ER_diArg_1	279	281	PF00400	0.496
TRG_ER_diArg_1	422	424	PF00400	0.428
TRG_ER_diArg_1	425	428	PF00400	0.375
TRG_ER_diArg_1	43	46	PF00400	0.458
TRG_ER_diArg_1	511	514	PF00400	0.472
TRG_ER_diArg_1	593	596	PF00400	0.604
TRG_ER_diArg_1	600	603	PF00400	0.577
TRG_NLS_MonoExtN_4	560	566	PF00514	0.665

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCG6	Leptomonas seymouri	57%	94%
A4HD00	Leishmania braziliensis	75%	99%
A4I0I5	Leishmania infantum	100%	100%
E9AWE7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QB25	Leishmania major	92%	100%