LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8ICK6_LEIDO
TriTrypDb:
LdBPK_260090.1 * , LdCL_260005900 , LdCL_260006200 , LdCL_260006500 , LDHU3_26.0130 , LDHU3_26.0170
Length:
356

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICK6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICK6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 18 22 PF00656 0.501
CLV_NRD_NRD_1 249 251 PF00675 0.526
CLV_NRD_NRD_1 270 272 PF00675 0.645
CLV_NRD_NRD_1 273 275 PF00675 0.615
CLV_NRD_NRD_1 342 344 PF00675 0.673
CLV_NRD_NRD_1 62 64 PF00675 0.387
CLV_PCSK_FUR_1 246 250 PF00082 0.536
CLV_PCSK_KEX2_1 248 250 PF00082 0.537
CLV_PCSK_KEX2_1 342 344 PF00082 0.712
CLV_PCSK_KEX2_1 62 64 PF00082 0.382
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IIL9 Leptomonas seymouri 59% 89%
A0A0S4IRP2 Bodo saltans 28% 100%
A0A1X0NU99 Trypanosomatidae 40% 100%
A0A422N352 Trypanosoma rangeli 38% 100%
A4HEL6 Leishmania braziliensis 89% 100%
A4I1U9 Leishmania infantum 100% 100%
E9AHA8 Leishmania infantum 100% 100%
E9AXZ2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
Q4Q9I0 Leishmania major 97% 100%
V5DR77 Trypanosoma cruzi 40% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS